Abstract: The present application provides a method of manufacturing a. memory device having a word line (WL) with improved adhesion between a work function member and a conductive layer. The method includes steps of providing a semiconductor substrate defined with an active area and including an isolation structure surrounding the active area; forming a recess extending into the semiconductor substrate and across the active area; forming a first insulating layer conformal to the recess; disposing a first conductive material conformal to the first insulating layer; forming a conductive member surrounded by the first conductive material; disposing a second conductive material over the conductive member and removing a portion of the first conductive material above the second conductive material to form a conductive layer enclosing the conductive member; and forming a second insulating layer over the conductive layer and conformal to the first insulating layer.

Abstract: A supramolecular nano-drug based on irinotecan and niraparib, and a preparation method and application thereof are provided. The nano-drug is a stable supramolecular nanostructure with a regular geometric appearance, which is formed by self-assembling irinotecan and niraparib through supramolecular acting forces, such as hydrogen bonds, and hydrophobic Van Der Waals force by a dynamic supramolecular self-assembly method. The supramolecular nano-drug formed in the present disclosure is capable of significantly improving the sensitivity of colorectal cells to the irinotecan, and the quantity of DNA damages induced in the colorectal cells is significantly higher than that induced by the irinotecan as a single chemotherapeutic drug. The supramolecular nano-drug of the present disclosure can not only induce death of colorectal cancer cells in vitro, but also play a role in treating the colorectal cancer in vivo after being administrated intravenously.

Abstract: Methods and systems for optimizing an application for a computing system having multiple distinct memory locations that are interconnected by one or more communication channels include determining one or more data handling properties for a data region in an application. One or more data handling policies for the data region are determined based on the one or more data handling properties. Data setup costs are determined for a scope in the application that uses the data region in different memory locations based on the one or more data handling properties. The application is optimized in accordance with the one or more data handling policies and the data setup costs for the different memory locations.

Abstract: In an approach to protecting against out-of-bounds buffer references, an apparatus comprises one or more processor cores and a bounds-checking functional unit in each processor core configured to manage bounds information for one or more memory buffers. When a buffer is allocated, an address range of the buffer is stored. When a pointer is assigned an address within the address range of the buffer, the address range of the buffer is associated with the pointer. When the pointer is used to compute an address for an operation, whether the address for the operation is within the address range associated with the pointer is determined. If the address is not within the address range associated with the pointer, signaling that an error has occurred.

Abstract: An isolated antibody, comprising: a heavy chain variable domain (VH) that is at least 75% identical to the amino acid sequence of SEQ ID NO: 1; and a light chain variable domain (VL) that is at least 75% identical to the amino acid sequence of SEQ ID NO: 2; wherein the antibody binds specifically to human neurotensin receptor 1 (hNTSR1).

Abstract: A technique to cache content securely within edge network environments, even within portions of that network that might be considered less secure than what a customer desires, while still providing the acceleration and off-loading benefits of the edge network. The approach ensures that customer confidential data (whether content, keys, etc.) are not exposed either in transit or at rest. In this approach, only encrypted copies of the customer's content objects are maintained within the portion of the edge network, but without any need to manage the encryption keys. To take full advantage of the secure content caching technique, preferably the encrypted content (or portions thereof) are pre-positioned within the edge network portion to improve performance of secure content delivery from the environment.

Abstract: A technique to cache content securely within edge network environments, even within portions of that network that might be considered less secure than what a customer desires, while still providing the acceleration and off-loading benefits of the edge network. The approach ensures that customer confidential data (whether content, keys, etc.) are not exposed either in transit or at rest. In this approach, only encrypted copies of the customer's content objects are maintained within the portion of the edge network, but without any need to manage the encryption keys. To take full advantage of the secure content caching technique, preferably the encrypted content (or portions thereof) are pre-positioned within the edge network portion to improve performance of secure content delivery from the environment.

Abstract: The invention provides an optical engine module and a projector including the optical engine module. The optical engine module includes a casing, a light valve, a prism assembly and a fan assembly. The casing has an assembly port. The light valve is disposed at the assembly port and defines an accommodating space with the casing. The prism assembly is disposed in the accommodating space, and the light valve is configured to convert an illumination beam from the prism assembly into an image beam. The prism assembly includes a first region and a second region. The first region includes a light incident surface of the prism assembly, and a temperature of the second region is higher than a temperature of the first region. The fan assembly is disposed in the accommodating space. Airflow provided by the fan assembly circulates in the accommodating space.

Abstract: A optical communication system including a source device and an endpoint device. The source device include an array of laser diodes and is configured to drive the laser diodes to project a sequence of patterns into the field of view of the source device to define a set of serially-projected codes, each of which isolated to one respective angular division of the field of view of the source device. The endpoint device receives a serially-projected code from the source device which varies based which angular division of the field of view of the source device is occupied by the endpoint device.

Abstract: Pyrimidine compounds of Formula (I). Assignments to the variables in the formula are set forth herein. Also disclosed is a method of treating cancer with one of the pyrimidine compounds.

Abstract: An optical proximity sensor includes an optical path extender that extends an optical path length of the optical proximity sensor without a corresponding extension of a geometric path length of the optical proximity sensor. The optical path extender may be a high-refractive index material positioned along the optical path through the optical proximity sensor. The optical path extender may include one or more redirection features configured to change a direction of the light traveling within the optical proximity sensor. The optical path extender may include a photonic component configured to simulate an extension of the geometric path within an optical proximity sensor by applying a momentum-dependent transfer function to the light traveling through it.

Abstract: An audio data transmission method includes encapsulating, based on a physical layer frame header, a protocol data unit (PDU) including audio data, to obtain an audio data packet, where the physical layer frame header is modulated using a first digital modulation scheme, the PDU is modulated using a second digital modulation scheme, a value of a modulation rate of the first digital modulation scheme is equal to a value of a data transmission rate, and a value of a modulation rate of the second digital modulation scheme is less than the value of the data transmission rate, and sending the audio data packet on a BLUETOOTH low energy (BLE) physical channel at the data transmission rate.

Abstract: A method, system and apparatus for protecting from out of bounds memory references, including establishing a threshold number of active objects for examination for an out of bounds memory reference, determining whether a number of active objects for an application exceeds the threshold, and when the number of active objects exceeds the threshold, storing at least part of information about the active objects in an overflow table in a memory.

Abstract: Disclosed are methods for treatments of conditions involving CD47 upregulation using a compound of formula (I): Variables R1-R9, X, and Het are defined therein. Also disclosed are methods for increasing phagocytosis of a cell using such a compound and pharmaceutical compositions each containing the compound and an anti-cancer agent.

Abstract: Self-mixing interferometry (SMI) sensors can be used for generation of content using an input device without requiring a touch-sensitive surface. In some examples, the SMI sensors can be used to detect characteristics of the input device including position, orientation, and/or motion of the input device and/or force applied by the input device (e.g., force applied by a stylus tip). In some examples, some or all of the characteristics of the input device can be used in processing to generate content, including textual character input and three-dimensional objects. In some examples, the generation of content can use information from one or more additional sensors for the input device and/or from additional devices in combination with the characteristics of the input device based on the SMI sensors for generation of content.

Abstract: An optical sensing system includes a transmitter side and a receiver side, and is configured to be positioned below a display of an electronic device. The transmitter side includes a light emitter. The receiver side includes an array of photodiodes. The light emitter of the transmitter side and the array of photodiodes of the receiver side are optically coupled via a waveguide. As a result of this construction, the optical sensing system can be operated as an interferometric optical sensor.

Abstract: Self-mixing interferometry (SMI) sensors may include vertical cavity surface emitting lasers (VCSEL), photodetectors, and microelectromechanical systems (MEMS). The VCSEL, photodetectors, and MEMS may be vertically stacked. The MEMS may be moveable with respect to a VCSEL and may change a cavity length associated with the VCSEL. By changing the cavity length associated with the VCSEL, certain properties of emitted light may be changed, such as a wavelength value of the emitted light.

Abstract: An electronic device may include an infrared sensor with light sources and a quantum film photodetector. The light sources may emit short-wavelength infrared (SWIR) light through a display panel and the photodetector may receive the SWIR light through the panel after reflection off an object. The light sources and an integrated circuit may be mounted to a wall of a sensor module mounted to the panel. The module may include a lens. The photodetector may be disposed onto the rear wall, lens, integrated circuit, or display panel. The photodetector may include multiple types of quantum film to absorb different wavelengths of SWIR light. The SWIR light may pass through the display panel without distorting images emitted by the display panel. Using a quantum film in the photodetector may allow the photodetector to extend across a large surface area without unnecessarily increasing manufacturing cost for the device.

Abstract: A method, system and apparatus for protecting from out of bounds memory references, including establishing a threshold number of active objects for examination for an out of bounds memory reference, determining whether a number of active objects for an application exceeds the threshold, and when the number of active objects exceeds the threshold, storing at least part of information about the active objects in an overflow table in a memory.

Abstract: Configurations for a beam deflector metasurface are disclosed. The beam deflector metasurface may include beam deflectors arranged in a repeating, radial pattern of concentric zones. The beam deflector metasurface may be a large area, high numerical aperture metasurface optic with high efficiency when directing light at non-normal angles of incidence. The different concentric zones may direct received light in varying directions with various steepness of angles. The beam deflectors may include pillars that may be the same or different width, height, or shape. The pillars may function as diffractive gratings and the cross-coupling between the pillars may direct the output light. The zones of the beam deflector metasurface may allow for diffusing hot spots and spreading the light evenly over the target area. The beam deflector metasurface may be used for non-imaging applications where the deterioration of focus allows for better efficiency at non-normal input and output angles of incidence.