Abstract: Disclosed is a method for the treatment of AD, wherein an immune stimulating pharmaceutical composition comprising an aluminium salt is administered to a patient having AD or having a risk to develop AD in an effective amount.

Abstract: The invention discloses Interferon alpha (IFN-?) messenger-RNA (mRNA), wherein the mRNA has a 5? CAP region, a 5? untranslated region (5?-UTR), a coding region, a 3? untranslated region (3?-UTR) and a poly-adenosine tail (poly-A tail), for use in the prevention and treatment of non-melanoma skin cancer (NMSC) and kits for administrating this IFN-? mRNA to a human patient.

Abstract: The invention discloses aluminium oxyhydroxide for use in the treatment and prevention of AD.

Abstract: A crash assembly having a crash strut for a wheel of a motor vehicle, which is connected to a tie rod assembly that has at least one tie rod strut. The tie rod strut is connected to a first end of the crash strut via at least one tie rod-side connection module. A second end of the crash strut is connected to a body of the motor vehicle via a body-side connection module.

Abstract: A vehicle (52) is provided having at least one battery (35) for supplying at least one drive of the vehicle (52) with electricity, and having at least one gas storage device (33). At least one part of the gas storage device (33) and at least one part of the battery (35) are combined in a structural unit (32) and arranged on an underbody (31) of the vehicle (52). A method for charging a battery (35) in a vehicle (52) is also provided, in which method at least one part of a battery (35) combined in a structural unit (32) with at least one part of a gas storage device (33) is supplied with electricity by a fuel cell comprised by the vehicle (52).

Abstract: Method for operating a dirt collecting device for a sweeping vehicle or for a vacuum cleaner nozzle of a floor or upright vacuum cleaner, which each comprise a suction fan with controllable speed and/or power, wherein in a first method step, the suction power of the suction fan is set at such a low level that the suction pressure in the dirt collecting device or the vacuum cleaner nozzle is merely sufficient to convey and deposit the absorbed coarse dirt into the intermediate container, and to convey the absorbed fine dirt into a downstream collection container, (normal operation); and that in a second method step, the filling level in the intermediate container is detected with respect to the coarse dirt deposited therein; and that in a third method step, if the filling level in the intermediate container is exceeded, the suction power of the suction fan is increased such that the coarse dirt, which is temporarily deposited in the intermediate container, becomes dispersible and is conveyed into the downstrea

Abstract: An elevator system includes one or more elevator cars configured to travel along a hoistway. One or more rails extend along the hoistway and are operably connected to the one or more elevator cars to guide the one or more elevator cars along the hoistway. Each rail of the one or more rails includes a plurality of rail segments arranged end to end. Each rail segment is affixed to a hoistway wall to transfer vertical loads from the rail segment to the hoistway wall. Each rail segment is secured to the hoistway wall via a plurality of rail support brackets. The vertical loads are transferred from the rail segment to the hoistway wall via at least one rail support bracket of the plurality of rail support brackets.

Abstract: A method for the automatic irrigation of plants, wherein the temporal progression of soil moisture is determined from measured soil moisture values, and the progression is used for the calculation of an optimized irrigation time duration, such that both water excess in the soil and soil drying are avoided as much as possible. Preferably, the time duration of irrigation is constantly evaluated and optimized using comparisons of measured values with prespecified moisture and dryness threshold values, and automatically adjusted to changing environmental conditions and/or plant requirements.

Abstract: The invention relates to a method for the automatic irrigation of plants, wherein the temporal progression of soil moisture is determined from measured soil moisture values, and said progression is used for the calculation of an optimized irrigation time duration, such that both water excess in the soil and soil drying are avoided as much as possible. Preferably, the time duration of irrigation is constantly evaluated and optimized using comparisons of measured values with prespecified moisture- and dryness threshold values (GWmoist, GWdry), and automatically adjusted to changing environmental conditions and/or plant requirements.

Abstract: A tibial implant system has an ultra-high molecular weight polyethylene tibial insert which can engage with either one of two tibial trays through differing means of engagement. The tibial insert includes a locking wire and locking tab disposed along an anterior surface and a locking recess disposed along a posterior surface. A first polymeric tibial tray includes a bead along an anterior wall and an undercut area along a posterior wall. A second metallic tibial tray includes a plurality of barbs along an anterior wall and an undercut area along a posterior wall.

Abstract: The present invention relates to a vehicle (52) having at least one battery (35) for supplying at least one drive of the vehicle (52) with electricity, and at least one gas storage means (33), wherein at least one part of the gas storage means (33) and at least one part of the battery (35) are combined in a structural unit (32) and arranged on an underbody (31) of the vehicle (52). The present invention furthermore relates to a method for charging a battery (35) in a vehicle (52), in which method at least one part of a battery (35) combined in a structural unit (32) with at least one part of a gas storage means (33) is supplied with electricity by a fuel cell comprised by the vehicle (52).

Abstract: Disclosed is a method for diagnosing Alzheimer's disease (AD) wherein A?-specific antibodies in a biological sample of a person that is suspected of having AD are detected comprising the following steps: —contacting the sample with A?-aggregates or with particles having A?-aggregate like surfaces and allowing the A?-specific antibodies to bind to the A?-aggregates, and —detecting the A?-specific antibodies bound to the A?-aggregates by a single particle detection technique, preferably by fluorescence activated cell sorting (FACS); and wherein the amount of A?-specific antibodies detected is compared with the amount in a sample of known AD status.

Abstract: Disclosed is a method for the treatment of AD, wherein an immune stimulating pharmaceutical composition comprising an aluminium salt is administered to a patient having AD or having a risk to develop AD in an effective amount.

Abstract: The invention discloses aluminium oxyhydroxide for use in the treatment and prevention of AD.

Abstract: The invention discloses an aluminium salt for use in the treatment and prevention of dementias associated with ?-amyloid deposition, preferably AD.

Abstract: A motor vehicle has a processor device to run application programs in a first communication zone and a storage device for vehicle control data, by which a driving behavior of the motor vehicle is determined. The storage device is arranged in a second communication zone of the motor vehicle. In order to allow a modification of the vehicle control data at a later stage using an application program and thus provide protection against an undesired manipulation of the vehicle control data, the first and the second communication zones are coupled by a monitoring device that forwards new data, which an application program is attempting to transmit from the first communication zone into the second communication zone, to the second communication zone only if the monitoring device has detected that the new data leads to a safe motor vehicle driving behavior defined by a specified safety criterion.

Abstract: Described is an immunostimulatory oligodeoxynucleic acid molecule (ODN) having the structure according to formula (I), wherein any NMP is a 2? deoxynucleoside monophosphate or monothiophosphate, selected from the group consisting of deoxyadenosine-, deoxyguanosine-, deoxyinosine-, deoxycytosine-, deoxyuridine-, deoxythymidine-, 2-methyl-deoxyinosine-, 5-methyl-deoxycytosine-, deoxypseudouridine-, deoxyribosepurine-, 2-amino-deoxyribosepurine-, -6-S-deoxyguanine-, 2-dimethyl-deoxyguanosine- or N-isopentenyl-deoxyadenosine-monophosphate or -monothiophosphate, NUC is a 2? deoxynucleoside, selected from the group consisting of deoxyadenosine-, deoxyguanosine-, deoxyinosine-, deoxycytosine-, deoxyuridine-, deoxythymidine-, 2-methyl-deoxyinosine-, 5-methyl-deoxycytosine-, deoxypseudouridine-, deoxyribosepurine-, 2-amino-deoxyribosepurine-, 6-S-deoxyguanine-, 2-dimethyl-deoxyguanosine- or N-isopentenyl-deoxyadenosine, any X is O or S, a and b are integers from 0 to 100 with the proviso that a+b is between 4 and 150,

Abstract: The present invention relates to a composition comprising at least one mimotope of an epitope of alpha-synuclein for use in a method for preventing and/or treating ?-amyloidoses including Alzheimer's disease, wherein said at least one mimotope is coupled or fused to a pharmaceutically acceptable carrier protein selected from the group consisting of a non-toxic diphtheria toxin mutant, keyhole limpet hemocyanin (KLH), diphtheria toxin (DT), tetanus toxid (TT) and Haemophilus influenzae protein D (protein D).

Abstract: A motor vehicle has a processor device to run application programs in a first communication zone and a storage device for vehicle control data, by which a driving behavior of the motor vehicle is determined. The storage device is arranged in a second communication zone of the motor vehicle. In order to allow a modification of the vehicle control data at a later stage using an application program and thus provide protection against an undesired manipulation of the vehicle control data, the first and the second communication zones are coupled by a monitoring device that forwards new data, which an application program is attempting to transmit from the first communication zone into the second communication zone, to the second communication zone only if the monitoring device has detected that the new data leads to a safe motor vehicle driving behavior defined by a specified safety criterion.

Abstract: A method for preventing and/or treating a synucleinopathy, comprising administering a composition containing at least one mimotope of an epitope of alpha-synuclein, wherein said at least one mimotope is coupled or fused to a pharmaceutically acceptable carrier protein selected from the group consisting of a non-toxic diphtheria toxin mutant, keyhole limpet hemocyanin (KLH), diphtheria toxin (DT), tetanus toxid (TT) and Haemophilus influenzae protein D (protein D).