Patents by Inventor Ting Zhang

Ting Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200325156
    Abstract: The present invention relates to heteroaryl amide compounds, a preparation method therefor, pharmaceutical compositions thereof and applications thereof, and specifically, relates to a type of compounds having broad-spectrum tumor resistant activity, a preparation method therefor, pharmaceutical compositions containing the compounds, and uses of the compounds in the preparation of drugs for treating tumors.
    Type: Application
    Filed: November 2, 2018
    Publication date: October 15, 2020
    Applicants: Rui Jin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Xiamen University
    Inventors: Ruibao Ren, Xianming Deng, Min Wu, Ting Zhang, Bo Jiao, Qiaofeng Kang, Wei Huang
  • Patent number: 10799947
    Abstract: The present invention relates to a method of semi-solid indirect squeeze casting for Mg-based composite material, which aims at improving the mechanical property of the cast by adding magnesium zinc yttrium quasicrystal of high hardness, high elastic modulus and excellent matrix binding property acting as the reinforcement into the magnesium alloy matrix and manufacturing the cast through smelting using a vacuum atmosphere smelting furnace, agitating with ultrasonic wave assisted vibration in the rotating impeller jet agitation furnace and indirect squeeze casting against the problem of poor wettability, easy agglomeration, inhomogeneous distribution between the reinforcement particles and the matrix materials and poor properties of the manufactured cast. The manufacturing method of the present invention has advanced technologies and detailed and accurate data.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: October 13, 2020
    Assignee: NORTH UNIVERSITY OF CHINA
    Inventors: Yuhong Zhao, Liwen Chen, Ting Zhang, Jianquan Liang, Hua Hou, Feng Yan, Muxi Li
  • Patent number: 10799183
    Abstract: Various methods and systems are provided for scanning an image subject along a scan axis. The method includes stitching sectional datasets acquired from different anatomical sections of the image subject based on locations of a landmark in the sectional datasets.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: October 13, 2020
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Nan Cao, Yongchuan Lai, Shiyu Li, Ting Zhang
  • Publication number: 20200294327
    Abstract: The present disclosure generally relates to methods and systems for determining usage of a vehicle. A vehicle monitoring system may include, a memory, at least one processor coupled to the memory, and a sensory system that generates vehicle trip data during a monitoring window. The vehicle monitoring system may partition the trip data into a base group and a contrast group. The vehicle monitoring system may calculate a similarity score between the contrast group and the base group. The vehicle monitoring system may determine that the vehicle has been used for commercial purposes in response to the similarity score satisfying a threshold.
    Type: Application
    Filed: March 14, 2019
    Publication date: September 17, 2020
    Inventors: Kiyotaka KAWASHIMA, Ting Zhang
  • Publication number: 20200294328
    Abstract: The present disclosure generally relates to methods and systems for determining usage of a vehicle. A vehicle monitoring system may include a memory, at least one processor coupled to the memory, and a sensor system that generates vehicle trip data. The system may periodically determine a location of the vehicle during a trip while an ignition of the vehicle remains on. The system may determine that a duration of the trip is at least a threshold duration. The system may determine a direction of travel for segments between consecutive locations during the trip. The system may determine a ratio of a most common direction of travel for the trip to at least a second most common direction of travel for the trip. The system may determine that the vehicle has been used for commercial purposes in response to the ratio being less than a threshold ratio.
    Type: Application
    Filed: March 14, 2019
    Publication date: September 17, 2020
    Inventors: Kiyotaka KAWASHIMA, Ting ZHANG
  • Publication number: 20200276648
    Abstract: The invention relates to a method for preparing high-melting-point metal powder through multi-stage deep reduction, and belongs to the technical field of preparation of powder. The method includes the following steps of mixing dried high-melting-point metal oxide powder with magnesium powder and performing a self-propagating reaction, placing an intermediate product into a closed reaction kettle, leaching the intermediate product with hydrochloric acid as a leaching solution so as to obtain a low-valence oxide MexO precursor of the low-valence high-melting-point metal; uniformly mixing the precursor with calcium powder, pressing the mixture, placing the pressed mixture into a vacuum reduction furnace, heating the vacuum reduction furnace to 700-1200° C., performing deep reduction for 1-6 h, leaching a deep reduction product with hydrochloric acid as a leaching solution and performing treatment, so as to obtain the high-melting-point metal powder.
    Type: Application
    Filed: May 21, 2018
    Publication date: September 3, 2020
    Inventors: Ting an ZHANG, Zhihe DOU, Yan LIU, Zimu ZHANG, Guozhi LV, Qiuyue ZHAO, Liping NIU, Daxue FU, Weiguang ZHANG
  • Publication number: 20200270690
    Abstract: A serum/plasma LncRNA marker composition associated with auxiliary diagnosis of intrahepatic cholestasis of pregnancy and application thereof. The marker is selected from any one of ENST00000449605.1, ASO3480 and ENST00000505175.1. The serum/plasma LncRNA screening and auxiliary diagnosis kit is a LncRNAs diagnostic kit developed based on the specific serum/plasma LncRNA of ICP cases and healthy controls.
    Type: Application
    Filed: February 4, 2020
    Publication date: August 27, 2020
    Inventors: Ting ZHANG, Liang LUO, Jing WANG, Ruirui DONG, Ping ZOU, Shaohan ZOU, Rui YANG, Yao WANG, Na LI, Minjian CHEN, Xina MENG, Yan ZHANG, Conghua ZHOU
  • Patent number: 10757592
    Abstract: Systems and methods are described herein for analyzing the performance of a communications network (e.g., a mobile telecommunications network) using customer-centric and/or subscriber-centric data and information. In some embodiments, the systems and method may determine key performance indicators for a communications network by accessing call detail records from multiple communications network sources, generating a database of one or more customer stats table (CSTs) based on the accessed call records, wherein the CSTs include records for each individual customers of the communications network, and determining one or more key performance indicators (KPIs) for the overall network based on the records stored by the one or more customer stats tables.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: August 25, 2020
    Assignee: T-Mobile USA, Inc.
    Inventors: Le Roy Munar, Doris Ho, Ting Zhang
  • Publication number: 20200238566
    Abstract: An additive manufacturing apparatus utilizing combined electron beam selective melting and electron beam cutting. One electron beam emitting, focusing, and scanning device (6) is capable of emitting electron beams (67, 68) in three modes of heating, selective melting, and electron beam cutting. The electron beam in the heating mode is emitted to scan and preheat a powder bed (7). The electron beam (67) in the selective melting mode is emitted to scan and melt powder (71) in a section outline to form a section layer of a component. The electron beam (68) in the electron beam cutting mode is emitted to perform one or more cutting scans on inner and outer outlines (74, 75) of a section of the component to obtain accurate and smooth inner and outer outlines of the section. The heating, melting deposition, and outline cutting processes are repeated to obtain a required three-dimensional physical component.
    Type: Application
    Filed: January 17, 2018
    Publication date: July 30, 2020
    Inventors: Feng LIN, Bin ZHOU, Wentao YAN, Hongxin LI, Lei ZHANG, Ting ZHANG, Chao GUO
  • Publication number: 20200222398
    Abstract: Methods for treating various cancers by administering one or more compounds that target the dimeric protein survivin are disclosed. Pharmaceutical compositions containing such compounds are also disclosed, along with general methods of identifying anti-cancer compounds that target oncogenic dimeric proteins.
    Type: Application
    Filed: December 17, 2019
    Publication date: July 16, 2020
    Inventors: Jian-Ting Zhang, Liu Jing-Yuan
  • Publication number: 20200222285
    Abstract: A breast pump comprising: a container comprising a deformable body and a lid, the container further comprising an inlet and a vent, wherein the vent is provided with a vent valve which is configured to allow air flow out of the container through the vent but not into the container through the vent; a nipple shield for receiving milk expressed from a user's breast; and a flexible conduit fluidly connecting the nipple shield and the inlet of the deformable container, wherein, in use, milk expressed from the breast flows from the nipple shield through the conduit to the container.
    Type: Application
    Filed: February 20, 2019
    Publication date: July 16, 2020
    Inventor: Shu Ting Zhang
  • Publication number: 20200206808
    Abstract: The present invention relates to a method of semi-solid indirect squeeze casting for Mg-based composite material, which aims at improving the mechanical property of the cast by adding magnesium zinc yttrium quasicrystal of high hardness, high elastic modulus and excellent matrix binding property acting as the reinforcement into the magnesium alloy matrix and manufacturing the cast through smelting using a vacuum atmosphere smelting furnace, agitating with ultrasonic wave assisted vibration in the rotating impeller jet agitation furnace and indirect squeeze casting against the problem of poor wettability, easy agglomeration, inhomogeneous distribution between the reinforcement particles and the matrix materials and poor properties of the manufactured cast. The manufacturing method of the present invention has advanced technologies and detailed and accurate data.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 2, 2020
    Inventors: YUHONG ZHAO, LIWEN CHEN, TING ZHANG, JIANQUAN LIANG, HUA HOU, FENG YAN, MUXI LI
  • Publication number: 20200199081
    Abstract: Provided herein are compositions and methods for the treatment and prevention of cancer, including melanoma.
    Type: Application
    Filed: December 20, 2019
    Publication date: June 25, 2020
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, XIAMEN UNIVERSITY
    Inventors: Rutao CUI, Chengqian YIN, Xianming DENG, Ting ZHANG
  • Publication number: 20200191623
    Abstract: An intelligent sensing device and a sensing system are disclosed. The sensing device comprises a sensor unit provided with a plurality of sensors, and a wireless communication module, a memory module and a processing module connected with a data platform, wherein the processing module is connected with the sensor unit, the wireless communication module and the memory module; the processing module acquires the motion condition of a user by means of a preset detection algorithm according to a detection result of the acceleration sensor; and the sensing device has multiple different modes corresponding to different preset detection algorithms, and the user selects the preset detection algorithm by setting the mode of the sensing device. The sensing device is extremely low in power consumption, good in stability and sensitivity and high in storage capacity, can be interconnected with the data platform, and allows various sensors to be accessed thereto.
    Type: Application
    Filed: April 24, 2018
    Publication date: June 18, 2020
    Inventors: Yang LI, Mao WANG, Chang WANG, Ting ZHANG
  • Patent number: 10682332
    Abstract: Disclosed is a method of inhibiting growth of a melanoma cancer cell. The method includes contacting the melanoma cancer cell with an effective amount of a composition and the composition contains polymethoxyflavone. The polymethoxyflavone can be applied in an amount of 0.1 ?mol/L-1000 ?mol/L. A method of treating a subject having melanoma with the above discussed composition is also included.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: June 16, 2020
    Assignee: Huanggang Normal University
    Inventors: Shiming Li, Tao Long, Guliang Yang, Xiaojian Lv, Yin Xu, Ting Zhang
  • Publication number: 20200172521
    Abstract: The invention relates to the field of medicinal chemistry, and to five-membered-fused-six-membered aza-aromatic ring compound, preparation method thereof, pharmaceutical composition and application thereof. In particular, the invention relates to a type of compounds capable of specifically enhancing ubiquitination degradation of Ras proteins, a method for the preparation thereof, a pharmaceutical composition comprising the same, and use of these compounds in the manufacture of a medicament for preventing or treating a disease associated with Ras activity in vivo, in particular in the manufacture of a medicament for preventing or treating tumor growth and metastasis.
    Type: Application
    Filed: May 17, 2018
    Publication date: June 4, 2020
    Inventors: Xianming DENG, Hongrui WANG, Taoling ZHENG, Ting ZHANG, Tingting JIANG
  • Publication number: 20200165246
    Abstract: A type of substituted penta-fused hexa-heterocyclic compounds having selective inhibition for PIKfyve kinase, a pharmaceutically acceptable salt and pharmaceutically acceptable solvate thereof, a method for the preparation thereof, a pharmaceutical composition comprising the same, and use of these compounds in the manufacture of a medicament for preventing or treating a disease associated with PIKfyve in vivo, in particular in the manufacture of a medicament for preventing or treating tumor growth and metastasis.
    Type: Application
    Filed: August 3, 2018
    Publication date: May 28, 2020
    Applicant: Xiamen University
    Inventors: Xianming Deng, Wei Huang, Xihuan Sun, Ting Zhang, Zhixiang He, Yan Liu, Xinrui Wu, Baoding Zhang, Xiaoyang Li, Jingfang Zhang, Yun Chen, Li Li, Qingyan Xu, Zhiyu Hu
  • Publication number: 20200154083
    Abstract: A signal processing unit performs preprocessing, demosaic processing and color reproduction processing on an image signal. A control unit detects an image area having undergone a characteristic change exceeding a predetermined change amount, by using an image signal before the reproduction processing and an image signal after the color reproduction processing. The control unit associates area information indicating the detection result of the image area having undergone a characteristic change exceeding a predetermined change amount with the image signal after the color reproduction processing, and records the area information on a recording medium, or outputs the area information to an external device. Thus, it becomes possible to detect an image area where a control change caused by color reproduction processing is unnatural.
    Type: Application
    Filed: January 14, 2020
    Publication date: May 14, 2020
    Inventors: Ting Zhang, Yohei Myoga
  • Publication number: 20200138382
    Abstract: Various methods and systems are provided for scanning an image subject along a scan axis. The method includes stitching sectional datasets acquired from different anatomical sections of the image subject based on locations of a landmark in the sectional datasets.
    Type: Application
    Filed: November 7, 2018
    Publication date: May 7, 2020
    Inventors: Nan Cao, Yongchuan Lai, Shiyu Li, Ting Zhang
  • Publication number: 20200131167
    Abstract: Disclosed are compounds of Formula A, or a salt thereof: Formula (A), wherein: Het, Q and R1A to R4A are defined herein, which compounds have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating cough, itch, acute pain and neuropathic pain disorders using the same.
    Type: Application
    Filed: November 13, 2017
    Publication date: April 30, 2020
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Thomas J. Greshock, James Mulhearn, Anthony J. Roecker, Tianying Jian, Gang Zhou, Liangqin Guo, Walter Won, Ting Zhang, Rajan Anand, John E. Stelmach, Deping Wang, Ronald M. Kim, Mark E. Layton, Christopher S. Burgey, Philippe G. Nantermet