Abstract: A kinetic structural component may have a flexible structure having at least one degree of freedom. The flexible structure can be moved between a compressed position and an expanded position or vice versa. The flexible structure may have at least one substructure which is configured, when said flexible structure is in the expanded position, to expand to form a curve or an arc and/or linearly.

Abstract: In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject suffering from, or at risk for developing a thrombotic microangiopathy (TMA). The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2 inhibitory agent inhibits cellular injury associated with MASP-2-mediated alternative complement pathway activation, while leaving the classical (C1q-dependent) pathway component of the immune system intact.

Abstract: The present disclosure relates to a device for measuring a first analyte concentration and a second analyte concentration in a measuring medium, the device including: a sample cell; a first light source unit; a first detector unit; a functional element; a second light source unit; a second detector unit; and a control unit adapted to analyze a detected first light for determining a first value representing the concentration of the first analyte in the measuring medium and adapted to analyze a detected third light for determining a second value representing the concentration of the second analyte in the measuring medium. A method of using the device is also disclosed.

Abstract: A system that uses one or more artificial intelligence models that predict an effect of a predicted event on a current state of the system. For example, the model may predict how a rate of change in time-series data may be altered throughout the first time period based on the predicted event.

Abstract: The present disclosure is directed to a bioreactor or fermenter for the culturing of cells or microorganisms in suspension in a liquid medium in industrial scale comprising a vessel containing the culture in a liquid medium having a determined filling height; a stirrer provided in the vessel to stir the liquid medium; a first sparger arranged in the bottom portion of the vessel; and a second or optional more spargers provided above the first sparger to supply additional air bubbles and/or additional oxygen gas bubbles continuously to the liquid medium whereby the second sparger is located at a position in the bioreactor or fermenter above the first sparger in a predefined distance ?. It is also described a process for the independent management of dissolved CO2 and O2, by selecting a suitable modified gas flow rate qmod.

Abstract: Disclosed is a digital pH sensor for measuring the pH, comprising an electronics unit, sensor housing having a first half-cell and a second half-cell adapted to form a potential difference between the first electrode and the second electrode if the digital pH sensor is in contact with a measurement medium, wherein the electronics unit is adapted for converting the potential difference into a digital voltage value or a digital pH value, wherein the first electrolyte, the first electrode, the second electrolyte, and/or the second electrode are selected such that, at a pH value of 7 and a temperature of 25° C. in the measurement medium, the potential difference of the two electrodes is not equal to 0 mV, and wherein the electronics unit converts the potential difference into the digital measured pH value of 7 or a digital measured voltage value of 0 mV.

Abstract: In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2 inhibitory agent inhibits cellular injury associated with MASP-2-mediated alternative complement pathway activation, while leaving the classical (C1q-dependent) pathway component of the immune system intact.

Abstract: Aerial vehicles are assigned to routes within a transportation network based on a state of charge, state of power, and/or state of health for the aerial vehicle. Such aspects can be modeled based on one or more statistical models and/or machine-learned models, among other examples. As another example, an energy budget is used to ensure that the state of charge, state of power, and/or state of health of the aerial vehicle during and/or after traveling the route remains within the energy budget. A payload is assigned to a route and an associated aerial vehicle, thereby generating an itinerary. In examples, the itinerary is validated by the aerial vehicle to ensure that the aerial vehicle is capable of traveling the route with the payload. In examples where the aerial vehicle rejects the itinerary, the itinerary is assigned to another aerial vehicle and a new itinerary is identified for the aerial vehicle.

Abstract: A method for detecting liquid on a windowpane in which radiation is emitted by at least one radiation emitter, the radiation is coupled into the windowpane via at least one optical element, and, after reflection in the windowpane, the radiation is coupled out of the windowpane. The radiation which is coupled out of the windowpane is captured in single measurements. A measurement cycle is formed from a multiplicity of single measurements. An average value is calculated from the measurement results of a measurement cycle. The average value is used a reference value for the single measurements of the subsequent measurement cycle currently in progress. The differences between the measured values of the single measurements of a measurement cycle currently in progress and the reference value are determined. The differences between the measured values of the single measurements of the measurement cycle currently in progress and the reference value are evaluated statistically.

Abstract: The present disclosure relates to a pH-sensor for determining and/or monitoring a pH value of a medium, having a sensor unit with a wall in contact with the medium, and at least one pH-sensitive material, which has at least one spin state that changes as a function of a pH value. The at least one pH-sensitive material is arranged in or on a region of the wall in such a way that the at least one spin state is subjected to a change in the pH value of the medium. The pH-sensor also includes a spin-sensitive unit, which is configured to detect a variable associated with the at least one spin state, wherein the spin-sensitive unit is arranged in an environment of the at least one pH-sensitive material such that the spin-sensitive unit is subjected to a change in the spin state of the at least one pH-sensitive material.

Abstract: The present disclosure relates to a method of manufacturing an ion-selective sensor element for a potentiometric sensor, the sensor element having a sensor element body and at least one glass layer arranged on the sensor element body, the method comprising applying the at least one glass layer to the sensor element body by means of a thermal spraying method, in which a powder of glass particles is sprayed onto the sensor element body.

Abstract: The present disclosure relates to a sensor element for a potentiometric sensor, comprising a substrate formed from a metal alloy and an ion-selective enamel layer arranged on the substrate, wherein the metal alloy comprises at least one transition metal and wherein the ion-selective enamel layer contains a proportion of an oxide of the transition metal, and wherein an electrically conductive transition zone is arranged between the substrate and the enamel layer and contains the transition metal in a plurality of different oxidation states.

Abstract: A magnetic system for a medical implant system is described. A planar implant receiver coil is configured to lie underneath and parallel to overlying skin of an implanted patient for transcutaneous communication of an implant communications signal. A planar ring-shaped attachment magnet also is configured to lie underneath and parallel to the overlying skin and radially surrounds the receiver coil. The attachment magnet is characterized by a magnetic field configured to avoid creating torque on the attachment magnet in the presence of an external magnetic field.

Abstract: A magnet arrangement for an implantable medical device is described. An implant magnet has a modified disc shape and is capable of responding to an external magnetic field by rotating about a primary center rotation axis. The implant magnet shape has at least one cross-sectional view in which the cylindrical diameter corresponds to a horizontal coordinate axis, the center symmetry axis corresponds to a vertical coordinate axis, the height between the end surfaces is greatest at the center symmetry axis, and the height between the end surfaces progressively decreases from the center symmetry axis along the cylindrical diameter towards the outer circumference to define a secondary deflection angle with respect to the horizontal coordinate axis so that the implant magnet is capable of responding to the external magnetic field by deflecting within the secondary deflection angle about a secondary deflection axis defined by a cylinder diameter normal to the cross-sectional view.

Abstract: A sensor for measuring a pH value of a measuring liquid includes: a sensor element comprising a surface adapted to contact the measuring liquid; a radiation source configured to emit electromagnetic transmission radiation reaching the sensor element, wherein at least a portion of the transmission radiation is converted into measuring radiation by reflection and/or scattering in the region of the surface; a radiation receiver configured to receive the measuring radiation and convert it into electrical signals; and a measuring circuit connected to the radiation receiver and configured to determine a measured value representing the pH value of the measuring liquid from signals of the radiation receiver, wherein the surface adapted to contact the measuring liquid includes a pH-sensitive component and a SERS-active component.

Abstract: A sensor for measuring a pH value of a measuring liquid includes: a sensor element including a surface adapted to the measuring liquid; a radiation source configured to emit electromagnetic transmission radiation to the sensor element, wherein at least a portion of the transmission radiation is converted into measurement radiation by reflection and/or scattering in a region of the surface; a radiation receiver configured to receive the measurement radiation and convert it into electrical signals; and a measuring circuit configured to determine the pH value from signals, wherein a wavelength of at least a portion of the transmission radiation generates charge carriers in at least a surface region or a near-surface region of the surface of the sensor element as to effect a photoelectrochemical reaction with formation of hydrogen at the surface.

Abstract: The present disclosure relates to a device for measuring a first analyte concentration and a second analyte concentration in a measuring medium, the device including: a sample cell; a first light source unit; a first detector unit; a functional element; a second light source unit; a second detector unit; and a control unit adapted to analyze a detected first light for determining a first value representing the concentration of the first analyte in the measuring medium and adapted to analyze a detected third light for determining a second value representing the concentration of the second analyte in the measuring medium. A method of using the device is also disclosed.

Abstract: The present disclosure relates to a potentiometric probe for measuring a measured variable that represents an ion concentration in a measuring medium, including a probe base including a sensor circuit, and two electrochemical half-cells arranged such that one of the half-cells surrounds at least one portion of the other half-cell, wherein at least one of the half-cells is configured as a module which is connected to the probe base via a mechanical and electrical interface. In another embodiment, one of the half-cells is a measuring half-cell including an ion-selective membrane and a terminal lead which electrically contacts the ion-selective membrane. The other half-cell is a reference half-cell, wherein the measuring half-cell and/or the reference half-cell are each configured as a module which is connected to the probe base via a mechanical and electrical interface.

Abstract: Disclosed is a sensor arrangement on a process installation comprising at least two sensor tiles, wherein each sensor tile comprises a support and a plurality of sensors arranged on the support for determining a physical or chemical variable of a measuring medium, a process characteristic of the measuring medium, and/or a state of the process installation. A first sensor tile comprises a control unit having a transmit and receive module for data exchange with a control unit of a second sensor tile. The first control unit of the first sensor tile and/or a second control unit allocated to the sensor arrangement is designed to weight the values determined by each sensor tile. Weighting may be a function of the measured value variations of the sensor tile, the position of the sensor tile in the process installation, and/or the function of the sensor tile.

Abstract: The present disclosure relates to a pH-sensor for determining and/or monitoring a pH value of a medium, having a sensor unit with a wall in contact with the medium, and at least one pH-sensitive material, which has at least one spin state that changes as a function of a pH value. The at least one pH-sensitive material is arranged in or on a region of the wall in such a way that the at least one spin state is subjected to a change in the pH value of the medium. The pH-sensor also includes a spin-sensitive unit, which is configured to detect a variable associated with the at least one spin state, wherein the spin-sensitive unit is arranged in an environment of the at least one pH-sensitive material such that the spin-sensitive unit is subjected to a change in the spin state of the at least one pH-sensitive material.