Abstract: A composite tack film includes a) a first polymer layer including a thermally conductive polymer having a melting temperature of less than about 100° C.; b) a second polymer layer adjacent the first polymer layer, the second polymer layer including a visco-elastic, thermally conductive polymer having a melting temperature of less than about 110° C.; and c) a third polymer layer adjacent the second polymer layer, the third polymer layer including a thermally insulative polymer having a melting temperature of less than about 100° C. Further included is a method of reinforcing pavement with the aforementioned composite tack film.

Abstract: The present invention relates to 4-Pyridinonetriazine Derivatives of Formula (I); and pharmaceutically acceptable salts thereof, wherein A, X, Y, R1, R2, R3 and R5 are as defined herein. The present invention also relates to compositions comprising at least one 4-Pyridinonetriazine Derivative, and methods of using the 4-Pyridinonetriazine Derivatives for treating or preventing HIV infection in a subject.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to an appointment activity business object.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to an email activity business object.

Abstract: The present invention relates generally to chemically prepared toner and method of making the toner for use in electrophotography and more particularly to chemically prepared toner that can simultaneously fix at an energy saving low temperature and also be resistant to hot offset. The chemically prepared toner includes a mixture of a low molecular weight styrene acrylic resin and a low melting polyester resin. The amount of the low melt polyester resin must not exceed 40% by weight of the energy efficient toner of the present invention.

Abstract: Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP) without any polymeric carriers, or with minimal use of polymeric carriers. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles formed of pharmaceutical agents that have a low water solubility. Such methods and compositions can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier.

Abstract: Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP) without any polymeric carriers, or with minimal use of polymeric carriers. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles formed of pharmaceutical agents that have a low water solubility. Such methods and compositions can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier.

Abstract: An EEPROM device, a forming method thereof, and a method for implementing an erase operation to the device are provided. The EEPROM device includes: a semiconductor substrate having active regions therein; a word line disposed on a first active region; float gate dielectric layers disposed on second active regions; float gates disposed on the float gate dielectric layers, wherein each of the float gates has a width larger than that of the second active region; control gates disposed on control gate dielectric layers which are disposed on the float gates; an isolation oxide layer disposed between the word line and the float gates along with the control gates; and bit line doping regions disposed on third active regions. Accordingly, an erase operation can be implemented from a bit line, and coupling ratios of a float gate to a control gate and to a bit line doping region can be improved.

Abstract: A method of sharing virtual machine resources. The method includes: in response to at least one user logging in to the virtual machine, monitoring file operations taken by the user in the virtual machine; recording the types of file operations; in response to the user logging out from the virtual machine, restoring the virtual machine back to the original state at the time when the user logged in to the virtual machine according to the recorded types of file operations; and in response to receiving a request for virtual machine resources, assigning one of the virtual machines which is idle and restored back to the original state to the requesting user.

Abstract: The present invention discloses a method and an apparatus for recommending a suspicious component in problem diagnosis for a cloud application. In the method, firstly a graph data model representing a hierarchical structure of the cloud application is constructed, wherein the graph data model comprises an application node representing the cloud application, a plurality of component nodes representing a plurality of components of the cloud application, and inter-node lines indicating inter-node relationships. Then real-time information of the cloud application is obtained, in response to detecting performance degradation of the cloud application. Impact degrees of the plurality of component nodes on the performance degradation of the cloud application is obtained based on the constructed graph data model and the obtained real-time information, and a suspicious component sequence is generated according to the impact degrees of the plurality of component nodes.

Abstract: The present invention relates to adaptive beamforming in audio systems. More specifically, aspects of the invention relate to a method for adaptively estimating a target sound signal by establishing a simulation model simulating an audio environment comprising: a plurality of spatially separated microphones, a target sound source, and a number of audio noise sources.

Abstract: The present invention relates to Internet and communication technologies, and discloses a method and apparatus for clustering portable executable (PE) files. The method comprises: extracting PE file characteristics from a PE file; generating a PE file identifier for the PE file based on the PE file characteristics; and clustering the PE file base on the PE file identifier. The apparatus comprises an extraction module, a generation module, and a clustering module. In accordance with embodiments of the present invention, a PE file identifier is generated for the PE file based on PE file characteristics extracted from the PE file, and the PE files are clustered based on the PE file identifier. Thus, random PE files are clustered into ordered classes, and the number of PE files to be processed by the antivirus clients and servers are reduced, which reduces storage costs, improves matching efficiency and the ability to detect and combat PE virus variants.

Abstract: Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP) without any polymeric carriers, or with minimal use of polymeric carriers. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles formed of pharmaceutical agents that have a low water solubility. Such methods and compositions can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier.

Abstract: Provided is a 10-methoxycamptothecine derivate of formula (1), wherein R is selected from hydrogen, C1-6 alkyl, C1-6 haloalkyl, aryl substituted C1-6 alkyl, phosphate substituted C1-6 alkyl, amino-substituted C1-6 alkyl, carboxyl substituted C1-6 alkyl, hydroxyl substituted C1-6 alkyl, and amide-substituted C1-6 alkyl; R1 is selected from hydrogen and t-butoxycarbonyl substituted amino. Also provided in the present invention are the preparation method of the derivate and the use thereof in anti-tumor drug preparation.

Abstract: Mucus-penetrating liposomal nanoparticles and methods of making and using thereof are described herein. The nanoparticles contain one or more lipids, one or more PEG-conjugated lipids, and optionally one or more additional materials that physically and/or chemically stabilize the particles. The nanoparticle have an average diameter of about 100 nm to about 300 nm, preferably from about 100 nm to about 250 nm, more preferably from about 100 nm to about 200 nm. The particles are mobile in mucus. The liposomes can further contain one or more therapeutic, prophylactic, and/or diagnostic agent to be delivered to a mucosal surface, such as the CV tract, the colon, the nose, the lungs, and/or the eyes. The liposomes can further contain one or more CEST agents to allow real time imaging of the particles in a live animal. The particles may also further contain an imaging agent, such as a fluorescent label.

Abstract: A method for determining a suspect memory leak, including: sampling the throughput and memory usage of an application server; based on the sampled throughput, monitoring whether the throughput decrease continually, and based on the sampled memory usage, monitoring whether the memory usage remains stable within a predefined range; in response to a continual decrease of the throughput and the memory usage remaining stable within the predetermined range, determining that the application server is suspected of having a memory leak. Using the solution of the present invention can free an administrator of the burden of artificially identifying suspect servers, can identify a suspect server during runtime and further determine whether it actually has a memory leak.

Abstract: A method, apparatus, and manufacture of beamforming is provided. Adaptive null beamforming is performed for signals from first and second microphones of a two-microphone array. The signals from the microphones are decomposed into subbands. Beamforming weights are evaluated and adaptively updated over time based, at least in part, on the direction of arrival and distance of the target signal. The beamforming weights are applied to the subbands at each updated time interval. Each subband is then combined.

Abstract: This invention provides a method and system for data encryption and decryption in data transmission through the web. The method includes: a browser sends a cryptographic information acquisition request to a cryptographic information providing equipment; the cryptographic information providing equipment sends cryptographic information back to the browser via an HTTPS channel; the cryptographic information includes a cryptographic algorithm and a cryptographic index; the browser uses the cryptographic algorithm to encrypt the data to be transmitted, and sends the encrypted data and the cryptographic index to the web server via an HTTP channel; the web server obtains the cryptographic algorithm corresponding to the cryptographic index from the cryptographic information providing equipment, then decrypts the encrypted data. Embodiments of the present invention can alleviate the load in the HTTPS channel, and improve the overall performance.

Abstract: A composite tack film is provided. The composite tack film includes a) a first polymer layer including a thermally conductive polymer having a melting temperature of less than about 100° C.; b) a second polymer layer adjacent the first polymer layer, the second polymer layer including a visco-elastic, thermally conductive polymer having a melting temperature of less than about 110° C.; and c) a third polymer layer adjacent the second polymer layer, the third polymer layer including a thermally insulative polymer having a melting temperature of less than about 100° C. Further included is a method of reinforcing pavement with the aforementioned composite tack film.

Abstract: A method and device for processing data in the field of data process are disclosed. The method includes: sorting samples according to primary keys, wherein the primary key includes a feature serial number and a sample serial number, and wherein a column value corresponding to the primary key is used as a feature value for the sample; acquiring a statistic of each feature in each category by taking the primary key and the feature value as an input key-value pair and calculating with a first algorithm model, and outputting the feature serial number and the statistic as an output key-value pair; and acquiring a contribution value of each feature to the category by performing calculation on the output key-value pair with a second algorithm model, and selecting a feature based on the contribution value. The device includes a sorting module, a first processing module and a second processing module.