Abstract: (I) Disclosed herein are compounds of formula I, and/or a stereoisomer, a stable isotope, or a pharmaceutically acceptable salt or solvate thereof; and therapeutic uses of these compounds, which are inhibitors of rearranged during transfection (RET), potentially useful in the treatment of RET-associated diseases, such as RET-associated cancers.

Abstract: A voltage control circuit is configured to connected to a display panel, the display panel includes a plurality of pixels, the plurality of pixels includes a first pixel and a second pixel, and the first pixel and the second pixel are pixels corresponding to different colors. The voltage control circuit is configured to provide a first voltage to the first pixel and a second voltage to the second pixel at a first time and a second time, respectively; the first voltage provided at the first time is different from the second voltage provided at the first time, and the first voltage provided at the second time is identical with the second voltage provided at the second time.

Abstract: Apparatuses and methods for focusing a camera are disclosed. For example, an apparatus may be coupled to a camera for focusing the camera. The apparatus includes a vision sensor coupled to a processor and configured to capture a view. The processor configured to receive a selection of an area of interest in the view. The apparatus further includes a distance measurement unit coupled to the processor and configured to measure a distance to the area of interest for adjusting the camera's focus.

Abstract: The invention relates to an aqueous agrochemical composition comprising a) suspended particles of an active ingredient; and b) lignosulfonate. It also relates to use of the lignosulfonate for stabilizing an aqueous agrochemical composition comprising suspended particles of the active ingredient. Further objects are a method of stabilizing an aqueous agrochemical composition comprising suspended particles of an active ingredient; a method for treating, controlling pre-venting or protecting animals against infestation or infection by parasites; a method for the preparation of the agrochemical composition; and plant propagation material comprising the agrochemical composition.

Abstract: The invention relates to an aqueous agrochemical composition comprising a) suspended particles of an active ingredient; and b) hydrophobically modified fumed silica. It also relates to use of the hydrophobically modified fumed silica for stabilizing an aqueous agrochemical composition comprising suspended particles of an active ingredient; to a method of stabilizing an agrochemical composition comprising the suspended particles of an active ingredient; to a method for treating, controlling, preventing or protecting animals against infestation of infection by parasites by application of the agrochemical composition; to a method of preparing the agrochemical composition; and to plant propagation material containing the agrochemical composition.

Abstract: The invention relates to an aqueous agrochemical composition comprising a) suspended particles of an active ingredient; and b) ethoxylated ricinolein; wherein the active ingredient has a water-solubility of at least 1 g/l at 25° C.; and wherein the ethoxylated ricinolein contains 35 to 50 molecules of ethylene oxide per molecule of ricinolein in polymerized form. It also relates to a method of stabilizing an aqueous agrochemical composition comprising the suspended particles of the active ingredient; to uses and methods of application of the agrochemical composition; and to a method for preparing the agrochemical composition; and to plant propagation material comprising the agrochemical composition.

Abstract: The present disclosure provides a load stabilization device, a control method thereof, and a computer readable storage medium. In the load stabilization device, a motion sensor, a processor, a stabilization motor, and a parallelogram mechanism constitute a closed-loop feedback control system.

Abstract: A method, system, and computer program product for detecting and monitoring a signal is provided. The method includes detecting an alignment point for a periodic signal segment of a periodic signal generated by an apparatus being monitored for standard functionality In response, the apparatus is activated from a period prior to the alignment point to an end point of the periodic signal segment and a first point of the periodic signal segment is located. Likewise, a second point of an additional periodic signal segment of the periodic signal is located. The periodic signal is normalized based on results of locating the first point and the second point.

Abstract: A method for positioning an underwater glider based on a virtual TDOA of a single beacon is provided. In the method, a positioning beacon periodically sends positioning messages, where the positioning message includes longitude, latitude and depth information of the positioning beacon; the underwater glider receives the positioning messages and records TOAs at which the positioning messages arrive at an acoustic positioning signal receiving module; and the underwater glider parses the positioning messages and stores positioning message data, creates virtual beacons based on beacon information and attitude information of the underwater glider, corrects the TOAs, and calculates a position of the underwater glider according to a TDOA algorithm. According to the method, the underwater glider passively listens to and receives the positioning messages without sending a positioning request to the positioning beacon, making the entire positioning process energy-saving with a certain degree of concealment.

Abstract: Apparatuses and methods for focusing a camera are disclosed. For example, an apparatus may be coupled to a camera for focusing the camera. The apparatus includes a vision sensor coupled to a processor and configured to capture a view. The processor configured to receive a selection of an area of interest in the view. The apparatus further includes a distance measurement unit coupled to the processor and configured to measure a distance to the area of interest for adjusting the camera's focus.

Abstract: A series of peptides and a peptide-siRNA complex are disclosed, wherein the peptide based complex effectively enhances delivery of siRNA molecules into the cells and release of siRNA in the cell, and improves siRNA mediated gene silencing efficiency of cellular targets. Pharmaceutical compositions that include the complex, as well as a use of the complex in the gene therapy field, are also disclosed.

Abstract: Protograph-based LDPC codes are obtained from z-row-orthogonal base matrices with some additional structure constraints, such as a diagonal and/or double-diagonal structure, in order to allow a high parallelization that is a multiple of z, while having an efficient encoding or decoding. A “big” base matrix is constructed from a structured square submatrix in order to have a WiMAX-like structure and a z-row-orthogonality. Also, starting from a “smaller” base matrix having a part arranged in a double-diagonal shape with tail-biting one, an expansion by a factor equal to z can be performed, followed by an addition of a single one-entry into the last column at a specific location, thereby obtaining a three-degree column, and followed by a row and/or column permutation in order to obtain a base matrix in a WiMAX-like structure.

Abstract: The invention relates to an agrochemical composition comprising propylene carbonate, up to 10 wt % of water, and compounds I their salts, tautomers, or enantiomers; wherein the variables are as defined in the description. The invention also relates to a process for the preparation of the composition, comprising mixing the propylene carbonate, compounds I, and optionally an acid and/or cyclohexanone. It also relates to a method for controlling pests, which method comprises the application of the composition, or a dilution thereof, to plants, plant propagation material, or the locus of growth of the plants; the pests or their food supply, habitat or breeding grounds. Other objects are the use of cyclohexanone and/or an acid, in particular acetic acid, for stabilizing compositions comprising compounds I; composition for stabilizing water-soluble pesticides as defined in any of claims 1 to 9, comprising 1 to 50 wt % of propylene carbonate, 0.

Abstract: Provided herein is a method for reducing resistance in an individual having a drug resistant cancer, for example, a BRAF inhibitor resistant cancer. A Hippo signaling pathway inhibitor such as a Yes-associated protein 1 (YAP1) inhibitor, a Transcriptional Coactivator with PDZ-binding motif (TAZ) inhibitor, a Transcription enhancer domain (TEAD) inhibitor or a combination of these is administered. Also provided is a method of treating BRAF inhibitor resistance in an individual with a BRAF inhibitor resistant cancer, for example, malignant melanoma, with a Hippo signaling pathway inhibitor, such as Verteporfin, and a BRAF inhibitor.

Abstract: (I) Disclosed herein are compounds of formula I, and/or a stereoisomer, a stable isotope, or a pharmaceutically acceptable salt thereof; and therapeutic uses of these compounds, which are kinase inhibitors potentially useful in the treatment of diseases treatable, such as cancers, as well as pharmaceutical compositions, comprising a compound of formula I, and/or a stereoisomer, a stable isotope, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.

Abstract: The present application discloses is a scheduling method and system for fully autonomous waterborne inter terminal transportation, and belongs to the field of transportation. The method includes: establishing a dynamic scheduling model for waterborne Autonomous guided vessels (wAGVs); quickly inserting the dynamically arriving transportation tasks into all the existing wAGV paths, calculating the insertion cost and selecting the path and position with the lowest insertion cost to obtain updated initial paths; improving the initial path using a heuristic algorithm based on tabu search to obtain quasi-optimal wAGV paths; executing the scheduling wAGV paths. The scheduling model of the present application is based on the combinatorial optimization, and considers performance indexes such as transportation distance and customer satisfaction, and constraints such as time window and loading capacity. An initial path by using an insertion method within the framework of rolling horizon is constructed.

Abstract: The present invention relates to a novel crystalline form of 1-(1,2-dimethylpropyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide recently assigned the common name dimpropyridaz. The invention also relates to the use of the crystalline form B for combating invertebrate pests and to formulations for plant protection which contain the crystalline form B of 1-(1,2-dimethylpropyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide. The crystalline form B according to the present invention can be identified by powder X-ray diffractometry on the basis of its powder X-ray diffraction diagram, hereinafter also termed powder X-ray diffraction pattern or PXRD pattern, of the polymorph form B recorded using Cu—K? radiation (1.54178 ?) at 25° C. displays the 3 following reflections, quoted as 2? values: 20.69±0.10°, 24.15±0.10° and 30.52±0.10°.

Abstract: In an embodiment, a radio resource manager device is provided. The radio resource manager device may include a receiver configured to receive an application applying for radio resources; an interference allowance determiner configured to determine whether interference of signal transmission during radio communication using radio resources is allowed; and a radio resource assigner configured to assign radio resources based on the determined interference allowance.

Abstract: A display device includes a controller, a frame, a display panel, an FPC and a force sensing structure; wherein the FPC is disposed on a back side of the display panel and electrically connected to the display panel, and the back side of the display panel is a side opposite to a light-emitting surface of the display panel; the force sensing structure is disposed on the FPC and electrically connected to the controller by the FPC; and the frame is disposed on a side, distal from the display panel, of the FPC, and a specified distance exists between the frame and the force sensing structure.

Abstract: Example transmission methods and apparatus are described. In one example method, a transmitter is configured to communicate with a receiver via a communication channel. The transmitter is configured to precode a data word into a precoded data word using a probabilistic shaping scheme, wherein the probabilistic shaping scheme depends on one or more precoding parameters. The precoded data word is encoded into a codeword using a modulation and/or coding scheme, wherein the modulation and/or coding scheme depends on one or more modulation and coding parameters. At least one precoding parameter is determined on the basis of at least one of the one or more modulation and coding parameters and/or on the basis of at least one further precoding parameter.