Abstract: This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection. wherein: X is C or N with the proviso that when X is N, R1 does not exist; W is C or N with the proviso that when W is N, R2 does not exist; V is C; E is hydrogen or a pharmaceutically acceptable salt thereof; and Y is selected from the group consisting of Also, this invention provides for intermediate Compounds II useful in making prodrug Compounds I. wherein: L and M are independently selected from the group consisting of C1-C6 alkyl, phenyl, benzyl, trialkylsilyl, -2,2,2-trichloroethoxy and 2-trimethylsilylethoxy.

Abstract: This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.

Abstract: Methods and apparatus are provided for framing synchronization control for a framer/mapper/multiplexor (FMM) device with 1+1 and equipment protection. FMM device are disclosed that synchronize one or more internal signals by changing a phase of the one or more internal signals without changing a frequency of the one or more internal signals based on a desired phase at a destination of each of the one or more internal signals. A programmable synchronization signal may optionally be employed for the synchronization.

Abstract: A linear actuator includes a stationary part, a movable part moveably supported by the stationary part, and at least one elastic member disposed between the movable part and the stationary part. The stationary part includes a stator core with a pair of teeth extending inwardly there from, and a winding wound on each of the teeth. The movable part disposed between the teeth includes two pairs of permanent magnetic poles respectively facing the teeth and an output shaft projecting in a first direction. When the windings are electrified, the stationary part generates a magnetic field which interacts with the permanent magnetic poles to reciprocate the movable part relative to the stationary part in a second direction perpendicular to the first direction.

Abstract: An exemplary electronic device includes a casing, a first switch, a second switch and a switch control unit. The casing includes a side plate and a top plate detachably connected with a top end of the side plate. The first switch is turned on when the top plate is connected to the side plate and turned off when the top plate is detached from the side plate. The switch control unit includes a sliding member mounted at one side of the second switch. The sliding member includes a pressing plate. The sliding member is moveable relative to the side plate between a first state in which the pressing plate aligned with and pressing the second switch to turn on the second switch and a second state in which the pressing plate is staggered with the second switch to turn off the second switch.

Abstract: This application discloses a novel process for the preparation of himbacine analogs useful as thrombin receptor antagonists. The process is based in part on the use of a base-promoted dynamic epimerization of a chiral nitro center.

Abstract: An electronic device includes a remote control and a host. The remote control is for generating different wireless signals. The host communicates with the remote control. The host includes a processor, a control panel, and a receiving unit. The control panel is for generating different key signals. The control panel includes a key for generating a locking signal and an unlocking signal. The receiving unit is for transferring the different key signals from the control panel to control the processor, and further for transferring the different wireless signals from the remote control to control the processor. The processor disables the receiving unit according to the locking signal and enables the receiving unit according to the unlocking signal.

Abstract: The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: An exemplary electronic device includes a main housing and a cover pivotably attached to the main housing. The main housing has a printed circuit board received therein. A Hall sensor is fixed and electrically connected to the printed circuit board. The cover has a display and a speaker located adjacent to the display. The speaker includes a magnet. The Hall sensor can detect variation of a magnetic field of the magnet to output different voltages, thereby actuating the display to turn on or turn off.

Abstract: The present invention provides for the use of a dimeric phthalide compound, the dimeric phthalide compound has broad anti-tumor activity, can directly inhibit the proliferation of tumor cells and induce cell death, but also indirectly inhibit the development of tumors by suppressing neovascularization. And further, the dimeric phthalide compound can be used alone or in combination to treat cancer, as well as in combination with chemotherapeutics to increase the efficacy of chemotherapeutics and decrease the toxicity of chemotherapeutics.

Abstract: A communication device comprises a signal combiner, first storage elements, second storage elements and a controller. The signal combiner is configured to combine overhead information with additional information in forming a frame of a signal. The first storage elements are adapted to receive respective portions of a given block of the overhead information to be applied to the signal combiner, and the second storage elements are coupled between respective ones of the first storage elements and respective inputs of the signal combiner. The controller is operative to monitor a count of portions of the frame as the frame is formed by the signal combiner and to control loading of the portions of the given block of the overhead information into the second storage elements from the first storage elements responsive to the monitored count.

Abstract: A foldable computing device with counterbalance member includes a main body, a rotary member, and a shaft. The rotary member is rotatably connected to the main body by the shaft. The main body, from top to bottom, includes a top cover, a printed circuit board, a counterbalance member and a bottom case. The counterbalance is configured to maintain contact with the printed circuit board and the bottom case. Electrostatic charges produced on the printed circuit board can be conducted to the bottom case through the counterbalance member, and then to ground.

Abstract: Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, diketopiperidine derivatives that possess unique antiviral activity are provided. These compounds are useful for the treatment of HIV and AIDS.

Abstract: Compounds having drug and bio-affecting properties are described herein, including their properties, pharmaceutical compositions and methods of use. In particular, tricyclic aryl or heteroaryl piperazine diamide derivatives that possess unique antiviral activity are set forth. These compounds are useful for the treatment of HIV and AIDS.

Abstract: Foliamngiferosides having the general formula (I) are disclosed, wherein R is H or —OCH. The preparation method of the compounds, pharmaceutical compositions comprising the compounds as the active ingredients, the use of the compounds and the pharmaceutical compositions for inhibiting the activity of ?-glucosidase are also disclosed. The foliamangiferosides can be used in preparing drugs for treating diabetes.

Abstract: A Coriolis mass flowmeter with at least four bent measuring tubes, at least one actuator assembly and at least one sensor assembly, wherein a first measuring tube and a second measuring tube are located in a common first plane and a third measuring tube and a fourth measuring tube are located in a common second plane, wherein the first plane and the second plane run parallel to one another, and wherein all four measuring tubes are joined together in terms of flow on the input side and on the output side with a collector. A Coriolis mass flowmeter for large amounts of flow, which is improved in respect to its measurement accuracy, is implemented in that the geometry and/or the surface characteristics of the measuring tubes are set so that the tube flow resistance of all four measuring tubes is identical.

Abstract: An exemplary electronic device includes a casing, a first switch, a second switch and a switch control unit. The second switch is connected in parallel with the first switch. The casing includes a side plate and a top plate detachably connected with a top end of the side plate. The first switch is turned on when the top plate mounted to the side plate and turned off when the top plate detached from the side plate. The switch control unit includes a sliding member mounted at the second switch. The sliding member includes a pressing plate and is moveable relative to the side plate between a first position in which the pressing plate aligned with and pressing the second switch to turn on the second switch and a second position in which the pressing plate is staggered with the second switch to turn off the second switch.

Abstract: Methods and apparatus are disclosed to index digital frames. An example method includes identifying channel types associated with a plurality of image frames, splitting each one of the plurality of image frames into a respective color channel based on the identified channel types, applying a local binary pattern to each of the respective color channels to generate a respective pattern number, generating a spatial representation of each respective pattern number to determine transition probabilities for each channel type, and identifying a degree of similarity between the plurality of image frames based on the transition probabilities.

Abstract: A method for providing a Bluetooth function for a computer is disclosed, including: inputting a switch indication, and a terminal switching a working mode to a Bluetooth adapter mode; connecting the terminal to the computer via a universal serial bus (USB) interface; receiving an upload configuration parameter sent from the computer, and the terminal transmitting configuration parameters stored therein to the computer to enable the computer to regard the terminal as a Bluetooth adapter; the terminal sending an HCI command transmitted via the USB interface by the computer via its Bluetooth chip, converting a radio frequency signal received by its Bluetooth chip into an HCI event to transmit to the computer via the USB interface. Also disclosed in the present invention is a terminal for providing a Bluetooth function for a computer, including a user interface (UI), a switching module, a USB interface, an enumerating module and a Bluetooth module.

Abstract: A layered composition which can be used in various processes has been developed. The composition comprises an inner core such as a cordierite core and an outer layer comprising a refractory inorganic oxide, a fibrous component and an inorganic binder. The refractory inorganic oxide layer can be alumina, zirconia, titania, etc. while the fibrous component can be titania fibers, silica fibers, carbon fibers, etc. The inorganic oxide binder can be alumina, silica, zirconia, etc. The layer can also contain catalytic metals such as gold and platinum plus other modifiers. The layered composition is prepared by coating the inner core with a slurry comprising the refractory inorganic oxide, fibrous component, an inorganic binder precursor and an organic binding agent such as polyvinyl alcohol. The composition can be used in various hydrocarbon conversion processes including production of vinyl acetate.