Patents by Inventor Weihan Zhang

Weihan Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240092774
    Abstract: Providing heteraromatic compounds and uses thereof. In particular, providing heteraromatic compounds of formula (I), pharmaceutical compositions comprising same, methods for preparing same and uses thereof, wherein the variables are as defined in the description.
    Type: Application
    Filed: September 17, 2021
    Publication date: March 21, 2024
    Applicant: HUTCHISON MEDIPHARMA LIMITED
    Inventors: Wei-Guo SU, Weihan ZHANG, Haibin YANG
  • Publication number: 20240002388
    Abstract: It relates to pyrimidinone compounds and uses thereof. In particular, it relates to pyrimidinone compounds of formula (I), and the pharmaceutical compositions, the preparing methods and the uses thereof, wherein the variables are as defined in the description.
    Type: Application
    Filed: August 17, 2021
    Publication date: January 4, 2024
    Inventors: Wei-Guo SU, Weihan ZHANG, Wei DENG, Haibin YANG
  • Publication number: 20230174513
    Abstract: The present invention relates to novel amide compounds of formula (I), pharmaceutical compositions comprising same, methods for preparing same, and uses thereof, wherein the definition of each symbol is as described in the description.
    Type: Application
    Filed: March 29, 2021
    Publication date: June 8, 2023
    Inventors: Wei-Guo SU, Weihan ZHANG, Haibin YANG
  • Publication number: 20220315597
    Abstract: Tricyclic compounds and their use are provided. More specifically, tricyclic compounds, pharmaceutical compositions containing them, methods for preparing them, and their use in therapy are also provided.
    Type: Application
    Filed: June 5, 2020
    Publication date: October 6, 2022
    Inventors: Wei-Guo SU, Weihan ZHANG, Jinshui LI
  • Patent number: 11191798
    Abstract: Disclosed herein are extracts of Andrographis paniculata having highly concentrated active ingredients, preparation methods and medical use for treating autoimmunity and inflammatory disease.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: December 7, 2021
    Assignee: NUTRITION SCIENCE PARTNERS LIMITED
    Inventors: Wei-Guo Su, Xiong Li, Weihan Zhang, Bo Liu, Huaqing Cai, Zhilong Weng, Hongqiang Wang, Zhiyong Yu, Lei Jiang
  • Patent number: 10611777
    Abstract: This disclosure provides novel imidazopyridazine compounds of formula (I) and pharmaceutical acceptable salt thereof, pharmaceutical compositions containing them, a process for preparing them, and their practical effect in inhibiting PI3K and potential use in treating a disease responsive to inhibition of PI3K, for example, an inflammatory disease, autoimmune disease or cancer.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: April 7, 2020
    Assignee: HUTCHISON MEDIPHARMA LIMITED
    Inventors: Wei-Guo Su, Guangxiu Dai, Weihan Zhang, Wei Deng
  • Publication number: 20190240275
    Abstract: Disclosed herein are extracts of Andrographis paniculata having highly concentrated active ingredients, preparation methods and medical use for treating autoimmunity and inflammatory disease.
    Type: Application
    Filed: November 1, 2017
    Publication date: August 8, 2019
    Inventors: Wei-Guo Su, Xiong Li, Weihan Zhang, Bo Liu, Huaqing Cai, Zhilong Weng, Hongqiang Wang, Zhiyong Yu, Lei Jiang
  • Publication number: 20190127391
    Abstract: This disclosure provides novel imidazopyridazine compounds of formula (I) and pharmaceutical acceptable salt thereof, pharmaceutical compositions containing them, a process for preparing them, and their practical effect in inhibiting PI3K and potential use in treating a disease responsive to inhibition of PI3K, for example, an inflammatory disease, autoimmune disease or cancer.
    Type: Application
    Filed: December 20, 2018
    Publication date: May 2, 2019
    Inventors: Wei-Guo Su, Guangxiu Dai, Weihan Zhang, Wei Deng
  • Patent number: 9701680
    Abstract: The present invention relates to novel pyrimidine and pyridine compounds of formula (I) or a pharmaceutical acceptable salt thereof, wherein R1, R2, R3, R4, R5, X, Y and G are as defined in the description, to pharmaceutical compositions containing them, a process for preparing them, and their use in therapy of a disease responsive to inhibition of FGFR, for example, cancer.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: July 11, 2017
    Assignee: HUTCHISON MEDIPHARMA LIMITED
    Inventors: Wei-Guo Su, Weihan Zhang, Jinshui Li
  • Publication number: 20160193268
    Abstract: An extract of Andrographis particulata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysaccharides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
    Type: Application
    Filed: January 7, 2016
    Publication date: July 7, 2016
    Applicant: Nutrition Science Partners Limited
    Inventors: Jifeng DUAN, Zhiming MA, Xiaoqiang YAN, Weihan ZHANG, Tao WANG, Yu CAI
  • Publication number: 20160052926
    Abstract: The present invention relates to novel pyrimidine and pyridine compounds of formula (I) or a pharmaceutical acceptable salt thereof, wherein R1, R2, R3, R4, R5, X, Y and G are as defined in the description, to pharmaceutical compositions containing them, a process for preparing them, and their use in therapy of a disease responsive to inhibition of FGFR, for example, cancer.
    Type: Application
    Filed: March 15, 2013
    Publication date: February 25, 2016
    Inventors: Wei-Guo SU, Weihan ZHANG, Jinshui LI
  • Publication number: 20160024021
    Abstract: The present invention relates to novel pyrimidine and pyridine compounds of formula (I) or a pharmaceutical acceptable salt thereof, wherein R1, R2, R3, R4, R5, X, Y and G are as defined in the description, to pharmaceutical compositions containing them, a process for preparing them, and their use in therapy of a disease responsive to inhibition of FGFR, for example, cancer.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 28, 2016
    Inventors: Wei-Guo SU, Weihan ZHANG, Jinshui LI
  • Patent number: 9181264
    Abstract: Provided are certain fused heteroaryls, compositions thereof and methods of use therefor.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: November 10, 2015
    Assignee: Hutchison MediPharma Limited
    Inventors: Weiguo Su, Weihan Zhang, Haibin Yang
  • Patent number: 9168253
    Abstract: Provided are certain quinazoline compounds, compositions thereof and methods of use thereof. These quinazoline compounds can effectively inhibit the overexpression and/or overactivity of epidermal growth factor receptor (EGFR).
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: October 27, 2015
    Assignee: HUTCHISON MEDIPHARMA LIMITED
    Inventors: Weihan Zhang, Wei-Guo Su, Haibin Yang, Yumin Cui, Yongxin Ren, Xiaoqiang Yan
  • Patent number: 8946249
    Abstract: Compound of Formula A and pharmaceutically acceptable salts thereof and crystalline Forms I and II of Compound of Formula A! Also, methods for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods for their uses.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: February 3, 2015
    Assignee: Hutchison Medipharma Limited
    Inventors: Wei-Guo Su, Weihan Zhang, Hong Jia, Yumin Cui, Yongxin Ren, Yang Sai, Zhenping Wu, Wenji Li, Jiangyong Shao, Zhenping Tian
  • Patent number: 8901143
    Abstract: A compound of the following formula: wherein R1, R2, R3, R4, R5, T, U, V, X, Y, Z, G, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder, e.g., cancer or age-related macular degeneration, with such a compound.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: December 2, 2014
    Assignee: Hutchison MediPharma Enterprises Limited
    Inventors: Wei-Guo Su, Hong Jia, Weihan Zhang, Yumin Cui, Xiaoqiang Yan, Yongxin Ren, Jifeng Duan, Yang Sai
  • Publication number: 20140315846
    Abstract: An extract of Andrographis paniculata extract containing androgapholide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysaccharides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
    Type: Application
    Filed: July 1, 2014
    Publication date: October 23, 2014
    Inventors: Jifeng DUAN, Zhiming MA, Xiaoqiang YAN, Weihan ZHANG, Tao WANG, Yu CAI
  • Publication number: 20140200232
    Abstract: Compound of Formula A and pharmaceutically acceptable salts thereof and crystalline Forms I and II of Compound of Formula A! Also, methods for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods for their uses.
    Type: Application
    Filed: December 12, 2013
    Publication date: July 17, 2014
    Applicant: HUTCHISON MEDIPHARMA LIMITED
    Inventors: WEI-GUO SU, WEIHAN ZHANG, HONG JIA, YUMIN CUI, YONGXIN REN, YANG SAI, ZHENPING WU, WENJI LI, JIANGYONG SHAO, ZHENPING TIAN
  • Patent number: 8658658
    Abstract: Compound of Formula A and pharmaceutically acceptable salts thereof and crystalline Forms I and II of Compound of Formula A! Also, methods for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods for their uses.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: February 25, 2014
    Assignee: Hutchison MediPharma Limited
    Inventors: Wei-Guo Su, Weihan Zhang, Hong Jia, Yumin Cui, Yongxin Ren, Yang Sai, Zhenping Wu, Wenji Li, Jiangyong Shao, Zhenping Tian
  • Publication number: 20140004212
    Abstract: An extract of Andrographis paniculata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographotide, neoandrographolide, polysacchorides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
    Type: Application
    Filed: September 6, 2013
    Publication date: January 2, 2014
    Applicant: Nutrition Science Partners Limited
    Inventors: Jifeng DUAN, Zhiming MA, Xiaoqiang YAN, Weihan ZHANG, Tao WANG, Yu CAI