Abstract: According to one embodiment, there is provided an active material for a battery. The active material includes secondary particle which contains primary particles of a monoclinic ?-type titanium composite oxide having an average primary particle diameter of 1 nm to 10 ?m. The secondary particle has an average secondary particle diameter of 1 ?m to 100 ?m. The secondary particle has compression fracture strength of 20 MPa or more.

Abstract: The invention provides protease inhibitors that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the protease inhibitors not attached to the water-soluble oligomer.

Abstract: Disclosed is a KVM extender system, which includes a first module, comprising a first processor, a first interface, a first Ethernet transceiver and includes a second module, comprising a second processor, a second interface, a second Ethernet transceiver. The KVM extender system transceives first data packet and second data packet transformed from first mass data of a first mass storage, second mass data of a second mass storage, keyboard/mouse data, audio/sound data with a cable therebetween. The first data packet and the second data packet transceived between the first and second Ethernet transceivers are controlled by a half duplex communication executed by two wires of the cable. Moreover, the first module further comprises a third interface to transceive third mass data from the computer coupled therewith. The third mass data is also transformed into third data packet to be transceived with the first and second data packets.

Abstract: A vacuum cleaner has a brush roll which has a housing. A motor is disposed within the housing and has a pulley mounted on a shaft of the motor. A roller is disposed within the housing and has a drive wheel. A belt couples the pulley to the drive wheel, so that the motor can drive the roller. The roller has bristles for sweeping a surface to be cleaned.

Abstract: Among other aspects, provided herein are multi-armed polymer conjugates comprising an alkanoate-linker, compositions comprising such conjugates, and related methods of making and administering the same. Methods of treatment employing such conjugates and related uses are also provided. The conjugates are prepared with high drug loading efficiencies.

Abstract: A transgenic animal model for evaluating growth, survival and/or metastasis of xenotransplanted normal or tumor cells or tissue is disclosed, in which a human growth factor, hHGF stimulates growth in vivo of human cells or tissue. A strain of Tg mice on the C3H background that is immunocompromised as a result of a homozygous scid gene has been bred which express a nucleic acid encoding hHGF/SE The ectopically expressed hHGF/SF ligand significantly enhances growth of human tumor cell lines and explanted tumor cells or tissue that express the Met receptor for hHGF. Such animals also have an enlarged normal livers and greater than normal liver regenerative capacity. Any Met-expressing hHGF-dependent human cells, including hepatocytes and various stem cells can survive and grow in such animals.

Abstract: The molecular mechanism underlying degenerative joint disease, also known as osteoarthritis (OA), is not fully understood. Disruption of mitogen inducible gene 6 (Mig-6) in mice by homologous recombination (KO mice) led to early onset OA as revealed by simultaneous enlargement and deformity of multiple joints, degradation of articular cartilage and the development of bony outgrowths or osteophytes within the joint space. The latter appeared to be derived from proliferation of mesenchymal progenitor cells followed by differentiation into chondrocytes. Because of the striking similarity to human OA, Mig-6 KO mice are a useful animal model for studying the mechanism of this disease and for testing new drugs or therapies for treating OA. These KO mice also developed epithelial hyperplasia, adenoma, and adenocarcinoma in organs such as lung, gallbladder, and bile duct. Mig-6 is therefore a tumor suppressor gene and is a candidate gene for the frequent Ip36 genetic alterations found in lung cancer.

Abstract: According to one embodiment, an active material for a battery includes a titanium composite oxide. The titanium composite oxide contains a monoclinic ?-type titanium composite oxide as its main phase and has a ratio (A2/A1) which is 0.4 or less, where A1 is an area intensity of a first peak existing in a frequency range of 105 cm?1 to 133 cm?1 and A2 is an area intensity of a second peak existing in a frequency range of 134 cm?1 to 154 cm?1 on a Raman spectrum measured using an argon laser having a wavelength of 514.5 nm.

Abstract: The invention relates to (among other things) oligomer-guanidine class conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over previously administered compounds.

Abstract: The invention relates to (among other things) oligomer-dantrolene conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over previously administered compounds.

Abstract: A USB converter circuit for converting electrical signals from a key scan circuit (in PS/2 or other formats) into USB signals for a computer while supporting N-key rollover (NKRO) functions. The converter circuit can be implemented as a stand-alone PS/2 to USB keyboard converter or as an integral component of a USB keyboard or KVM switch. The converter circuit includes a converter module that generates keyboard data packets in the USB format having a 16-byte, 64-byte, etc. format representing key press information for up to 8 modifier keys and 14, 62, etc. non-modifier keys, respectively. The converter circuit also includes a USB device controller module which transmits the 16-byte etc. USB keyboard data as one or multiple USB data packets to the host computer. When multiple USB data packets are needed to transmit each keyboard data packet (depending on the USB speed), they are transmitted in consecutive polling periods.

Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water soluble oligomer.

Abstract: A small size permanent magnet direct current motor has a housing accommodating a permanent magnet stator and a wound rotor. The rotor has a rotor core with a diameter of 23 mm±3 mm and 12 poles and a cylindrical commutator. The motor has an output power of more than 25 watts.

Abstract: The invention provides corticosteroids that are chemically modified by covalent attachment of a water soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits a reduced biological membrane crossing rate as compared to the biological membrane crossing rate of the corticosteroid not attached to the water soluble oligomer.

Abstract: A method for producing and distributing a child's toy encloses an expandable foam composition in a pliable fabric skin. The toy is compressed into a deflated configuration to form an inflatable toy and is shipped to a selected destination. The inflatable toy is delivered to a distributor and sold to an end user. The end user activates the foam to inflate the toy.

Abstract: A method for rapidly producing and distributing a new toy comprises the steps of designing a new dog toy by defining the shape and dimension of an inflated pliable exterior cover; and, producing, as soon as the dog toy is designed, and without requiring the design and construction of a mold, at least one thousand units of said new dog toy in a single day by utilizing an expandable foam composition in the cover.

Abstract: The present invention fabricates mesocrystals of organic and organo-metallic compounds. Supersaturated solutions are made with different sums of an organic or organo-metallic compound and the organic or organo-metallic compound is added with an excipient. Through a water bath, mesocrystals are obtained from the supersaturated solutions with well-faceted nucleation and growth. Different polymorphisms are induced with different ratios of enantiomers. And the dissolution rate for fabricating the API is enhanced.

Abstract: A cooling system for computer, a cooling apparatus and a cooling method are described. The cooling system includes a computer casing, a fan and the fan-less cooling apparatus. The fan-less cooling apparatus has an air passage with two open ends and a closed circumference. The air passage passes a heat dissipating part of the apparatus, one end of the air passage communicates with air outside the computer casing and the other end communicates with air inside the computer casing. a plurality of blowholes for the fan and the air passage are formed in the computer casing. There is at least one fan. Air is blown inside or outside through the blowholes, which causes a pressure difference between the interior and the exterior of the computer casing. The pressure difference leads an air flow to flow through the blowholes to dissipate heat.

Abstract: An exemplary light emitting diode (LED) light source includes a frame and light emitting units. The frame includes a supporting surface having a curved surface and one or more receiving holes configured in the curved surface. Each of the light emitting units is received in a respective receiving hole. Each of the light emitting units includes an LED die for generating light of two polarization states, a reflective polarizer for preferentially reflects one polarization state back into the LED die and preferentially transmitting the other polarization state out of the light emitting unit, a polarization converting film for converting the reflected light of the first polarization state into light of the second polarization state, and a reflective film for reflecting light of the converted second polarization state to the reflective polarizer.

Abstract: A die seal ring disposed outside of a die region of a semiconductor substrate is disclosed. The die seal ring includes a first isolation structure, a second isolation structure, and at least one third isolation structure disposed between the first isolation structure and the second isolation structure; a plurality of first regions between the first isolation structure, the second isolation structure and the third isolation structure; a second region under the first region and the third isolation structure; and a third region under the first isolation structure.