Patents by Inventor Udo Hoss
Udo Hoss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120138484Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution and/or improved sensitivity and/or reduced sensitivity variation of the sensing layer by inclusion of a thickener and/or an enzyme stabilizer in the sensing layer. Embodiments of the present disclosure also relate to transition metal complexes having at least one pyridine boronic acid ligand are also described. Aspects of the disclosure include transition metal complexes chemically bonded to a polymer, such as a sensing layer polymer. The sensing layer is disposed on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.Type: ApplicationFiled: November 16, 2011Publication date: June 7, 2012Inventors: Balasubrahmanya S. Bommakanti, Udo Hoss, Gary Sandhu
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Publication number: 20120088995Abstract: Methods and devices for providing application specific integrated circuit architecture for a two electrode analyte sensor or a three electrode analyte sensor are provided. Systems and kits employing the same are also provided.Type: ApplicationFiled: October 6, 2011Publication date: April 12, 2012Applicant: Abbott Diabetes Care Inc.Inventors: Martin J. Fennell, Jean-Pierre Cole, Theodore John Kunich, Udo Hoss, Benjamin Jay Feldman, Zenghe Liu
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Publication number: 20120028283Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a membrane structure with an analyte permeability that is substantially temperature independent. The devices also include a sensing layer disposed on a working electrode of in vivo analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.Type: ApplicationFiled: July 27, 2011Publication date: February 2, 2012Inventors: Udo Hoss, Benjamin J. Feldman, Tianmei Ouyang
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Publication number: 20120004524Abstract: The methods and apparatus for detecting an analyte in blood are useful for detecting an analyte in tissue of a subject. The apparatus comprises a sensor, which comprises an elongated conductive material having a protrudent end, the protrudent end comprising an electrode that detects the presence of an analyte; a substrate affixed to the conductive material; and a support having an external surface, a proximal end, and a distal end. The conductive material is positioned on the support and the protrudent end of the conductive material protrudes beyond the distal end of the support. Optionally, the sensor is suspended within the lumen of a venous flow device. Typically, only a portion of the sensor is suspended within the lumen of the venous flow device, said portion comprising the protrudent end of the conductive material. Alternatively, the conductive material is positioned on the external surface of the intravenous infusion catheter.Type: ApplicationFiled: September 15, 2011Publication date: January 5, 2012Applicant: MEDTRONIC MINIMED, INC.Inventors: Nannette M. Van Antwerp, Udo Hoss
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Publication number: 20110282321Abstract: A system and method for controlling and monitoring a diabetes-management system through the use of a model that predicts or estimates future dynamic states of glucose and insulin from variables such as insulin delivery or exogenous glucose appearance as well as inherent physiological parameters. The model predictive estimator can be used as an insulin bolus advisor to give an apriori estimate of postprandial glucose for a given insulin delivery profile administered with a known meal to optimize insulin delivery; as a supervisor to monitor the operation of the diabetes-management system; and as a model predictive controller to optimize the automated delivery of insulin into a user's body to achieve a desired blood glucose profile or concentration. Open loop, closed-loop, and semi-closed loop embodiments of the invention utilize a mathematical metabolic model that includes a Minimal Model, a Pump Delivery to Plasma Insulin Model, and a Meal Appearance Rate Model.Type: ApplicationFiled: June 27, 2011Publication date: November 17, 2011Applicant: MEDTRONIC MINIMED, INC.Inventors: GARRY M. STEIL, Sami S. Kanderian, JR., Martin T. Cantwell, Udo Hoss
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Publication number: 20110282320Abstract: A system and method for controlling and monitoring a diabetes-management system through the use of a model that predicts or estimates future dynamic states of glucose and insulin from variables such as insulin delivery or exogenous glucose appearance as well as inherent physiological parameters. The model predictive estimator can be used as an insulin bolus advisor to give an apriori estimate of postprandial glucose for a given insulin delivery profile administered with a known meal to optimize insulin delivery; as a supervisor to monitor the operation of the diabetes-management system; and as a model predictive controller to optimize the automated delivery of insulin into a user's body to achieve a desired blood glucose profile or concentration. Open loop, closed-loop, and semi-closed loop embodiments of the invention utilize a mathematical metabolic model that includes a Minimal Model, a Pump Delivery to Plasma Insulin Model, and a Meal Appearance Rate Model.Type: ApplicationFiled: June 27, 2011Publication date: November 17, 2011Applicant: MEDTRONIC MINIMED, INC.Inventors: GARRY M. STEIL, Sami S. Kanderian, JR., Martin T. Cantwell, Udo Hoss
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Publication number: 20110257495Abstract: Method and system for determining real time analyte concentration including an analyte sensor having a portion in fluid contact with an interstitial fluid under a skin layer, an on-body electronics including a housing coupled to the analyte sensor and configured for positioning on the skin layer, the on-body electronics housing including a plurality of electrical contacts , on the housing; and a data analysis unit having a data analysis unit housing and a plurality of probes , on the housing. Each of the probes configured to electrically couple to a respective electrical contact when the data analysis unit is positioned in physical contact with the on-body electronics. The one or more signals on the probes correspond to one or more of a substantially real time monitored analyte concentration level (MACL), MACL over a predetermined time period, or a rate of change of the MACL, or combinations thereof, are provided.Type: ApplicationFiled: April 14, 2011Publication date: October 20, 2011Inventors: Udo Hoss, Benjamin J. Feldman, Zenghe Liu, Hyun Cho, Benjamin M. Rush
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Patent number: 8032198Abstract: The methods and apparatus for detecting an analyte in blood are useful for detecting an analyte in tissue of a subject. The apparatus comprises a sensor, which comprises an elongated conductive material having a protrudent end, the protrudent end comprising an electrode that detects the presence of an analyte; a substrate affixed to the conductive material; and a support having an external surface, a proximal end, and a distal end. The conductive material is positioned on the support and the protrudent end of the conductive material protrudes beyond the distal end of the support. Optionally, the sensor is suspended within the lumen of a venous flow device. Typically, only a portion of the sensor is suspended within the lumen of the venous flow device, said portion comprising the protrudent end of the conductive material. Alternatively, the conductive material is positioned on the external surface of the intravenous infusion catheter.Type: GrantFiled: February 7, 2006Date of Patent: October 4, 2011Assignee: Medtronic MiniMed, Inc.Inventors: Nannette M. Van Antwerp, Udo Hoss
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Publication number: 20110213225Abstract: Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user.Type: ApplicationFiled: August 31, 2010Publication date: September 1, 2011Applicant: Abbott Diabetes Care Inc.Inventors: Daniel Milfred Bernstein, Martin J. Fennell, Mark Kent Sloan, Michael Love, Lei He, Christopher Allen Thomas, Udo Hoss, Benjamin Jay Feldman, Kenneth J. Doniger, Gary Ashley Stafford, Gary Alan Hayter, Phillip Yee, Namvar Kiaie, Jean-Pierre Cole, Hung Dinh, Marc Barry Taub, Louis Pace, Jeffrey Mario Sicurello
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Patent number: 8000763Abstract: The present disclosure provides electrode structures and integrated electrode structures having one or more conductive materials coextruded with one or more dielectric materials. The disclosed electrode structures can be configured for use as analyte sensors. Also provided, are methods of making and using the electrode structures and integrated electrode structures described herein.Type: GrantFiled: June 30, 2009Date of Patent: August 16, 2011Assignee: Abbott Diabetes Care Inc.Inventors: John C. Mazza, Songbiao Zhang, Udo Hoss, Christopher Thomas
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Publication number: 20110160696Abstract: An injection port comprises a body having an outlet delivery cannula configured to pierce subcutaneous tissue of a patient to deliver medication. The port includes multiple injection sites, each of which can be used multiple times, and each of which is sealed. Each injection port is configured to temporarily receive a delivery device and reseal itself when the delivery device is removed. In one embodiment, a seal includes a pierceable stationary septum that reseals itself when a sharp cannula is removed. One injection site also includes locking features to receive a locking device of a delivery device and temporarily lock the delivery device in place at the injection site. The locking device may later be unlocked when delivery is complete and removed. In one application, a diabetic may use one injection site for syringes during the day and the locking injection site for a insulin pump during sleeping hours.Type: ApplicationFiled: December 30, 2010Publication date: June 30, 2011Applicant: ABBOTT DIABETES CARE INC.Inventor: Udo Hoss
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Publication number: 20110130988Abstract: A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.Type: ApplicationFiled: January 11, 2011Publication date: June 2, 2011Applicant: MEDTRONIC MINIMED, INC.Inventors: RAJIV SHAH, Bahar Reghabi, James L. Henke, Wayne A. Morgan, Gopikrishnan Soundararajan, David Y. Choy, Peter Schultz, Udo Hoss
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Publication number: 20110124994Abstract: Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved signal response and stability by inclusion of a coating including a hydrogel, a crosslinker, and a swelling modulator, where the coating is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.Type: ApplicationFiled: November 24, 2009Publication date: May 26, 2011Inventors: Balasubrahmanya S. Bommakanti, Gary Sandhu, Udo Hoss
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Publication number: 20110125446Abstract: A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic—cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.Type: ApplicationFiled: January 11, 2011Publication date: May 26, 2011Applicant: MEDTRONIC MINIMED, INC.Inventors: RAJIV SHAH, Bahar Reghabi, James L. Henke, Wayne A. Morgan, Gopikrishnan Soundararajan, David Y. Choy, Peter Schultz, Udo Hoss
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Publication number: 20110124993Abstract: Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of the sensing layer by inclusion of a self-polymerizing hydrogel, where the sensing layer is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.Type: ApplicationFiled: November 24, 2009Publication date: May 26, 2011Inventors: Balasubrahmanya S. Bommakanti, Gary Sandhu, Udo Hoss
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Publication number: 20110120865Abstract: Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of the sensing layer by inclusion of a high-boiling point solvent, where the sensing layer is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.Type: ApplicationFiled: November 24, 2009Publication date: May 26, 2011Inventors: Balasubrahmanya S. Bommakanti, Gary Sandhu, Udo Hoss, Geoffrey McGarraugh
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Publication number: 20110125447Abstract: A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.Type: ApplicationFiled: January 11, 2011Publication date: May 26, 2011Applicant: MEDTRONIC MINIMED, INC.Inventors: Rajiv Shah, Bahar Reghabi, James L. Henke, Wayne A. Morgan, Gopikrishnan Soundararajan, David Y. Choy, Peter Schultz, Udo Hoss
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Publication number: 20110106480Abstract: A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.Type: ApplicationFiled: January 11, 2011Publication date: May 5, 2011Applicant: MEDTRONIC MINIMED, INC.Inventors: RAJIV SHAH, Bahar Reghabi, James L. Henke, Wayne A. Morgan, Gopikrishnan Soundararajan, David Y. Choy, Peter Schultz, Udo Hoss
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Publication number: 20110101995Abstract: A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.Type: ApplicationFiled: January 11, 2011Publication date: May 5, 2011Applicant: MEDTRONIC MINIMED, INC.Inventors: RAJIV SHAH, Bahar Reghabi, James L. Henke, Wayne A. Morgan, Gopikrishnan Soundararajan, David Y. Choy, Peter Schultz, Udo Hoss
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Publication number: 20110106479Abstract: A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.Type: ApplicationFiled: January 11, 2011Publication date: May 5, 2011Applicant: MEDTRONIC MINIMED, INC.Inventors: RAJIV SHAH, Bahar Reghabi, James L. Henke, Wayne A. Morgan, Gopikrishnan Soundarapajan, David Y. Choy, Peter Schultz, Udo Hoss