Abstract: Pharmaceutical composition containing at least one peptide or protein (fragment) with an immunomodulatory activity together with an adjuvant. The peptide is derived from a pathogenic agent or a tumour antigen. The adjuvant is capable of increasing the binding of the peptide to the cells of the individual to be treated or of increasing the entry of the peptide into the cells and strengthening the immunomodulatory activity of the peptide. Preferred adjuvants are basic polyamino acids such as polyarginine or polylysine, optionally conjugated with a cellular ligand such as a carbohydrate group or transferrin. The composition is particularly intended for use as a vaccine, e.g. as a tumour vaccine.

Abstract: The technology is based on the anisotropic plasma etching of organic polymer sheets partially protected by a metallic mask. The originality of the process is to pattern the surface properties by the same physical means as the one used for the three dimensional fabrication and simultaneously to this fabrication. Surface properties means, but are not limited to hydrophobicity, hydrophilicity, conductivity, reflectability, rugosity and more precisely the chemical and/or physical state of the surface. It is also possible to generate the desired fonctionalities, for instance carboxylic acid, ester, ether, amid or imid, during the etching process. The patterning of the different properties may be achieved by two different techniques that may be used separately or simultaneously.

Abstract: Polymer composites containing keratin and at least one polymer (e.g., polyurethane, polyethylene, polypropylene, polyamide, polyesters, polyvinyl chloride, polylactic acid, polyvinyl alcohol, polycaprolactone, polyhydroxy esther ether, polyhydroxybutyrate, polyhydroxyalkanoates, polystyrene, polycarbonate, polymethyl methacrylate, polybutadiene, polyisoprene, polyurethane, epoxies, or mixtures thereof; wherein polypropylene is not atactic polypropylene). Methods for producing the polymer composites are also provided. The properties of polymers are improved by the dispersion of cleaned, processed keratin material, preferably derived from poultry feathers, in the polymeric material. The keratin material can be in the form of fibers, particles, or large pieces from animal hair, nail, hoof, horn, or avian (e.g., poultry) feathers.

Abstract: The surge arrester contains a tubular encapsulation (1) of electrically conductive material that is filled with an insulating gas, an insulator (17) that is held on the encapsulation (1) and serves for supporting a current conductor (R) that is connected to a high voltage, an active part (2R) that is arranged in the encapsulation (1) and comprises at least one varistor column (3) that is aligned along the encapsulation axis (A) and a field control element (6). In order to maintain the manufacturing costs of this arrester at a low level, the field control element (6) and a first plug-type contact (16) of a plug connection (15) are held on the current conductor (R) of the insulator (17), and a high-voltage electrode (4) of the varistor column (3) that is connected in an electrically conductive fashion to the current conductor (R) via the plug connection (15) contains the second plug-type contact (14) of the plug connection (15).

Abstract: The invention relates to the use of inununostimulatory deoxyinosine/deoxyuridine containing oligodeoxynucleotides for pharmaceutical application, such as treating and preventing chronic infectious diseases, acute decrements in air flow, parasitic infections and the like.

Abstract: A method for manufacturing electrical connecting elements or semifinished products. Microvias are formed in a dielectric substrate layer by piercing a substrate layer (1) through a first conducting layer (3), which essentially covers an entire side of the substrate. The perforation depth (d) is at least equal to the total thickness of the substrate and the first conducting layer. The conductor material of the first conducting layer (3), during the piercing step, is deformed so that it partially covers the wall of the hole fabricated by the piercing process. Plating the first conducting layer with additional conductor material bridges the little remaining distance between the conductor material and the opposite side of the substrate layer.

Abstract: Polymer composites containing keratin and at least one polymer. Methods for producing the polymer composites are also provided. The properties of polymers are improved by the dispersion of cleaned, processed keratin material, preferably derived from poultry feathers, in the polymeric material. The keratin material can be in the form of fibers, particles, or large pieces from animal hair, nail, hoof, horn, or avian (e.g., poultry) feathers.

Abstract: The active part which is provided for use in a surge arrester includes two connecting fittings, which are arranged along an axis at a distance from one another, at least one cylindrical varistor column, which is provided between the two connecting fittings, and at least one dielectric loop. This loop is supported on the two connecting fittings and thus holds the active part together, thus forming a contact force. The active part is distinguished by a small physical height and little use of materials. This is achieved in that at least one of the two connecting fittings has an electrode, which is arranged at right angles to the axis and is in the form of a plate, as well as an electrical connection, which is integrally formed on the plate. Furthermore, supporting means which are in the form of shoulders are provided for the dielectric loop, and are formed in the plate and/or are integrally formed at the edge of the plate.

Abstract: A device for determining a hemoglobin quantity by inhaling a predetermined quantity of carbon monoxide as a bolus has a mouthpiece connected to a bag that can be filled with oxygen. The bag and the mouthpiece are connected via a connecting piece. The device is provided with a first valve for closing a first passage that links the connecting piece with the mouthpiece and a second valve for closing a second passage that links the connecting piece with the bag.

Abstract: Described is a method for stabilisation of nucleic acids by conctacting the nucleic acids with a polycationic polymer.

Abstract: A vaccine containing one or more synthetic or highly purified natural peptides or proteins as antigen(s) as well as one or more adjuvants is present in the form of a solution or emulsion which is free from inorganic salt ions or has a low concentration of salt ions. Preferably, it contains substances capable of making the vaccine isotonic, particularly sorbitol.

Abstract: Described is an immunostimulatory oligodeoxynucleic acid molecule (ODN) having the structure according to formula (I), wherein any X is O or S, any NMP is a 2′ deoxynucleoside monophosphate or monothiophosphate, selected from the group consisting of deoxyadenosine-, deoxyguanosine-, deoxyinosine-, deoxycytosine-, deoxyuridine-, deoxythymidine-, 2-methyl-deoxyinosine-, 5-methyl-deoxycytosine-, deoxypseudouridine-, deoxyribosepurine-, 2-amino-deoxyribosepurine-, -6-S-deoxyguanine-, 2-dimethyl-deoxyguanosine- or N-isopentenyl-deoxyadenosine-monophosphate or -monothiophosphate, NUC is a 2′ deoxynucleoside, selected from the group consisting of deoxyadenosine-, deoxyguanosine-, deoxyinosine-, deoxycytosine-, deoxyuridine-, deoxythymidine-, 2-methyl-deoxyinosine-, 5-methyl-deoxycytosine-, deoxypseudouridine-, deoxyribosepurine-, 2-amino-deoxyribosepurine-, 6-S-deoxyguanine-, 2-dimethyl-deoxyguanosine- or N-isopentenyl-deoxyadenosine, any X is O or S, a and b integers from 0 to 100 with the proviso that

Abstract: The electrical connecting element includes an essentially stiff core, essentially mechanically stiff and printed circuit boards and/or high density interconnects with conductor paths serving as interconnects. The core includes two parts (1, 3) that can be fixed to each other. Between the two parts, a cavity (101) can be formed. Components (103) producing a lot of heat or requiring protection from environmental influences can be placed in the cavity.

Abstract: The invention relates to the use of a polycationic compound for the preparation of a medicament for treating or preventing inflammation and for the preparation of a medicament with reduced inflammatory potential.

Abstract: The invention relates to the use of a polycationic compound for the preparation of a medicament with retarded in vivo release.

Abstract: The component with fault arc protection has an insulator in the form of a pillar, a first electrical conductor system which is provided on the insulator head and can be connected to high-voltage potential, and a second electrical conductor system which is provided on the insulator foot and can be connected to a ground potential. Each of the two electrical conductor systems contains an arcing electrode (7) for dissipating any fault arc which occurs in the event of a discharge between the two electrical conductor systems. The fault arc is dissipated particularly effectively if at least one of the two arcing electrodes (7) is in the form of a cup and has a cup base (12), which is attached to one electrical connection of the first or of the second electrical conductor system, as well as a cup wall (13) which is adjacent to the cup base (12) and extends predominantly in the direction of the axis (2) of the pillar.

Abstract: The apparatus is intended for disconnection of a live electrical conductor and has an enclosure (3) and two power connections (1, 2) which are passed out of the enclosure (3). A conductor section (7) which connects the two power connections (1, 2) to one another and a propellant means are arranged in the enclosure interior (4). The propellant means is used to produce an amount of compressed gas which is sufficient to disconnect the conductor section (7) when a fault current occurs. The propellant means is kept free of combustible substances and is chosen such that the amount of compressed gas which is required for disconnection can be thermally released from the propellant means by the electrical work produced by the fault current.

Abstract: Described is an immunostimulatory oligodeoxynucleic acid molecule (ODN) having the structure according to formula (I) 1

Abstract: The invention relates to a composition comprising

Abstract: The invention concerns methods for the production of micro-holes in semi-finished components (300) for printed circuit boards (200), consisting of several layers of electrically conductive materials (21,22) and dielectric materials (20), wherein micro-holes are embossed into dielectric materials and/or electrically conductive materials and that the embossed micro-holes are subsequently cleaned by means of plasma or by means of wet-chemical processes