Abstract: A method of manufacturing a die package structure includes steps described below. A conductive substrate with a plurality of trenches is provided. A die is disposed in each of the trenches. A conductive layer is formed covering the dies and the conductive substrate. A patterned photoresist layer with a plurality of openings is formed exposing a plurality of areas of the conductive layer. A mask is formed on each of the areas of the conductive layer. The patterned photoresist layer is removed after forming the masks. By using the masks, the conductive layer and the conductive substrate under thereof are selectively etched to a predetermined depth to form a plurality of conductive bumps and a plurality of electrodes, in which a remaining of the conductive substrate includes a bottom substrate, the electrodes and the conductive bumps. An upper sealing layer is formed covering the bottom substrate and the dies.

Abstract: A package structure and method for forming the same are provided. The package structure includes a first interconnect structure formed over a first substrate, and the first interconnect structure includes a first metal layer. The package structure further includes a second interconnect structure formed over a second substrate. The package structure includes a bonding structure between the first interconnect structure and the second interconnect structure. The bonding structure includes a first intermetallic compound (IMC) and a second intermetallic compound (IMC), a portion of the first IMC protrudes from the sidewall surfaces of the second IMC, and there could be a grain boundary between the first IMC and the second IMC.

Abstract: Drug delivery devices comprising a non-bioabsorbable polymer structure configured to support a composition comprising an active agent. The devices include a plurality of portions fused together and a recess configured to support the composition. At least one of the portions includes an impermeable polymer and at least one other portion includes a rate-limiting water-permeable polymer. The rate-limiting water-permeable polymer allows for transportation of the active agent to an exterior of the device.

Abstract: A method forming a gate dielectric over a substrate, and forming a metal gate structure over the semiconductor substrate and the gate dielectric. The metal gate structure includes a first metal material. The method further includes forming a seal on sidewalls of the metal gate structure. The method further includes forming a dielectric film on the metal gate structure, the dielectric film including a first metal oxynitride comprising the first metal material and directly on the metal gate structure without extending over the seal formed on sidewalls of the metal gate structure.

Abstract: Described herein are compounds and compositions for treating glaucoma and/or reducing intraocular pressure. Compositions may comprise an isoquinoline compound and a prostaglandin or a prostaglandin analog. Compounds described herein include those in which an isoquinoline compound is covalently linked to a prostaglandin or a prostaglandin analog, and those in which an isoquinoline compound and a prostaglandin free acid together form a salt.

Abstract: A first provider edge device may receive device information from a second provider edge device included in an Ethernet virtual private network (EVPN). The device information may identify a media access control (MAC) address and may indicate that the device is connected to the second provider edge device. The first provider edge device may receive data transmitted by the device and may determine, based on information included in the data, that the device has moved from the second provider edge device to the first provider edge device. The first provider edge device may generate a data packet including mobility information indicating that the device has moved to the first provider edge device. The first provider edge device may transmit, via a data plane of the EVPN, the data packet to the second provider edge device to permit the second provider edge device to update routing information for the device.

Abstract: A physiological detection device includes system including a first array PPG detector, a second array PPG detector, a display and a processing unit. The first array PPG detector is configured to generate a plurality of first PPG signals. The second array PPG detector is configured to generate a plurality of second PPG signals. The display is configured to show a detected result of the physiological detection system. The processing unit is configured to convert the plurality of first PPG signals and the plurality of second PPG signals to a first 3D energy distribution and a second 3D energy distribution, respectively, and control the display to show an alert message.

Abstract: Described herein are compounds and compositions for treating glaucoma and/or reducing intraocular pressure. Compositions may comprise an isoquinoline compound and a prostaglandin or a prostaglandin analog. Compounds described herein include those in which an isoquinoline compound is covalently linked to a prostaglandin or a prostaglandin analog, and those in which an isoquinoline compound and a prostaglandin free acid together form a salt.

Abstract: A light-emitting diode (LED) chip is provided. The LED chip includes a first semiconductor layer, a second semiconductor layer, a first electrode electrically connected with the first semiconductor layer, and a second electrode electrically connected with the second semiconductor layer. The first electrode is in an annular shape and surrounds the second electrode. The first electrode and the second electrode cooperate to define a first channel therebetween. The first channel is in an annular shape. The first electrode defines at least one second channel therein. The at least one second channel extends through an inner side and an outer side of the first electrode and communicates with the first channel. A communication between the first channel and the second channel facilitates solder volatiles during soldering the LED chip, and potential short circuits can be further avoided. A display panel and an electronic device are further provided.

Abstract: An extreme ultraviolet (EUV) mask is received. The EUV mask has an EUV pellicle disposed thereover. The EUV pellicle is coupled to the EUV mask at least in part via glue that is disposed on the EUV mask. The EUV pellicle is removed, thereby exposing the glue. A localized glue-removal process is performed by targeting a region of the EUV mask on which the glue is disposed. The localized glue-removal process is performed without affecting other regions of the EUV mask that do not have the glue disposed thereon. The localized glue-removal process may include injecting a cleaning chemical onto the glue and removing a waste chemical produced by the cleaning chemical and the glue. The localized glue-removal process may also include a plasma process that applies plasma to the glue. The localized glue-removal process may further include a laser process that shoots a focused laser beam at the glue.

Abstract: The invention provides a novel class of propiolylamide-based irreversible inhibitors of PKM2 compounds of the general formula I, pharmaceutical compositions, and methods of inducing an anti-tumor effect in a subject suffering from tumor comprising administering to the subject a pharmaceutical composition comprising an effective amount of compound of formula I.

Abstract: An electronic device includes a host, a display, a sliding plate, and a keyboard. The host has an operating surface. The display is pivoted to the host. The sliding plate is slidably disposed in the host, where the display is mechanically coupled to the sliding plate, and the sliding plate includes a plat portion and a recess portion that are arranged side by side. The keyboard is integrated to the host. The keyboard includes a key structure, where the key structure includes a key cap and a reciprocating element, and the key cap is exposed from the operating surface of the host. The reciprocating element is disposed between the key cap and the sliding plate and has a first end connected to the key cap and a second end contacting the sliding plate. The second end is located on a sliding path of the plat portion and the recess portion.

Abstract: In the present invention, an anti-pinch device which uses a simple optical mechanism to prevent the user being hurt by the moving part before the moving part touches the user is disclosed. Also, a space computing device which uses a simple optical mechanism to compute acquired space of a target object is disclosed. Additionally, a hovering control device which uses a simple optical mechanism thereby the user can control the hovering control device without touching the hovering control device is disclosed. The optical mechanism comprises at least one light source and at least one optical sensor, which can arrange in various ways.

Abstract: A device for generating a security key includes a substrate, semiconductor units, contact structures, and defects. The semiconductor units are disposed on the substrate. The contact structures are disposed on and connected with the semiconductor units. The defects are disposed in at least a part of the contact structures randomly. A manufacturing method of a device for generating a security key includes the following steps. First semiconductor units are formed on a substrate. First contact structures are formed on the first semiconductor units. The first contact structures are connected with the first semiconductor units, and defects are formed in at least a part of the first contact structures randomly.

Abstract: The present invention provides a Bifidobacterium lactis having active substances, a composition comprising the same, and a method of promoting longevity using the same by subjecting the composition to a subject, thereby increasing Cisd2 gene expression, reducing damage of mitochondria, delaying aging-related symptoms including nerve degeneration and sarcopenia, and so on.

Abstract: A method for micro-LED epitaxial wafer manufacturing and a micro-LED epitaxial wafer are provided. The method includes the following. For each growth region of a micro-LED chip on a growth substrate, photoresist is applied to the growth region. For each growth region, an epitaxial isolation wall is grown at a boundary of the growth region. For each growth region, the photoresist on the growth substrate is removed with the epitaxial isolation wall remained. For each growth region, a first semiconductor layer, a light-emitting layer, and a second semiconductor layer are grown in the growth region to obtain a micro-LED epitaxial structure. The growth substrate is cut along the epitaxial isolation wall, to obtain at least two micro-LED epitaxial structures.

Abstract: A light emitting diode (LED) chip and a method for manufacturing an LED chip are provided. The LED chip includes a sapphire layer, an N-type semiconductor layer, a light emitting layer, a P-type semiconductor layer, a P electrode, and an N electrode. The N-type semiconductor layer, the light emitting layer, the P-type semiconductor layer, the P electrode are sequentially disposed on a surface of the sapphire layer. The sapphire layer defines multiple preset patterns which extend through the sapphire layer, and the multiple preset patterns are used for reflecting a light of a preset wavelength through a channel defined by the sapphire layer.

Abstract: The problem of looping at the egress of a transport network with a CE multihomed to a protected egress PE and a backup/protector egress PE can be avoided by (a) enabling the protector egress PE to distinguish between fast reroute (FRR) traffic coming from the protected egress PE and normal known unicast (KU) traffic coming from a PE of the transport network that is not attached to the same multihomed segment; (b) receiving, by the protector egress PE, known unicast data, to be forwarded to the CE; (c) determining, by the protector egress PE, that a link between it and the CE is unavailable; and (d) responsive to determining that the link between the protector egress PE and the CE is unavailable, (1) determining whether the known unicast traffic received was sent from the protected egress PE or from another PE of the transport network that is not attached to the same multihomed segment, and (2) responsive to a determination that the known unicast traffic received was sent from the protected egress PE, discardi

Abstract: For use in an Ethernet Virtual Private Network (EVPN) in which a site including at least one MAC-addressable device is multihomed, via a customer edge device (CE), to at least two provider edge devices (PE1 and PE2), the potential problem of one of the at least two provider edge devices (PE2) dropping or flooding packets designed for a MAC-addressable device of the multihomed site is solved by controlling advertisements of an auto-discovery per EVPN instance (A-D/EVI) route (or an auto-discovery per Ethernet segment identifier (A-D/ESI) route) to a remote provider edge device (PE3), belonging to the EVPN but not directly connected with the CE.