Abstract: The invention relates to (among other things) oligomer-PTK inhibitor conjugates and related compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits advantages over PTK inhibitor compounds lacking a water-soluble, non-peptidic oligomer.

Abstract: A cooling system for computer, a cooling apparatus and a cooling method are described. The cooling system includes a computer casing, a fan and the fan-less cooling apparatus. The fan-less cooling apparatus has an air passage with two open ends and a closed circumference. The air passage passes a heat dissipating part of the apparatus, one end of the air passage communicates with air outside the computer casing and the other end communicates with air inside the computer casing. a plurality of blowholes for the fan and the air passage are formed in the computer casing. There is at least one fan. Air is blown inside or outside through the blowholes, which causes a pressure difference between the interior and the exterior of the computer casing. The pressure difference leads an air flow to flow through the blowholes to dissipate heat.

Abstract: Disruption of mitogen inducible gene 6 (Mig-6) in mice by homologous recombination (KO mice) led to early onset osteoarthritis (OA) as revealed by simultaneous enlargement and deformity of multiple joints, degradation of articular cartilage and the development of bony outgrowths or osteophytes within the joint space. Because of the striking similarity to human OA, Mig-6 KO mice are a useful animal model for studying the mechanism of this disease and for testing new drugs or therapies for treating OA. These KO mice also developed epithelial hyperplasia, adenoma, and adenocarcinoma in organs such as lung, gallbladder, and bile duct. Mig-6 is therefore a tumor suppressor gene and is a candidate gene for the frequent Ip36 genetic alterations found in lung cancer. It can be used as a tumor biomarker as well as a target for cancer therapy.

Abstract: A hand operated puppet includes a pair of characters that are interconnected such that when the first character is in a display orientation the other character is in a storage orientation inside the first character. The head of one character is shaped and dimensioned to compressibly store the head of the other character. The head of each character includes an elastic, resilient foam insert shaped and dimensioned to conform to the contour of the face of the character.

Abstract: The invention provides antihistamine drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the antihistamine drug not attached to the water-soluble oligomer.

Abstract: A die seal ring disposed outside of a die region of a semiconductor substrate is disclosed. The die seal ring includes a first isolation structure, a second isolation structure, and at least one third isolation structure disposed between the first isolation structure and the second isolation structure; a plurality of first regions between the first isolation structure, the second isolation structure and the third isolation structure; a second region under the first region and the third isolation structure; and a third region under the first isolation structure.

Abstract: Provided herein is a straightforward and efficient method for covalently attaching a polyethylene glycol polymer to docetaxel. The method involves, among other things, a step of reacting docetaxel with a polyethylene glycol polymer comprising a functional group reactive with a hydroxyl group within docetaxel in the presence of a coupling reagent and DPTS. The result of the reacting step is the formation of a polyethylene glycol-docetaxel conjugate having a single polyethylene glycol covalently attached, via an ester linkage, to the hydroxyl group within docetaxel.

Abstract: A USB converter circuit for converting electrical signals from a key scan circuit (in PS/2 or other formats) into USB signals for a computer while supporting N-key rollover (NKRO) functions. The converter circuit can be implemented as a stand-alone PS/2 to USB keyboard converter or as an integral component of a USB keyboard or KVM switch. The converter circuit includes a converter module that generates keyboard data packets in the USB format having a 16-byte, 64-byte, etc. format representing key press information for up to 8 modifier keys and 14, 62, etc. non-modifier keys, respectively. The converter circuit also includes a USB device controller module which transmits the 16-byte etc. USB keyboard data as one or multiple USB data packets to the host computer. When multiple USB data packets are needed to transmit each keyboard data packet (depending on the USB speed), they are transmitted in consecutive polling periods.

Abstract: Stilbene analogs and pharmaceutical compositions that are useful for the treatment of various cancers, including without limitation, colorectal cancer (CRC) and breast cancer are disclosed. The halogenated stilbene analogs include nitrogen heteroaryl groups and/or amino groups on the stilbene ring.

Abstract: A wind turbine generator system vibration detecting device and method are provided. The device comprises: a plurality of vibration sensors arranged on components of a wind turbine generator systems; at least one vibration switch arranged on a nacelle of the wind turbine generator system to detect a vibration signal of the nacelle and sends a fault signal to a control module if the detected vibration signal is larger than a turn-on threshold of the vibration switch; a vibration estimating module connected with the vibration sensors for processing vibration signals generated by the vibration sensors according to preset weighted values and a weighted formula in order to acquire a vibration state data, and comparing the vibration state data with a preset fault value and sending the fault signal to the control module if the vibration state data is not less than the fault value in accordance with the comparison.

Abstract: A method of synthesising a nano metric composite which has a core and shell structure includes preparing isometric metal oxide cores with an average diameter of less than 100 nm by a growth process via a liquid route. A double surfactant method is used which includes a first surfactant to obtain mono dispersal of the metal oxide cores and then a second surfactant to prepare the surface of the metal oxide cores, thereafter grafting a shell on each core.

Abstract: A hand operated puppet includes a pair of characters that are interconnected such that when the first character is in a display orientation the other character is in a storage orientation inside the first character. The head of one character is shaped and dimensioned to compressibly store the head of the other character. The head of each character includes an elastic, resilient foam insert shaped and dimensioned to conform to the contour of the face of the character.

Abstract: The invention relates to (among other things) oligomer-PTK inhibitor conjugates and related compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits advantages over PTK inhibitor compounds lacking a water soluble, non peptidic oligomer.

Abstract: According to one embodiment, there is provided an active material including a titanium oxide compound having a monoclinic titanium dioxide crystal structure and satisfying the equation (I). S1/(S2+S3)?1.9??(I). In the above equation, S1 is the peak area of a peak existing in a wavelength range from 1430 cm?1 to 1460 cm?1, S2 is the peak area of a peak existing in a wavelength range from 1470 cm?1 to 1500 cm?1, and S3 is the peak area of a peak existing in a wavelength range from 1520 cm?1 to 1560 cm?1, in the infrared diffusion reflective spectrum of the active material after pyridine is absorbed and then released.

Abstract: A refrigerator has a door, a lampshade and a lamp set, internal and external clamping walls and a seal retainer formed on the frame of the door. The lampshade and the lamp are set on the inner side of the frame of the door. The lamp is installed on the inner side of the doorframe, so that on the one hand the inner space of the refrigerator is not occupied by the illuminating device, and on the other hand, damage to the lamp caused by placing or taking goods relative to the refrigerator is prevented. Also, the lamp is installed on the door, and the light generated by the lamp irradiates inwardly to enhance the illuminating effect.

Abstract: According to one embodiment, there is provided an electrode material. The electrode material includes an active material which includes a titanium oxide compound having a monoclinic titanium dioxide crystal structure. The electrode material further includes a compound which exists on the surface of the active material and has a trialkylsilyl group represented by the formula (I). wherein R1, R2 and R3, which may be the same or different, respectively represent an alkyl group having 1 to 10 carbon atoms.

Abstract: The invention relates to (among other things) oligomer-PTK inhibitor conjugates and related compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits advantages over PTK inhibitor compounds lacking a water soluble, non peptidic oligomer.

Abstract: The invention relates to (among other things) oligomer-PTK inhibitor conjugates and related compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits advantages over PTK inhibitor compounds lacking a water-soluble, non-peptidic oligomer.

Abstract: The present invention fabricates mesocrystals of organic and organo-metallic compounds. Supersaturated solutions are made with different sums of an organic or organo-metallic compound and the organic or organo-metallic compound is added with an excipient. Through a water bath, mesocrystals are obtained from the supersaturated solutions with well-faceted nucleation and growth. Different polymorphisms are induced with different ratios of enantiomers. And the dissolution rate for fabricating the API is enhanced.

Abstract: The present invention belongs to the field of biological detection. Multi-line immunochromatographic test strip for semi-quantitative detection of aflatoxin B1 comprises a paperboard, wherein a water-absorbing pad, a detection pad, a gold-labeled pad and a sample pad are adhered sequentially on one surface of the paperboard from top to bottom, wherein each adjacent pads is overlapped and connected, the detection pad uses a nitrocellulose film as a backing pad, the nitrocellulose film is provided with a transverse control line, a test line I, a test line II and a test line III, wherein the control line is coated with a rabbit anti-mouse polyclonal antibody, and the test line I, test line II and test line III are coated with aflatoxin B1-bovine serum albumin conjugate (AFB1-BSA), respectively: and the gold-labeled pad is transversely coated with a nanogold-labeled anti-aflatoxin B1 monoclonal antibody.