Abstract: A process is provided of delivering at least one active agent cargo molecule into an neuronal cell whereby a cargo molecule is placed within a synthetic vesicle such as a liposome and a biotinylated protein such as an antibody is bound to the synthetic vesicle to form a protein bound synthetic vesicle whereby the protein recognizes a receptor expressed on the surface of a neuronal cell, and exposing the protein bound synthetic vesicle to the cell until the cargo molecule is delivered into the neuronal cell. Numerous cargo molecules are delivered by the inventive synthetic vesicle including a calpain inhibitor and a caspase inhibitor. The protein illustratively targets a cellular receptor for a ligand such as glutamate, glycine, dopamine, nicotine, muscarine, acetylcholine, or serotonin, and the like.

Abstract: A process for diagnosing and treating a neurological condition in a subject is provided that includes assaying a biological sample of a subject for the presence of one or more biomarkers; diagnosing a neurological condition based on a ratio of one or more of the biomarkers in the sample; and administering a therapeutic to the subject to alter the ratio of one or more biomarkers. The diagnosis numerous neurological conditions such as brain injury, or multiple organ injury is provided.

Abstract: A swing device for a grinding machine includes a motor located on a fixed table beside the sanding unit which includes a frame with two mandrels and a sanding belt is mounted to the two mandrels. A movable member is movably mounted to the shaft of the motor so as to move back and forth to activate two limit switches which are activated to stop the motor. The movable member is connected to a fixed plate connected to an end plate on the sanding unit and a link is connected between the fixed plate and an elongate slot of the movable member. The sanding unit together with the sanding belt swing when the movable member moves. The sanding belt swings and activates two micro switches to change the rotation direction of the shaft. The sanding belt swings to change the sanding portion contacting the objects to be polished.

Abstract: A flexible spike and ballistics panel having a strike surface and a rear surface. The panel contains a strike face grouping and a rear face grouping, where the normalized stiffness of each strike face layer is about 3 to 50 times greater than the normalized stiffness of each textile layer. The strike face grouping contains at least two strike face layers, each strike face layer having resin and high tenacity yarns, where the high tenacity yarns are in an amount of at least 50% by weight in each layer, where the high tenacity yarns have a tenacity of at least 5 grams per denier, and where the strike face grouping forms the strike surface of the panel. The rear face grouping contains at least ten layers of a spike resistant textile layer, each textile layer having a plurality of interwoven yarns or fibers having a tenacity of about 5 or more grams per denier, where at least one of the surfaces of the spike resistant textile layer contains about 10 wt.

Abstract: MicroRNAs are shown to be up- and/or down-regulated in inflammation and immune cells using a mouse model of asthma and regulatory T cells as source of RNA, respectively. Modulating the expression of these microRNAs can be effective in redirecting inflammation and immunity and hence, can be beneficial as biomarkers or as therapeutic agents against diverse human immunologic and inflammatory diseases.

Abstract: The present invention relates to a novel LPS-responsive and Beige-like Anchor gene (lrba), variants of the lrba gene, fragments of the lrba gene, and polypeptides encoded thereby. The subject invention also pertains to lrba interfering RNA, and uses thereof. In another aspect, the present invention also includes methods of inhibiting tumor growth in a patient by suppressing lrba function.

Abstract: Disclosed herein is a lateral flow immuno-assay system capable of rapidly, cost effectively, and quantitatively detecting and assessing the level of HIT antibodies in body fluids of a patient. Also taught are methods for employing the system to assist in diagnosis of HIT, and for screening or detecting a changing titer of HIT antibodies in the body fluids of a patient to determine susceptibility toward HIT.

Abstract: In a wobbling device of a sand belt grinder of the invention, a set of electromagnetic movable members is disposed outside a sand belt shaft base, and micro switches are disposed under two sides of the sand belt shaft base so that the control of continuously powering on and off is generated and the electromagnetic movable members generate continuously attracting and releasing operations. In addition, the movable members drive the shaft base and a sand belt to generate reciprocated wobbling operations at specific angles. Thus, when the sand belt is grinding, the sand belt generates the leftward and rightward sliding movement in a larger area so that the excellent polishing effect and the economic effectiveness can be obtained.

Abstract: A gear lever assembly for a car includes a gear lever, a support unit, a control unit and a power supply unit. The support unit includes a housing, a transparent body, a sphere, an electric wire, and an insulating member. The control unit is used to control operation of the sphere and the electric wire. The power supply unit is used to provide an electric power to the electric wire. The sphere produces a blink (or light) by operation of a high voltage static electricity. The insulating member is enclosed around the electric wire to prevent from incurring a static electricity leakage from the housing and the transparent body so as to prevent the static electricity from interfering with operation of the electronic systems in the car.

Abstract: The present invention provides a quick-assembly/disassembly mechanism for the sawblade cover of a wood sawing machine, which permits to install shields and stoppers correspondingly on both sides of a U-shaped supporting rod, and arrange a mobile damper within the supporting rod; moreover, when the quick-disassembly poker of the mobile damper is disassembled or assembled into the entire cover assembly, the poker is pulled up or pressed down to realize quick screwing and releasing of the cover assembly.

Abstract: The present invention relates to a novel LPS-responsive and Beige-like Anchor gene (lrba), variants of the lrba gene, fragments of the lrba gene, and polypeptides encoded thereby. The subject invention also pertains to lrba interfering RNA, and uses thereof. In another aspect, the present invention also includes methods of inhibiting tumor growth in a patient by suppressing lrba function.

Abstract: The present invention provides a reciprocating lifting motion of abrasive band grinding machine, wherein two control boxes are arranged correspondingly at lower part of the grinding mechanism of the grinding machine; the grinding mechanism is driven by the drive axle of the control box; a motor is coupled below the control box, and the control box is provided with a lifting mechanism, which is adapted with the cam via a main drive axle with worm gear; based on the eccentric rotation characteristic of the cam, the main drive axle could generate reciprocating lifting motion, driving the continuous operation of the grinding mechanism for uniform grinding of the abrasive band surface.

Abstract: A PCI Express system and a method of transitioning link state thereof. The PCI Express system includes an upstream component, a downstream component and a link. The upstream component and the downstream component transmit data to each other via the link. When at least one of the upstream component and the downstream component stops data transmission under a normal working state and if the system idle time period reaches a threshold idle time, then transiting the link into a second link state.

Abstract: The present invention provides an improved drive mechanism of the sawing machine for woodworking, which allows to install the integrated drive motor and sawing device onto the moveable mount of the fixed motor, so that the screw rod arranged at one side of two lifting rods enables lifting control to achieve most reliable lifting and stroke of entire saw blade set.

Abstract: An electronic device and a method for automatically converting text to be displayed on a display screen of an electronic device into a speech signal when ambient light conditions affect viewing of the text. The method is performed by the electronic device and the method includes receiving a command to display text on the display screen and determining if an ambient light signal provided by an ambient light sensor is above a pre-determined viewing threshold. This ambient light signal corresponds to ambient light conditions adjacent the display screen. The method also includes automatically converting the text to a speech signal when the ambient light signal is above the pre-determined viewing threshold. Suitably, there is performed a step of emitting the speech signal in an audible form from a speaker.

Abstract: The present invention provides a woodwork grinder, which can allow the grinding axle to be positioning quickly for replacement, so that the replacement can be carried out smoothly; it comprises a flexible insert rod on the grinding based of the grinding axle, and at least one insert slot on the side of the rotary axle of the grinding axle, so that the insert rod can be inserted into the insert slot when the rotary axle is stationary to position the rotary axle, and operators can use tools to assemble or disassemble the grinding axle so that the assembling/disassembling process can be carried out conveniently.

Abstract: The present invention provides a saw blade dismantling & positioning structure of sawing machine, whereby the push rod is snapped into the hole of the saw blade shaft disk for controlling the positioning of the rotating shaft and rapid dismantling the saw blade; a shaft disk is mounted onto the rotating shaft of the sawing machine, and at least a hole is preset laterally onto the shaft disk; a positioning device is assembled onto the lifting seat at the same side of the shaft disk; the pressure plate of the positioning device is driven so that the push rod is coupled and snapped into the hole of the shaft disk for controlling the positioning of rotating shaft, and rapid dismantling or assembly of the saw blade.

Abstract: The present invention provides a quick dismantling and positioning structure for the saw blade of sawing machine; a n-shaped rod is defined, two guard plates and stoppers are correspondingly arranged at both sides to form a shield assembly; moreover, two moveable dampers are arranged within the rod, a quick-release bolt is externally mounted onto the front end of the moveable clamper, so that the shield assembly could be quickly dismantled or reassembled by screwing and release of the quick-release bolt.

Abstract: The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury.

Abstract: In vivo determination of regional damage with neural and organ injury specific imaging agents. Rapid, and non-invasive imaging compositions and methods for assessment of the extent of neurotoxic cell loss or nervous system damage resulting from nervous system injury due to ischemia, stroke, trauma, chemical or electrical insult, acute drug overdose or exposure to substance abuse (such as “recreational drugs”) infection or other insults. The same or similar rapid, and non-invasive imaging compositions and methods for assessment of the extent of the organ injury comprises any damage, injury or infection, functional failure to specific organs such as liver, kidney, prostate, lung, skeletal muscle, heart, pancreas, stomach, small and large intestine, bladder and the reproductive system as well as damage, injury or infection, functional failure to multi-organs, trauma-hemorrhagic shock and sepsis.