Abstract: A computing system for fragment-based quantum mechanical calculation of protein properties is provided. A processor implements a protein fragmentation module that separates a computer-readable polypeptide sequence into a plurality of data units. For each subsequence of three adjacent amino acids in the polypeptide sequence, a first amino acid, a second amino acid, and a third amino acid are identified, each amino acid having a respective main chain including an amino group, a carbon, and a carboxyl group, and a side chain attached to the alpha carbon. The protein fragmentation module generates a data unit representing a first alpha carbon, a first carboxyl group, a second amino group, a second alpha carbon, a second carboxyl group, a second side chain, a third amino group, and a third alpha carbon, and stores the generated data unit in the memory.

Abstract: Compositions and methods for carboxymethylation of cytosine containing DNA and applications thereof for direct sequencing of 5mC are disclosed.

Abstract: A pilot transient protection method and system based on an oscillation frequency, and a device are provided, which relate to the field of line protection. An oscillating component and a power frequency component are separated in a short time window by determining an oscillating characteristic after a fault occurs in a line system, to distinguish the fault based on a relative relation between the oscillating component and the power frequency component and an energy magnitude of the power frequency component. A reliable action when an internal fault occurs is mostly achieved in case of ensuring no mal-operation when an external fault occurs. Therefore, a protection action speed can be effectively increased, and protection reliability is improved. In addition, a requirement for an algorithm is not high, engineering feasibility is very strong, and an application prospect is extensive.

Abstract: A method for assessing wind loads on trees based on point cloud models. This is achieved by performing semantic segmentation on images captured by unmanned aerial vehicles (UAVs), extracting images of the tree crowns for three-dimensional reconstruction, generating point cloud models, extracting point cloud data for both the crowns and trunks, and ultimately producing three-dimensional point cloud models for the target trees. Calculate the wind load impact area of tree crowns using the Alpha Shape algorithm. Combining wind speed, wind direction and tree geometric characteristics, simulate wind load distribution under varying wind direction and speed conditions using ANSYS Fluent software, and compute wind load results under applied wind loads. Finally, utilizing finite element analysis methods in conjunction with wind load data, structural stress analysis of trees is conducted to evaluate their fatigue lifespan and failure risk under wind loads.

Abstract: The present disclosure provides an annular anchor recycling instrument and an annular anchor recycling method, relating to the technical field of ocean engineering. The annular anchor recycling instrument includes a recycling tube, a pump body assembly, a lifting portion and an installation portion. One end of the recycling tube is provided with a cover body, and the other end of the recycling tube is configured to be an open end for cooperating with the top of the annular anchor. The pump body assembly is arranged on the cover body, and used to boost pressure to the interior of the recycling tube. The lifting portion is arranged on the cover body, and used to connect with a hoist. The installation portion are arranged on the cover body, and used to connect with the anchor chain on the annular anchor.

Abstract: This application provides a multiplexer, a radio frequency module, and an electronic device, which are used in the field of communication. The multiplexer includes: a first link, a second link, a third link, and a fourth link. The first link includes a first filter. The second link includes a second filter. Both the first link and the second link work on a first antenna through a first port. In a transmission slot of the first signal, the third link is connected to the first port, and the third link does not work. The fourth link sends the first signal through a second port, and the second port is different from the first port. In a receiving slot of the first signal, the third link works on the first antenna through the first port. The fourth link performs primary receiving of the first signal through the second port.

Abstract: Methods and systems provide for providing video-based chapter generation for a communication session. In one embodiment, the system receives a transcript and video content of a communication session between participants, the transcript including timestamps for a number of utterances associated with speaking participants; processes the video content to extract one or more pieces of textual content visible within the frames of the video content; segments frames of the video content into a number of contiguous topic segments; determines a title for each topic segment from one or more of: the transcript, and the extracted textual content; assigns a category label for each topic segment from a prespecified list of category labels; and transmits, to one or more client devices, the list of topic segments with determined title and assigned category label for each of the merged topic segments.

Abstract: The present application relates to the technical field of pharmaceutical chemistry, and particularly relates to compounds with ALK inhibitory activity and preparation method and use thereof. The compounds with ALK inhibitory activity provided by the present application are ALK inhibitors for treating diseases responsive to the inhibition of ALK kinase, can be used for treating ALK-positive diseases, such as tumors and cancers, and have broad application prospects.

Abstract: A detachable and sealed dehumidification cabinet includes a cabinet body and a sealing structure. The cabinet body is provided with a first main body. The first main body is provided with a first storage space. A plurality of first side walls are connected to surround and form the first storage space. The sealing structure is arranged at joints between the plurality of first side walls, and the sealing structure is configured for sealing the joints between the plurality of first side walls to form the sealed first storage space.

Abstract: The present disclosure relates to a control method for an energy storage converter. The method includes: determining a current fault component; determining a voltage fault component; determining a fault component of a positive-sequence current of the energy storage converter in a dq coordinate system of the new energy converter; determining a fault component of a current in a dq coordinate system of the energy storage converter; determining dq-axis currents of the energy storage converter according to the fault component of the current in the dq coordinate system of the energy storage converter and a pre-fault current of the energy storage converter; and controlling the energy storage converter to output current according to the dq-axis currents of the energy storage converter, so as to reduce an impact of the fault.

Abstract: A computer-implemented method includes storing threat intelligence documents and a graph data store. The graph data store includes entity nodes and a plurality of edges between the nodes extracted from the plurality of threat intelligence documents. Data is also stored linking the entity nodes and edges to the threat intelligence documents from which they were extracted. A generative machine learning model is employed to generate a summary text of threat intelligence for a first entity node, based on the first entity node, second entity nodes connected to the first entity node and the threat intelligence documents from which they were extracted. The summary text is inserted as a summary node into the graph comprising the generated summary text.

Abstract: Methods and systems provide for providing dynamic chapter generation for a communication session. In one embodiment, the system connects to a communication session with a number of participants; receives a transcript of a conversation between the participants produced during the communication session, the transcript including timestamps for a number of utterances associated with speaking participants; segments the utterances into a plurality of contiguous topic segments; generates a title for each topic segment, the generating comprising: labeling one or more of the topic segments based on one or more labeling rules, extracting one or more top phrases from each topic segment, determining a ranking of the top phrases for each topic segment, and generating the title for each topic segment based on the top ranked phrase for the topic segment; and transmits, to one or more client devices, a list of the topic segments with generated titles for the communication session.

Abstract: An adaptive integrated circuit (IC) testing method includes acquiring mass production data of a plurality of ICs, analyzing the mass production data by a training model for generating predicted data of the plurality of ICs, partitioning the plurality of ICs into at least two IC groups according to the predicted data, and adjusting at least two testing processes according to the at least two IC groups. The at least two IC groups are non-overlapped.

Abstract: Technology is disclosed for programmatically generating a summary by a language model of search results based on the corresponding relevance of the search results to an input search query to a search engine. A user inputs a search query into a search engine and the search engine determines and ranks a set of search results based on the relevance of each of the search results. A snippet of information is determined for the most relevant search results to the input search query. The snippets of information are used to generate an input prompt to a language model with an instruction to generate a summary of the snippets of information based on the input search query. The generated summary is provided in response to the user to the search query and/or is cached in order to provide the generated summary in response to similar search queries.

Abstract: A threat investigation agent performs investigative operations for autonomously investigating a potential cyber security threat. The investigative operations include preparing and transmitting inputs to a language model that include at least known threat event information pertaining to the potential cyber security threat, a function list describing functions that execute different types of investigative operation, and instructions directing a language model to return an output identifying a next investigative action that the language model selects as appropriate based on the known threat event information and the function list. The threat investigation agent discovers additional threat event information by executing the next investigative action in response to receiving the output from the language model, updating the known threat event information to include the additional threat event information, and repeating the investigative operations subsequent to updating the known threat event information.

Abstract: Provided is a self-leveling rotary handling-type multi-autonomous underwater vehicle (AUV) docking and transfer device and its method. The device includes a docking module, a vertical handling module, and a rotary handling module; the docking module includes a rotary platform with a guide frame, and a top surface of the rotary platform is provided with a first clamping device; the vertical handling module is mounted on a side of the docking module; the vertical handling module includes a liftable handling platform, and the handling platform is provided with a locking device and a second clamping device; the rotary handling module is mounted below the docking module; the rotary handling module includes a multi-branch rotating shaft and a horizontal plate mounted on each branch rotating shaft; and the horizontal plate is arranged with an AUV charging and information interaction device and a third clamping device.

Abstract: The wait time prediction technology determines expected wait times for businesses or other public services using a model generated based on at least historical wait times for the business. In response to a request from a user, an expected wait time for service at the business for at least one particular time period on a particular day of a week is determined using the model and provided for display. User feedback regarding the expected wait time may be requested, and used to refresh the model as new wait times and other information are collected.

Abstract: The present invention relates to camptothecin derivatives, their linker-payload conjugates, and antibody-drug conjugates, as well as pharmaceutically acceptable salts or esters, solvates, tautomers, stereoisomers, prodrugs, or isotopically labeled forms thereof, for use in the treatment or prevention of cancer. The invention further relates to a pharmaceutical composition comprising the camptothecin derivatives, their linker-payload conjugates, or antibody-drug conjugates; methods for the preparation of the same; and the use thereof.

Abstract: The apparatus includes transistors and a memory cell array. Memory cells located in a same column are coupled to a same transistor and a same word line, the transistors are coupled to a bit line, and memory cells located in a same row are coupled to a same plate line. The method includes turning on a transistor coupled to an unselected word line, applying a first voltage V1 to a bit line and applying a second voltage V2 to an unselected plate line, and using a selected word line, turning on a transistor coupled to the selected word line, applying a third voltage V3 to the bit line, and applying a fourth voltage V4 to a selected plate line, |V4?V3|=Vw, |V4?V1|<½Vw, |V3?V2|<½Vw.

Abstract: A secondary battery positive electrode material, relating to the field of battery materials. The secondary battery positive electrode material comprises large particles with particle size of ?2 ?m and small particles with particle size of ?1 ?m. The surfaces of some of the small particles are provided with a carbon coating layer; and the surfaces of some of the large particles are not provided with a carbon coating layer. According to the positive electrode material, by means of gradation design of the large and small particles, the compaction density is improved. Moreover, the surfaces of the small particles are coated with a carbon layer to provide sufficient electron transport paths. Additionally, the surfaces of the large particles are not hindered by a carbon coating layer, so that the impedance in a charge and discharge process can be reduced.