Abstract: The present application relates to devices and components including apparatus, systems, and methods to provide adaptive physical downlink control channel (PDCCH) monitoring. In particular, a unified signaling technique for adaptive PDCCH search space monitoring is descried. This signaling can indicate either one or a combination of the switching and skipping. In an example, the signaling includes multiple parts. In a first part, radio resource control (RRC) signaling is sent from the network to the device to configure the device for switching only, skipping only, or switching and skipping. In a second part, first DCI is sent from the network to the device to indicate the particular PDCCH monitoring configuration to use for the PDCCH search space monitoring. Thereafter, network sends second DCI in the relevant PDCCH search space, where this second DCI schedules traffic. The device performs blind decoding to determine the second DCI in order to exchange the traffic.

Abstract: Disclosed herein are RNA methyltransferase inhibitors and methods of using and making the same. The inhibitors may be used in a method for the treatment of a subject in need of a treatment for a cancer by administering an effective amount of the RNA methyltransferase inhibitor and an effective amount of a DNA damaging agent to the subject.

Abstract: A transducer for an ultrasonic scalpel, which comprises, from distal end to proximal end of a connecting feature, a fixing feature, a horn, a piezoelectric converting body, a rear-end ring, and a connecting member. By following a design principle of constraints in the parameter relationships between the piezoelectric converting body and the horn in the transducer, a transducer having both appropriate gain and stable performance can be achieved.

Abstract: An apparatus for downhole multi-dimensional imaging includes an acquisition unit configured to acquire a formation resistivity signal, an ultrasonic echo signal and an orientation signal regularly; a sector calculation unit configured to calculate, based on said orientation signal, a sector where a currently acquired signal is from; and a multi-dimensional imaging unit, configured to calculate, based on the signals acquired by the acquisition unit, data of resistivity, distance from a drilling tool to a borehole wall and ultrasonic echo amplitude, and distribute said data into all sectors for feature recognition and extraction, thus obtaining key features characterizing a current formation being drilled, said key features being transmitted to ground for guiding drilling process. The structural complexity and the length of the downhole imaging measurement instrument can be reduced, and feature recognition can be directly performed on the imaging data underground.

Abstract: Disclosed is use of 5?-androst-3?,5,6?-triol or an analogue, a deuterated compound or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for the treatment of cerebral small vessel disease in a patient. The cerebral small vessel disease is preferably cerebral microbleed. The cerebral microbleed is spontaneous cerebral microbleed, drug-related cerebral microbleed, or traumatic cerebral microbleed. The present invention demonstrates that these compounds significantly enhance the clearance of extravascular hemoglobin, and thus can be used to treat cerebral small vessel disease.

Abstract: Disclosed herein are Piezo1 agonists. Also disclosed herein are methods of stimulating tissue anabolism in a subject comprising administering an effective amount of a Piezo1 agonist and methods for chemically mimicking mechanical stimulation of a cell expressing Piezo1 comprising contacting a cell expressing Piezo1 with an effective amount of a Piezo1 agonist.

Abstract: Described herein are anti-CD20 antibodies, anti-CD37 antibodies, and mixtures thereof, as well as nucleic acids encoding these antibodies and mixtures, vectors comprising these nucleic acids, and host cells containing these nucleic acids and/or vectors. Further described herein are methods for making and using these antibodies, mixtures of antibodies, nucleic acids, and vectors. Uses include therapeutic uses to treat a variety of conditions including cancers.

Abstract: A solid heat carrier catalyst for thermal desorption of organic matter-contaminated soil and a method for preparing the same. A hollow alumina ball prepared by 3D printing is taken as a solid heat carrier, copper-nickel-vanadium composite oxide is taken as a catalytic active component, and vinyltriethoxysilane is taken as a masking agent. The ball has a diameter of 30 mm to 60 mm and a thickness of 1 mm to 2 mm. An outer surface of the ball is masked with the vinyltriethoxysilane; then the ball is pierced to make an inner surface thereof connected with the outside through channels; the ball is then immersed in a catalytic active component precursor solution; and finally, drying and calcination are performed to obtain the solid heat carrier catalyst for thermal desorption of organic matter-contaminated soil. This product is widely applicable to the field of thermal desorption of organic contaminants of soil.

Abstract: A display substrate and a display apparatus are provided. The display substrate includes a base substrate; sub-pixels arranged in an array and on the base substrate; data line groups on the base substrate; each data line group includes data lines, each of which is connected to one column of sub-pixels; data selectors on the base substrate and connected to the data line groups in a one-to-one correspondence; data lines in a same data line group are connected to a same data selector; and data selection signal lines, wherein different data selection signal lines output different data selection signals; and different data lines connected to a same data selector correspond to different data selection signal lines, respectively. The display panel provided may effectively reduce the resistance on the data selection signal lines, thereby reducing the delay of the data selection signals and further improving the charging uniformity of sub-pixels.

Abstract: A content delivery network (CDN) edge node scheduling method includes receiving, by a scheduling proxy server, a first request message from a terminal device, determining, based on a first Internet Protocol (IP) address and configuration information, a target CDN scheduling center corresponding to the first IP address, sending a second request message to the target CDN scheduling center when the target CDN scheduling center supports proxy scheduling setting, receiving the second IP address from the target CDN scheduling center, and sending a request response message to the terminal device to obtain delivery content from the target CDN edge node based on the second IP address.

Abstract: The present disclosure provides a shift register, a gate driving circuit, a display panel, and a driving method thereof. The shift register includes: an input circuit; an output circuit; a first control circuit configured to provide a potential of a first control signal terminal to a pull-down node, and provide a potential of a reference signal terminal to the pull-down node according to the potential of the pull-up node; and a second control circuit connected to the pull-down node, a second control signal terminal, the output signal terminal, and the reference signal terminal, wherein the second control circuit is configured to pull down a potential of the output signal terminal during a display phase under the control of a potential of the pull-down node and a potential of the second control signal terminal, and pull up the potential of the output signal terminal in a power-off phase.

Abstract: A method for use in a container cluster management entity is disclosed. The method comprises performing a container cluster scaling operation on cluster instance resources in a container cluster instance in response to at least one triggering condition.

Abstract: Disclosed herein are RNA methyltransferase inhibitors and methods of using the same. The inhibitors may be used in a method for the treatment of a subject in need of a treatment for a cancer by administering an effective amount of an RNA methyl-transferase inhibitor to the subject.

Abstract: A display panel includes a second substrate. The second substrate includes a second base substrate and a shielding layer, an array structure layer, an insulating layer and a reflective layer which are sequentially disposed on a second base substrate, the array structure layer includes gate lines; the shielding layer includes a plurality of groups of light shielding units sequentially arranged along a first direction, each group of the light shielding units includes a plurality of independent sub-light shielding units sequentially arranged along a second direction, the reflective layer includes a plurality of reflective units arranged in an array, the plurality of reflective units form a plurality of reflective rows and a plurality of reflective columns, a first space area is formed between adjacent reflective columns, and a second space area is formed between adjacent reflective rows forms.

Abstract: Disclosed is a multi-shaft pressurized rock mechanics tester, pertaining to the technical field of rock mechanics testing devices, comprising a base; the base is of an integral rectangular structure, and welded six vertical support plates symmetrically at the front and back ends, a -shaped bracket plate is horizontally welded at the top of the six vertical support plates (“” is a Chinese character, read as “Ri”), and a bracket plate is rotatably installed on the top section of the three rear vertical support plates, pressed against the -shaped bracket plate; the left and right sides of the base are symmetrically welded with four vertical bracing plates, an I-shaped installation plate is welded on the top of the four vertical bracing plates, four hydraulic cylinders are locked, fixed and hoisted on the bottom of the I-shaped installation plate with screws.

Abstract: A seat plate assembly for fixing a capacitor on a circuit board, including a base plate, a first guard plate, a second guard plate, a third guard plate, a fourth guard plate, a first reinforcing rib and a second reinforcing rib. The first guard plate, the second guard plate, the third guard plate and the fourth guard plate are provided spaced apart on an upper end surface of the base plate in sequence. The first reinforcing rib is configured to connect the first guard plate with the second guard plate. The second reinforcing rib is configured to connect the third guard plate with the fourth guard plate.

Abstract: Disclosed is a multi-shaft pressurized rock mechanics tester, pertaining to the technical field of rock mechanics testing devices, comprising a base; the base is of an integral rectangular structure, and welded six vertical support plates symmetrically at the front and back ends, a -shaped bracket plate is horizontally welded at the top of the six vertical support plates (“” is a Chinese character, read as “Ri”), and a bracket plate is rotatably installed on the top section of the three rear vertical support plates, pressed against the -shaped bracket plate; the left and right sides of the base are symmetrically welded with four vertical bracing plates, an I-shaped installation plate is welded on the top of the four vertical bracing plates, four hydraulic cylinders are locked, fixed and hoisted on the bottom of the I-shaped installation plate with screws.

Abstract: A shift register unit, a driving method, a drive circuit, and a display apparatus are disclosed. The shift register unit includes: a control circuit, which is configured to adjust signals of a first node and a second node according to an input signal end, a first control signal end, a second control signal end and a first reference signal end; a cascade circuit, which is configured to provide, according to the signal of the first node, a signal of a first cascade clock signal end to a cascade output end; and an output circuit, which is configured to provide, according to the signal of the first node, a signal of a control clock signal end to a drive output end, and provide, according to the signal of the second node, a signal of a second reference signal end to the drive output end.

Abstract: This disclosure relates to the field of video processing technologies. The method includes: receiving, by the media asset subsystem, an indication message, where the indication message is used to indicate to add a medium file corresponding to a second video stream to the target media asset medium; obtaining a content source medium of the target video based on the indication message; sending the content source medium of the target video to a transcoding subsystem, so that the transcoding subsystem generates the medium file corresponding to the second video stream, where first information of the second video stream is the same as first information of the first video stream, and the first information includes whether a key frame is an IDR frame and location information of the key frame; and receiving the medium file that corresponds to the second video stream and that is sent by the transcoding subsystem.

Abstract: A computer-implemented method for generating personalized audio data is disclosed. The computer-implemented method includes receiving user input data, wherein the user input data is at least one of text or audio. The computer-implemented method further includes segmenting the user input data into a set of sentences. The computer-implemented method further includes generating, for each sentence in the set of sentences, a voice image, wherein the voice image includes at least one pronunciation tag and wave line associated with a sentence. The computer-implemented method further includes modifying the user input data based, at least in part on, the wave line and pronunciation tag of the voice image.