Patents by Inventor Thomas Wilhelm

Thomas Wilhelm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9506893
    Abstract: A potentiometric probe, comprising: a housing, which has a first chamber, in which a reference half-cell is formed, which is in communication with a medium surrounding the housing via an electrolytic contact location arranged in a wall of the housing. The housing has a second chamber, in which a measuring half cell is formed, wherein the second chamber is closed on one end by a measuring membrane, such that a surface area of the measuring membrane facing away from the second chamber is in contact with the medium surrounding the housing, and wherein the measuring half cell has a lengthwise extension between the measuring membrane and a closure element bounding the measuring half cell on an end lying opposite the measuring membrane. A quotient of a separation of the measuring membrane from the closure element and an outer diameter of the housing amounts to less than 5, especially less than 2.
    Type: Grant
    Filed: June 20, 2011
    Date of Patent: November 29, 2016
    Assignee: Endress+l lauser Conducta GmbH+Co. KG
    Inventors: Thomas Wilhelm, Thilo Trapp
  • Publication number: 20160178564
    Abstract: The invention relates to an electrochemical half cell comprising: a housing, a potential sensing element, which is at least partially arranged within the housing and is electrically conductively connected to an electrical terminal pad arranged outside the housing; and an electrolyte that is solidified and arranged within the housing, wherein a plurality of gas bubbles which are in particular uniformly distributed within the volume occupied by the electrolyte, are trapped in the electrolyte.
    Type: Application
    Filed: December 16, 2015
    Publication date: June 23, 2016
    Inventors: Magdalena Losik, Thomas Wilhelm
  • Patent number: 9279781
    Abstract: A measuring arrangement for registering a measured variable representing concentration of an analyte in a measured medium, includes: a first electrode modified with a redox active substance, a second electrode, and a measuring circuit, which comprises a voltage source for applying at least one predetermined voltage between the first electrode and a reference, and an apparatus for registering electrical current flowing, in such case, between the first electrode and the second electrode or for registering a variable correlated with the electrical current flowing between the first electrode and the second electrode, wherein the second electrode is modified with the same redox active substance as the first electrode.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: March 8, 2016
    Assignee: ENDRESS + HAUSER CONDUCTA GESELLSCHAFT FUR MESS- UND REGELTECHNIK MBH + CO. KG
    Inventors: Thomas Wilhelm, Michael Hanko
  • Publication number: 20160060709
    Abstract: Methods for the diagnosis of leukemias, and more specifically AML, such as MLL-AF9 AML, in a subject, based on the assessment of the expression or activity of one or more of the genes listed in Tables 1 and 2 are disclosed. The use of antibodies or antigen-binding fragments thereof that bind to one or more of proteins showing preferential expression at the cell surface of AML leukemic cells for treating AML is also disclosed.
    Type: Application
    Filed: April 30, 2014
    Publication date: March 3, 2016
    Inventors: BRIAN THOMAS WILHELM, FREDERIC BARABE
  • Patent number: 9201039
    Abstract: A measuring transducer, which is embodied to produce and output a measurement signal dependent on the content of H+ and/or OH? ions present in a measured medium, wherein the measuring transducer has, in a region provided for contact with the measured medium, at least one polymer membrane selectively conducting H+ and/or OH? ions. The polymer membrane can comprise an H+ ion conducting polymer and/or an OH? ion conducting polymer.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: December 1, 2015
    Assignee: Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG
    Inventors: Michael Hanko, Thomas Wilhelm, Manfred Jagiella
  • Patent number: 9091642
    Abstract: A measuring transducer embodied to produce and output a measurement signal dependent on an activity of a target ion present in a measured medium, wherein the measuring transducer has, in a region provided for contact with the measured medium, at least one membrane conducting the target ion; wherein the measuring transducer has a first potential sensing element and a second potential sensing element, and wherein at least one section of the second potential sensing element is arranged in the interior of the membrane and the first potential sensing element is arranged in an inner electrolyte, which is separated from the measured medium by the membrane and is in contact with the membrane.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: July 28, 2015
    Assignee: Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG
    Inventors: Thomas Wilhelm, Michael Hanko, Stefan Wilke
  • Patent number: 9075036
    Abstract: A method for determining and/or monitoring at least one process variable of a medium by the utilization of at least of an electrochemical sensor comprising at least a first reference half cell and a second reference half cell, and comprising the method steps as follows: measuring a first electrical measured variable X1, cont with a first measuring period t1, meas and a first measuring interval t1, int with reference to the first reference half cell; measuring at least a second electrical measured variable X2, discont with a second measuring period t2, meas and a second measuring interval t2, int with reference to the second reference half cell; wherein the second measuring interval t2, int is greater than the first measuring interval t1, int; and determining the at least one process variable from at least one electrical measured variable X1, cont or X2, discont. Furthermore, the invention relates to an electrochemical sensor and to a system.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: July 7, 2015
    Assignee: Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG
    Inventors: Achim Gahr, Torsten Pechstein, Thomas Wilhelm
  • Publication number: 20150177182
    Abstract: A method for determining orthophosphate content of a liquid, comprising: registering a first measurement signal (ISE1) of an ion selective dihydrogen phosphate sensor; registering a second measurement signal (ISE2) of an ion selective hydrogen phosphate sensor; and determining the orthophosphate content of the liquid based on the first (ISE1) and second (ISE2) measurement signals. The dihydrogen phosphate sensor can comprise an ion selective dihydrogen phosphate electrode and the hydrogen phosphate sensor an ion selective hydrogen phosphate electrode. In the step of determining the orthophosphate content of the liquid, a cross-sensitivity of the dihydrogen phosphate electrode to hydrogen phosphate present in the liquid and a cross-sensitivity of the hydrogen phosphate electrode to dihydrogen phosphate present in the liquid can be taken into consideration.
    Type: Application
    Filed: December 16, 2014
    Publication date: June 25, 2015
    Inventors: Stefan Wilke, Thomas Wilhelm
  • Publication number: 20150053576
    Abstract: A measuring arrangement, comprising: at least three half-cells, each of which has a pH-sensitive membrane, and a measuring circuit, which is embodied to register a half-cell potential of each half-cell relative to a shared reference potential. The half-cell potential of each half-cell depends on the pH-value of a measured liquid contacting its pH-sensitive membrane. The sensitivity of a first of the three half-cells corresponds to a change of its half-cell potential relative to a change of the pH-value of the measured liquid causing it; the sensitivity of a second of the three half-cells corresponds to a change of its half-cell potential relative to a change of the pH-value of the measured liquid causing it; the sensitivity of a third of the three half-cells corresponds to a change of its half-cell potential relative to a change of the pH-value of the measured liquid causing it.
    Type: Application
    Filed: August 19, 2014
    Publication date: February 26, 2015
    Inventors: Torsten Pechstein, Thomas Wilhelm, Michael Hanko
  • Patent number: 8801371
    Abstract: A gas turbine including an inner casing and a rotor having rotatable blades with a shroud and a fin, and a cooling arrangement arranged in a cavity in the casing and about the rotatable blade. The blade shroud includes a protrusion extending away from the blade leading edge into the cavity and openings in the cavity wall for a cooling fluid. The protrusion is defined by angles in relation to the flow channel wall. The protrusion affects a vortex flow of cooling fluid entering through the openings and a vortex flow of hot gas entering from the flow channel into the cavity. The double-vortex formation reduces a mixing of the cooling flow with the hot gas flow and increases the efficiency of the cooling arrangement of the blade shroud and cavity walls.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: August 12, 2014
    Assignee: Alstom Technology Ltd.
    Inventors: Erich Kreiselmaier, Chiara Zambetti, Thomas Wilhelm
  • Patent number: 8764395
    Abstract: The blade for a gas turbine includes a blade airfoil having a leading edge and a trailing edge and extending in the blade longitudinal direction up to a blade tip, and at the blade tip the blade airfoil merges into a shroud segment, wherein on the shroud segment a first rib, projecting upwards, is arranged in the flow direction, extending transversely to the flow direction, and upstream of the first rib, in the region of the leading edge of the blade airfoil, a winglet is formed on the shroud segment for guiding of the hot gas flow in this region. With such a blade, a longer service life is achieved by provision being made for direct cooling of the winglet.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: July 1, 2014
    Assignee: Alstom Technology Ltd.
    Inventors: Thomas Wilhelm, Caroline Marchmont, Sergei Riazantsev
  • Patent number: 8753495
    Abstract: An electrochemical half cell for application in an electrochemical sensor, wherein a fill electrolyte of the half cell is in contact with an external medium via a liquid junction, characterized in that the liquid junction is controllable as regards its permeability and/or its flow.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: June 17, 2014
    Assignee: Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG
    Inventors: Stephan Buschnakowski, Lothar Auerswald, Thomas Wilhelm
  • Publication number: 20140144776
    Abstract: A potentiometric probe comprising: a housing, which has a first chamber, in which a reference half-cell is formed, which is in communication with a medium surrounding the housing via an electrolytic contact location arranged in a wall of the housing. The housing has a second chamber, in which a measuring half cell is formed, wherein the second chamber is closed on one end by a measuring membrane, such that a surface area of the measuring membrane facing away from the second chamber is in contact with the medium surrounding the housing, and wherein the measuring half cell has a lengthwise extension between the measuring membrane and a closure element bounding the measuring half cell on an end lying opposite the measuring membrane. A quotient of a separation of the measuring membrane from the closure element and an outer diameter of the housing amounts to less than 5, especially less than 2.
    Type: Application
    Filed: June 20, 2011
    Publication date: May 29, 2014
    Applicant: Endress + Hauser Conducta Gesellschaft fur Mess- und Regeltechnik mbH + Co. KG
    Inventors: Thomas Wilhelm, Thilo Trapp
  • Patent number: 8523526
    Abstract: A blade for a gas turbine, is provided and includes a blade airfoil which extends in a blade longitudinal direction and at the lower end merges into a shank which terminates in a blade root for fastening the blade on a blade carrier, particularly on a rotor disk. Devices for cooling the blade, which are supplied with a cooling medium, especially cooling air, via a feed hole arranged on the shank at the side, are arranged inside the blade airfoil. In the region of the feed hole provision is made for a planar stiffening element which reaches beyond the immediate region of the feed hole for reducing peaks of mechanical stress.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: September 3, 2013
    Assignee: Alstom Technology Ltd
    Inventors: Sergei Riazantsev, Thomas Wilhelm
  • Publication number: 20130213807
    Abstract: A measuring arrangement for registering an analyte concentration in a measured medium includes a three electrode arrangement having a working electrode, a reference electrode and a counter electrode. The working electrode includes an analyte-insensitive, redox mediator, and the reference electrode a pH-sensitive electrode. The counter electrode can be formed of an inert, electrically conductive material. The measuring arrangement can be embodied to provide a desired voltage between the working electrode and the reference electrode and to register the electrical current flowing, in such case, through the measured medium, between the counter electrode and the working electrode.
    Type: Application
    Filed: August 8, 2011
    Publication date: August 22, 2013
    Applicant: Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG
    Inventors: Michael Hanko, Thomas Wilhelm
  • Patent number: 8480528
    Abstract: A coaxial transmission, especially a hollow shaft drive, comprising a driving element (7) and a driven element (3), a plurality of radially mobile toothed quadrants (5) providing a gear ratio and transmitting a driving torque between the driving element (7) and the driven element (3). An internal gear (1) or especially the housing for receiving the inner gearing of the internal gear (13) are configured as a multipart structure.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: July 9, 2013
    Assignee: Wittenstein AG
    Inventors: Thomas Wilhelm, Michael Schmidt, Thomas Bayer
  • Publication number: 20130124562
    Abstract: Technologies are described herein for exporting content items from multiple disparate content sources to a single repository. Query parameters are received for locating content items hosted by one or more content servers of different types for export. Native search queries are generated for each content server from the query parameters and are executed on each content server. An export manifest listing the content items for export is built from query results received from the content servers. Each content item listed in the export manifest is then retrieved from the corresponding content server and stored in a single export repository.
    Type: Application
    Filed: November 10, 2011
    Publication date: May 16, 2013
    Applicant: Microsoft Corporation
    Inventors: Quentin Gary Christensen, Adam David Harmetz, Ryan Thomas Wilhelm, Julian Zbogar Smith, Yingtao Dong, John D. Fan, Thottam R. Sriram, Radhakrishnan Sundaresan, Anupama Janardhan, Graham Lee McMynn, Ramanathan Somasundaram, Jessica Anne Alspaugh, Bradley Stevenson
  • Publication number: 20130032479
    Abstract: A measuring transducer embodied to produce and output a measurement signal dependent on an activity of a target ion present in a measured medium, wherein the measuring transducer has, in a region provided for contact with the measured medium, at least one membrane conducting the target ion; wherein the measuring transducer has a first potential sensing element and a second potential sensing element, and wherein at least one section of the second potential sensing element is arranged in the interior of the membrane and the first potential sensing element is arranged in an inner electrolyte, which is separated from the measured medium by the membrane and is in contact with the membrane.
    Type: Application
    Filed: August 3, 2012
    Publication date: February 7, 2013
    Applicant: Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG
    Inventors: Michael Hanko, Thomas Wilhelm, Stefan Wilke
  • Publication number: 20120325659
    Abstract: A measuring transducer, which is embodied to produce and output a measurement signal dependent on the content of W and/or OH? ions present in a measured medium, wherein the measuring transducer has, in a region provided for contact with the measured medium, at least one polymer membrane selectively conducting W and/or OH? ions. The polymer membrane can comprise an W ion conducting polymer and/or an OH? ion conducting polymer.
    Type: Application
    Filed: June 22, 2012
    Publication date: December 27, 2012
    Applicant: Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG
    Inventors: Michael Hanko, Thomas Wilhelm, Manfred Jagiella
  • Patent number: 8307738
    Abstract: A coaxial transmission, especially a hollow shaft transmission for industrial drive engineering, having a high power density. The transmission comprises an input element (7), an element (3) and an output element, a drive torque being multiplied and transmitted between the input element (7) and the output element via a plurality of radially mobile toothed sections (5). At least one toothed section (5) has a bearing element (11) which is enlarged in its effective zone with respect to an input element (7).
    Type: Grant
    Filed: February 25, 2008
    Date of Patent: November 13, 2012
    Assignee: Wittenstein AG
    Inventors: Michael Schmidt, Thomas Wilhelm, Thomas Bayer