Abstract: A layer system including a substrate and a layer is provided. The layer system has a hole at least in the layer, and wherein at least one recess is present in a surface of the layer in a vicinity around the hole or directly adjoining a boundary line of the hole.

Abstract: Aspects of the subject matter described herein relate to file system placeholders. In aspects, placeholders may be used by a client to represent remote file system objects. The placeholders may include metadata, searchable text, and may also include none, some, or all of the content of the represented remote file system objects. Search data from the placeholders is integrated into a local search database of the client such that the client is able to satisfy queries and identify relevant local and remote file system objects even when the client is offline with respect to remote storage.

Abstract: The present application relates to an atraumatic sternal plate for haemostasis for a retractor with a pressure plate and a retaining device attached to the pressure plate. The pressure plate can be attached, by means of the retaining device, to either the blades of a retractor or to a sternal half of the patient, so that the pressure plate abuts the sagittal incision surface of a sternal half when spreading the sternum of a patient by means of a retractor.

Abstract: A method for establishing a magnetic resonance system actuation sequence is described. A first number of field distribution maps are acquired for slices of the measurement region, and a radiofrequency pulse train is established on the basis thereof for the magnetic resonance system actuation sequence. This acquisition of the first number of field distribution maps may be brought about on the basis of an acquisition scheme. A reduced number of field distribution representation maps are established on the basis of the acquired field distribution maps, which field distribution representation maps represent the first number of acquired field distribution maps in accordance with a predetermined optimization criterion, and the radiofrequency pulse train is established on the basis of the field distribution representation maps.

Abstract: Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.

Abstract: A method and a computer system are disclosed for automatically generating a statistical vascular model of a patient group. In at least one embodiment, the method includes collecting determining patient-related vascular coordinates models from a multiplicity of vascular landmark coordinates of vascular landmarks, centerline coordinates on vessel centerlines and vessel contour coordinates on vessel contour edge profiles; determining body landmark coordinates of body landmarks; registering the vessel-related coordinates to patient-related registered vascular coordinates models; merging patient-related vascular parameter models to form at least one statistical vascular parameter model; determining the statistical parameters thereof; and saving and/or outputting the at least one statistical vascular parameter model.

Abstract: The invention relates to a system and method of communication between optical transceivers in an optical WDM network, wherein a broad-band modulation of optical signals in a primary frequency band is utilized for transmitting primary high-speed data, while a plurality of relatively low-frequency in-band subcarriers is used to modulate the optical signals to transmit secondary data between network nodes, wherein the plurality of low-frequency subcarriers lie at least in part within the primary frequency band.

Abstract: The disclosure provides chimeric West Nile/Dengue viruses comprising non-coding regions, non-structural proteins, and a C protein from a West Nile virus and prM and E proteins from a Dengue virus. Also disclosed are methods of using the chimeric viruses in diagnosis of Dengue viral infection, assessment of candidate Dengue virus vaccine efficacy, and production of Dengue prM and E proteins.

Abstract: Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.

Abstract: A method and a computer system are disclosed for automatic vectorization of the profile of a vessel tree and at least one of its properties on the basis of tomographic images of an examined patient. In at least one embodiment, using previously established location probabilities of landmarks in the vessel tree, there is an automatic determination of a plurality of distinctive landmarks in the current tomographic image data record of the patient, a registration of the current tomographic image data record to the statistical vessel model, an automatic determination of previously unidentified landmarks in the registered tomographic image data record using characteristic identification features of the previously unidentified landmarks from the statistical vessel model and the statistical location probability thereof, and a determination of at least one current vessel model using the identified landmarks and at least one vessel property at and/or between the identified landmarks.

Abstract: There are a multiplicity of methods of making through-holes. In particular in the production of a multiplicity of film-cooling holes, as in gas turbine blades or combustion chamber elements, small time advantages are also important when making a hole. The method according to the invention, to make the hole close to the final contour in each case in sections in a top and a bottom region in order to then produce the final contour with other laser parameters, achieves time advantages.

Abstract: There are a multiplicity of methods of making through-holes. In particular in the production of a multiplicity of film-cooling holes, as in gas turbine blades or combustion chamber elements, small time advantages are also important when making a hole. The method according to the invention, to make the hole close to the final contour in each case in sections in a top and a bottom region in order to then produce the final contour with other laser parameters, achieves time advantages.

Abstract: There are a multiplicity of methods of making through-holes. In particular in the production of a multiplicity of film-cooling holes, as in gas turbine blades or combustion chamber elements, small time advantages are also important when making a hole. The method according to the invention, to make the hole close to the final contour in each case in sections in a top and a bottom region in order to then produce the final contour with other laser parameters, achieves time advantages.

Abstract: An optical transceiver that includes a modification that prevents interoperability with standard transceivers, while enabling them to work in the same slots and equipment as standard transceivers, provided that they are interoperating with a similarly modified transceiver on the other end of the optical link. Ideally, the polarity of the data in both the transmit and receive direction is inverted resulting in valid data for a link when a pair of modified modules are used and invalid data when a modified module is used with a standard fiber optic transceiver. The function is otherwise transparent to the host equipment.

Abstract: A method is disclosed for determining a boundary surface network of a tubular object. An ordered series of contours is first supplied on the basis of image data in a source space. A transformation function is created for at least two consecutive contours in the series, and a unit space segment object is created in the unit space on the basis of the consecutive contours. A local signed distance function is determined in the unit space. In addition, a relative positional information of a query point is determined in the source space from a surface of a segment object in the source space, the segment object being based on the consecutive contours, on the basis of the local signed distance function in the unit space and using the transformation function. Finally, the boundary surface network is created on the basis of the relative positional information that has been determined.

Abstract: Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.

Abstract: Conventionally coated components with film cooling holes are known, comprising a diffuser, extending through the layers into the substrate. According to the invention, the component is embodied such that the whole diffuser is largely arranged in the layer.

Abstract: A method and a computer system are disclosed for automatically generating a statistical vascular model of a patient group. In at least one embodiment, the method includes collecting specifying patient-related vascular coordinates models from a multiplicity of vascular landmark coordinates of vascular landmarks, centerline coordinates on vessel centerlines and vessel contour coordinates on vessel contour edge profiles; specifying body landmark coordinates of body landmarks; registering the vessel-related coordinates to patient-related registered vascular coordinates models; merging patient-related vascular parameter models to form at least one statistical vascular parameter model; specifying the statistical parameters thereof; and saving and/or outputting the at least one statistical vascular parameter model.

Abstract: There is described a method for producing a hole using e.g. a lasers, wherein short laser pulse durations are used. The laser pulse durations are varied, short laser pulse durations being utilized only in the area to be removed in which an influence on the penetration behavior and discharge behavior is noticeable while longer pulse durations of >0.4 ms are used. This is the case for the inner surface of a diffuser of a hole, for example, which can be produced very accurately by means of short laser pulse durations.

Abstract: There are a multiplicity of methods of making through-holes. In particular in the production of a multiplicity of film-cooling holes, as in gas turbine blades or combustion chamber elements, small time advantages are also important when making a hole. The method according to the invention, to make the hole close to the final contour in each case in sections in a top and a bottom region in order to then produce the final contour with other laser parameters, achieves time advantages.