Abstract: Orthopedic device for treating neuropathic ulcers and other injuries while allowing easy access to the wound site on the plantar surface of a patient's foot includes a base portion and a sole that is either movably connected or removably connected to either the base or to a strut member. The base or strut is maintained in position on the lower leg while the sole may be rotated, slid, or completely removed for allowing inspection and access to the plantar surface of the patient's foot.

Abstract: An orthopedic device includes a strut assembly having a resilient shell defining opposed first and second sides, and a patient compliance system. The patient compliance includes a tightening strap connecting the first and second sides of the shell. The tightening strap has first and second end portions arranged for incremental uni-directional adjustment relative to at least one of the first and second sides of the strut assembly. The tightening strap is arranged to bend the shell and draw the first and second sides thereof toward one another.

Abstract: Orthopedic device for treating neuropathic ulcers and other injuries while allowing easy access to the wound site on the plantar surface of a patient's foot includes a base portion and a sole that is either movably connected or removably connected to either the base or to a strut member. The base or strut is maintained in position on the lower leg while the sole may be rotated, slid, or completely removed for allowing inspection and access to the plantar surface of the patient's foot.

Abstract: An orthopedic device as in a dorsal splint for treating plantar fasciitis includes a substantially rigid splint member having an overmolded flexible edge and living hinges, or substantially rigid component pieces received in a flexible member, to provide improved and more comfortable fitting to a user and reduced storage requirements. The splint member is shaped and configured to engage the dorsal aspects of a user's lower leg, ankle, and foot. A soft-good strap system is provided to maintain the dorsal splint in position and has suitable padding to treat various foot conditions.

Abstract: A tubular element including a wall defining therein an inner cavity, and a plurality of microchannels supported by the wall and extending along a length of the wall.

Abstract: An orthopedic device as in a dorsal splint for treating plantar fasciitis includes a substantially rigid splint member having an overmolded flexible edge and living hinges, or substantially rigid component pieces received in a flexible member, to provide improved and more comfortable fitting to a user and reduced storage requirements. The substantially rigid splint member is shaped and configured to the dorsal aspects of a user's lower leg, ankle, and foot. Straps are provided to maintain the dorsal splint in position.

Abstract: Disclosed is an optimized process and apparatus for more efficiently and economically carrying out the liquid-phase oxidation of an oxidizable compound. Such liquid-phase oxidation is carried out in a bubble column reactor that provides for a highly efficient reaction at relatively low temperatures. When the oxidized compound is para-xylene and the product from the oxidation reaction is crude terephthalic acid (CTA), such CTA product can be purified and separated by more economical techniques than could be employed if the CTA were formed by a conventional high-temperature oxidation process.

Abstract: An orthopedic device includes a strut assembly having a resilient shell defining opposed first and second sides, and a patient compliance system. The patient compliance includes a tightening strap connecting the first and second sides of the shell. The tightening strap has first and second end portions arranged for incremental uni-directional adjustment relative to at least one of the first and second sides of the strut assembly. The tightening strap is arranged to bend the shell and draw the first and second sides thereof toward one another.

Abstract: An orthopedic device as in a dorsal splint for treating plantar fasciitis includes a substantially rigid splint member having an overmolded flexible edge and living hinges, or substantially rigid component pieces received in a flexible member, to provide improved and more comfortable fitting to a user and reduced storage requirements. The substantially rigid splint member is shaped and configured to engage the dorsal aspects of a user's lower leg, ankle, and foot. Straps are provided to maintain the dorsal splint in position.

Abstract: An orthopedic device as in a dorsal splint for treating plantar fasciitis includes a substantially rigid splint member having an overmolded flexible edge and living hinges, or substantially rigid component pieces received in a flexible member, to provide improved and more comfortable fitting to a user and reduced storage requirements. The splint member is shaped and configured to engage the dorsal aspects of a user's lower leg, ankle, and foot. A soft-good strap system is provided to maintain the dorsal splint in position and has suitable padding to treat various foot conditions.

Abstract: Orthopedic device for treating neuropathic ulcers and other injuries while allowing easy access to the wound site on the plantar surface of a patient's foot includes a base portion and a sole that is either movably connected or removably connected to either the base or to a strut member. The base or strut is maintained in position on the lower leg while the sole may be rotated, slid, or completely removed for allowing inspection and access to the plantar surface of the patient's foot.

Abstract: A child resistant product dispenser includes a blister card having compartments for holding a product a housing, and a blister cover for use in covering the blister card compartments. The blister cover may include a dispensing area for each compartment of the blister card. To remove a product from the product dispenser the user presses a dispensing area against either a compartment thereby forcing the product through a frangible area on the blister card and through a frangible area in the housing or against a peelable area on the blister card and a frangible area in the housing. This creates an opening through which the product is removed.

Abstract: A child resistant product dispenser includes a blister card having compartments for holding a product, a housing, and a blister cover for use in covering the blister card compartments. The blister cover may include a dispensing area for each compartment of the blister card. To remove a product from the product dispenser the user presses a dispensing area against either a compartment thereby forcing the product through a frangible area on the blister card and through a frangible area in the housing or against a peelable area on the blister card and a frangible area in the housing. This creates an opening through which the product is removed.

Abstract: A multi-layer medication carrier or blister card may comprise a plurality of layers. A support layer is provided with one or more openings to receive corresponding blisters formed in a blister layer. A backing layer is provided over the blister layer to form one or more enclosures capable of holding unit doses of a medication. Perforations provided in at least the blister layer define unit dose packages. Dimples may be provided in the blister layer within a boundary defined by the perforations, which dimples may be used to ensure subsequent ejection of each unit dose package. An adhesive-free region in the backing layer may be provided in alignment with the perforations defining each unit dose package to further ensure proper ejection. Additionally, a partial-depth cut in the backing layer may be provided in substantial alignment with each blister, thereby facilitating removal of the unit dose of medication.

Abstract: The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.

Abstract: A child-resistant package for pharmaceutical articles includes a blister pack having a product casing layer defining blisters, a foil closure layer enclosing articles in the blisters and a reinforcing layer preventing dispensing of each article until an access mechanism is used. Each access mechanism includes a puncturing element of the product casing layer and a tear-away element of the reinforcing layer defined by a perforation line. The puncturing element includes a pointed portion for separating a first end of the tear-away element. Application of pulling force to the first end further separates the tear-away element to expose the foil layer adjacent the blister for dispensing the article. According to one embodiment, the package includes an outer jacket having a mounting portion receiving the blister pack and a cover movable with respect to the mounting portion between opened and closed positions.

Abstract: One embodiment of the present method and apparatus for multi-protocol digital communications conducts a first portion of a communication between a first information processing device and a second information processing device in accordance with a first communication protocol. A second portion of the communication is conducted in accordance with at least a second communication protocol, where the second communication protocol is different from the first communication protocol. The communication may be divided into further portions, where each portion of the communication is conducted in accordance with a different communication protocol.

Abstract: A valve assembly including valve portion including a bore, a spool received within the bore and configured for axial movement along the longitudinal axis between an open position in which fluid flow through the bore is permitted and a closed position in which fluid flow through the bore is prevented. An impellor is coupled to the spool and configured to rotate the spool about the longitudinal axis.

Abstract: A density evaluator for a metal-inclusive component includes a simulator and a meter. The simulator includes a receiving portion for receiving at least a portion of a metal-inclusive component. The meter is operatively connected with the simulator. The meter obtains an inductance value associated with the metal-inclusive component and the inductance value is used to determine a density value. A method and system for evaluating a density of a metal-inclusive component is also disclosed.

Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.