Abstract: A device for radially compressing a stent may include a housing including a central opening and a first iris positioned adjacent the housing. The first iris includes a first circumferential ring and a first plurality of arms extending radially inward from the first circumferential ring to define a first central opening. The device may include a second iris axially offset from the first iris and including a second circumferential ring and a second plurality of arms extending radially inward from the second circumferential ring to define a second central opening. Rotation of the circumferential ring(s) relative to the housing changes a size of their respective central opening(s). The plurality of arms may shift between a first configuration and a second configuration via rotation of the circumferential ring(s) relative to the housing.

Abstract: A device for compressing a stent may include a housing extending along a central longitudinal axis, a first threaded member and a second threaded member, a first iris and a second iris, and a compressor element disposed between the second iris and the second threaded member. The first iris includes a first ring extending transverse to the axis and a first plurality of arms extending from the first ring parallel to the axis. The first plurality of arms defines a first central opening and rotation of the first threaded member changes a size of the first central opening. The second iris includes a second ring extending transverse to the axis and a second plurality of arms extending from the second ring parallel to the axis. The second plurality of arms defines a second central opening and rotation of the second threaded member changes a size of the second central opening.

Abstract: A location within a patient may be visualized while reducing potential impact on the patient's anatomy. A contrast media may be injected into a location within the patient's vasculature. The location may be viewed fluoroscopically. At least some of the injected contrast media may be recaptured in order to reduce a quantity of contrast media reaching the patient's anatomy.

Abstract: An improved guidewire may include an elongate shaft including a distal section and a proximal section extending proximally from the distal section. The elongate shaft includes a coiled portion disposed within the distal section. The coiled portion is curved in a first direction in a first plane. The elongate shaft includes a reverse curve portion curved in a second direction opposite the first direction. The reverse curve portion is disposed proximal of the coiled portion. A kit for forming the improved guidewire may include a guidewire having a coiled portion and a forming tool configured to form a reverse curve portion in the guidewire proximal of the coiled portion.

Abstract: Example medical devices including example cardiac pumps are disclosed. An example percutaneous circulatory support device system includes a blood pump including a pump housing having a distal end region and a proximal end region, a blood inlet positioned along the distal end region, a blood outlet positioned along the proximal end region and a first diaphragm pump positioned within the pump housing. Further, the first diaphragm pump is configured to draw blood into the pump inlet and pump blood out of the blood outlet.

Abstract: A delivery system for delivering a stent-valve may include an inner shaft including a distal tip, a stent-valve crimped onto the inner shaft, a distal sheath disposed over at least a lower portion of the stent-valve, and a proximal sheath disposed over at least an upper portion of the stent-valve. The distal sheath has a proximal free end with an angled proximal edge defining a short side and a long side of the distal sheath. The proximal sheath is actuatable independently from the distal sheath, and moveable proximally to release the upper portion of the stent-valve. The distal sheath is moveable distally to release the lower portion of the stent-valve. The angled proximal edge releases a first side of the lower portion of the stent-valve before an opposite second side.

Abstract: A mixing valve adapter is disclosed to connect water lines from a mixing valve to a sink faucet. An example of the mixing valve adapter includes an adapter body for connection between the mixing valve and the sink faucet. Valve connections of the adapter body connect to the respective water source connections and the mixing valve. Faucet connections on the adapter body connect to the sink faucet. The faucet connections have reinforcement structures. One of the valve connections also has a reinforcement structure. Connection housings connect the faucet connections to the sink faucet.

Abstract: A balloon catheter inflation device includes at least a first barrel, a first piston, and a second piston. The first barrel has a first end coupled to an outlet chamber with a nozzle, and a second open end. The first piston is slidable within the first barrel and has a first end configured to frictionally engage an inner surface of the first barrel. The first piston is configured to apply a first pressure to fluid within the first barrel and the outlet chamber. The second piston is configured to apply a second pressure to the outlet chamber, where the second pressure is higher than the first pressure.

Abstract: An outer sheath for delivering and re-sheathing an expandable balloon includes a tubular sheath having a distal end and a proximal end, and a plurality of balloon guide elements extending helically along an inner surface of a distal end region of the tubular sheath, where the plurality of balloon guide elements is spaced apart circumferentially. The outer sheath is part of a dilation balloon catheter assembly including a main catheter defining a lumen and a balloon catheter having a balloon fixed to a distal end thereof, where the balloon catheter is slidably disposed within the lumen of the main catheter, and the balloon is configured to move between a folded configuration and an expanded configuration. The plurality of balloon guide elements is configured to facilitate folding of the balloon after expansion when the balloon is pulled proximally into the outer sheath.

Abstract: A delivery system for delivering a stent-valve may include an inner shaft including a distal tip, a stent-valve crimped onto the inner shaft, a distal sheath disposed over at least a lower portion of the stent-valve, and a proximal sheath disposed over at least an upper portion of the stent-valve. The distal sheath has a proximal free end with an angled proximal edge defining a short side and a long side of the distal sheath. The proximal sheath is actuatable independently from the distal sheath, and moveable proximally to release the upper portion of the stent-valve. The distal sheath is moveable distally to release the lower portion of the stent-valve. The angled proximal edge releases a first side of the lower portion of the stent-valve before an opposite second side.

Abstract: A guidewire may be adapted for delivering a replacement heart valve implant as well as providing pacing to the heart as part of a process of implanting the replacement heart valve implant. The guidewire includes an elongate shaft including a distal section and a proximal section extending proximally from the distal section. The distal section forms a spiral portion that when unconstrained, includes a proximal spiral portion that curves in a direction and defines a plane and a distal spiral portion that extends out of the plane defined by the proximal spiral. One or more electrodes are disposed within the distal section for pacing.

Abstract: A rotation sleeve grip structure for garden hoses or other tubings is provided. A hose assembly can include a hose tubing and a rotation sleeve installed over an outer surface of the hose tubing, where the rotation sleeve is constrained between first and second open ends of the hose tubing and comprises a hollow cylindrical shell configured to enclose a portion of the hose tubing along a longitudinal length. The rotation sleeve is rotatable through 360 degrees about a circumference of the outer surface of the hose tubing. An inner sleeve can be affixed to the outer surface of the hose tubing, and may be disposed between the hose tubing and the rotation sleeve. One or more circumferential rib protrusions and corresponding circumferential channels for receiving the rib protrusions can be provided between the inner sleeve and the rotation sleeve.

Abstract: A rotation sleeve grip structure for garden hoses or other tubings is provided. A hose assembly can include a hose tubing and a rotation sleeve installed over an outer surface of the hose tubing, where the rotation sleeve is constrained between first and second open ends of the hose tubing and comprises a hollow cylindrical shell configured to enclose a portion of the hose tubing along a longitudinal length. The rotation sleeve is rotatable through 360 degrees about a circumference of the outer surface of the hose tubing. An inner sleeve can be affixed to the outer surface of the hose tubing, and may be disposed between the hose tubing and the rotation sleeve. One or more circumferential rib protrusions and corresponding circumferential channels for receiving the rib protrusions can be provided between the inner sleeve and the rotation sleeve.

Abstract: Example valve replacement devices and methods of using valve replacement devices are disclosed. An example device includes a framework including a plurality of strut members forming a proximal anchor region. The proximal anchor region includes a plurality of distal crowns and a first connector crown positioned along a distal end of the proximal anchor region. The device further includes a first commissure assembly coupled to the distal end, wherein the first commissure assembly includes a first commissure post, a first connector strut and a second connector strut. The device further includes one or more leaflets mounted at least partly within the framework. Further, the first and second connector struts each include a first end attached to the first commissure post and a second end attached to the first connector crown at a first pivot point. Further, the pivot point is positioned radially outward of the plurality of proximal crowns.

Abstract: An apparatus for loading a heart valve implant in an implant delivery system includes a stent crimping device including a central aperture and at least one radial compression mechanism, and a loading tube including a support structure attached to the loading tube and couplable to the crimping device. A method of loading the implant in the delivery system includes positioning the implant over the delivery system within the central aperture, compressing a distal portion of the implant, translating a distal sheath of the delivery system over the distal portion, translating the crimping device off the delivery system, sliding the loading tube over a proximal portion of the implant, translating the crimping device over the distal sheath and coupling the support structure to the crimping device, positioning a proximal sheath of the delivery system adjacent the crimping device, compressing the proximal portion, and translating the proximal sheath over the proximal portion.

Abstract: A radiopaque anchor and delivery device system may comprise a pigtail catheter and a radiopaque anchor. The pigtail catheter may be a dual lumen catheter configured to deploy the radiopaque anchor and delivery a radiopaque fluid or contrast agent. The implantable radiopaque anchor may be slidably disposed within and deployable from a lumen of the elongate shaft. A method for deploying an implantable radiopaque anchor may include advancing a pigtail catheter through the vasculature to a target location; identifying an implant location; forming a channel in a tissue at the implant location; and deploying an implantable radiopaque anchor within the channel.

Abstract: A crossing guidewire that is adapted for use in crossing an aortic valve may include a proximal shaft segment, a distal shaft segment including a distal end, and a hinge point disposed between the proximal shaft segment and the distal shaft segment. The hinge point may be adapted to allow the distal shaft segment to pivot relative to the proximal shaft segment when the distal end of the distal shaft segment contacts the aortic valve.

Abstract: System for cooled endocardial injection are disclosed. An example system may include a steerable catheter having a first lumen therein. The system may include a cooling circuit disposed along at least a portion of the steerable catheter, the cooling circuit having a fluid inlet, a fluid outlet, a proximal end, and a distal end. The cooling circuit may include a first lumen section extending distally along the steerable catheter and including the fluid inlet and a second lumen section extending proximally along the steerable catheter and including the fluid outlet. The system may include an injection catheter disposed in the first lumen. The injection catheter may be configured to deliver a cooled therapeutic fluid to endocardial tissue.

Abstract: A proximal loader may be used to facilitate loading a prosthetic valve into a catheter. A proximal load may include an elongate body releasably securable about a catheter, the elongate body including a first body half hingedly coupled with a second body half. Each of the first body half and the second body half includes an outer shell, a distal member segment disposed within the outer shell and defining half of a valve crimping region, and a proximal member segment slidingly disposed within the outer shell and defining half of a catheter accepting region.

Abstract: An aortic crossing catheter for directing a crossing wire through the aortic valve may include an outer sheath, an inner sheath slidably disposed within the outer sheath, and an expandable member at least partially fixed to the inner sheath and configured to move between a constrained delivery configuration to a radially expanded deployed configuration. Axial movement of the inner and outer sheaths relative one another radially expands the expandable member such that when a crossing wire is inserted through a lumen of the inner sheath, the wire is directed through the aortic valve.