Abstract: The invention relates to a transmission (100) for a hybrid drive arrangement which can be coupled to two drive assemblies (7, 8), comprising an input shaft (10), and an output shaft (11), at least one first, second, third, fourth, fifth and sixth shifting element (SE1, SE2, SE3, SE4, SE5, SE6), and at least one planetary gear (5).

Abstract: A method for rating a software component of a software-in-the-loop (SiL) environment, a target hardware including at least one target hardware component being simulated by an SiL environment including at least one corresponding software component, both the target hardware and the SiL environment being subjected to a test situation, while the target hardware and the SiL environment are being subjected to the test situation, output data being generated in each case by both the target hardware and the SiL environment and the output data of the target hardware being compared to the outputs of the SiL environment, the software component being rated on the basis of the comparison.

Abstract: The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.

Abstract: Systems and methods for structuring metadata associated with digital media content such as images and videos are disclosed. Use of an existing hierarchical taxonomy provides a set of structured metadata to organize unstructured data stored in an electronic media archive. As digital media content is submitted to the archive, metadata keywords are user-selected from the existing taxonomy to identify and describe the digital media content, and to position the content within the hierarchical structure. The selected metadata keywords can then be automatically associated with synonyms and related terms to build an ontological network that facilitates efficient retrieval of the content when searching the electronic media archive. Each node in the taxonomy is then linked to its foreign language counterparts, allowing the content to be located in an international search.

Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD33. The invention also relates to chimeric antigen receptor (CAR) specific to CD33, vectors encoding the same, and recombinant T cells comprising the CD33 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD33 binding domain.

Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.

Abstract: The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.

Abstract: The present disclosure relates to antibodies and proteins comprising an antigen-binding portion thereof that specifically bind to the pro-inflammatory cytokine IL-17 A. The disclosure more specifically relates to specific antibodies and proteins that are IL-17 A antagonists (inhibit the activities of IL-17 A and IL-17 AF) and are capable of inhibiting IL-17 A induced cytokine production in in vitro assays, and having an inhibitory effect in an antigen-induced arthritis model in vivo. The disclosure further relates to compositions and methods of use for said antibodies and proteins to treat pathological disorders that can be treated by inhibiting IL-17A or IL 17AF mediated activity, such as rheumatoid arthritis, psoriasis, systemic lupus erythematosus (SLE), lupus nephritis, chronic obstructive pulmonary disease, asthma or cystic fibrosis or other autoimmune and inflammatory disorders.

Abstract: A floor module for an aircraft cargo hold including a cover element and a floor element which is spaced apart from the cover element at least in some segments and which is attached to an underside of the cover element. The cover element includes receiving openings for receiving ball elements. The cover element and the floor element can be formed as a hybrid composite part.

Abstract: Disclosed is a print head coater module 10 for a 3D printer, comprising a print head 12, a coater 14 having a container 16 defining an inner cavity 18 for receiving particulate material and opening into an output opening from which the particulate material can be output, and a roller assembly 20 arranged between the container 16 and the print head 12, and a common support structure 22 to which the print head 12, the container 16 and the roller assembly 20 are attached, so that the print head 12, the container 16 and the roller assembly 20 can be moved together over a construction space of the 3D printer.

Abstract: The invention relates to a transfer system for transferring an item with a transfer assembly for transferring an item to a transporting carriage in a transfer area and with a transporting carriage for receiving the item from the transfer assembly in the transfer area.

Abstract: The invention relates to a material roll preparation arrangement. The material roll preparation arrangement comprises a receiving apparatus for receiving a material roll to be prepared with a wound material web, and at least one material roll preparation apparatus which is assigned to the receiving apparatus for the preparation of the material roll which is received in the receiving apparatus for further processing, in particular in a corrugator plant.

Abstract: The invention relates to an automated transfer assembly for transferring goods, having a frame, having a repositioning installation which for repositioning the frame is disposed on the frame, and having a gripping device which for gripping an item of goods is in connection with the frame. The gripping device comprises a first gripper arm installation for engaging on the item of goods to be gripped, and a second gripper arm installation for engaging on the item of goods to be gripped, said second gripper arm installation being spaced apart from the first gripper arm installation. The transfer assembly furthermore has a control unit for controlling automated gripping of the item of goods to be gripped by means of the gripping device.

Abstract: A drive device and methods for operating a drive device of a motor vehicle, having an internal combustion engine, an electric machine, and a dual-clutch transmission. The dual-clutch transmission has two clutches, by means of which the transmission can be connected to the internal combustion engine. At least the internal combustion engine is actuated in a driving operation in order to generate a target drive torque, and the clutches are actuated in opposite directions for a gear shift. During a gear shift, the electric machine, which is connected to the dual-clutch transmission without a clutch, is actuated such that the electric machine completely or partly generates the target torque at least temporarily.

Abstract: The invention relates to a transmission (100) for a hybrid drive arrangement which can be coupled to two drive assemblies (7, 8), comprising an input shaft (10) and an output shaft (11), at least one first and one second shifting element (SE1, SE2) and at least one double planetary gear (5). The input shaft (10) is connected to the planetary carrier of the double planetary gear (5) and the output shaft (11) can be coupled to the first ring gear of the double planetary gear (5) by means of the first shifting element (SE1) and can be coupled to the second ring gear of the double planetary gear (5) and by means of the second shifting element (SE2).

Abstract: A slinger, or slinger ring, for a melt spinning apparatus has a cylindrical, mechanically shaped main element that is composed of a refractory metal or a refractory metal-based alloy and has a circumferential surface running in a tangential direction. The circumferential surface is delimited in the axial direction by two end faces. A degree of deformation in the radial direction is greater than the degree of deformation in the axial direction.

Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.

Abstract: The invention relates to a transmission (100) for a hybrid drive arrangement which can be coupled to two drive assemblies (7, 8), comprising an input shaft (10), and an output shaft (11), at least one first, second and third shifting element (SE1, SE2, SE3), and at least one first planetary gear (5). The input shaft (10) can be coupled to a first transmission shaft (16) by means of the first shifting element (SE1). The first transmission shaft (16) can be coupled to the sun gear of the planetary gear (5) by means of the second shifting element (SE2) and the ring gear of the planetary gear (5) is coupled to the first transmission shaft (16). The input shaft (10) can be coupled to the sun gear of the planetary gear (5) by means of the third shifting element (SE3). The output shaft (11) is coupled to the planet carrier of the planetary gear (5).

Abstract: A mounting device for mounting functional devices within a cargo hold of an aircraft. The mounting device includes at least one surface unit and a plurality of functional devices which can be mounted on the surface unit in such a way that the surface unit can be inserted together with functional devices mounted thereon into the aircraft cargo hold in the manner of a template in such a way that all the functional devices come to lie in defined mounting locations in the cargo hold and can be mounted on supporting structures of the aircraft or the cargo hold without adjustment in relation to the surface unit.

Abstract: Disclosed is a coater assembly 1 for a 3D printer, comprising a coater 3 having a container 5 which defines an inner cavity for receiving particulate construction material which opens into a container opening 7 for outputting the particulate construction material from the container 5, and an output region 9 which defines a coater output opening 11 for outputting the particulate construction material from the coater 3 onto a construction field. The container 5 is movable relative to the coater output opening 11 so that by moving the container 5 relative to the coater output opening a discharge of particulate construction material from the inner cavity through the container opening 7 and the coater output opening 11 onto the construction field is variable.