Abstract: The present disclosure relates to certain amides and heterocyclic compounds and uses of these amides and heterocyclic compounds to inhibit Rho-associated protein kinases and treat diseases including autoimmune disorders, graft versus host disease (GVHD), inflammation, cardiovascular disorders, central nervous system disorders, and neoplastic disorders.

Abstract: This invention relates to a wax composition comprising a plurality of fatty acid amide compounds having the Formula (I): where R1, R2, n1, n2, m1, and m2 are as described herein. This invention also relates to a wax composition comprising: a) one or more fatty acid amide compounds having the Formula (II): and b) one or more fatty acid amide compounds having the Formula (III): where R1, R2, n1, and n2 are as described herein. This invention also relates to a fatty acid amide compound having the Formula (I) and a process for preparing a compound of Formula (I).

Abstract: A decoder includes circuitry and memory coupled to the circuitry. The circuitry, in operation, generates a first coefficient value by applying a CCALF (cross component adaptive loop filtering) process to a first reconstructed image sample of a luma component, and clips the first coefficient value. The circuitry generates a second coefficient value by applying an ALF (adaptive loop filtering) process to a second reconstructed image sample of a chroma component, and clips the second coefficient value. The circuitry generates a third coefficient value by adding the clipped first coefficient value to the clipped second coefficient value, and decodes a third reconstructed image sample of the chroma component using the third coefficient value.

Abstract: A method, system, and storage device storing a computer program, for generating questions based on provided content, such as, for example, a document having words. The method comprises automatically estimating the probability of interesting phrases in the provided content, and generating a question in natural language based on the estimating. In one example embodiment herein, the estimating includes predicting the interesting phrases as answers, and the estimating is performed by a neural model. The method further comprises conditioning a question generation model based on the interesting phrases predicted in the predicting, the question generation model generating the question. The method also can include training the neural model. In one example, the method further comprises identifying start and end locations of the phrases in the provided content, and the identifying includes performing a dot product attention mechanism parameterizing a probability distribution.

Abstract: The present invention describes compositions, including pharmaceutical compositions, comprising a PD-1 axis binding antagonist, a CTLA4 antagonist, or a DNA demethylating agent and a benzamide compound and methods for use thereof, for example in the treatment of cancer. In some implementations, the methods for use including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer.

Abstract: A method and system for configuring regenerative braking energy recovery devices in urban rail transit provided by the present application, successively including the following steps: calculating a preliminarily configured capacity Pn of a regenerative braking energy recovery device predetermined for the traction substation n, then obtaining an optimally configured capacity Qn of the regenerative braking energy recovery devices; further, configuring the total number of the regenerative braking energy recovery devices; finally, configuring the type of the regenerative braking energy recovery devices. By reasonably configure the capacity and number of regenerative braking energy recovery devices in traction substations, the configuring method of the present application allows the regenerative braking energy generated by a train during braking to be completely absorbed, thus reduce the energy consumption of braking resistors.

Abstract: This invention relates to a wax composition comprising a plurality of fatty acid amide compounds having the Formula (I): where R1, R2, n1, n2, m1, and m2 are as described herein. This invention also relates to a wax composition comprising: a) one or more fatty acid amide compounds having the Formula (II): and b) one or more fatty acid amide compounds having the Formula (III): where R1, R2, n1, and n2 are as described herein. This invention also relates to a fatty acid amide compound having the Formula (I) and a process for preparing a compound of Formula (I).

Abstract: A file processing method is provided. A file conversion logic based on a player plug-in, a software development kit (SDK), and a recording plug-in that are loaded and run in a designated three-dimensional (3D) operation environment is obtained. A first to-be-processed file and a second to-be-processed file obtained based on a source file are played. Audio/video decoding is performed on each of the first to-be-processed file and the second to-be-processed file based on the file conversion logic. Distortion processing is performed on a result of the audio/video decoding, and a result of the distortion processing is stored in an image file format in a video random access memory (RAM).

Abstract: A power amplifier includes an output signal generator constructed to generate, on the basis of an input AC signal, an output signal including, in cycles, a first pulse being width higher in voltage than a first reference voltage and a second pulse being width lower in voltage than the first reference voltage and a feedback circuit constructed to generate a first bias signal corresponding to the output signal and feed back the first bias signal to an input side of the output signal generator to equalize a width of the first pulse and a width of the second pulse in the cycles of the output signal.

Abstract: A speaker box includes a housing having a receiving space; a sound generator having a diaphragm received in the receiving space for vibrating along a vibration direction; a sound aperture formed in the housing for communicating the sound generator with an outside of the speaker box; a dustproof member positioned by the housing and covering completely the sound aperture. The dustproof member includes a first dustproof element fixed to the housing and completely covering the sound aperture; a second dustproof element fixed to the housing; a gasket plate sandwiched between the first and second dustproof elements. The gasket forms a through hole aligned with the sound aperture and completely covered by the second dustproof element.

Abstract: A speaker assembly, includes: a housing with an accommodation space; a sound generator, and a sound aperture communicating the sound generator with an outside. A dustproof element is fixed by the housing and includes a first dustproof member, a pressing plate, and a second dustproof member attached to the pressing plate. The pressing plate includes a through hole aligned with the sound aperture, the through hole is completely covered by the second dustproof member. The housing includes at least two positioning protrusions located two sides of the sound aperture, and at least two melting posts extending along a protruding direction of the positioning protrusions. The pressing plate further includes two clip slots for engaging with the positioning protrusions. The positioning protrusion is located in the slip slot, and the pressing plate is fixed with the housing by the melted melting posts.

Abstract: The present invention is directed to certain amides and heterocyclic compounds. The present invention also relates to uses of these compounds to treat several diseases including autoimmune disorders, cardiovascular disorders, inflammation, central nervous system disorders, arterial thrombotic disorders, fibrotic disorders, glaucoma, and neoplastic disorders.

Abstract: Methods and systems including computer programs encoded on a computer storage medium, for utilizing equivalent linear velocity for first arrival picking of seismic refraction. In one aspect, a method includes receiving data for the shot gather record, generating a diving wave equation curve for a particular parameter pair of multiple parameter pairs, and integrating the shot gather record data corresponding to the diving wave equation curve over a selected range of offsets of the shot gather to generate an equivalent linear velocity value for the particular parameter pair and the shot gather record data, selecting, from the equivalent linear velocity values for the plurality of parameter pairs, a greatest equivalent linear velocity value of the equivalent linear velocity values, the greatest equivalent linear velocity value corresponding to a first-arrival parameter pair, and determining, using the first-arrival parameter pair, a set of first-arrival onsets for the selected sub-range of offsets.

Abstract: Techniques are described for generating seismic images based on pressure-shear (PS) wave information. Sensor data is generated by through seismic probing of an underground environment. The sensor data can include pressure (P) wave data. The sensor data is analyzed to determine PS wave data present in the sensor data. A CFP gathers spectrum is generated using the P wave velocity. An optimal curve through the CFP gathers spectrum is determined, and PS image(s) of the underground environment are generated by scanning along the optimal curve. The PS image(s) can be provided for presentation through interface(s). The generated PS wave images are correlated with P wave images, and can be plotted on the same coordinate system as P wave images.

Abstract: The present disclosure describes methods and systems, including computer-implemented methods, computer program products, and computer systems, for generating a velocity model and a density model for a subsurface region of a hydrocarbon reservoir. One method includes: receiving, by a data processing apparatus, a set of seismic data of the hydrocarbon reservoir; setting, by the data processing apparatus, an initial velocity model and an initial density model; generating, by the data processing apparatus, wavefields of the hydrocarbon reservoir based on the set of seismic data; selecting, by the data processing apparatus, a spatial direction; generating, by the data processing apparatus, a velocity gradient and a reflectivity gradient of the selected spatial direction based on the wavefields; and updating, by the data processing apparatus, the velocity model and the density model using the velocity gradient and the reflectivity gradient of the selected spatial direction.

Abstract: The present invention describes compositions, including pharmaceutical compositions, comprising an agent that binds members of the TNFRSF and a benzamide compound and methods for use thereof, for example in the treatment of cancer. In some implementations, the methods for use include methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer.

Abstract: The invention relates to a composite sandwich base panel for a Unit Load Device. The panel comprises an upper surface layer comprising fibre reinforcement material, a lower surface layer comprising fibre reinforcement material, and a central core section where at least the majority comprises a plurality of particles bound in a matrix material. The upper surface layer and lower surface layer are provided with a matrix material to bind them to the central core section.

Abstract: The invention belongs to the field of microbes and specifically relates to a myroides odoratimimus biocontrol strain for efficiently degrading aflatoxin and an application thereof. A myroides odoratimimus biocontrol strain 3J2MO is preserved at the China Center for Type Culture Collection (referred to as CCTCC) on Jun. 13, 2017 with preservation number CCTCC No. M 2017329. The myroides odoratimimus biocontrol strain of the invention can effectively degrade aflatoxin and may be configured to degrade aflatoxin and treat aflatoxin pollution of food crops.

Abstract: The present invention is directed to certain amides and heterocyclic compounds. The present invention also relates to uses of these compounds to treat several diseases including autoimmune disorders, cardiovascular disorders, inflammation, central nervous system disorders, arterial thrombotic disorders, fibrotic disorders, glaucoma, and neoplastic disorders.

Abstract: Implementations of the subject matter described herein provide a switching apparatus including an energy storage changement mechanism that can realize the main shaft energy storage and direction changement by using only one solenoid. Furthermore, the switching apparatus can be adopted in both two position ATS and three position ATS to satisfy different application scenarios or different market requirements. In addition, all transfers can be achieved by independent manual and electric operation, and each transfer action only requires powering a single solenoid.