Abstract: A single light emitting diode (LED) structure includes an array of spaced discrete light emitting zones separated by isolation areas. Each emitting zone includes an epitaxial structure configured to emit an emitting light having a particular wavelength over an effective emission area. In addition, the effective emission area for each emitting zone can be geometrically defined and electrically configured to provide a desired light intensity. For example, each effective emission area can have a selected size and spacing depending on the application and light intensity requirements. Each emitting zone also includes a wavelength conversion member on its effective emission area configured to convert an emitting wavelength of the emitting light to a different color. The single (LED) structure can include multiple colors at different zones to produce a desired spectra or design.

Abstract: Embodiments disclosed herein generally relate to identifying auto-fluorescent artifacts in a multiplexed immunofluorescent image. Particularly, aspects of the present disclosure are directed to accessing a multiplexed immunofluorescent image of a slice of specimen, wherein the multiplexed immunofluorescent image comprises one or more auto-fluorescent artifacts, processing the multiplexed immunofluorescent image using a machine-learning model, wherein an output of the processing corresponds to a prediction that the multiplexed immunofluorescent image includes one or more auto-fluorescent artifacts at one or more particular portions of the multiplexed immunofluorescent image, adjusting subsequent image processing based on the prediction, performing the subsequent image processing, and outputting a result of the subsequent image processing, wherein the result corresponds to a predicted characterization of the specimen.

Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for receiving user input indicating a first user selection of a first form of biometric authentication from a plurality of forms of biometric authentication, providing a first interface for display on a user device, the first interface corresponding to the first form, receiving first biometric data, the first biometric data being provided using the first interface, and selectively enabling communication between the user device and a back-end system based on the first biometric data.

Abstract: Systems and methods for item recommendation are described. Embodiments of the present disclosure receive input indicating a relationship between a user and a first content item; generate a knowledge graph based on the input, wherein the knowledge graph comprises relationship information between the user and a plurality of content items; generate a first feature embedding representing the user and a second feature embedding representing a second content item of the plurality of content items based on the knowledge graph, wherein the second feature embedding is generated using a first modality for a query vector of an attention mechanism and a second modality for a key vector and a value vector of the attention mechanism; compare the first feature embedding to the second feature embedding to obtain a similarity score; and recommend the second content item for the user based on the similarity score.

Abstract: Techniques and systems are provided for predicting answers in response to one or more input queries. For instance, text from a corpus of text can be processed by a reader to generate one or multiple question and answer spaces. A question and answer space can include answerable questions and the answers associated with the questions (referred to as “question and answer pairs”). A query defining a question can be received (e.g., from a user input device) and processed by a retriever portion of the system. The retriever portion of the system can retrieve an answer to the question from the one or more pre-constructed question and answer spaces, and/or can determine an answer by comparing one or more answers retrieved from the one or more pre-constructed question and answer spaces to an answer generated by a retriever-reader system.

Abstract: An object of the present invention is to provide novel mesenchymal stem cells demonstrating superior therapeutic effects against various diseases, a novel pharmaceutical composition containing these mesenchymal stem cells, and a method for preparing the same. The present invention relates to ROR1-positive mesenchymal stem cells. The ROR1-positive mesenchymal stem cells are preferably positive for CD29, CD73, CD90, CD105 and CD166 and are derived from umbilical cord or adipose tissue.

Abstract: Disclosed are compounds of formulae I and II, and pharmaceutically acceptable salts and prodrugs thereof, which are inhibitors of the complement system. Also provided are pharmaceutical compositions comprising such a compound, and methods of using the compounds and compositions in the treatment or prevention of a disease or condition characterized by aberrant complement system activity.

Abstract: Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, the catheter can be anchored to a superior surface of a mitral valve leaflet and a leaflet anchor can be advanced into the mitral valve leaflet to secure the mitral valve leaflet to a leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

Abstract: The invention proposed damper protection for direct drive motor angle limits This mechanism includes main components: Assembly guideway-spring, and Assembly angle limit bar, and Assembly direct-drive motor. The content mentioned in the invention describes the damping spring integrated inside the direct motor to protect the device when operating within the desired stroke limit It can be applied to high-precision devices and motors. The invention's products can be applied in Direct-drive motor mechanisms that limit rotation angle with high-accuracy such as robotic arms, multi-sensor automatic observation devices, or unmanned equipment.

Abstract: Methods and devices for transvascular prosthetic chordae tendinae implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, the catheter can be anchored to a superior surface of a mitral valve leaflet and a leaflet anchor can be advanced into the mitral valve leaflet to secure the mitral valve leaflet to a leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

Abstract: A virtual camera captures first images of a three-dimensional (3D) digital representation of a visual asset from different perspectives and under different lighting conditions. The first images are training images that are stored in a memory. One or more processors implement a generative adversarial network (GAN) that includes a generator and a discriminator, which are implemented as different neural networks. The generator generates second images that represent variations of the visual asset concurrently with the discriminator attempting to distinguish between the first and second images. The one or more processors update a first model in the discriminator and/or a second model in the generator based on whether the discriminator successfully distinguished between the first and second images. Once trained, the generator generates images of the visual asset based on the first model, e.g., based on a label or an outline of the visual asset.

Abstract: Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, a leaflet connector carried by a distal end of the catheter can be anchored to a superior surface of a mitral valve leaflet. A needle is axially advanceable through the leaflet connector and through the leaflet. A leaflet anchor having a leaflet suture can be advanced out of the needle to secure the mitral valve leaflet to the leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

Abstract: The present invention provides a method of fraud detection in telecommunication including 4 steps: collecting user-profiling data, analyzing encrypted text messages, extracting features, building fraudulent subscribers classification model, developing keyword rule to detect fraudulent subscribers, proposing multiple options to prevent fraudulent subscribers in realtime.

Abstract: A computer-implemented method is disclosed for determining one or more characteristics of a dialog between a computer system and user. The method may comprise receiving a system utterance comprising one or more tokens defining one or more words generated by the computer system; receiving a user utterance comprising one or more tokens defining one or more words uttered by a user in response to the system utterance, the system utterance and the user utterance forming a dialog context; receiving one or more utterance candidates comprising one or more tokens; for each utterance candidate, generating an input sequence combining the one or more tokens of each of the system utterance, the user utterance, and the utterance candidate; and for each utterance candidate, evaluating the generated input sequence with a model to determine a probability that the utterance candidate is relevant to the dialog context.

Abstract: A retaining ring can be shaped by machining or lapping the bottom surface of the ring to form a shaped profile in the bottom surface. The bottom surface of the retaining ring can include flat, sloped and curved portions. The lapping can be performed using a machine that dedicated for use in lapping the bottom surface of retaining rings. During the lapping the ring can be permitted to rotate freely about an axis of the ring. The bottom surface of the retaining ring can have curved or flat portions.

Abstract: Digital content interaction prediction and training techniques that address imbalanced classes are described. In one or more implementations, a digital medium environment is described to predict user interaction with digital content that addresses an imbalance of numbers included in first and second classes in training data used to train a model using machine learning. The training data is received that describes the first class and the second class. A model is trained using machine learning. The training includes sampling the training data to include at least one subset of the training data from the first class and at least one subset of the training data from the second class. Iterative selections are made of a batch from the sampled training data. The iteratively selected batches are iteratively processed by a classifier implemented using machine learning to train the model.

Abstract: A method for tracing an error of a logic system design includes obtaining an assertion failure of a combinational cone of the logic system design, the combinational cone including a plurality of sub-cones; and obtaining machine learning models of the sub-cones. Each sub-cone represents a sub-circuitry of the logic system design and has one or more input signals and an output signal. The assertion failure indicates an actual signal value of the combinational cone at a current clock cycle being different from an expected output value at the current clock cycle. The method also includes: performing backtracing on the sub-cones according to the assertion failure, the machine learning models of the sub-cones, and dynamic backtracing sensitivities corresponding to the sub-cones, to obtain a backtracing result; and outputting one or more target sub-cones as candidate root causes of the assertion failure according to the backtracing result.

Abstract: A packaged LED device comprising: a pad-extended LED chip comprising: at least one LED chip having a substrate, a first semiconductor layer, an active layer and a second semiconductor layer; a first pad electrically connected to the first type semiconductor layer and a second pad electrically connected to the second type semiconductor layer; and a first extended metal layer connected to the first pad and a second extended metal layer connected to the second pad.