Abstract: The present invention proposes a packer, comprising a central tube (1), an outer surface of which is provided with a first prefabricated groove (11); a rubber cylinder unit (2), comprising a rubber cylinder assembly (21), an upper rubber cylinder seat (22) and a lower rubber cylinder seat (23), a slot (221) being formed in an inner wall surface of the upper rubber cylinder seat; an upper anchoring unit (3) and a lower anchoring unit (4) arranged at both ends of the rubber cylinder unit, respectively, the upper anchoring unit comprising an upper cone (31) and an upper slip (32), and the lower anchoring unit comprising a lower cone (41) and a lower slip (42); and an unsetting mechanism (5), comprising a connecting sleeve (51), wherein through grooves (511) are arranged on the connecting sleeve, and one unsetting block (52) is arranged in each through groove.

Abstract: A portable shopping cart capable of serving as a seat includes a body part and a cloth pocket part. The body part is provided with a seat part. The body part includes a bottom supporting frame, a column supporting frame, a handle and wheels. A rotating positioning mechanism is arranged between the bottom supporting frame and the column supporting frame, and the rotating positioning mechanism is used for realizing rotation and support of the bottom supporting frame. The portable shopping cart realizes the functions of both a shopping cart and a seat, and can be transformed into a seat anytime and anywhere, and the handle can serve as the back of a chair, with high comfort. When not in use, the shopping cart can be folded for storage, so as to reduce the space of storage and transportation.

Abstract: The present disclosure discloses a sounding device including a frame, a vibration system mounted on the frame, including a diaphragm fixed to the frame and enclosing a front cavity with the frame; and a magnet system configured to drive the vibration system to generate sound, enclosing a rear cavity with the diaphragm and the frame; a connection hole is provided on the frame for connecting the front cavity with the rear cavity; an air-permeable membrane is inserted into the frame and covers the connection hole. The sounding device in the present disclosure has high assembly performance, waterproof performance and acoustic performance.

Abstract: Provided are a compound of Formula (I) and a pharmaceutical composition thereof, as well as a method for using the compounds of Formula (I) to prevent and/or treat immune-related disorders.

Abstract: The present invention proposes a packer, comprising a central tube (1), an outer surface of which is provided with a first prefabricated groove (11); a rubber cylinder unit (2), comprising a rubber cylinder assembly (21), an upper rubber cylinder seat (22) and a lower rubber cylinder seat (23), a slot (221) being formed in an inner wall surface of the upper rubber cylinder seat; an upper anchoring unit (3) and a lower anchoring unit (4) arranged at both ends of the rubber cylinder unit, respectively, the upper anchoring unit comprising an upper cone (31) and an upper slip (32), and the lower anchoring unit comprising a lower cone (41) and a lower slip (42); and an unsetting mechanism (5), comprising a connecting sleeve (51), wherein through grooves (511) are arranged on the connecting sleeve, and one unsetting block (52) is arranged in each through groove.

Abstract: Disclosed are a recombinant fusion protein derived from an HR region of an S2 protein of SARS-CoV-2 and an application of the recombinant fusion protein. The SARS-CoV-2 recombinant fusion protein is a recombinant fusion protein obtained by linking two membrane fusion-related conserved amino acid sequences HR1 and HR2 of the SARS-CoV-2 membrane protein S2 protein by means of a linking peptide. The recombinant fusion protein can be induced and expressed in Escherichia coli, has high expression quantity, and is easy to purify.

Abstract: The present invention belongs to the field of blood group antibody detection, and relates to use of a blood group antigenic trisaccharide conjugate in the blood group antibody detection, in particular to use of a blood group antigenic trisaccharide A analogue-protein conjugate and a blood group antigenic trisaccharide B analogue-protein conjugate in the blood group antibody detection. The blood group antigenic trisaccharide B analogue is conjugated to a keyhole limpet hemocyanin or a bovine serum albumin. When the blood group antigenic trisaccharide B analogue is a type B2, a conjugation ratio of the blood group antigenic trisaccharide B analogue to the keyhole limpet hemocyanin is 5:1-40:1, and a conjugation ratio of the blood group antigenic trisaccharide B analogue to the bovine serum albumin is 20:1.

Abstract: A deep neural network hardware accelerator comprises: an AXI-4 bus interface, an input cache area, an output cache area, a weighting cache area, a weighting index cache area, an encoding module, a configurable state controller module, and a PE array. The input cache area and the output cache area are designed as a line cache structure; an encoder encodes weightings according to an ordered quantization set, the quantization set storing the possible value of the absolute value of all of the weightings after quantization. During the calculation of the accelerator, the PE unit reads data from the input cache area and the weighting index cache area to perform shift calculation, and sends the calculation result to the output cache area. The accelerator uses shift operations to replace floating point multiplication operations, reducing the requirements for computing resources, storage resources, and communication bandwidth, and increasing the calculation efficiency of the accelerator.

Abstract: The present disclosure discloses a sounding device including a frame, a vibration system mounted on the frame, including a diaphragm fixed to the frame and enclosing a front cavity with the frame; and a magnet system configured to drive the vibration system to generate sound, enclosing a rear cavity with the diaphragm and the frame; a connection hole is provided on the frame for connecting the front cavity with the rear cavity; an air-permeable membrane is inserted into the frame and covers the connection hole. The sounding device in the present disclosure has high assembly performance, waterproof performance and acoustic performance.

Abstract: The present invention provides a dual-purpose camper capable of being towed by a bicycle and manually, including vehicle frames and a bicycle beam; a pull rod is rotatably connected between the two vehicle frames; a front bracket and a rear bracket are rotatably connected between the front end and the rear end of one side of the vehicle frames opposite to the pull rod; a fixing rod is rotatably connected in a fixing block; and the top end of the fixing rod penetrates through and is slidably connected with a sliding rod. A stable triangular structure is formed by a supporting rod and a second connecting rod; and the downward pressure of the vehicle frames after heavy loading is supported. The direction can be rotated and adjusted arbitrarily by a fisheye bearing to ensure the stability and directional control in the towing process of a bicycle.

Abstract: The invention discloses a bulk acoustic wave resonator and a manufacturing method thereof, the bulk acoustic wave resonator comprising: an air gap arranged at the external of the effective piezoelectric region, the air gap being formed between the upper electrode and the piezoelectric layer and/or between the piezoelectric layer and the substrate, and covering the end part, proximal to the air gap, of the lower electrode or connecting to the end part of the lower electrode, wherein the air gap is provided with a first end proximal to the effective piezoelectric region, and at least a portion of the upper surface, starting from the first end, of the air gap is an arch-shaped upper surface. The bulk acoustic wave resonator of the present invention capable of increasing a quality factor (Q) and an effective electromechanical coupling coefficient (K2t,eff) and improving the electrostatic discharge (ESD) immunity.

Abstract: A folding wagon with a folding table is provided and includes a first main frame and a second main frame. Positions at front and rear ends of the bottom of the first main frame are respectively fixedly connected to front brackets, tops of the two front brackets are provided with a connecting rod, and each of the bottoms of the two front brackets is rotatably connected to a front caster. A brake assembly passes through and is arranged at a position between the bottoms of the two front brackets, and positions adjacent to the bottom of the first main frame are respectively rotatably connected to first outer frames. In the folding wagon, the detachable connecting rod is provided on the two front brackets, which can be freely modified. In the connected state, the two front casters are controlled to turn left or right at the same time by a handle.

Abstract: The present invention provides a dual-purpose camper capable of being towed by a bicycle and manually, including vehicle frames and a bicycle beam; a pull rod is rotatably connected between the two vehicle frames; a front bracket and a rear bracket are rotatably connected between the front end and the rear end of one side of the vehicle frames opposite to the pull rod; a fixing rod is rotatably connected in a fixing block; and the top end of the fixing rod penetrates through and is slidably connected with a sliding rod. A stable triangular structure is formed by a supporting rod and a second connecting rod; and the downward pressure of the vehicle frames after heavy loading is supported. The direction can be rotated and adjusted arbitrarily by a fisheye bearing to ensure the stability and directional control in the towing process of a bicycle.

Abstract: A folding wagon with a folding table is provided and includes a first main frame and a second main frame. Positions at front and rear ends of the bottom of the first main frame are respectively fixedly connected to front brackets, tops of the two front brackets are provided with a connecting rod, and each of the bottoms of the two front brackets is rotatably connected to a front caster. A brake assembly passes through and is arranged at a position between the bottoms of the two front brackets, and positions adjacent to the bottom of the first main frame are respectively rotatably connected to first outer frames. In the folding wagon, the detachable connecting rod is provided on the two front brackets, which can be freely modified. In the connected state, the two front casters are controlled to turn left or right at the same time by a handle.

Abstract: The present invention relates to a CSF1R inhibitor, and in particular to a highly active CSF1R inhibitor compound having the structure of formula (I). Said compound of the present invention has high inhibitory activity on CSF1R.

Abstract: Provided are a compound of Formula (I) and a pharmaceutical composition thereof, as well as a method for using the compounds of Formula (I) to prevent and/or treat immune-related disorders.

Abstract: In an embodiment, process for providing a secure remote workspace includes accessing, via a first client application, a remote desktop application. The process includes activating, within the remote desktop, a second client application to provide access to a task. The process includes obtaining user input in connection with executing the task, and transmitting user input information associated with the execution of the task to a server.