Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.

Abstract: The disclosure relates to a metal-air battery with dispersed carbon in the electrolyte solution.

Abstract: The present invention relates to the use of a powder which comprises specific polyesters for shaping processes, and to moldings produced powder. The shaping processes are layer-by-layer processes which use powder, which comprises selectively melting regions of a powder layer by applying electromagnetic energy. Selectivity can although there is no intention to restrict the invention thereto be achieved via a mask, or application of an inhibitor, of an absorber or of a susceptor, or via focusing of the energy input. After cooling, the regions then solidified can be removed as moldings from the powder bed. The process occurs by using a polyester powder obtained from an alcohol and from a diacid with no use of any aromatic monomer unit. These polyester powders combine high crystallinity and low melting point, and makes the construction process more reliable while good component quality, mechanical properties, density, dimensional accuracy, and low shrinkage are realized.

Abstract: A task often encountered in very recent times is the rapid provision of prototypes. Particularly suitable processes are those based on pulverulent materials and in which the desired structures are produced layer-by-layer through selective melting and solidification. The invention provides the constitution, production and use of a copolyamide powder which was produced using the following monomer units: a) laurolactam or ?-aminoundecanoic acid, and also b) dodecanedioic acid, and either c) decanediamine or dodecanediamine, in shaping processes, and also to moldings produced through a layer-by-layer process which selectively melts regions of a powder layer, using this specific powder. Once the regions previously melted layer-by-layer have been cooled and solidified, the molding can be removed from the powder bed. The moldless layer-by-layer processes for the production of components using the copolyamide powder result in simplified and more reliable conduct of the process and better recyclability.

Abstract: A powder which is capable of being used in a layer-by-layer process in which regions of the respective pulverulent layer are selectively melted and, after cooling, are fixed, contains a mixture of diacid-regulated polyamide and diamine-regulated polyamide and/or diacid-regulated copolyamide and diamine-regulated copolyamide.

Abstract: The present invention relates to gold nanocluster compounds, especially gold nanoparticles, having a reduced toxicity, especially cytotoxicity, which are preferably appropriate for use in medical diagnostics such as medical imaging (e.g. X-ray, CT etc.), said gold nanocluster compounds comprising a core of at least one gold atom and at least one ligand bound to said core, wherein the reduction of toxicity, especially cytotoxicity, of said gold nanocluster compound is controlled and/or adjusted via its ligand structure and/or its ligand chemistry.

Abstract: The present invention relates to a composite powder which comprises polymer powder and porous glass beads, and to the use of this composite powder for shaping processes, and also to mouldings produced from this composite powder.

Abstract: A device and a method are provided for the analysis of a sample plate on which at least two material samples are situated. In the method, one impedance spectrum is measured for each of the material samples. As a function of the respectively measured impedance spectrum, a configuration of a circuit equivalent is determined which includes at least one electronic component. Then, for an error minimization computation, starting values for the components of the respective circuit equivalents are determined. In the error minimization computation, a theoretical impedance spectrum is calculated for at least one of the material samples, based on the impedance spectrum measured for the material sample, as well as the starting values for the components of the respective circuit equivalent, and fit values are determined for the components of the respective circuit equivalent.

Abstract: The present invention relates to a composite powder of polymer powder and porous glass beads, and to the use of this composite powder for shaping processes, and also to mouldings produced from this composite powder.

Abstract: The use of one or more wavefront modulators in the observation beam path and/or illumination beam path of a microscope provide various advantageous results. Such modulators may be adapted to change the phase and/or the amplitude of light in such a way to carry out displacement and shaping of the focus in the object space and correction of possible aberrations. The possible areas of use include confocal microscopy, laser-assisted microscopy, conventional light microscopy and analytic microscopy.

Abstract: A micro electronic component, preferably in the form of an electronic memory, includes the use of clusters as an electronic memory. Also disclosed as part of the present invention is a method for fabricating a micro electronic component. The present invention contemplates fabrication of an especially compact electronic memory that works especially with single-electron transistors or single-electronic transfers. According to the present invention, clusters with a metallic cluster nucleus are arranged in parallel grooves essentially in lines or rows and are connected individually to first and second connecting electrodes, such that individually the clusters can be electrically modified or polled independently of each other.

Abstract: A task often encountered in very recent times is the rapid provision of prototypes. Particularly suitable processes are those based on pulverulent materials and in which the desired structures are produced layer-by-layer through selective melting and solidification. The invention provides the constitution, production and use of a copolyamide powder which was produced using the following monomer units: a) laurolactam or ?-aminoundecanoic acid, and also b) dodecanedioic acid, and either c) decanediamine or dodecanediamine, in shaping processes, and also to mouldings produced through a layer-by-layer process which selectively melts regions of a powder layer, using this specific powder. Once the regions previously melted layer-by-layer have been cooled and solidified, the moulding can be removed from the powder bed. The mouldless layer-by-layer processes for the production of components using the copolyamide powder result in simplified and more reliable conduct of the process and better recyclability.

Abstract: Moldings can be produced from a polymer powder containing at least one block polyetheramide containing an oligoamide dicarboxylic acid and a polyetheramine; wherein the powder is suitable for use in a layer-by-layer process in which regions of a powder layer are selectively melted via introduction of electromagnetic energy.

Abstract: The present invention relates to a composite powder of polymer powder and porous glass beads, and to the use of this composite powder for shaping processes, and also to mouldings produced from this composite powder.

Abstract: The present invention relates to the use of at least one gold nanocluster compound in the manufacture of a pharmaceutical composition or medicament for the prophylactic and/or therapeutic (curative) treatment of a disease, especially a tumor and/or cancer disease. The gold nanocluster compound having a defined particle size, especially a defined size of the core of said gold nanocluster compound, the size ranging from 0.5 nm to 10 nm, the outer limits of this range being included. Especially, the gold nanocluster compounds used possess size-dependent cytotoxic properties, stimulating or inducing cellular death when treating and/or contacting respective cells, especially tumor and/or cancer cells, with the gold nanocluster compounds either via apoptosis or via necrosis, depending on the respective gold cluster size or core size.

Abstract: An optoelectronic component with a photonic crystal, which also has an electronic band gap, and a method for controlling tunneling electron currents by means of photons are proposed. Essentially loss-free and very fast switching is enabled in that a photonic crystal has a defect mode in its photonic band gap for photons with such an energy that electron transitions, especially in the form of single-electron tunneling processes between adjacent ligand-stabilized metal clusters, can be induced by the irradiation of corresponding photons due to at least one defect site.

Abstract: Interlining with a double dot for the coating and/or lamination of sheetlike structures, wherein upper dot is based on an amine-terminated, crosslinkable copolyamide and the lower dot is of an OH-terminated copolyester and further comprises a crosslinker and an acrylic and/or PU dispersion.

Abstract: A device and a method are provided for the analysis of a sample plate on which at least two material samples are situated. In the method, one impedance spectrum is measured for each of the material samples. As a function of the respectively measured impedance spectrum, a configuration of a circuit equivalent is determined which includes at least one electronic component. Then, for an error minimization computation, starting values for the components of the respective circuit equivalents are determined. In the error minimization computation, a theoretical impedance spectrum is calculated for at least one of the material samples, based on the impedance spectrum measured for the material sample, as well as the starting values for the components of the respective circuit equivalent, and fit values are determined for the components of the respective circuit equivalent.

Abstract: The present invention relates to the use of a powder which comprises specific polyesters for shaping processes, and to moldings produced powder. The shaping processes are layer-by-layer processes which use powder, which comprises selectively melting regions of a powder layer by applying electromagnetic energy. Selectivity can although there is no intention to restrict the invention thereto be achieved via a mask, or application of an inhibitor, of an absorber or of a susceptor, or via focusing of the energy input. After cooling, the regions then solidified can be removed as moldings from the powder bed. The process occurs by using a polyester powder obtained from an alcohol and from a diacid with no use of any aromatic monomer unit. These polyester powders combine high crystallinity and low melting point, and makes the construction process more reliable while good component quality, mechanical properties, density, dimensional accuracy, and low shrinkage are realized.

Abstract: A process for confocal microscopy is disclosed in which laser light is coupled into a microscope beam path, directed successively with respect to time onto different locations of a specimen, and an image of the scanned plane is generated from the light reflected and emitted by the irradiated locations. A change in the spectral composition and in the intensity of light is are carried out during the deflection of the laser beam from location to location, while the deflection continues in an uninterrupted manner. In this way , so that at least two adjacent locations of the specimen located next to one another are acted upon by light with different spectral characteristics and by laser radiation of different intensity. By periodically interrupting the coupling in of the laser light during the deflection of the microscope beam path, it is made possible that only selected portions of the image field are acted upon by the laser radiation. A laser scanning microscope for carrying out this process is also disclosed.