Abstract: In one embodiment, a method includes determining, by a router, a common prefix pool from a transport interface associated with a transport virtual private network (VPN). The method also includes identifying, by the router, a prefix associated with a service VPN and generating, by the router, an IPv6-to-IPv6 Network Address Translation (NAT66) prefix translation using the common prefix pool and the prefix. The NAT66 prefix translation includes a predetermined prefix length. The method further includes automatically installing, by the router, the NAT66 prefix translation into a translation table.

Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2”). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

Abstract: Embodiments of the present disclosure provide a control method and a control device for an electric switch, and an electric switch. The control method includes: obtaining a voltage signal representing a control voltage, the control voltage input to the electric switch and applied to an electromagnetic assembly of the electric switch via a regulation device of the electric switch; determining, based on the voltage signal obtained, a target control parameter for the electromagnetic assembly, the target control parameter comprising at least one of a target voltage and a target current; and generating, based on the target control parameter determined, a control signal for the regulation device, to cause the electromagnetic assembly to drive a movable contact of the electric switch to contact a static contact of the electric switch. The solution of the present disclosure can effectively reduce wear of contact points of contacts, to thus prolong the service life of the electric switch.

Abstract: A water-soluble unit dose article containing a water-soluble film a liquid laundry detergent composition having a first anionic surfactant, and a method of making the water-soluble unit dose article.

Abstract: Method of generating frustration score starts with processor receiving data associated with interactions by users with website including webpages displayed during sessions. Processor generates page view scores based on page view experience indicators and zone experience indicators associated with the webpages, generates session scores based on the page view scores and session experience indicators, and generates webpage scores based on page view scores. Processor identifies the webpage associated with highest level of frustration based on page view and webpage scores and identifies the session that is associated with highest level of frustration based on the session scores. Processor causes a user interface to be displayed on a display device that includes a visualization of interactions by a user with the website associated with the session with the highest level of frustration and an identification of the webpage associated with the highest level of frustration. Other embodiments are described herein.

Abstract: A conversation augmentation system can automatically augment a conversation with content items based on natural language from the conversation. The conversation augmentation system can select content items to add to the conversation based on determined user “intents” generated using machine learning models. The conversation augmentation system can generate intents for natural language from various sources, such as video chats, audio conversations, textual conversations, virtual reality environments, etc. The conversation augmentation system can identify constraints for mapping the intents to content items or context signals for selecting appropriate content items. In various implementations, the conversation augmentation system can add selected content items to a storyline the conversation describes or can augment a platform in which an unstructured conversation is occurring.

Abstract: Wearable electronic devices, such as smart watches, can be provided with a band for securing the device to a wearer. The device and the band can include near-field communications (NFC) components that allow the device to uniquely identify the band. Device operations such as the color, theme, or content displayed on the device can be based, in part, on the identification of a particular band. The band may include a miniature NFC tag in an attachment portion of the band that is configured to be received in a recess in a housing of the device. An NFC module for reading the NFC tag can be provided within the recess of the housing, so that the attachment portion of the band and the recess in the device housing position and align the NFC tag with the NFC module when the band is attached to the device.

Abstract: A collapsible and self-erecting polyhedron system is provided. The system includes a collapsible and self-erecting box. The box comprises cardboard and includes outer surfaces upon which images (e.g., photographic reproductions), graphics, and text are printed to provide a three-dimensional greeting card. The three-dimensional greeting card (the box) is collapsed and placed into an envelope, and upon being removed from the envelope, automatically self-erects providing a fun and exciting experience. Confetti also is included within the box that is ejected during the box self-erecting, thereby providing even more enjoyment.

Abstract: A method of generating customizable goal representation is disclosed. A request from a user to view a goal representation is received. A flexible goal ontology is accessed that comprises one or more goal entities, one or more goal relationships between the goal entities, or one or more goal properties, the one or more goal properties including one or more metadata attributes relating to the one or more goal entities. A set of mapping rules is obtained that defines mappings between one or more goals. The set of mapping rules is evaluated to assemble a customized goal representation tailored to the user. The customized goal representation is updated based on a revaluation of the mapping rules affected by changes to the one or more goal entities, the one or more goal relationships, or the one or more properties.

Abstract: Method of generating frustration score starts with processor receiving data associated with interactions by users with website including webpages displayed during sessions. Processor generates page view scores based on page view experience indicators and zone experience indicators associated with the webpages, generates session scores based on the page view scores and session experience indicators, and generates webpage scores based on page view scores. Processor identifies the webpage associated with highest level of frustration based on page view and webpage scores and identifies the session that is associated with highest level of frustration based on the session scores. Processor causes a user interface to be displayed on a display device that includes a visualization of interactions by a user with the website associated with the session with the highest level of frustration and an identification of the webpage associated with the highest level of frustration. Other embodiments are described herein.

Abstract: The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2”). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

Abstract: A method of scheduling input/output operations for a storage system including determining a deadline for a storage operation, wherein the deadline is dependent on an expected latency of the storage operation; adding the storage operation to a queue of storage operations; and reordering the queue dependent upon the deadline of the storage operation and one or more deadlines of one or more storage operations in the queue of storage operations.

Abstract: A collapsible and self-erecting polyhedron system is provided. The system includes a collapsible and self-erecting box. The box comprises cardboard and includes outer surfaces upon which images (e.g., photographic reproductions), graphics, and text are printed to provide a three-dimensional greeting card. The three-dimensional greeting card (the box) is collapsed and placed into an envelope, and upon being removed from the envelope, automatically self-erects providing a fun and exciting experience. Confetti also is included within the box that is ejected during the box self-erecting, thereby providing even more enjoyment.

Abstract: A method for monitoring a treatment of a subject having a musculoskeletal disorder is provided. The method includes measuring a first expression level of at least two biomarkers at a treatment site prior to the treatment and measuring a second expression level of the at least two biomarkers at the treatment site after the treatment begins. The method further includes comparing the first expression level of the at least two biomarkers prior to the treatment to the second expression level of the at least two biomarkers post treatment and continuing the treatment, altering the treatment or stopping the treatment based on the comparison. A method of treating a musculoskeletal disorder in a subject is also provided. The method includes removing a aggrecan-hyaluronan matrix from a treatment site in the subject.

Abstract: Drip chambers are described herein. A drip chamber comprises an inlet, an outlet, and a chamber body. The chamber body defines a chamber volume in fluid communication with the inlet and the outlet. The chamber body is movable between a collapsed configuration having a first volume and an expanded configuration having a second volume. The second volume is larger than the first volume, and the chamber body is configured to be moved from the collapsed configuration to the expanded configuration to draw in a medical fluid from the inlet into the chamber volume to prime the drip chamber.

Abstract: Drip chambers are described herein. A drip chamber comprises an inlet, an outlet, and a chamber body. The chamber body defines a chamber volume in fluid communication with the inlet and the outlet. The chamber body is movable between a collapsed configuration having a first volume and an expanded configuration having a second volume. The second volume is larger than the first volume, and the chamber body is configured to be moved from the collapsed configuration to the expanded configuration to draw in a medical fluid from the inlet into the chamber volume to prime the drip chamber.

Abstract: A method for efficient reads by reconstruction may determining an expected read latency for reading data from a primary read location of a plurality of storage devices, determining an expected reconstruction latency for reconstructing the data using reconstruction data, wherein portions of the reconstruction data are stored at a plurality of alternative read locations of the plurality of storage devices, reading the portions of the reconstruction data from the plurality of alternative read locations of the plurality of storage devices, and reconstructing the data stored at the primary read location using the reconstruction data, wherein the expected reconstruction latency is lower than the expected read latency.

Abstract: A method of scheduling input/output operations for a storage system including determining a deadline for a storage operation, wherein the deadline is dependent on an expected latency of the storage operation; adding the storage operation to a queue of storage operations; and reordering the queue dependent upon the deadline of the storage operation and one or more deadlines of one or more storage operations in the queue of storage operations.