Abstract: A surgical stitching device is configured for single hand operation that enables passage of a suture needle through tissue with minimal operational requirement. The surgical needle is selectively securable to first and second jaws that are pivotably coupled to each other. When the first and second jaws are in an open configuration, in which, the first and second jaws are spaced apart, the suture needle is detachably secured to the first and second jaws. When the first and second jaws are in a closed configuration, in which, the first and second jaws are approximated, the suture needle is detachably secured to one of the first and second jaws and is detached from the other one of the first and second jaws. Such single hand operation facilitates procedures such as, e.g., extraterritorial loop suture closure.

Abstract: A system and method for removing a wrinkle adjacent to a joint between a first surface material and a second surface material, different from the first surface material. The system and method may include directing a flow of air creating an air wall across the first surface material adjacent to the joint where the wrinkle is being removed from the second surface material; directing heat onto the wrinkle in the second surface material; and working out the wrinkle from the second surface material while the second surface material is at an elevated temperature.

Abstract: Embodiments of substrate supports for use in substrate processing chambers are provided herein. In some embodiments, a substrate support includes: an upper assembly having a base plate assembly coupled to a lower surface of a cooling plate, wherein the base plate assembly includes a plurality of electrical feedthroughs, and wherein the cooling plate includes a plurality of openings aligned with the plurality of electrical feedthroughs; an electrostatic chuck disposed on the upper assembly and removably coupled to the cooling plate, wherein the electrostatic chuck has a chucking electrode disposed therein that is electrically coupled to a first pair of electrical feedthroughs of the plurality of electrical feedthroughs; and an inner tube coupled to the cooling plate and configured to provide an RF delivery path to the electrostatic chuck.

Abstract: There is presented a system and method for detecting mobile device fault conditions, particularly detecting defects in a display or housing of a mobile device. One or more cameras included within the mobile device are used with a reflecting surface in a test fixture to obtain properly aligned and formatted images of the external housing and display of the mobile device, and interactive guidance assists with placement and execution of diagnostics. A remote server conducts further analysis of the captured images, and then defect status may be returned to and displayed upon the mobile device screen.

Abstract: In general, the invention relate to providing computer implemented services using information handling systems. One or more embodiments includes after being allocated to a composed information handling system of the composed information handling systems: monitoring health of a hardware resource of the composed information handling system, making a determination, based on the monitoring of the health of the hardware resource, that the hardware resource is in a compromised state, and based on the determination, initiating a hardware replacement operation using replacement option information (ROI) for the hardware resource and replacement conditions for the hardware resource.

Abstract: An exemplary self-locking actuator mechanism includes a floating plate and a linear actuator. The floating plate defines a first slot that includes a first central portion, a first jog extending laterally from a first end of the first central portion, and a second jog extending laterally from a second end of the first central portion. The linear actuator includes a shaft pivotably connected to the floating plate, and is operable to drive the shaft between a first shaft position and a second shaft position to thereby move the self-locking actuator mechanism between a first locking state and a second locking state.

Abstract: The present disclosure relates to improved methods of treatment with nirogacestat.

Abstract: A method for detecting and/or localizing keyboard accessibility failures (KAFs) in a web page is disclosed. A document object model of a web page is read. A keyboard navigation flow model is generated from the document object model of the web page based on interactions of a user with the web page. The model includes states representing user interfaces displayed by the web page, nodes representing keyboard inputs in the states, and edges representing transitions that occur in the web page between the nodes. KAFs are detected based on an analysis of the keyboard navigation flow model. A report of the detected one or more KAFs on the web page is produced. The KAFs include unintuitive navigation failures, reflow related failures, and dialog related failures.

Abstract: A field adjustable output control usable with a luminaire to adjust dimming employs a first resistance source, and at least a second resistance source, and a shunt voltage regulator having a reference node coupled between the first and the second resistance sources to form a voltage divider that provides a reference voltage to the shunt voltage regulator, wherein the shunt voltage regulator is electrically coupled between an LED driver dimming line and a ground via first and second nodes of the shunt voltage regulator to regulate a flow of current from the LED driver dimming line based on the reference voltage supplied via the voltage divider. The second resistance source can take the form of a plurality of discrete resistors, each having a respective value of resistance, or alternatively can take the form of a potentiometer having a continuously variable value of resistance associated therewith.

Abstract: Embodiments of a target support plate and a method for manufacturing targets used for low melting point materials, typically Gallium and Rubidium, with commercial cyclotrons including various embodiments of the targets are described. The target for low melting point materials includes a target support plate having a front face and a back face, the front face having formed therein a plurality of slots to contain a target material: the plurality of slots is arranged to be in a horizontal position, with a grazing angle of 5° to 15°, with respect to the irradiation proton beam for initiating a nuclear reaction; and may include a plurality of cooling channels formed on the back face of the target support plate to cool the target support plate during formation of a radioisotope from the formed low melting point material by a flow of a cooling fluid therein during irradiation of the target.

Abstract: This disclosure provides methods for preparing a sequencing library including the steps of providing a template nucleic acid sequence, dNTPs, dUTP, a primer, a polymerase, a dUTP excising enzyme, and a plurality of beads including oligonucleotide adapter sequence segments; amplifying the template nucleic acid with the polymerase, dNTPs, dUTP and random hexamer to provide a complementary nucleic acid sequence including occasional dUTPs; and excising the incorporated dUTPs with the dUTP excising enzyme to provide nicks in the complementary nucleic acid sequence to provide a sequencing library.

Abstract: Systems and methods are presented herein for providing an integrated disconnect. The integrated disconnect may be used within a drive unit. The integrated disconnect comprises an output gear having a cavity. A torque transfer adapter is arranged within the cavity. A clutch body is also arranged within the cavity. The clutch is actuatable through the output gear by an actuator to engage and disengage the clutch with the torque transfer adaptor. The actuator is located external to the cavity.

Abstract: A sulfonated water-dispersible thermoplastic copolymer material for use as a support material in an additive manufacturing process is made by a method comprising providing a selected thermoplastic copolymer having an acid or an anhydride group; esterifying the acid group of the selected thermoplastic copolymer with a hydroxyl-functionalized sulfonate salt, or amidizing the acid group of the selected thermoplastic copolymer with an amine sulfonate salt, or imidizing the anhydride group of the selected thermoplastic copolymer with an amine sulfonate salt. The esterification, the amidization or the imidization results in a sulfonated water thermoplastic dispersible copolymer having a glass transition temperature suitable to provide an effective support during the additive manufacturing process and wherein the sulfonated water-dispersible thermoplastic copolymer will disperse in tap water in less than 1 hour.

Abstract: Provided is a system and method for determining an appropriate dosage of a product. The method includes, receiving from a User a User Request for a Dosage, the User Request including at least a User Reason and a User Location; accessing a Database of Products, each Product having at least one Constituent, at least one Established Reason, a Dosage for each Established Reason, and Provider Location; querying the Database of Products with the User Request to determine at least a first subset of Products having the at least one Established Reason correlating to the User Reason; and providing the User with the first subset of Products arranged by proximity of the Provider Location to the User Location, the first subset of Products further including the Dosage for each Product in the first subset of Products. An associated system is also provided.

Abstract: Methods and OLED devices are provided in which organic emissive materials are deposited over a substrate via OVJP print heads in a continuous line extending from one edge of the active display portion of a substrate to another. The print heads are arranged such that the sidewalls of the OVJP jet are disposed over non-emissive insulating portions of the display panel, thereby allowing for improved pixel density and resolution in comparison to conventional OVJP and similar techniques.

Abstract: A method of distributing media content using mobile communication devices including providing media access cards which promote selected media content to users of such devices whereby a user may access a web server associated with the media access cards and download application software enabling access to selected media content via a mobile device, the media access cards including a machine readable identification number code that identifies media content associated with the card whereby the application software facilitates reading and transmitting the code to a web server via the mobile device, receiving the identification number with the web server and using the identification number to locate a table value in a database wherein a plurality of media access cards identification numbers are associated with a media content table value, using the table value to identify media codes associated with the selected content server which transmits media to the mobile device.

Abstract: The present application discloses novel compounds of formula (I), pharmaceutical compositions containing these compounds and methods of inducing degradation of a protein, comprising contacting the protein with an effective amount of a compound of the disclosure. Methods of treating disease and disorders that results from abnormal activity of a target protein in a subject, are also disclosed.

Abstract: A storage container with various aspects is described herein. The storage container may have cleats or cleat receptacles to interact with other storage containers and/or accessories. The storage container may also include rails for attachment of various accessories. Some versions of the storage container may further include telescopic uprights connected to a handle. Many of the versions of the storage containers may further include wheels for transporting the storage containers and their contents.

Abstract: An automatic feed system for a trimmer is provided. Such trimmers include a line that can be spun at high speeds to cut vegetation along roadsides or other areas. The automatic feed system is configured to dynamically detect the current length of the line and automatically feed the line to maintain a maximum or desired length for cutting. This length may typically correspond with the radius of a trimmer deck in which the line spins.

Abstract: An ophthalmically compatible solution includes (a) about 0.005 to about 2 wt. %, based on the total weight of the ophthalmically compatible solution, of hyaluronic acid or a salt thereof; (b) about 0.01 to about 1 wt. %, based on the total weight of the ophthalmically compatible solution, of erythritol; (c) sodium chloride, potassium chloride or any combination thereof; and (d) one or more buffers.