Patents by Inventor Tobias Werner

Tobias Werner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7401312
    Abstract: According to the present invention an automated method is provided for routing and designing an LSI (Large Scale Integrated Circuit). First, at least one generic of an instance of a book to be connected is located on the chip, wherein a generic of an instance is an area defined according to the measurements of said instance. Then, an initial route to said instance is generated by optimizing the route to the corresponding generic according to given design rules. Thereby, an optimized pin location is determined for said instance. Then, on the basis of said optimized pin location a layout for said instance is generated in place of the corresponding generic. Finally, the actually generated pin is connected with the corresponding end of the initial route.
    Type: Grant
    Filed: November 8, 2004
    Date of Patent: July 15, 2008
    Assignee: International Business Machines Corporation
    Inventors: Ulrich Krauch, Juergen Pille, Tobias Werner, Alexander Woerner
  • Publication number: 20050132319
    Abstract: According to the present invention an automated method is provided for routing and designing an LSI (Large Scale Integrated Circuit). First, at least one generic of an instance of a book to be connected is located on the chip, wherein a generic of an instance is an area defined according to the measurements of said instance. Then, an initial route to said instance is generated by optimizing the route to the corresponding generic according to given design rules. Thereby, an optimized pin location is determined for said instance. Then, on the basis of said optimized pin location a layout for said instance is generated in place of the corresponding generic. Finally, the actually generated pin is connected with the corresponding end of the initial route.
    Type: Application
    Filed: November 8, 2004
    Publication date: June 16, 2005
    Applicant: International Business Machines Corporation
    Inventors: Ulrich Krauch, Juergen Pille, Tobias Werner, Alexander Woerner
  • Patent number: 6835351
    Abstract: An optical-chemical sensor which is suitable for the continuous and discontinuous determination by luminescence optics of the concentration of chloride in an aqueous sample and which comprises a luminescence indicator (I) and a polymer (H) carrying the luminescence indicator (I) is characterized in that the luminescence indicator (I) is a non-lipophile acridine or bisacridine compound and the polymer (H) is a linear-chain hydrophile polymer soluble in an organic solvent, whereby it is possible to excite the sensor by commercially available LEDs, to manufacture very large numbers thereof at a moderate cost and in a reproducible way and, preferably, to use it for the determination of physiological chloride concentrations and the sensor furthermore has a wide dynamic measuring range for the determination of chloride; a high sensitivity, stability and reproducibility; a high selectivity for chloride; and a low pH cross-sensitivity.
    Type: Grant
    Filed: January 2, 2003
    Date of Patent: December 28, 2004
    Assignee: F. Hoffmann-La Roche AG
    Inventors: Christian Huber, Tobias Werner, Otto S. Wolfbeis, Douglas E. Bell, Susannah Young
  • Patent number: 6613282
    Abstract: An optical-chemical sensor which is suitable for the continuous and discontinuous determination by luminescence optics of the concentration of chloride in an aqueous sample and which comprises a luminescence indicator (I) and a polymer (H) carrying the luminescence indicator (I) is characterized in that the luminescence indicator (I) is a non-lipophile acridine or bisacridine compound and the polymer (H) is a linear-chain hydrophile polymer soluble in an organic solvent, whereby it is possible to excite the sensor by commercially available LEDs, to manufacture very large numbers thereof at a moderate cost and in a reproducible way and, preferably, to use it for the determination of physiological chloride concentrations and the sensor furthermore has a wide dynamic measuring range for the determination of chloride; a high sensitivity, stability and reproducibility; a high selectivity for chloride; and a low pH cross-sensitivity.
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: September 2, 2003
    Assignee: F. Hoffman-La Roche AG
    Inventors: Christian Huber, Tobias Werner, Otto S. Wolfbeis, Douglas E. Bell, Susannah Young
  • Publication number: 20030101803
    Abstract: An optical-chemical sensor which is suitable for the continuous and discontinuous determination by luminescence optics of the concentration of chloride in an aqueous sample and which comprises a luminescence indicator (I) and a polymer (H) carrying the luminescence indicator (I) is characterized in that the luminescence indicator (I) is a non-lipophile acridine or bisacridine compound and the polymer (H) is a linear-chain hydrophile polymer soluble in an organic solvent, whereby it is possible to excite the sensor by commercially available LEDs, to manufacture very large numbers thereof at a moderate cost and in a reproducible way and, preferably, to use it for the determination of physiological chloride concentrations and the sensor furthermore has a wide dynamic measuring range for the determination of chloride; a high sensitivity, stability and reproducibility; a high selectivity for chloride; and a low pH cross-sensitivity.
    Type: Application
    Filed: January 2, 2003
    Publication date: June 5, 2003
    Applicant: F. Hoffman-La Roche AG
    Inventors: Christian Huber, Tobias Werner, Otto S. Wolfbeis, Douglas E. Bell, Susannah Young
  • Publication number: 20020034826
    Abstract: An optical-chemical sensor which is suitable for the continuous and discontinuous determination by luminescence optics of the concentration of chloride in an aqueous sample and which comprises a luminescence indicator (I) and a polymer (H) carrying the luminescence indicator (I) is characterized in that the luminescence indicator (I) is a non-lipophile acridine or bisacridine compound and the polymer (H) is a linear-chain hydrophile polymer soluble in an organic solvent, whereby it is possible to excite the sensor by commercially available LEDs, to manufacture very large numbers thereof at a moderate cost and in a reproducible way and, preferably, to use it for the determination of physiological chloride concentrations and the sensor furthermore has a wide dynamic measuring range for the determination of chloride; a high sensitivity, stability and reproducibility; a high selectivity for chloride; and a low pH cross-sensitivity.
    Type: Application
    Filed: July 6, 2001
    Publication date: March 21, 2002
    Applicant: F. Hoffman-La Roche AG
    Inventors: Christian Huber, Tobias Werner, Otto S. Wolfbeis, Douglas E. Bell, Susannah Young
  • Patent number: 6046055
    Abstract: In a sensor layer for quantitative determination of at least one chemical component in a gaseous or liquid sample medium containing a chromophore which is directly or indirectly responsive to the component being determined by changing its absorption spectrum, and a luminophore which is not responsive to the component being determined, where there is an at least partial overlap between the emission spectrum of the luminophore and the absorption spectrum of the chromophore, and where the energy transfer between luminophore and chromophore produces a measurable change in at least one luminescence characteristic of the luminophore, the luminophore L and the chromophore .GAMMA. are ionic substances with differing electrical charges, which are incorporated in a matrix material that is permeable to the chemical component being determined.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: April 4, 2000
    Assignee: AVL Medical Instruments AG
    Inventors: Otto S. Wolfbeis, Tobias Werner, Ingo Klimant, Ute Kosch, Marco Jean-Pierre Leiner
  • Patent number: 6001999
    Abstract: The invention relates to a compound having the general Formula I in which one of the groups R.sub.1,R.sub.2,R.sub.3,R.sub.4,R.sub.5,R.sub.6 and R.sub.7 represents an ionophoric moiety and the remaining groups each independently are hydrogen, a lipophilic or hydrophilic group or a reactive group for coupling to a polymer or a biomolecule, or R.sub.2 forms an aromatic ring system together with R.sub.3 and R.sub.5 forms an aromatic ring system together with R.sub.6.the compound of the invention is useful as a luminescence indicator for cations.
    Type: Grant
    Filed: May 27, 1998
    Date of Patent: December 14, 1999
    Assignee: AVL Medical Instruments
    Inventors: Otto S. Wolfbeis, Jorg Daub, Thomas Gareis, Matthias Kollmannsberger, Stefan Heinl, Tobias Werner, Christian Huber, Andrei Boila-Gockel, Marco Jean Pierre Leiner
  • Patent number: 5981746
    Abstract: The invention relates to a compound having the general Formula I ##STR1## in which one of the groups R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 represents an ionophoric moiety and the remaining groups each independently are hydrogen, a lipophilic or hydrophilic group or a reactive group for coupling to a polymer or a biomolecule, or R.sub.2 forms an aromatic ring system together with R.sub.3 and R.sub.5 forms an aromatic ring system together with R.sub.6.The compound of the invention is useful as a luminescence indicator for alkali ions.
    Type: Grant
    Filed: May 27, 1998
    Date of Patent: November 9, 1999
    Assignee: AVL Medical Instruments
    Inventors: Otto S. Wolfbeis, Jorg Daub, Thomas Gareis, Matthias Kollmannsberger, Stefan Heinl, Tobias Werner, Christian Huber, Andrei Boila-Gockel, Marco Jean Pierre Leiner
  • Patent number: 5942189
    Abstract: In a sensor layer for quantitative determination of at least one chemical component in a gaseous or liquid sample medium containing a chromophore which is directly or indirectly responsive to the component being determined by changing its absorption spectrum, and a luminophore which is not responsive to the component being determined, where there is an at least partial overlap between the emission spectrum of the luminophore and the absorption spectrum of the chromophore, and where the energy transfer between luminophore and chromophore produces a measurable change in at least one luminescence characteristic of the luminophore, the luminophore L and the chromophore .GAMMA. are ionic substances with differing electrical charges, which are incorporated in a matrix material that is permeable to the chemical component being determined.
    Type: Grant
    Filed: October 14, 1997
    Date of Patent: August 24, 1999
    Assignee: AVL Medical Instruments AG
    Inventors: Otto S. Wolfbeis, Tobias Werner, Ingo Klimant, Ute Kosch, Marco Jean-Pierre Leiner