Abstract: A frame lock for a two-wheeler comprises a lock body, which comprises a latch and a rotary hoop arrangement having a rotary hoop and a strip. The rotary hoop extends along a circular path, has a blocking structure comprising an abutment section, and is adjustable relative to the lock body along the circular path between an open position, in which the rotary hoop releases a wheel of the two-wheeler for a rotation, and a closed position in which the rotary hoop blocks the wheel against rotation. The latch is adjustable between an unlocked position and a locked position and, when the rotary hoop is in its closed position and the latch is in its locked position, the latch engages behind the abutment section, whereby it blocks the rotary hoop against an adjustment into the open position.

Abstract: Methods for producing an object by generative manufacturing, a component, and a computer-readable medium. In one method, a sheet-like part is formed with bulges. In another method, a supporting structure is formed with an arch formed by arch segments converging in the buildup direction and meet at an arch tip. In another method, a supporting structure is formed with a strut of a cloverleaf-like cross-sectional shape. In another method, a supporting structure is formed with a sheet-like part connected to the object and formed to project obliquely forward from the object in the buildup direction. In another method, a supporting structure is formed with a sheet-like part extending substantially along the buildup direction, the sheet-like part formed with apertures.

Abstract: A vaporizer cartridge, as a component of an inhaler, has a hollow body with a continuous flow channel and a storage tank for storing liquid. The storage tank has at least one access opening to the flow channel and a vaporizer unit arranged in the region of the access opening and extending over the entire access opening. The vaporizer unit has a wick member and a heating member. The vaporizer unit is formed to be liquid-permeable such that liquid can be conveyed at least initially in a capillary manner out of the storage tank through the vaporizer unit in the direction of the flow channel. The wick member is formed from a plurality of granular grains which form microchannels as a result of their fill and/or formation. An inhaler is also provided.

Abstract: A vaporizer cartridge for an inhaler has a hollow body with a continuous flow channel and liquid storage tank. The tank has an access opening to the channel and a vaporizer unit extending over the entire access opening. The vaporizer unit has a wick member and a heating member. The vaporizer unit is liquid-permeable such that liquid is conveyed at least initially in a capillary manner from the storage tank through the vaporizer unit in the direction of the flow channel. The wick member is formed from a plurality of granular grains which, as a result of their fill and/or formation, form microchannels which establish a fluid connection between the storage tank and the flow channel, continuously from an entry side to an exit side of the wick member. An additional securing means is provided which is holds the granular wick member in position. A corresponding inhaler is also provided.

Abstract: A method for measuring a workpiece by a measurement device includes capturing an identification feature of a workpiece by a capture device, determining an item of identity information relating to the workpiece, comparing the identity information with identity information relating to a plurality of workpieces from a database which stores the identity information relating to the plurality of workpieces, identifying the workpiece in the database, and/or characterizing the workpiece from the comparison with the database, determining a measurement sequence stored in the database for the identified workpiece, or suggesting features or steps of a measurement sequence for the identified workpiece, and measuring the workpiece in accordance with the measurement sequence in the measurement device.

Abstract: A flexible, scalable, and fast query system for a distributed execution environment is provided. An example method includes receiving a plurality of processor summaries, each including a list of job digests, each job digest including a job identifier for a job running on a job processor and a payload portion. The method can also include, for each job digest, determining a location in a probabilistic payload data structure for the job digest and storing the payload portion and a fingerprint portion generated from a portion of a hash of the job identifier in an entry at the location as a job summary and responding to queries using the probabilistic payload data structure. Responding to a particular query may include identifying job properties corresponding to parameters of the particular query, updating job property statistics, and using the job property statistics to change the job properties represented in the payload portion.

Abstract: A method of inhibiting GAPDH with N-methylol transfer agents and/or related compounds.

Abstract: A method of preventing, inhibiting or reducing cytokine release and the incidence of a cytokine release syndrome (CRS) or a cytokine storm in a subject with certain oxathiazin-like compounds and/or related compounds.

Abstract: A child seat for mounting on a motor vehicle seat is comprised of at least one contact surface device for a child accommodated in the child seat, the contact surface device having at least a first section and a second section, the second section being transferable relative to the first section from a first position to a second position by the action of an at least partially outwardly directed force acting on the second section to damp deceleration of the child in the case of a displacement of the child towards the second section.

Abstract: A method of inhibiting GAPDH with certain oxathiazin-like compounds and/or related compounds.

Abstract: A method for monitoring, evaluating and controlling a cyclic chromatographic purification process that involves at least two adsorbers. According to the method, one step is monitoring of the chromatogram, including the measurement of at least one current concentration-proportional signal in the liquid. Another step is conducting an evaluation of the chromatogram, including a comparison of at least one of the current concentration-proportional signals measured in the monitoring step with a threshold value thereof. A further step is controlling the chromatographic purification process by adapting the termination of the currently running phase as a function of the comparison of the evaluation step and initiating the next phase. Finally, according to the method, the sequence of steps is carried out in given order at least twice.

Abstract: Systems and methods for pre-training and fine-tuning of neural-network-based language models to reason directly over tables without generating logical forms. In some examples, a language model can be pre-trained using masked-language modeling tasks synthetically generated from tables pulled from a knowledge corpus. In some examples, the language model may be further pre-trained using pairs of counterfactual statements generated from those tables, and/or one or more statements that compare selected data from those tables. The language model may then be fine-tuned using examples that include only a question, an answer, and a table, allowing fine-tuning examples to be harvested directly from existing benchmark datasets or synthetically generated.

Abstract: A mixer device for an exhaust system of an internal combustion engine includes a tubular carrier (30) enclosing a mixer longitudinal axis (A) in a ring shape configuration and a mixer insert (28) carried at the carrier (30). The mixer insert (28) has a plurality of connection attachments (52, 54, 56) located at spaced locations from one another in relation to the mixer longitudinal axis (A) radially on the outside. The carrier (30) has a plurality of connection recesses (60, 62) for the permanent connection of the mixer insert (28) to the carrier (30).

Abstract: A fully-connected neural network may be configured for execution by a processor as a fully-fused neural network by limiting slow global memory accesses to reading and writing inputs to and outputs from the fully-connected neural network. The computational cost of fully-connected neural networks scale quadratically with its width, whereas its memory traffic scales linearly. Modern graphics processing units typically have much greater computational throughput compared with memory bandwidth, so that for narrow, fully-connected neural networks, the linear memory traffic is the bottleneck. The key to improving performance of the fully-connected neural network is to minimize traffic to slow “global” memory (off-chip memory and high-level caches) and to fully utilize fast on-chip memory (low-level caches, “shared” memory, and registers), which is achieved by the fully-fused approach.

Abstract: A real-time neural radiance caching technique for path-traced global illumination is implemented using a neural network for caching scattered radiance components of global illumination. The neural (network) radiance cache handles fully dynamic scenes, and makes no assumptions about the camera, lighting, geometry, and materials. In contrast with conventional caching, the data-driven approach sidesteps many difficulties of caching algorithms, such as locating, interpolating, and updating cache points. The neural radiance cache is trained via online learning during rendering. Advantages of the neural radiance cache are noise reduction and real-time performance. Importantly, the runtime overhead and memory footprint of the neural radiance cache are stable and independent of scene complexity.

Abstract: Methods of treating cancer by administering a compound of Formula I, or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments are described, wherein R1 is halo; R2 is halo; and Q is CH or N.

Abstract: The present application relates to novel (imidazo[1,2-a]pyridin-3-yl)methyl-substituted diazaheterobicyclic compounds, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of respiratory disorders including sleep-related respiratory disorders such as obstructive sleep apnoea and central sleep apnoea and snoring. The present application further relates to a method of discovering a compound having TASK-1- and/or TASK-3-blocking properties.

Abstract: A pressure sensor comprises a housing, a flexible membrane which, together with the housing, forms a hermetically closed cavity, a sensor element arranged in the cavity, and a gaseous medium in the cavity.

Abstract: What are described are compounds of the general formula (I) and agrochemically acceptable salts thereof and their preparation and their use in the crop protection sector.