Patents by Inventor Weihan Zhang

Weihan Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • extract
    Patent number: 8557308
    Abstract: An extract of Andrographis paniculata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysacchorides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: October 15, 2013
    Assignee: Nutrition Science Partners Limited
    Inventors: Jifeng Duan, Zhiming Ma, Xiaoqiang Yan, Weihan Zhang, Tao Wang, Yu Cai
  • extract
    Patent number: 8557302
    Abstract: An extract of Andrographis paniculata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysacchorides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
    Type: Grant
    Filed: November 4, 2008
    Date of Patent: October 15, 2013
    Assignee: Nutrition Science Partners Limited
    Inventors: Jifeng Duan, Zhiming Ma, Xiaoqiang Yan, Weihan Zhang, Tao Wang, Yu Cai
  • Use of substituted quinazoline compounds in treating age-related macular degeneration
    Patent number: 8497372
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: July 30, 2013
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Wei-Guo Su, Weihan Zhang, Xiaoqiang Yan, Yumin Cui, Yongxin Ren, Jifeng Duan
  • FUSED HETEROARYLS AND THEIR USES
    Publication number: 20130190307
    Abstract: Provided are certain fused heteroaryls, compositions thereof and methods of use therefor.
    Type: Application
    Filed: September 15, 2011
    Publication date: July 25, 2013
    Inventors: Weiguo Su, Weihan Zhang, Haibin Yang
  • QUINAZOLINE COMPOUNDS
    Publication number: 20130172373
    Abstract: Provided are certain quinazoline compounds, compositions thereof and methods of use thereof. These quinazoline compounds can effectively inhibit the overexpression and/or overactivity of epidermal growth factor receptor (EGFR).
    Type: Application
    Filed: May 25, 2011
    Publication date: July 4, 2013
    Applicant: Hutchison Medipharma Limited
    Inventors: Weihan Zhang, Wei-Guo Su, Haibin Yang, Yumin Cui, Yongxin Ren, Xiaoqiang Yan
  • Quinazoline derivatives
    Patent number: 8426430
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, X, Y, and Z are defined herein. It also discloses a method of treating cancer with one of these compounds.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: April 23, 2013
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Weihan Zhang, Wei-Guo Su, Haibin Yang, Yumin Cui, Yongxin Ren, Xiaoqiang Yan
  • ANDROGRAPHIS PANICULATA EXTRACT
    Publication number: 20130023493
    Abstract: An extract of Andrographis paniculata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysacchorides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
    Type: Application
    Filed: September 11, 2012
    Publication date: January 24, 2013
    Applicant: HUTCHISON MEDIPHARMA ENTERPRISES LIMITED
    Inventors: Jifeng Duan, Zhiming Ma, Xiaoqiang Yan, Weihan Zhang, Tao Wang, Yu Cai
  • Pyrimidine derivatives
    Patent number: 8349859
    Abstract: A compound of the following formula: wherein R1, R2, R3, R4, R5, T, U, V, X, Y, Z, G, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder, e.g., cancer or age-related macular degeneration, with such a compound.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: January 8, 2013
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Wei-Guo Su, Hong Jia, Weihan Zhang, Yumin Cui, Xiaoqiang Yan, Yongxin Ren, Jifeng Duan, Yang Sai
  • COMPOUND, CERTAIN NOVEL FORMS THEREOF, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS FOR PREPARATION AND USE
    Publication number: 20120270889
    Abstract: Compound of Formula A and pharmaceutically acceptable salts thereof and crystalline Forms I and II of Compound of Formula A! Also, methods for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods for their uses.
    Type: Application
    Filed: November 23, 2010
    Publication date: October 25, 2012
    Inventors: Wei-Guo Su, Weihan Zhang, Hong Jia, Yumin Cui, Yongxin Ren, Yang Sai, Zhenping Wu, Wenji Li, Jiangyong Shao, Zhenping Tian
  • USE OF SUBSTITUTED QUINAZOLINE COMPOUNDS IN TREATING ANGIOGENESIS-RELATED DISEASES
    Publication number: 20120238572
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
    Type: Application
    Filed: June 4, 2012
    Publication date: September 20, 2012
    Inventors: Wei-Guo Su, Weihan Zhang, Xiaoqiang Yan, Yumin Cui, Yongxin Red, Jifeng Duan
  • Use of substituted quinazoline compounds in treating angiogenesis-related diseases
    Patent number: 8212033
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: July 3, 2012
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Wei-Guo Su, Weihan Zhang, Xiaoqiang Yan, Yumin Cui, Yongxin Ren, Jifeng Duan
  • Decahydronaphthalene compounds
    Patent number: 7902359
    Abstract: This invention relates to a compound of the following formula: wherein R1, R2, R3, G, and Z are defined herein. It also relates to is methods of treating autoimmune disease, cancer, and atherosclerosis with such a compound.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: March 8, 2011
    Assignee: Hutchison MediPharma Enterprises Limited
    Inventors: Tao Wang, Weihan Zhang, Xiaoqiang Yan, Weiguo Su, Jifeng Duan, Yu Cai
  • QUINAZOLINE DERIVATIVES
    Publication number: 20110015213
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
    Type: Application
    Filed: September 29, 2010
    Publication date: January 20, 2011
    Inventors: Wei-Guo Su, Weihan Zhang, Xiaoqiang Yan, Yumin Cui, Yongxin Ren, Jifeng Duan
  • Substituted quinazoline compounds and their use in treating angiogenesis-related diseases
    Patent number: 7829574
    Abstract: Substituted quinazoline compounds of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, and X are defined herein. It also discloses a pharmaceutical composition containing one of these compounds.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: November 9, 2010
    Assignee: Hutchison MediPharma Enterprises Limited
    Inventors: Wei-Guo Su, Weihan Zhang, Xiaoqiang Yan, Yumin Cui, Yongxin Ren, Jifeng Duan
  • QUINAZOLINE DERIVATIVES
    Publication number: 20100009958
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, X, Y, and Z are defined herein. It also discloses a method of treating cancer with one of these compounds.
    Type: Application
    Filed: June 30, 2008
    Publication date: January 14, 2010
    Applicant: Hutchison MediPharma Enterprises Limited
    Inventors: Weihan Zhang, Wei-Guo Su, Haibin Yang, Yumin Cui, Yongxin Ren, Xiaoqiang Yan
  • Andrographolide and analogues as inhibitors of TNF? and IL-1? expression
    Patent number: 7625945
    Abstract: This invention relates to a method of inhibiting the expression of TNF? or IL-1? with a compound of the following formula: wherein R1 and R2 are defined herein. It also relates to is a method of treating inflammatory bowel disease with such a compound.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: December 1, 2009
    Assignee: Hutchison MediPharma Enterprises Ltd.
    Inventors: Xiaoqiang Yan, Tao Wang, Zhiming Ma, Ke Pan, Weihan Zhang, Jianrong Hong, Jeff Duan, Yu Cai
  • Costunolide derivatives
    Patent number: 7622465
    Abstract: Disclosed are methods for inhibiting TNF? expression, IL-1? expression, iNOS expression, and NF-?B activity and methods for treating autoimmune disease, cancer, or atherosclerosis with a compound of the following formula:
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: November 24, 2009
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Wei-Guo Su, Hong Jia, Xiaoqiang Yan, Jifeng Duan, Tao Wang, Yu Cai, Weihan Zhang
  • QUINAZOLINE DERIVATIVES
    Publication number: 20090281130
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
    Type: Application
    Filed: May 9, 2008
    Publication date: November 12, 2009
    Applicant: Hutchison Medipharma Enterprises Limited
    Inventors: Wei-Guo Su, Weihan Zhang, Xiaoqiang Yan, Yumin Cui, Yongxin Ren, Jifeng Duan
  • Crude extracts from andrographis paniculata
    Patent number: RE42718
    Abstract: This invention relates to a method of inhibiting TNF? or IL-1? expression with an extract of Andrographis paniculata. The extract contains andrographolide, 14-deoxy-andrographolide, 14-deoxy-11,12-dehydrogen-andrographolide, and neoandrographolide.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: September 20, 2011
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Xiaoqiang Yan, Tao Wang, Zhiming Ma, Weihan Zhang, Jifeng Duan, Yu Cai
  • Crude extracts from
    Patent number: RE43423
    Abstract: This invention relates to a method of inhibiting TNF? or IL-1? expression with an extract of Andrographis paniculata. The extract contains andrographolide, 14-deoxy-andrographolide, 14-deoxy-11,12-dehydrogen-andrographolide, and neoandrographolide.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: May 29, 2012
    Assignee: Hutchison MediPharma Enterprises Limited
    Inventors: Xiaoqiang Yan, Tao Wang, Zhiming Ma, Weihan Zhang, Jifeng Duan, Yu Cai