Patents by Inventor Ute Schellenberger
Ute Schellenberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11959090Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: April 28, 2021Date of Patent: April 16, 2024Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Daniel J Altier, Jennifer Kara Barry, Ryan Michael Gerber, Steven D Gruver, Lu Liu, Ute Schellenberger, Jun-Zhi Wei, Weiping Xie, Nasser Yalpani, Genhai Zhu
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Publication number: 20240117050Abstract: Novel human CD3 antigen-binding polypeptides and their preparation and use in the treatment and/or diagnosis of various diseases are provided, as well as bispecific antibody molecules capable of activating immune effector cells and their use in diagnosis and/or treatment of various diseases.Type: ApplicationFiled: October 12, 2023Publication date: April 11, 2024Inventors: Ute Schellenberger, Nathan Trinklein, Wim van Schooten
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Publication number: 20240018194Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: August 30, 2023Publication date: January 18, 2024Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: STEVEN D. GRUVER, HEATHER KOZY, JESSICA O'REAR, BARBARA ROSEN, UTE SCHELLENBERGER, JUN-ZHI WEI, WEIPING XIE, XIAOHONG ZHONG, GENHAI ZHU
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Publication number: 20230348930Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: June 29, 2023Publication date: November 2, 2023Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: JENNIFER KARA BARRY, ANGEL ELIZABETH GRACE D′OLIVIERA, RYAN MICHAEL GERBER, KEVIN HAYES, ALBERT L LU, AMY LUM, UTE SCHELLENBERGER, ERIC SCHEPERS, JEFFREY SOPA, WEIPING XIE, NASSER YALPANI
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Patent number: 11780891Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: November 3, 2021Date of Patent: October 10, 2023Inventors: Steven D Gruver, Heather Kozy, Jessica O'Rear, Barbara Rosen, Ute Schellenberger, Jun-Zhi Wei, Weiping Xie, Xiaohong Zhong, Genhai Zhu
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Patent number: 11739344Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: June 14, 2018Date of Patent: August 29, 2023Inventors: Jennifer Kara Barry, Angel Elizabeth Grace D'Oliviera, Ryan Michael Gerber, Kevin Hayes, Albert L Lu, Amy Lum, Ute Schellenberger, Eric Schepers, Jeffrey Sopa, Weiping Xie, Nasser Yalpani
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Publication number: 20230257473Abstract: Multi-specific, human heavy chain antibodies (e.g., UniAbs™) binding to BCMA are disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by the expression of BCMA.Type: ApplicationFiled: June 30, 2021Publication date: August 17, 2023Inventors: Nathan Trinklein, Katherine Harris, Harbani Malik, Ute Schellenberger, Omid Vafa, Shelley Force Aldred
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Publication number: 20230203161Abstract: Multispecific, human heavy chain antibodies (e.g., UniAbs™) that have modified heavy chain constant regions that impart advantageous properties are provided. The invention further concerns methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by expression of one or more of the binding targets described herein.Type: ApplicationFiled: April 29, 2021Publication date: June 29, 2023Inventors: Katherine Harris, Ute Schellenberger, Omid Vafa, Nathan Trinklein, Wim Van Schoofen, Shelley Force Aldred, Duy Pham, Starlynn Clarke
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Publication number: 20230183734Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: October 9, 2019Publication date: June 15, 2023Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: DAVID CHARLES CERF, STEVEN D GRUVER, LU LIU, YOUNG-JUN PARK, UTE SCHELLENBERGER, JUN-ZHI WEI, WEIPING XIE, GENHAI ZHU
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Publication number: 20220389445Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: June 7, 2022Publication date: December 8, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: DAVID CHARLES CERF, JAMES J ENGLISH, CAROL A HENDRICK, LU LIU, JARRED KENNETH ORAL, PHILLIP A PATTEN, BARBARA ROSEN, UTE SCHELLENBERGER, INGRID UDRANSZKY, JUN-ZHI WEI, GENHAI ZHU
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Publication number: 20220340620Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: April 6, 2022Publication date: October 27, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: SCOTT DIEHN, JAMES J. ENGLISH, LU LIU, AZALEA S. ONG, JARRED KENNETH ORAL, BARBARA ROSEN, UTE SCHELLENBERGER, INGRID UDRANSZKY, JUN-ZHI WEI, WEIPING XIE, GENHAI ZHU
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Publication number: 20220332820Abstract: Multispecific, human heavy chain antibodies (e.g., UniAbs™) that have modified heavy chain constant regions that impart advantageous properties are provided. The invention further concerns methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by expression of one or more of the binding targets described herein.Type: ApplicationFiled: November 23, 2021Publication date: October 20, 2022Inventors: Katherine Harris, Ute Schellenberger, Omid Vafa, Nathan Trinklein, Wim van Schooten, Shelley Force Aldred, Duy Pham, Starlynn Clarke
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Publication number: 20220251597Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: January 27, 2022Publication date: August 11, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: HEATHER KOZY, JARRED KENNETH ORAL, UTE SCHELLENBERGER, JUN-ZHI WEI, WEIPING XIE, XIAOHONG ZHONG, GENHAI ZHU
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Patent number: 11396660Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: February 10, 2020Date of Patent: July 26, 2022Inventors: Heather Kozy, Jarred Kenneth Oral, Ute Schellenberger, Jun-Zhi Wei, Weiping Xie, Xiaohong Zhong, Genhai Zhu
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Patent number: 11390681Abstract: Multispecific, human heavy chain antibodies (e.g., UniAbs™) that have modified heavy chain constant regions that impart advantageous properties are provided. The invention further concerns methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by expression of one or more of the binding targets described herein.Type: GrantFiled: June 14, 2021Date of Patent: July 19, 2022Assignee: TeneoTwo, Inc.Inventors: Katherine Harris, Ute Schellenberger, Omid Vafa, Nathan Trinklein, Wim van Schooten, Shelley Force Aldred, Duy Pham, Udaya Rangaswamy
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Patent number: 11325949Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: April 6, 2020Date of Patent: May 10, 2022Inventors: Scott Diehn, James J English, Lu Liu, Azalea S Ong, Jarred Kenneth Oral, Barbara Rosen, Ute Schellenberger, Ingrid Udranszky, Jun-Zhi Wei, Weiping Xie, Genhai Zhu
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Publication number: 20220089729Abstract: Multispecific, human heavy chain antibodies (e.g., UniAbs™) that have modified heavy chain constant regions that impart advantageous properties are provided. The invention further concerns methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by expression of one or more of the binding targets described herein.Type: ApplicationFiled: June 14, 2021Publication date: March 24, 2022Inventors: Katherine Harris, Ute Schellenberger, Omid Vafa, Nathan Trinklein, Wim van Schooten, Shelley Force Aldred, Duy Pham, Udaya Rangaswamy
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Publication number: 20220056469Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: September 10, 2019Publication date: February 24, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: DANIEL J ALTIER, JENNIFER KARA BARRY, CHRISTIAN BARTHOLOMAY, HUA DONG, RYAN MICHAEL GERBER, JACOB GILLIAM, STEVEN D GRUVER, LU LIU, JARRED KENNETH ORAL, JESSICA O'REAR, UTE SCHELLENBERGER, ERIC SCHEPERS, DANIEL JAMES THORPE, THOMAS CHAD WOLFE, WEIPING XIE, NASSER YALPANI, YOU YOU, GENHAI ZHU
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Publication number: 20220056082Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: November 3, 2021Publication date: February 24, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: STEVEN D GRUVER, HEATHER KOZY, JESSICA O'REAR, BARBARA ROSEN, UTE SCHELLENBERGER, JUN-ZHI WEI, WEIPING XIE, XIAOHONG ZHONG, GENHAI ZHU
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Publication number: 20220024993Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: October 12, 2021Publication date: January 27, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: STEVEN D GRUVER, LU LIU, BARBARA ROSEN, UTE SCHELLENBERGER, JUN-ZHI WEI, WEIPING XIE, GENHAI ZHU