Abstract: Disclosed is a pharmaceutical nanoparticle containing a core and a shell coating the core. The core contains (3-{4-[2-({4-[3-(3-cyclohexylamino-propylamino)-propyl]-oxazol-2-ylmethyl}-amino)-6-methyl-pyrimidin-4-ylamino]-piperidin-1-yl}-3-oxo-propylamino)-acetic acid or a salt thereof, 1,2-dioleoyl-sn-glycero-3-phosphate, and an anionic polymer. The shell contains a lipid. Also disclosed is a method for preparing such as pharmaceutical nanoparticle. Further provided are a liposome containing a lipid bilayer enclosing an aqueous core and its preparation method.

Abstract: A head-mounted device may have a head-mounted support structure. Displays may present images to eye boxes at the rear of the head-mounted support structure. Cameras and other sensors may be supported by the head-mounted support structure. Tracking cameras may be used to track the movement of a user's hands or other external objects. In dim ambient lighting conditions, a supplemental illumination system may be activated to provide supplemental illumination for the tracking cameras. A single beam of supplemental illumination may be emitted over a given coverage area or a smaller beam of supplemental illumination may be steered across the given coverage area. Light-emitting devices such as infrared light-emitting diodes and infrared lasers may be used to form infrared light sources for the supplemental illumination system.

Abstract: An optical sensor module includes an interferometric sensor and a set of one or more optical elements. The interferometric sensor includes a coherent light source and at least one detector configured to generate an interferometric signal. The set of one or more optical elements is configured to simultaneously direct a first portion of light emitted by the coherent light source toward a first focus area within a first depth of focus; direct a second portion of the light emitted by the coherent light source toward a second focus area within a second depth of focus; and direct portions of the emitted light that are returned from one or more objects within the first depth of focus or the second depth of focus toward the interferometric sensor.

Abstract: An assembly method of an apparatus suitable for pressurized liquid transfusion is disclosed. In one step, a nozzle is to be inserted into the through hole of an elastomeric ring. Because the dimension of the nozzle is larger than the through hole, the internal wall of the elastomeric ring is tensioned and deformed so as to fit the nozzle. In one step, the elastomeric ring along with the nozzle is inserted into a receptacle. The dimension of the outer contour of the elastomeric ring needs to be decreased so as to be accommodated by the receptacle. Due to the flexibility of the elastomeric ring, it resumes at least partially to its original shape. Therefore, proper seal is created and maintained between the elastomeric ring and the nozzle such that leakage and pressure loss may be prevented. The foregoing is capable of working under high-pressured environment for prolonged use.

Abstract: A method of manufacturing a semiconductor device is provided. The method includes providing a semiconductor substrate having a trench. The method also includes forming a first buffer layer in the trench. The method further includes forming a doped-polysilicon layer on the first buffer layer in the trench. The method also includes performing a thermal treatment on the doped-polysilicon layer.

Abstract: A technique to cache content securely within edge network environments, even within portions of that network that might be considered less secure than what a customer desires, while still providing the acceleration and off-loading benefits of the edge network. The approach ensures that customer confidential data (whether content, keys, etc.) are not exposed either in transit or at rest. In this approach, only encrypted copies of the customer's content objects are maintained within the portion of the edge network, but without any need to manage the encryption keys. To take full advantage of the secure content caching technique, preferably the encrypted content (or portions thereof) are pre-positioned within the edge network portion to improve performance of secure content delivery from the environment.

Abstract: A semiconductor device and a method of manufacturing a semiconductor device are provided. The semiconductor device includes a semiconductor substrate and a word line structure. The semiconductor substrate has an active region. The word line structure is disposed in the active region of the semiconductor substrate. The word line structure includes a first work function layer, a second work function layer, and a buffer structure. The second work function layer is on the first work function layer. The buffer structure is between the first work function layer and the second work function layer.

Abstract: An electronic device includes an electromagnetic radiation source having an axis, a set of optics disposed about the axis, a reflector disposed about the axis non-symmetrically, and a controller configured to operate the electromagnetic radiation source while controlling a beam steering orientation (e.g., rotation) of the reflector. The reflector is disposed to reflect electromagnetic radiation emitted by the electromagnetic radiation source. The set of optics is disposed to shape electromagnetic radiation emitted by the electromagnetic radiation source and direct electromagnetic radiation received from the reflector into a panoramic field of view about the axis.

Abstract: Disclosed herein are electronic devices having touch input surfaces. A user's touch input or press on the touch input surface is detected using a set of lasers, such as vertical-cavity surface-emitting lasers (VCSELs) that emit beams of light toward the touch input surface. The user's touch causes changes in the self-mixing interference within the VCSEL of the emitted light with reflected light, such as from the touch input surface. Deflection and movement (e.g., drag motion) of the user's touch is determined from detected changes in the VCSELs' operation due to the self-mixing interference.

Abstract: An apparatus suitable for pressurized liquid transfusion is disclosed. The apparatus includes a nozzle assembly enclosed by the combination of a casing and a check nut. The nozzle assembly includes an elastomeric ring and a nozzle received by the combination of a cap and a receptacle. The elastomeric ring surrounds the nozzle and a proper seal is created therebetween. The dimension of the internal contour of the elastomeric ring is a bit smaller than the nozzle. The elastomeric ring is stretched so as to receive the nozzle. Additional processing may be applied to the elastomeric ring to achieve a different type of proper seal. Pressurized liquid passes through the apparatus so as to be transfused. The aforementioned seal serves to avoid leakage or pressure loss at the apparatus so as to avoid undesired aerosolization effects of an aerosolizer the apparatus is installed in.

Abstract: The present disclosure discloses a steel strip coiling temperature control method, a steel strip coiling temperature control device and a steel strip processing system, which relate to the technical field of steel strip production. The method comprises: seeking a corresponding speed compensation coefficient according to a target thickness of the steel strip and a target temperature parameter; seeking a corresponding speed gain coefficient from a second correspondence table according to a steel strip speed; correcting the steel strip speed based on the speed compensation coefficient and the speed gain coefficient to obtain a corrected steel strip speed; and adjusting a cooling efficiency of a laminar flow cooling apparatus according to the corrected steel strip speed.

Abstract: A optical communication system including a source device and an endpoint device. The source device include an array of laser diodes and is configured to drive the laser diodes to project a sequence of patterns into the field of view of the source device to define a set of serially-projected codes, each of which isolated to one respective angular division of the field of view of the source device. The endpoint device receives a serially-projected code from the source device which varies based which angular division of the field of view of the source device is occupied by the endpoint device.

Abstract: A user equipment, a base station, a joint training device for a user equipment and a base station, a joint channel estimation and feedback system for a user equipment and a base station, a feedback channel state information generation method, a channel matrix generation method, a joint training method, and a joint channel estimation and feedback method for a user equipment and a base station in wireless communication. Feedback channel state information is generated by a user equipment according to an actual pilot signal, and a deeper residual learning neural network is introduced into a base station to reconstruct a channel matrix of the base station according to the feedback channel state information. As such, it is possible that the base station can reconstruct a complete high-resolution channel matrix even if an actually received pilot signal is an incomplete low-resolution part.

Abstract: An electronic device may include a proximity sensor under a cover layer. The proximity sensor may include a light-emitter, such as an infrared light source, and a light-detector, such as an array of single-photon avalanche diodes (SPADs). The SPADs may measure light that has reflected from an external object. However, some of the light may be reflected by the cover layer, creating cross-talk. To distinguish between the cross-talk and signals from the external object, processing circuitry may histogram measurements from the SPADs. In particular, the processing circuitry may histogram near-field and/or far-field measurements into different histograms. The measurements may be weighted and/or gated prior to histogramming. In this way, cross-talk may be distinguished from the near-field and far-field signals.

Abstract: A LED driving system for driving a LED matrix. The LED driving system includes an interconnection structure having a first surface and a second surface opposite to the first surface and a plurality of driver dies/chips attached to the first surface of the interconnection structure. The LED matrix is divided into a plurality of sub LED matrix sections that are attached to the second surface of the interconnection structure. The interconnection structure is configured to electrically couple each one of the plurality of sub LED matrix sections to a corresponding one driver die/chip in the plurality of driver dies/chips.

Abstract: Methods and systems for optimizing an application for a computing system having multiple distinct memory locations that are interconnected by one or more communication channels include determining one or more data handling properties for a data region in an application. One or more data handling policies for the data region are determined based on the one or more data handling properties. Data setup costs are determined for a scope in the application that uses the data region in different memory locations based on the one or more data handling properties. The application is optimized in accordance with the one or more data handling policies and the data setup costs for the different memory locations.

Abstract: The present application provides a method of manufacturing a. memory device having a word line (WL) with improved adhesion between a work function member and a conductive layer. The method includes steps of providing a semiconductor substrate defined with an active area and including an isolation structure surrounding the active area; forming a recess extending into the semiconductor substrate and across the active area; forming a first insulating layer conformal to the recess; disposing a first conductive material conformal to the first insulating layer; forming a conductive member surrounded by the first conductive material; disposing a second conductive material over the conductive member and removing a portion of the first conductive material above the second conductive material to form a conductive layer enclosing the conductive member; and forming a second insulating layer over the conductive layer and conformal to the first insulating layer.

Abstract: The present application provides a memory device having a word line with an improved adhesion between a work function member and a conductive layer. The memory device includes a semiconductor substrate defined with an active area and including a recess extending into the semiconductor substrate, and a word line disposed within the recess, wherein the word line includes a first insulating layer disposed within and conformal to the recess, a conductive layer surrounded by the first insulating layer, a conductive member enclosed by the conductive layer, and a second insulating layer disposed over the conductive layer and conformal to the first insulating layer. A method of manufacturing the memory device is also disclosed.

Abstract: A supramolecular nano-drug based on irinotecan and niraparib, and a preparation method and application thereof are provided. The nano-drug is a stable supramolecular nanostructure with a regular geometric appearance, which is formed by self-assembling irinotecan and niraparib through supramolecular acting forces, such as hydrogen bonds, and hydrophobic Van Der Waals force by a dynamic supramolecular self-assembly method. The supramolecular nano-drug formed in the present disclosure is capable of significantly improving the sensitivity of colorectal cells to the irinotecan, and the quantity of DNA damages induced in the colorectal cells is significantly higher than that induced by the irinotecan as a single chemotherapeutic drug. The supramolecular nano-drug of the present disclosure can not only induce death of colorectal cancer cells in vitro, but also play a role in treating the colorectal cancer in vivo after being administrated intravenously.

Abstract: Methods and systems for optimizing an application for a computing system having multiple distinct memory locations that are interconnected by one or more communication channels include determining one or more data handling properties for a data region in an application. One or more data handling policies for the data region are determined based on the one or more data handling properties. Data setup costs are determined for a scope in the application that uses the data region in different memory locations based on the one or more data handling properties. The application is optimized in accordance with the one or more data handling policies and the data setup costs for the different memory locations.