Patents by Inventor Thomas Maier

Thomas Maier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolidinone derivatives as GPR119 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders
    Patent number: 8853412
    Abstract: The present invention relates to pyrrolidinone derivatives. The pyrrolidinone derivatives are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of pyrrolidinone derivatives as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: October 7, 2014
    Assignee: Sanofi
    Inventors: Lothar Schwink, Martin Bossart, Heiner Glombik, Matthias Gossel, Dieter Kadereit, Thomas Klabunde, Thomas Maier, Siegfried Stengelin
  • N-sulphonylpyrroles and their use as histone deacetylase inhibitors
    Patent number: 8815855
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: August 26, 2014
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Bär, Thomas Beckers, Astrid Zimmermann, Siegfried Schneider, Volker Gekeler
  • VALVE FOR OPENING A FLUID LINE
    Publication number: 20140217313
    Abstract: A valve for one-time opening a fluid line for venting a technical system includes an inlet for connecting to the fluid line, an outlet, and a controllable closure arranged between the inlet and the outlet. In the non-activated state the controllable closure closes a passage between the inlet and the outlet. The closure includes a material that changes its phase state in dependence on a control parameter, whereby the passage is irreversibly opened in the activated state.
    Type: Application
    Filed: February 5, 2014
    Publication date: August 7, 2014
    Applicant: Astrium GmbH
    Inventors: Rainer KILLINGER, Markus Wolf, Thomas MAIER
  • Method for the production of sulphonylpyrroles as HDAC inhibitors
    Patent number: 8785659
    Abstract: Process for the preparation of a compound of formula (I) wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, comprising the step of reacting an acrylic acid chloride compound of formula (II?): wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, with aqueous hydroxylamine and optionally converting the resulting compound into an acid addition salt thereof.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: July 22, 2014
    Assignee: 4SC AG
    Inventors: Matthias Müller, Bernd Müller, Thomas Maier
  • Wheel Fender
    Publication number: 20140175838
    Abstract: A fender (3b) for a wheel on an agricultural vehicle having a cab, said fender comprising an inner contour (3d) proximal to the vehicle for attachment to the cab and a distal outer contour (3e) wherein the outer contour is radially inclined with respect to the inner contour.
    Type: Application
    Filed: November 24, 2011
    Publication date: June 26, 2014
    Inventors: Johann Epple, Paul Frei, Thomas Maier
  • NOVEL PHTHALAZINONE-PYRROLOPYRIMIDINECARBOXAMIDE DERIVATIVES
    Publication number: 20140112945
    Abstract: The compounds of formula (1) in which R1, R7, R8, R9, R10, R17, R18, R19, R20 and m have the meanings as given in the description, are novel effective inhibitors of type 4 and type 5 phosphodiesterase.
    Type: Application
    Filed: June 12, 2012
    Publication date: April 24, 2014
    Applicant: TAKEDA GmbH
    Inventors: Thomas Stengel, Thomas Maier, Alexander Mann, Josef Stadlwieser, Dieter Flockerzi, Andreas Pahl, Ewald Benediktus, Manuela Hessmann, Tobias Kanacher, Ragna Hussong, Christof Zitt, Hans Christof Holst, Rolf-Peter Hummel, Martin Viertelhaus, Hermann Tenor, Torsten Dunkern, Armin Hatzelmann, Christian Hesslinger
  • PYRROLIDINONE DERIVATIVES AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS
    Publication number: 20140099333
    Abstract: The present invention relates to pyrrolidinone derivatives. The pyrrolidinone derivatives are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of pyrrolidinone derivatives as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
    Type: Application
    Filed: October 8, 2013
    Publication date: April 10, 2014
    Applicant: SANOFI
    Inventors: Lothar SCHWINK, Martin BOSSART, Heiner GLOMBIK, Matthias GOSSEL, Dieter KADEREIT, Thomas KLABUNDE, Thomas MAIER, Siegfried STENGELIN
  • FUSED BICYCLIC IMIDAZOLES
    Publication number: 20140088110
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the imidazole to which it is fused, R4, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Application
    Filed: November 26, 2013
    Publication date: March 27, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GmbH
    Inventors: Swen HÖLDER, Armin ZÜLCH, Thomas BÄR, Thomas MAIER, Astrid ZIMMERMANN, Thomas BECKERS, Volker GEKELER, Hemant JOSHI, Yogesh MUNOT, Umesh BHISE, Sunil CHAVAN, Sachin SHIVATARE, Sarvesh PATEL, Vikas GORE
  • PRINTED CIRCUIT BOARD FOR A DOMESTIC APPLIANCE, DOMESTIC APPLIANCE, AND A METHOD FOR OPERATING A DOMESTIC APPLIANCE
    Publication number: 20140083993
    Abstract: A printed circuit board for a domestic appliance includes at least one conductive path which is provided on at least one of two sides of the printed board and adapted for supply with a load current. The printed circuit board has at least one magnetic field sensor which is configured and disposed to read a magnetic field that can be generated by the load current. The load current flowing through the at least one conductive path of the printed circuit board can be detected by contactless reading of the magnetic field generated by the load current through the at least one conductive path.
    Type: Application
    Filed: May 8, 2012
    Publication date: March 27, 2014
    Applicant: BSH BOSCH UND SIEMENS HAUSGERATE GMBH
    Inventors: Thomas Maier, Stefan Schmal, Peter Schuhback
  • Device for Regulating the Pressure and/or Mass Flow for a Space Propulsion System
    Publication number: 20140061517
    Abstract: A device for regulating pressure and/or mass flow of a gaseous or liquid fluid conveyed through a line in a space propulsion system includes a first, piezoelectrically actuatable regulating valve and at least two second, magnetically actuatable regulating valves. The regulating valves are connected to each other and to a line input in such a way that in a nominal mode the pressure and the mass flow of the fluid can be set by the first regulating valve, and a connection or isolation of the first regulating valve with or from the line input can be produced by the second regulating valves. In an emergency mode the pressure and the mass flow of the fluid can be set by the second regulating valves.
    Type: Application
    Filed: September 4, 2013
    Publication date: March 6, 2014
    Applicant: Astrium GmbH
    Inventor: Thomas MAIER
  • MASS SPECTROMETRIC DIAGNOSIS OF SEPTICEMIA
    Publication number: 20140051117
    Abstract: The invention mainly relates to the mass spectrometric identification of pathogens in blood cultures from bloodstream infections (septicemia). The invention provides a method with which microbial pathogens can be separated in purified form from blood after a relatively brief cultivation in a blood culture flask, without any interfering human proteins or any residual fractions of blood particles such as erythrocytes and leukocytes, and can be directly identified by mass spectrometric measurement of their protein profiles. The method is based on the use of relatively strong tensides to destroy the blood particles by dissolving the weak cell membranes and most of the internal structures of the blood particles; in spite of the fact that tensides are regarded as strong ionization inhibitors in MALDI and other ionization processes required for mass spectrometric measurements.
    Type: Application
    Filed: October 28, 2013
    Publication date: February 20, 2014
    Inventor: Thomas Maier
  • Control device for a motor and method for controlling said motor
    Patent number: 8618755
    Abstract: A control device is for a motor, especially a brushless DC motor. The control device contains a bridge circuit for generating a rotating field for the motor and a sensor system for detecting a position of a rotor of the motor, a control signal for the bridge circuit being derivable from the signal representing the rotor position. The sensor system includes an absolute value transmitter which detects the absolute position of the rotor and which is configured to derive at least one incremental signal from the absolute position and to make it directly available to a control component for controlling the bridge circuit for commuting the motor.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: December 31, 2013
    Assignee: Continental Automotive GmbH
    Inventors: Thomas Maier, Christoph Schikora, Thomas Wiercioch
  • Fused bicyclic imidazoles
    Patent number: 8592591
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the imidazole to which it is fused, R4, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Grant
    Filed: August 14, 2008
    Date of Patent: November 26, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Swen Hölder, Armin Zülch, Thomas Bär, Thomas Maier, Astrid Zimmermann, Thomas Beckers, Volker Gekeler, Hemant Joshi, Yogesh Munot, Umesh Bhise, Sunil Chavan, Sachin Shivatare, Sarvesh Patel, Vikas Gore
  • Sample preparation for ionization with matrix-assisted laser desorption
    Patent number: 8592759
    Abstract: A simplified sample preparation on a sample support for ionization with laser desorption (MALDI or LDCI, for example) includes depositing an analyte material onto a deposition site, providing a sample site which is intended as the substrate for a matrix crystal layer at a distance from the deposition site, and establishing a liquid communication between the deposition site and the sample site. A device for the preparation of samples for ionization with matrix-assisted laser desorption, and a sample support for use with the inventive method are also disclosed.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: November 26, 2013
    Assignee: Bruker Daltonik GmbH
    Inventor: Thomas Maier
  • MASS SPECTROMETRIC IDENTIFICATION OF HYPHAL FUNGI
    Publication number: 20130309712
    Abstract: A method is provided for identifying a hyphal fungus in a sample by similarity comparisons between a mass spectrum of the fungus and reference spectra. The method includes growing fresh hyphae without any adhering contact to surfaces as to form a mycelium with undifferentiated hyphae cells. A sample is prepared from the hyphae cells, and a mass spectrum is acquired of the hyphae cell sample. The mass spectrum is matched with at least one reference spectrum.
    Type: Application
    Filed: May 18, 2012
    Publication date: November 21, 2013
    Inventor: Thomas Maier
  • N-substituted tetrahydroisoquinoline/isoindoline hydroxamic acid compounds
    Patent number: 8575193
    Abstract: Compounds of a certain formula (I) wherein R1, R2, R3, X, Y, r, s, t, u and v have the meanings as defined in the specification, and the salts, solvates and hydrates thereof are novel effective HDAC 6 inhibitors.
    Type: Grant
    Filed: March 12, 2009
    Date of Patent: November 5, 2013
    Assignee: 4SC AG
    Inventors: Thomas Maier, Christian Hesslinger, Barbara Beckers
  • Mass spectrometric diagnosis of septicemia
    Patent number: 8569010
    Abstract: The invention mainly relates to the mass spectrometric identification of pathogens in blood cultures from blood-stream infections (septicemia). The invention provides a method with which microbial pathogens can be separated in purified form from blood after a relatively brief cultivation in a blood culture flask, without any interfering human proteins or any residual fractions of blood particles such as erythrocytes and leukocytes, and can be directly identified by mass spectrometric measurement of their protein profiles. The method is based on the use of relatively strong tensides to destroy the blood particles by dissolving the weak cell membranes and most of the internal structures of the blood particles; in spite of the fact that tensides are regarded as strong ionization inhibitors in MALDI and other ionization processes required for mass spectrometric measurements.
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: October 29, 2013
    Assignee: Bruker Daltonik GmbH
    Inventor: Thomas Maier
  • (E)-N-(2-amino-phenyl)-3-{1-[4-(l-methyl-1H-pyrazol-4-yl)-benzenesulfonyl]-1H-pyrrol-3-yl}-acrylamide salts
    Patent number: 8557858
    Abstract: A salt of (E)-N-{2-amino-phenyl)-3-{1-[4-(1-methyl-1 H-pyrazol-4-yl)-be?zenesulfonyl]-1 H-pyrrol-3-yl)-acrylamide selected from the group consisting of the hydrobromide, methansulfonate, hemi ethane-1,2-disulfonate, benzenesulfonate, toiuenesulfonate and 2-naphthalenesulfonate.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: October 15, 2013
    Assignee: 4SC AG
    Inventors: Jürgen Volz, Martin Feth, Rolf-Peter Hummel, Matthias Müller, Thomas Maier, Bernd Müller
  • DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
    Publication number: 20130131034
    Abstract: The instant invention relates to derivatives of formula (I) and their application in therapeutics.
    Type: Application
    Filed: March 1, 2011
    Publication date: May 23, 2013
    Applicant: SANOFI
    Inventors: Markus Follmann, Pascale Goberville, Stéphanie Hachtel, Gerhard Hessler, Heinz-Werner Kleemann, Thomas Maier, Gary MC Cort, Carsten Struebing, Bérangère Thiers, Li-Hsing Wang
  • Tetrahydro-fused pyridines as histone deacetylase inhibitors
    Patent number: 8440830
    Abstract: The compounds of formula (I), wherein ring D and ring E together form a fused ring system selected from formula (II), (III), (IV), (V), (VI), (VII), and the salts of these compounds are novel, effective inhibitors of histone deacetylases.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: May 14, 2013
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Matthias Vennemann, Volker Gekeler, Astrid Zimmermann, Petra Gimmnich, Kamlesh Padiya, Hemant Joshi, Uday Joshi, Mahindra Makhija, Dipak Harel