Patents by Inventor Tim Jones

Tim Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110094734
    Abstract: A means of investigating the quality and/or nature of perforations in a downhole environment is disclosed. A ‘pecking’ finger and depth measuring probe that can be axially and radially displaced enables the perforation to be located and its depth determined, through sequentially pecking around the wall lining in patterns such as radial, axial, and spiral sequences. By swinging a pecking finger that supports a depth measuring probe or cable with a bullet or conically shaped tip and measuring the displacement of the finger, the edge and centre of the hole can be determined with the largest displacement being when the tip is fully in the hole. When this position has been determined, the depth measuring cable is deployed and the depth of the perforation can be established by both an increase in the force required to push the cable and by the displacement of the pecking finger as it is pushed back by the reaction forces on the cable.
    Type: Application
    Filed: May 1, 2009
    Publication date: April 28, 2011
    Applicant: Advance Perforating Technologies Limited
    Inventors: Eric Atherton, Tim Jones
  • Patent number: 7931899
    Abstract: Humanized anti-A? antibodies derived from a murine antibody directed to a N-terminal epitope of A? are described. The humanized antibodies have reduced or no human T cell epitopes and bind A? with an affinity similar to that of the murine antibody.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: April 26, 2011
    Assignee: Medtronic, Inc
    Inventors: Lisa Lynn Shafer, Francis Joseph Carr, James Peter Gregson, Dawn Ann Bembridge, Tim Jones
  • Publication number: 20100294493
    Abstract: Methods and apparatus to change the mobility of formation fluids using thermal and non-thermal stimulation are described. An example apparatus to simultaneously provide thermal and non-thermal stimulation to change a mobility of a fluid in a subsurface formation includes one or more containers to hold one or more reactants. Additionally, the example apparatus includes a reactor to initiate a chemical reaction with at least one of the reactants. Further, the example apparatus includes an injector to inject a product of the chemical reaction into a formation. The product of the chemical reaction includes heat and a gaseous diluent to change a mobility of a fluid in a subsurface formation.
    Type: Application
    Filed: September 22, 2008
    Publication date: November 25, 2010
    Inventors: Anthony Robert Holmes Goodwin, Tim Jones, Keith James Massie, John Nighswander, Gary Tustin
  • Publication number: 20090300996
    Abstract: A system for reinforcing a tower is disclosed. The system includes a number of vertically elongated primary support risers. Each riser is attached to the tower at a series of spaced apart locations.
    Type: Application
    Filed: June 21, 2006
    Publication date: December 10, 2009
    Inventor: Tim Jones
  • Patent number: 7615615
    Abstract: The present invention relates a modified human interferon beta (INF?) which is less immunogenic than human INF? (SEQ ID NO: 1) when administered in vivo to a human. The modified human INF? comprises an amino acid residue sequence that differs from SEQ ID NO: 1 by an amino acid residue substitution selected from the group consisting of L57A, L57C, L57D L57E, L57G, L57H, L57K, L57N, L57P, L57Q, L57R, L57S, and L57T and an additional substitution selected from the group consisting of the H140A, H140C, H140G, and H140P.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: November 10, 2009
    Assignee: Merck Patent GmbH
    Inventors: Francis J. Carr, Graham Carter, Tim Jones, John Watkins, Matthew Baker
  • Publication number: 20090250794
    Abstract: In one embodiment, a semiconductor package is formed to include a leadframe that includes a plurality of die attach areas for attaching a semiconductor die to the leadframe. The leadframe is positioned to overlie another leadframe that forms some of the external terminals or leads of the package.
    Type: Application
    Filed: April 7, 2008
    Publication date: October 8, 2009
    Inventors: STEPHEN ST. GERMAIN, Roger M. Arbuthnot, Frank Tim Jones
  • Publication number: 20090187954
    Abstract: The described embodiments of the present invention provide a video database client application configured to execute on a wireless communication device or a device with a small display screen. The video database client application includes a user interface including user interface components designed to access video information and view videos using the wireless communication device. The video database client application includes a video player module to integrate and control a native video player within the user interface. The video database client application further includes a video database interface module adapted to retrieve videos and video information from the video database. The video database interface module functions to pre-fetch information from the video database based on anticipated user information needs.
    Type: Application
    Filed: January 23, 2008
    Publication date: July 23, 2009
    Inventors: Andreas Tuerk, Stephen Spence, Natalie Doduc, Karen Groenink, Matthew Sharifi, Tim Jones, Dwipal Desai
  • Publication number: 20090187859
    Abstract: The described embodiments of the present invention provide a video database client application configured to execute on a wireless communication device or a device with a small display screen. The video database client application includes a user interface including user interface components designed to access video information and view videos using the wireless communication device. The video database client application includes a video player module to integrate and control a native video player within the user interface. The video database client application further includes a video database interface module adapted to retrieve videos and video information from the video database. The video database interface module functions to pre-fetch information from the video database based on anticipated user information needs.
    Type: Application
    Filed: January 23, 2008
    Publication date: July 23, 2009
    Inventors: Andreas Tuerk, Stephen Spence, Natalie Doduc, Karen Groenink, Matthew Sharifi, Tim Jones, Dwipal Desai
  • Publication number: 20090175923
    Abstract: Humanized anti-A? antibodies derived from a murine antibody directed to a N-terminal epitope of A? are described. The humanized antibodies have reduced or no human T cell epitopes and bind A? with an affinity similar to that of the murine antibody.
    Type: Application
    Filed: November 26, 2008
    Publication date: July 9, 2009
    Applicant: MEDTRONIC, INC.
    Inventors: Lisa Lynn Shafer, Francis Joseph Carr, James Peter Gregson, Dawn Ann Bembridge, Tim Jones
  • Publication number: 20090043076
    Abstract: The present invention relates a modified human interferon beta (INF?) which is less immunogenic than human INF? (SEQ ID NO: 1) when administered in vivo to a human. The modified human INF? comprises an amino acid residue sequence that differs from SEQ ID NO: 1 by an amino acid residue substitution selected from the group consisting of L57A, L57C, L57D L57E, L57G, L57H, L57K, L57N, L57P, L57Q, L57R, L57S, and L57T and an additional substitution selected from the group consisting of the H140A, H140C, H140G, and H140P.
    Type: Application
    Filed: March 17, 2008
    Publication date: February 12, 2009
    Inventors: Francis J. Carr, Graham Carter, Tim Jones, John Watkins, Matthew Baker
  • Patent number: 7456257
    Abstract: The invention concerns human interferon alpha and in particular modified forms of interferon alpha 2 with improved properties. The improved proteins contain amino acid substitutions at specific positions that confer increased relative activity in biological assays. The invention provides also modified interferon alpha with improved biological activity concomitant with reduced immunogenic potential in the protein. The improved proteins are intended for therapeutic use in the treatment of diseases in humans.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: November 25, 2008
    Assignee: Merck Patent GmbH
    Inventors: Tim Jones, Matthew Baker, Marian Hanlon, Francis Joseph Carr
  • Patent number: 7430476
    Abstract: This invention relates to a novel approach for identification of T-cell epitopes, that give rise to an immune reaction in a living host. By means of this novel method biological compounds can be generated which have a no or at least a reduced immunogenicity when exposed to the immune system of a given species and compared with the relevant non-modified entity. Thus the invention relates also to novel biological molecules, especially proteins and antibodies, obtained by the method according to the invention.
    Type: Grant
    Filed: February 18, 2002
    Date of Patent: September 30, 2008
    Assignee: Merck Patent GmbH
    Inventors: Francis J. Carr, Graham Carter, Tim Jones, Stephen Williams, Anita Hamilton
  • Publication number: 20080196296
    Abstract: A fruit fly trap whose exterior shape represents a piece of fruit such as an apple, orange, banana or the like. The trap housing includes a bottom base portion and a top cover portion. The cover contains various holes through which fruit flies can gain access to the interior of the trap. The trap also includes a locking mechanism for securing the base and cover together. Located inside the trap is a natural product attractant stored within the interior of the trap. The construction of the trap is such that the liquid or powder attractant is retained inside the trap so it will not spill out. Also, a disabling adhesive is located on a glueboard insert and/or on the interior walls of the trap. Thus, when fruit flies enter the trap they will get caught in the adhesive or simply die because they cannot escape.
    Type: Application
    Filed: February 20, 2007
    Publication date: August 21, 2008
    Inventors: Bruce R. Studer, Tim Jones
  • Patent number: 7392141
    Abstract: A method of preparing a modified granulocyte colony stimulating factor (G-CSF) protein having reduced immunogenicity relative to human G-CSF comprises the steps of (i) identifying one or more potential T-cell epitopes within the amino acid sequence of human G-CSF (SEQ ID NO: 1); (ii) designing at least one sequence variant of at least one potential T-cell epitope identified in step (i), wherein the sequence variant eliminates or substantially reduces the MHC class II binding activity of the potential T-cell epitope; (iii) preparing, by recombinant DNA techniques, at least one modified G-CSF protein including a sequence variant designed in step (ii); (iv) evaluating at least one modified G-CSF protein prepared in step (iii) for G-CSF activity and immunogenicity; and (v) selecting a modified G-CSF protein evaluated in step (iv) that has substantially the same therapeutic G-CSF biological activity as, but substantially less immunogenicity than, human G-CSF.
    Type: Grant
    Filed: February 5, 2002
    Date of Patent: June 24, 2008
    Assignee: Merck Patent GmbH
    Inventors: Francis J. Carr, Graham Carter, Tim Jones, Stephen Williams
  • Patent number: 7381795
    Abstract: A modified interferon beta (INF?) is provided, which is less immunogenic than human INF? (SEQ ID NO: 1) when administered to a human in vivo. The modified INF? comprises an amino acid residue sequence that differs from SEQ ID NO: 1 by a substitution at one or more residues of SEQ ID NO: 1. Preferred substitutions are at residues selected from the group consisting of residue 50, 59, 60, 62, 63, 66, 67, 69, 70, 125, 126, 129, 130, 132, 133, and 138. Examples of suitable substitutions include F50A, L57A, I59A, Y60N, M62A, L63A, I66T, F67H, I69A, F70A, Y125A, Y126A, I129A, L130A, Y132S, L133A, Y138H, and Y138A.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: June 3, 2008
    Assignee: Merck Patent GmbH
    Inventors: Francis J. Carr, Graham Carter, Tim Jones, John Watkins, Matthew Baker
  • Publication number: 20070148739
    Abstract: The invention concerns human interferon alpha and in particular modified forms of interferon alpha 2 with improved properties. The improved proteins contain amino acid substitutions at specific positions that confer increased relative activity in biological assays. The invention provides also modified interferon alpha with improved biological activity concomitant with reduced immunogenic potential in the protein. The improved proteins are intended for therapeutic use in the treatment of diseases in humans.
    Type: Application
    Filed: February 18, 2004
    Publication date: June 28, 2007
    Inventors: Tim Jones, Matthew Baker, Marian Hanlon, Francis Carr
  • Patent number: 7135282
    Abstract: The present invention relates to the expression of peptides on viral particles, and more particularly to the expression of peptides on the interior or the viral capsid. Methods are described for modifying viruses so that exogenous epitopes are expressed on the interior of the viral capsid. Viruses that can be modified include (+) stranded RNA viruses, especially plant (+) stranded RNA viruses such as the cowpea mosaic virus. Internal expression is especially useful for the expression of hydrophobic epitopes. The modified viral particles also find use as vaccines and as such are capable of eliciting an immune response.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: November 14, 2006
    Assignee: The Dow Chemical Company
    Inventors: Koen Hellendoorn, Tim Jones
  • Patent number: D561865
    Type: Grant
    Filed: February 21, 2007
    Date of Patent: February 12, 2008
    Assignee: Gardner Manufacturing Company, Inc.
    Inventors: Bruce R. Studer, Tim Jones
  • Patent number: D564061
    Type: Grant
    Filed: February 20, 2007
    Date of Patent: March 11, 2008
    Assignee: Gardner Manufacturing Company, Inc.
    Inventors: Bruce R. Studer, Tim Jones
  • Patent number: D565145
    Type: Grant
    Filed: February 21, 2007
    Date of Patent: March 25, 2008
    Assignee: Gardner Manufacturing Company, Inc.
    Inventors: Bruce R. Studer, Tim Jones