Abstract: Provided herein are compositions and methods for the treatment and prevention of cancer, including melanoma.

Abstract: A magnetic resonance (MR) imaging method of correcting phase errors is provided. The method includes applying, by an MR system, a pulse sequence to acquire the precorrection MR image. The method also includes acquiring, by the MR system, reference k-space data having a field of view (FOV) in a phase-encoding direction that is twice or more greater than an FOV of the precorrection MR image in the phase-encoding direction, wherein the reference k-space data and MR signals of the precorrection MR image are acquired with the same type of pulse sequences. The method further includes splitting the reference k-space data into first k-space data and second k-space data, generating a phase error map based on the first k-space data and the second k-space data, generating a phase-corrected image of the precorrection MR image based on the phase error map, and outputting the phase-corrected image.

Abstract: A power generation apparatus and a power system are provided. The power generation apparatus includes a first transportation means, a gas turbine and a generator, the first transportation means has a first platform, a first housing is provided on the first platform, the gas turbine is arranged in the first housing and has a first input terminal and a first output terminal, the generator is arranged in the first housing and has a second input terminal and a second output terminal, the first output terminal is connected with the second input terminal.

Abstract: Disclosed is a method for culturing urine-derived kidney stem cells, which belongs to the field of cell biology. The method comprises the following steps: isolating cells from the urine, and then culturing the cells with a culture medium of urine-derived kidney stem cells on feeder cells to obtain the urine-derived kidney stem cells, wherein the feeder cells are fibroblasts, and the culture medium of urine-derived kidney stem cells contains 200-300 mL of DMEM medium, 200-300 mL of F12 medium, 20-70 mL of fetal bovine serum, 0.2-2 mM of L-glutamine, 1-14 ng/mL of insulin, 0.1-1 ng/mL of epidermal growth factor, 5-30 ?g/mL of adenine, and 2-20 ?g/mL of hydrocortisone. By using the method, kidney stem cells with high proliferation capacity and specificity can be obtained and applied, and thus the regenerative outcome of the kidney tissue after injury can be improved.

Abstract: A system and method for providing point of interest related notifications within a vehicle that include receiving sensor data associated with an opening of at least one vehicle window of the vehicle. The system and method also include storing a first geo-location of the vehicle based on the sensor data and determining if a subsequent geo-location of the vehicle is within a predetermined vicinity of at least one point of interest. The system and method further include providing at least one point of interest related notification associated with the at least one point of interest if it is determined that the subsequent geo-location of the vehicle is within the predetermined vicinity of the at least one point of interest.

Abstract: Various aspects and embodiments disclosed herein relate generally to the modelling, treatment, reduction of resistance to the treatment, prevention, and/or diagnosis of diseases characterized by the formation of cancers. Embodiments include methods of treating cancer, comprising the steps of: providing a patient diagnosed with cancer with a therapeutic regime that includes at least one therapeutically effective dose of at least one agent that reduces the activity of at least one DNA damage/repair pathway. Other embodiments include methods of treating cancer, comprising the steps of: treating a patient diagnosed with cancer with a combination of therapeutic agents that includes at least one therapeutically effective anti-cancer agent and at least one compound that reduces the activity of at least one DNA damage/repair pathway.

Abstract: The present invention discloses a permanent packer and an extended gas lift method using the permanent packer, the method comprising: S1. imbedding the extended gas lift embedded pipe when setting the permanent packer, wherein the extended gas lift embedded pipe has an upper end being closed and a lower end being open, is provided therein with a one-way valve through which the fluid can pass from top to bottom; S2. lowering a breaking device from the production casing when in the extended gas lift, to break the upper end of the extended gas lift embedded pipe such that the upper and lower ends of the extended gas lift embedded pipe are communicated; and S3. injecting gas into the production casing, lifting the accumulated liquid in the bottom hole to the ground surface, to complete the extended gas lift.

Abstract: An additive manufacturing apparatus utilizing combined electron beam selective melting and electron beam cutting. One electron beam emitting, focusing, and scanning device (6) is capable of emitting electron beams (67, 68) in three modes of heating, selective melting, and electron beam cutting. The electron beam in the heating mode is emitted to scan and preheat a powder bed (7). The electron beam (67) in the selective melting mode is emitted to scan and melt powder (71) in a section outline to form a section layer of a component. The electron beam (68) in the electron beam cutting mode is emitted to perform one or more cutting scans on inner and outer outlines (74, 75) of a section of the component to obtain accurate and smooth inner and outer outlines of the section. The heating, melting deposition, and outline cutting processes are repeated to obtain a required three-dimensional physical component.

Abstract: The present invention discloses a system for providing mobile power, in which the required equipment for the power supply system at fracturing fields as well as connection cables and connection hoses are integrated properly, assigned onto three transport vehicles for movement and effectively connected. Intake components and a turbine generation system are combined on a first transport vehicle and installed together, then transported to customer sites directly, thus saving the installation time at the user sites. The two different designs on the locations of an exhaust stack and an exhaust silencer not only meet the requirements of road transportation, but also meet the requirements of exhaust gas emission during operations.

Abstract: A method for identifying prospective purchasers of battery electric vehicles (BEVs) may include defining a predetermined time frame associated with vehicle ownership, receiving a first dataset including a first subset of drivers are drivers who have owned or leased any first internal combustion engine (ICE) vehicle followed by any second ICE vehicle within the predetermined time frame, a second subset of drivers are drivers who have owned or leased any first ICE vehicle followed by any second BEV within the predetermined time frame, and a third subset of drivers are drivers who have not changed vehicles within the predetermined time frame, receiving a second dataset including a set of drivers who own or lease any first ICE vehicle which is in a same vehicle class as a target BEV, and identifying a target set of prospective purchasers of BEVs.

Abstract: An electronic device and a method for impactful parameter determination for brand enhancement is provided. The electronic device receives a plurality of responses for a plurality of questions associated with one or more surveys related to one or more services provided by an organization. The electronic device further determines a first set of responses for a first set of questions from the received plurality of responses. The electronic device further calculates an attribution score for each of the first set of parameters based on the determined first set of responses. The electronic device further determines a first parameter from the first set of parameters based on the calculated attribution scores. The determined first parameter, among the first set of parameters, has a maximum impact on a brand associated with the one or more services. The electronic device further controls a first service associated with the determined first parameter.

Abstract: The present invention discloses a system for providing mobile power, in which the required equipment for the power supply system at fracturing fields as well as connection cables and connection hoses are integrated properly, assigned onto three transport vehicles for movement and effectively connected. Intake components and a turbine generation system are combined on a first transport vehicle and installed together, then transported to customer sites directly, thus saving the installation time at the user sites. The two different designs on the locations of an exhaust stack and an exhaust silencer not only meet the requirements of road transportation, but also meet the requirements of exhaust gas emission during operations.

Abstract: The disclosed computer-implemented method may include (1) acquiring, via one or more biosensors, one or more biosignals generated by a user of a computing system, (2) using the one or more biosignals to anticipate a transition to or from a cognitive state of the user, and (3) providing a signal indicating the transition to or from the cognitive state of the user to an intelligent-facilitation subsystem adapted to perform one or more assistive actions to reduce the user's cognitive load. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The present invention discloses a system for providing mobile power, in which the required equipment for the power supply system at fracturing fields as well as connection cables and connection hoses are integrated properly, assigned onto three transport vehicles for movement and effectively connected. Intake components and a turbine generation system are combined on a first transport vehicle and installed together, then transported to customer sites directly, thus saving the installation time at the user sites. The two different designs on the locations of an exhaust stack and an exhaust silencer not only meet the requirements of road transportation, but also meet the requirements of exhaust gas emission during operations.

Abstract: Embodiments herein provide a vehicle-mounted gas turbine generator set, including: a chassis vehicle, a main cabin body and at least one of an air intake filter system, a ventilation filter system and an exhaust system. The chassis vehicle includes a main beam and an operator cabin. The operator cabin is located at a first side of the main beam in a first direction. The main cabin body defines a main accommodation space. A gas turbine and a generator connected with each other, and an electrical system connected with the gas turbine and the generator, are arranged in the main accommodation space. In a second direction perpendicular to the first direction, the main accommodation space is located between the main beam and the at least of the air intake filter system, the ventilation filter system and the exhaust system.

Abstract: This disclosure generally relates to power generation methods and systems based on gas turbine engines, and particularly to mobile and adaptive power generation systems and methods based on gas turbine engine for supplying mechanical and/or electrical power for fracturing operations at an oil wellsite. Various systems, platforms, components, devices, and methods are provided for flexibly and adaptively configure one of more gas turbines, hydraulic pumps, and electric generators to support both fracturing and electric demands at a well site. The disclosed implementations enable and facilitate a mobile, adaptive, and reconfigurable power system to provide both mechanical and electric power for hydraulic fracturing operation.