Abstract: A method for determining immune competence against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) includes obtaining a blood sample from a subject in need thereof, detecting, in the blood sample, levels of binding antibodies against SARS-CoV-2 spike S1 protein and its receptor binding domain (RBD), and calculating a weighted value using a regression model. Another method for determining immune competence against SARS-CoV-2 is also disclosed.

Abstract: In one aspect, an integrated circuit includes a first conductive layer and a magnetoresistance element (MRE) disposed over and coupled to the first layer through first vias. The MRE is magnetized to produce a first magnetic orientation. The first layer is disposed over and coupled to a second conductive layer in the circuit through second vias. The circuit also includes a metal filler disposed proximate to the MRE. The metal filler is positioned over and coupled to the second layer through third vias. The circuit also includes a thermal dissipation path resulting from a physical input applied to the first MRE. The thermal dissipation path extends through the first through third vias, the first and second layers, an integrated circuit interconnection, and the metal filler.

Abstract: Semiconductor optoelectronic devices having a dilute nitride active layer are disclosed. In particular, the semiconductor devices have a dilute nitride active layer with a bandgap within a range from 0.7 eV and 1 eV. Photodetectors comprising a dilute nitride active layer have a responsivity of greater than 0.6 A/W at a wavelength of 1.3 ?m.

Abstract: A gate structure includes a gate dielectric layer, a work function layer, a metal layer, and a barrier layer. The work function layer is on the gate dielectric layer. The metal layer is over the work function layer. The barrier layer is sandwiched between the metal layer and the work function layer. The barrier layer includes silicon or aluminum.

Abstract: The present invention includes formulation comprising 2-(4-Methyl-[1,4]diazepan-1-yl)-5-oxo-5H-7-thia-1,11b-diaza-benzo[c]fluorene-6-carboxylic acid (5-methyl-pyrazin-2-ylmethyl)-amide (Compound I) or a pharmaceutically acceptable salt thereof for use in treating cancer.

Abstract: Provided is an injectable sustained release pharmaceutical formulation, including 3-acyl-naltrexone or a pharmaceutically acceptable salt thereof, a biocompatible organic solvent, and optionally a biocompatible polymeric material. Also provided is a method for treating opioid use disorder or alcoholism, including administering the injectable sustained release pharmaceutical formulation to a subject in need thereof. The pharmaceutical formulation provides a sustained release profile after one single injection, and the plasma levels of naltrexone in minipigs could provide a sustained release for 2 months.

Abstract: Disclosed is a method for delivering a gene into target cells, wherein immune cells are used as a vector for virus packaging and transportation to complete the delivery of biomacromolecules among cells, and thus change original characteristics of the target cells or generate new characteristics in the target cells. The gene delivery system, on one hand, can kill target cells such as tumor cells by utilizing the specificity of immune cells; and on the other hand, can modify genes of cells in a lesion by gene delivery to target cells, to directly kill the target cells.

Abstract: The application relates to the production of a soiled fabric, and more particularly to a method of manufacturing a standard carbon black soiled fabric for performance testing of washing machines. Water is adopted herein as the solvent to prepare a soil, which renders this method safe, environmentally friendly and economical. Moreover, this method introduces a fully-automatic continuous rolling-suction tentering and setting machine to control the pressure of the padder, the drying temperature, the air volume of the fan and the speed of chains, which reduces the manual intervention, achieving a highly-automatic printing and dyeing process. The reflectivity at four points on both sides of the standard carbon black soiled fabric according to the invention is 95% or more.

Abstract: A physiological monitoring system is provided. The physiological monitoring system includes a feature extraction device, an identifier, a processor, a physiological sensing device, and a vital-sign detector. The feature extraction device extracts biological information of an object to generate an extraction signal. The identifier receives the extraction signal and verifies an identity of the object according to the extraction signal. The processor receives the extraction signal and obtains at least one biological feature of the user according to the extraction signal. The physiological sensing device senses a physiological feature to generate a bio-signal. The vital-sign detector estimates vital-sign data of the object according to the bio-signal and the at least one biological feature.

Abstract: The present application provides an application of Chidamide in combination with R-CHOP in preparing a drug used for treating B-cell lymphoma, and also provides a drug comprising Chidamide and R-CHOP. Chidamide in combination with R-CHOP has a synergistic therapeutic effect on B-cell lymphoma.

Abstract: Disclosed are methods for producing steviol glycosides, such as rebaudioside D and rebaudioside M, using engineered yeast. The methods include at least two phases: first and second phases where a glucose-containing feed composition is provided to the medium in different modes of feeding in each phase, such as variable feeding and then constant feeding. The two phase feeding can result in a growth rate that is slower in the second phase than in the first phase, and consequently increased steviol glycoside production rates, reduced fermentation times, and reduced biomass concentrations.

Abstract: A physiological monitoring system is provided. The physiological monitoring system includes a feature extraction device, an identifier, a processor, a physiological sensing device, and a vital-sign detector. The feature extraction device extracts biological information of an object to generate an extraction signal. The identifier receives the extraction signal and verifies an identity of the object according to the extraction signal. The processor receives the extraction signal and obtains at least one biological feature of the user according to the extraction signal. The physiological sensing device senses a physiological feature to generate a bio-signal. The vital-sign detector estimates vital-sign data of the object according to the bio-signal and the at least one biological feature.

Abstract: Systems and methods for providing online content include evaluating a custom selection rule specified by a content provider. The custom selection rule may be used to control whether content from the provider is eligible for selection by a content selection service. The content selection rule may include one or more logical operators, a selected interest category and/or a selected list of one or more client identifiers.

Abstract: A semiconductor layer structure may include a substrate, a blocking layer disposed over the substrate, and one or more epitaxial layers disposed over the blocking layer. The blocking layer may have a thickness of between 50 nanometers (nm) and 4000 nm. The blocking layer may be configured to suppress defects from the substrate propagating to the one or more epitaxial layers. The one or more epitaxial layers may include a quantum-well layer that includes a quantum-well intermixing region formed using a high temperature treatment.

Abstract: A semiconductor package structure includes a semiconductor device with an active surface, a conductive pillar on the conductive pad, an adhesion strengthening layer, and an encapsulant in contact with the adhesion strengthening layer. The conductive pillar has a side surface and a top surface. The adhesion strengthening layer is conformally disposed on the side surface of the conductive pillar and the active surface of the semiconductor device.

Abstract: The present invention relates to a method of producing an article, comprising the step of producing the article by means of an additive manufacturing method from a build material comprising an aromatic polycarbonate and interference pigments and/or pearlescent pigments from the group of the metal oxide-coated micas. The invention likewise relates to an article obtainable by the method. The build material further comprises ?0.05% by weight to ?3% by weight of anhydride-modified ?-olefin polymer.

Abstract: An ESD protection circuit, an array substrate and a display device are disclosed. The ESD protection circuit includes a plurality of first ESD units, each of which includes: a first active layer a first insulating layer, a first metallic layer, a second insulating layer and a second metallic layer which are disposed on a base substrate; the first active layer includes a plurality of first connection terminals; the first metallic layer includes a plurality of first conductive terminals; the second metallic layer includes a plurality of second conductive terminals an orthographic projection of the first metallic layer and an orthographic projection of the second metallic layer the base substrate are at least partly overlapped with an orthographic projection of the first active layer on the base substrate respectively; and the first conductive terminals and the second conductive terminals are electrically connected with different first connection terminals, respectively.

Abstract: A screwdriver rotation structure includes a main body, a control member, a driving member, multiple first rolls, and multiple second rolls. The main body has multiple first recesses and multiple first pillars. Each of the first recesses has a first face. Each of the first pillars has two second faces, two third faces, and a first pivot portion. The main body has multiple second pivot portions. The control member has multiple third pivot portions and multiple second pillars. Each of the second pillars has a fourth face, a fifth face, and a fourth pivot portion. The control member has a fifth pivot portion and a mounting portion. Each of the first rolls is received in one of the first recesses. Each of the second rolls is received in one of the first recesses.

Abstract: The present disclosure provides a semiconductor device with a profiled work-function metal gate electrode. The semiconductor structure includes a metal gate structure formed in an opening of an insulating layer. The metal gate structure includes a gate dielectric layer, a barrier layer, a work-function metal layer between the gate dielectric layer and the barrier layer and a work-function adjustment layer over the barrier layer, wherein the work-function metal has an ordered grain orientation. The present disclosure also provides a method of making a semiconductor device with a profiled work-function metal gate electrode.

Abstract: An injectable pharmaceutical composition and a preparation method therefor. Specifically, the pharmaceutical composition comprises apixaban nanoparticles, a surface stabilizer, and may further comprise a sedimentation inhibitor. The pharmaceutical composition has good stability and is suitable for industrial mass production.