Abstract: Methods, apparatus, systems, and articles of manufacture to make and/or process a diagnostic test device are disclosed. An example apparatus includes a porous media include a first zone and a second zone, the first zone including immobilized antigens corresponding to a target analyte or immobilized antibodies corresponding to the target analyte; a wireless chip to: wirelessly obtain a first voltage via a signal from an external device; output a second voltage smaller than the first voltage to a first electrode in contact with at least one of the first zone or the second zone; and measure an electrical signal from the first electrode, the electrical signal corresponding to presence of the target analyte.

Abstract: The invention relates to a buoyancy force utilization device for converting kinetic buoyancy energy and/or potential energy into an electrical and/or mechanical energy, a temperature barrier device and a method for converting thermal energy into electrical energy, wherein the invention utilizes the cyclic lift and fall of a buoyant body within a fluid to provide an electrical energy.

Abstract: A prechamber assembly for a combustion engine includes a prechamber component having one or more transfer ports, and a housing component having an igniter housing area. The prechamber component and the housing component are coupled together to at least partially define a prechamber. The housing component includes a first portion having a first material, and a second portion having a second material different from the first material, wherein the second portion is between the prechamber and the first portion.

Abstract: A device comprising a rigid substrate, a flexible cover element at least partially covering the substrate, a first structure formed in the substrate, adapted for accommodating liquids and adapted for releasing contents of one or more cells, spores, or viruses, the contents including the target molecules, a second structure formed in the substrate, adapted for accommodating liquids and comprising at least one binding member adapted for capturing the target molecules and for determining a value indicative for the presence and/or amount of the target molecules, a microfluidic network interconnecting at least the first structure and the second structure, and an actuator member adapted for effecting a fluid flow between the first structure and the second structure by pressing the flexible cover element against the substrate to selectively close a portion of the microfluidic network.

Abstract: Methods, apparatus, systems, and articles of manufacture to make and/or process a diagnostic test device are disclosed. An example apparatus includes a first portion including an opening; a second portion coupled to the first portion and house a lateral flow assay strip, the second portion including a first clip; and a push button located within the opening of the first portion, the push button moveable from a first position to a second position, the push button including a second clip to engage the first clip of the second portion to maintain the push button in the second position when moved into the second position.

Abstract: Methods, apparatus, systems, and articles of manufacture to make and/or process a diagnostic test device are disclosed. An example apparatus includes a sensor to measure a current between a first electrode and a second electrode of a bioelectrochemical cell coupled to a test zone corresponding to a target analyte on a porous media of a device; a processor to compare the current to a threshold; and when the current is more than the threshold, identify that the target analyte is present in a sample; and an antenna to wirelessly transmit results.

Abstract: Implementations include providing, by a deploy tool, clone data components in the first database system, each clone data component being a copy of a data component, defining, by the deploy tool, a source-side green access schema in the first database system, the green access schema providing views to the clone data components, providing, by a replication system and based on statements received from the deploy tool, consumer-side clone data components in the first database system, each consumer-side clone data component being a copy of a respective data component, defining, by a replication system and based on statements received from the deploy tool, a consumer-side green access schema in the first database system, the green access schema providing views to the source-side clone data components, and, during execution of the upgrade, replicating, by a handler of the replication system, data from at least one source-side data component to a consumer-side component.

Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative and/or quantitative detection of targets, including: introducing a sample containing targets into a reaction chamber formed between a first surface of the device and a second surface of a device, which is preferably located opposite to the first surface, wherein the distance between the first and the second surface is variable; and detecting the targets.

Abstract: The invention relates to a compound of formula (1) in free form or in pharmaceutically acceptable salt form to pharmaceutical compositions comprising said compound and to the use of said compound in the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva.

Abstract: The invention relates to a compound of formula (I) in free form or in pharmaceutically acceptable salt form to pharmaceutical compositions comprising said compound and to the use of said compound in the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva.

Abstract: The invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention relates to methods for determining the presence and/or amount of multiple nucleic acids in a sample.

Abstract: The invention relates to a compound of formula (I) in free form or in pharmaceutically acceptable salt form to pharmaceutical compositions comprising said compound and to the use of said compound in the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva.

Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The invention relates to a compound of formula (I) in free form or in pharmaceutically acceptable salt form (I) to pharmaceutical compositions comprising said compound and to the use of said compound in the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva.

Abstract: Implementations include providing, by a deploy tool, clone data components in the first database system, each clone data component being a copy of a data component, defining, by the deploy tool, a source-side green access schema in the first database system, the green access schema providing views to the clone data components, providing, by a replication system and based on statements received from the deploy tool, consumer-side clone data components in the first database system, each consumer-side clone data component being a copy of a respective data component, defining, by a replication system and based on statements received from the deploy tool, a consumer-side green access schema in the first database system, the green access schema providing views to the source-side clone data components, and, during execution of the upgrade, replicating, by a handler of the replication system, data from at least one source-side data component to a consumer-side component.