Patents by Inventor William A. Rowe

William A. Rowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160229806
    Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
    Type: Application
    Filed: September 14, 2015
    Publication date: August 11, 2016
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Patricia Hurter, William Rowe, Christopher R. Young, Adriana Costache, Patrick R. Connelly, Mariusz Krawiec, Yuchuan Gong, Yushi Feng, Martin Trudeau
  • Patent number: 9139530
    Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: September 22, 2015
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Patricia Hurter, William Rowe, Christopher R. Young, Adriana Costache, Patrick R. Connelly, Mariusz Krawiec, Yuchuan Gong, Yushi Feng, Martin Trudeau
  • Publication number: 20150118068
    Abstract: A fluid pump apparatus includes a pump chamber in a wellbore, a drive line capable of transferring a gas pressure to the pump chamber, a control system, an exhaust line, and a pressure sensor. The pressure sensor is capable of remotely sensing gas pressure in the exhaust line and providing communication to the control system. The control system is capable of determining when the fluid level in the pump chamber is full or near full based on input from the pressure sensor.
    Type: Application
    Filed: October 30, 2013
    Publication date: April 30, 2015
    Applicant: ENDOW ENERGY, LLC
    Inventors: Timothy Strunk, William A. Rowe
  • Publication number: 20140315948
    Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
    Type: Application
    Filed: June 27, 2014
    Publication date: October 23, 2014
    Inventors: William Rowe, Patricia Hurter, Christopher R. Young, Kirk Dinehart, Marinus Jacobus Verwijs, Kirk Overhoff, Peter D.J. Grootenhuis, Martyn Botfield, Alfredo Grossi, Gregor Zlokarnik, Fredrick F. Van Goor
  • Publication number: 20140272869
    Abstract: Disclosed are web-based CPR training and certification platforms comprising: 1) a controller device comprising: a first mode for collecting student compression data; a second mode for collecting student breath data; and a software module for transmitting the data to a server application; and 2) a server processor configured to provide an application comprising: a training mode, a practice mode, and a certification mode; a software module for providing a student interface; and a software module for providing an instructor interface. Optionally, feedback on student CPR psychomotor skills is provided in the form of a single-player or multi-player game played by performing the skills.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: Health & Safety Institute
    Inventors: John William HAMBELTON, William ROWE, Ralph M. SHENEFELT, William H. CLENDENEN, Adam KEISLING, Frank POWERS, JR.
  • Publication number: 20140242172
    Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
    Type: Application
    Filed: May 8, 2014
    Publication date: August 28, 2014
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Patricia Hurter, William Rowe, Christopher R. Young, Adriana Costache, Patrick R. Connelly, Mariusz Krawiec, Yuchuan Gong, Yushi Feng, Martin Trudeau
  • Patent number: 8754224
    Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: June 17, 2014
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Patricia Hurter, William Rowe, Christopher R. Young, Adriana Costache, Patrick R. Connelly, Mariusz Krawlec, Yuchuan Gong, Yushi Feng, Martin Trudeau
  • Patent number: 8711342
    Abstract: A joulemeter is capable of non-destructively measuring multiple characteristics of a laser beam. The joulemeter comprises a series of parallel probe beams, which are directed though a transparent media adjacent to an absorbing media that the tested beams pass through. Arrays of optical sensors or a chirp sensor are used to intercept and measure deflections the probe beams. A control unit renders measurements on selected properties of the laser.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: April 29, 2014
    Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
    Inventors: William Rowe Elliott, Randolph D. Glickman, Norman Barsalou, Saher M. Maswadi
  • Publication number: 20140112988
    Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
    Type: Application
    Filed: December 19, 2013
    Publication date: April 24, 2014
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: William Rowe, Patricia Hurter, Christopher Young, Kirk Dinehart, Marinus Jacobus Verwijs, Kirk Overhoff, Peter D.J. Grootenhuis, Martyn Botfield, Alfredo Grossi
  • Patent number: 8570159
    Abstract: Embodiments of the invention provide a method, system and computer program product for manifest integrity management via radio frequency identification (RFID). A manifest integrity management method can include scanning different RFID tags affixed to different objects for placement in a container. The method also can include determining both common data for all of the different RFID tags, and unique data for each of the different RFID tags. Finally, the method can include encoding an RFID tag for the container with an entry for the common data for the different RFID tags, and each unique data for each of the different RFID tags. In this way, a manifest can be created for the objects in the container.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: October 29, 2013
    Assignee: International Business Machines Corporation
    Inventors: Vijay Kumar Bhadriraju, Thomas Tim Hanis, Frederick William Rowe, John Kenneth Senegal, Donnie Allen Smith, Jr.
  • Patent number: 8410274
    Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: April 2, 2013
    Assignee: Vertex Pharmaceuticals
    Inventors: Patricia Hurter, William Rowe, Christopher Ryan Young, Adriana Costache, Patrick R. Connelly, Mariusz Krawiec, Yuchuan Gong, Yushi Feng, Martin Trudeau
  • Publication number: 20120258983
    Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
    Type: Application
    Filed: March 13, 2012
    Publication date: October 11, 2012
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: William Rowe, Patricia Hurter, Christopher R. Young, Kirk Dinehart, Marinus Jacobus Verwijs, Kirk Overhoff, Peter D.J. Grootenhuis, Martyn Botfield, Alfredo Grossi, Gregor Zlokarnik, Fredrick F. Van Goor
  • Publication number: 20120220625
    Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
    Type: Application
    Filed: February 10, 2012
    Publication date: August 30, 2012
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: William Rowe, Patricia Hurter, Christopher R. Young, Kirk Dinehart, Marinus Jacobus Verwijs, Kirk Overhoff, Peter D.J. Grootenhuis, Martyn Botfield, Alfredo Grossi, Gregor Zlokarnik, Fredrick F. Van Goor
  • Publication number: 20120214841
    Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
    Type: Application
    Filed: January 26, 2012
    Publication date: August 23, 2012
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Patricia Hurter, William Rowe, Christopher R. Young, Adriana Costache, Patrick R. Connelly, Mariusz Krawiec, Yuchuan Gong, Yushi Feng, Martin Trudeau
  • Publication number: 20120122922
    Abstract: Pharmaceutical compositions including N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and methods of using such compositions are described herein.
    Type: Application
    Filed: November 7, 2011
    Publication date: May 17, 2012
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Christopher R. Young, Charles William Rowe
  • Patent number: 8173120
    Abstract: The present invention relates to a method for substantially preventing a reduction in feed intake in an animal which occurs when said animal is administered an antibiotic, the method comprising administering to an animal in need of prevention of a reduction in feed intake, increasing doses of a composition comprising one or more antibiotics. The present invention also relates to a method for treating laminitis and fermentative acidosis in an animal in need of said treatment, the method comprising administering increasing doses of a composition comprising one or more antibiotics. The present invention further relates to a method for treating equine grass sickness and pulpy kidney in an animal in need of said treatment, the method comprising administering increasing doses of a composition comprising one or more antibiotics.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: May 8, 2012
    Assignee: Precision Nutrition Pty Ltd
    Inventors: James Baber Rowe, Christopher William Rowe
  • Publication number: 20120002193
    Abstract: A joulemeter is capable of non-destructively measuring multiple characteristics of a laser beam. The joulemeter comprises a series of parallel probe beams, which are directed though a transparent media adjacent to an absorbing media that the tested beams pass through. Arrays of optical sensors or a chirp sensor are used to intercept and measure deflections the probe beams. A control unit renders measurements on selected properties of the laser.
    Type: Application
    Filed: August 11, 2008
    Publication date: January 5, 2012
    Inventors: William Rowe Elliott, Randolph D. Glickman, Norman Barsalou, Saher M. Maswadi
  • Patent number: 8076357
    Abstract: Pharmaceutical compositions including N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and methods of using such compositions are described herein.
    Type: Grant
    Filed: May 26, 2009
    Date of Patent: December 13, 2011
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Christopher R. Young, Charles William Rowe
  • Patent number: 8052007
    Abstract: A container is disclosed including a plurality of seal blocks adapted to militate against the entry of a fluid into coolant channel headers formed in bipolar plates during a dip coating process, wherein the seal blocks are interconnected and include a fastening portion and a sealing portion, the sealing portion capable of being interchanged.
    Type: Grant
    Filed: January 10, 2008
    Date of Patent: November 8, 2011
    Assignee: GM Global Technology Operations LLC
    Inventors: Jeffrey M. Guzda, Mark W. Keyser, Timothy William Rowe, Steven J. Spencer
  • Patent number: 7931914
    Abstract: A uniaxially compressed dosage form manufactured by three-dimensional printing that preserves the predetermined internal architecture of the dosage form while producing an improved surface finish. The compression compacts the dosage form, eliminating at least some of the void space that remains at the end of conventional three-dimensional printing. Surface finish obtained as a result of the uniaxial compression process can be essentially equal to that obtained from conventional tablet pressing. Additionally, the internal structure or spatial variation of composition of the dosage form is preserved during the pressing operation, with geometric shrinkage occurring mostly in the direction of the axis of pressing. Further, as a result of compression, a greater quantity of API can be packed into a given final volume of dosage form.
    Type: Grant
    Filed: October 29, 2002
    Date of Patent: April 26, 2011
    Assignee: Massachusetts Institute of Technology
    Inventors: Wendy E. Pryce Lewis, Charles William Rowe, Michael J. Cima, Peter A. Materna