Patents by Inventor William Duncan

William Duncan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9090562
    Abstract: The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: July 28, 2015
    Assignee: Epizyme, Inc.
    Inventors: Kevin Wayne Kuntz, Richard Chesworth, Kenneth William Duncan, Heike Keilhack, Natalie Warholic, Christine Klaus, Sarah Kathleen Knutson, Timothy James Nelson Wigle, Masashi Seki, Syuji Shirotori, Satoshi Kawano
  • Publication number: 20150065483
    Abstract: The present invention relates to substituted 6,5-fused bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Application
    Filed: November 7, 2014
    Publication date: March 5, 2015
    Inventors: Kevin Wayne Kuntz, Edward James Olhava, Richard Chesworth, Kenneth William Duncan
  • Patent number: 8962620
    Abstract: The present invention relates to substituted 6,5-fused bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Grant
    Filed: November 4, 2013
    Date of Patent: February 24, 2015
    Assignee: Epizyme, Inc.
    Inventors: Kevin Wayne Kuntz, Edward James Olhava, Richard Chesworth, Kenneth William Duncan
  • Publication number: 20140288041
    Abstract: The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: May 12, 2014
    Publication date: September 25, 2014
    Applicant: EPIZYME, INC.
    Inventors: Kevin Wayne Kuntz, Richard Chesworth, Kenneth William Duncan, Heike Keilhack, Natalie Warholic, Christine Klaus, Sarah Kathleen Knutson, Timothy James Nelson Wigle, Masashi Seki, Syuji Shirotori, Satoshi Kawano
  • Patent number: 8765732
    Abstract: The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: July 1, 2014
    Assignee: Epizyme, Inc.
    Inventors: Kevin Wayne Kuntz, Richard Chesworth, Kenneth William Duncan, Heike Keilhack, Natalie Warholic, Christine Klaus, Sarah Kathleen Knutson, Timothy James Nelson Wigle, Masashi Seki, Syuji Shirotori, Satoshi Kawano
  • Publication number: 20140142083
    Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: April 13, 2012
    Publication date: May 22, 2014
    Applicant: EPIZYME, INC.
    Inventors: Kevin Wayne Kuntz, Richard Chesworth, Kenneth William Duncan, Heike Keilhack, Natalie Warholic, Christine Klaus, Sarah K. Knutson, Timothy James Nelson Wigle, Masashi Seki
  • Publication number: 20140057891
    Abstract: The present invention relates to substituted 6,5-fused bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Application
    Filed: November 4, 2013
    Publication date: February 27, 2014
    Applicant: Epizyme, Inc.
    Inventors: Kevin Wayne Kuntz, Edward James Olhava, Richard Chesworth, Kenneth William Duncan
  • Patent number: 8598167
    Abstract: The present invention relates to substituted 6,5-fused bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: December 3, 2013
    Assignee: Epizyme, Inc.
    Inventors: Kevin Wayne Kuntz, Edward James Olhava, Richard Chesworth, Kenneth William Duncan
  • Publication number: 20130317026
    Abstract: The present invention relates to substituted 6,5-fused bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Application
    Filed: July 9, 2013
    Publication date: November 28, 2013
    Applicant: EPIZYME, INC.
    Inventors: Kevin Wayne Kuntz, Edward James Olhava, Richard Chesworth, Kenneth William Duncan
  • Publication number: 20130103695
    Abstract: Various technologies described herein pertain to detecting machine translated content. Documents in a document pair are mutual lingual translations of each other. Further, document level features of the documents in the document pair can be identified. The document level features can correlate with translation quality between the documents in the document pair. Moreover, statistical classification can be used to detect whether the document pair is generated through machine translation based at least in part upon the document level features. Further, a first document can be a machine translation of a second document in the document pair or a disparate document when generated through machine translation.
    Type: Application
    Filed: October 21, 2011
    Publication date: April 25, 2013
    Applicant: Microsoft Corporation
    Inventors: Spencer Taylor Rarrick, William Duncan Lewis, Christopher Brian Quirk, Anthony Aue
  • Publication number: 20130018650
    Abstract: An intelligent selection system selects language model training data to obtain in-domain training datasets. The selection is accomplished by estimating a cross-entropy difference for each candidate text segment from a generic language dataset. The cross-entropy difference is a difference between the cross-entropy of the text segment according to the in-domain language model and the cross-entropy of the text segment according to a language model trained on a random sample of the data source from which the text segment is drawn. If the difference satisfies a threshold condition, the text segment is added as an in-domain text segment to a training dataset.
    Type: Application
    Filed: February 1, 2012
    Publication date: January 17, 2013
    Applicant: MICROSOFT CORPORATION
    Inventors: Robert Carter Moore, William Duncan Lewis
  • Publication number: 20120298103
    Abstract: A compact respiratory protective device fitted with a mouthpiece or mouthpiece assembly that retracts, pivots or rotates into the depth of the device to reduce size when packed. This reduction in size also permits the depth of the downstream air channel to be increased while still producing a compact device. This increase in the depth of the downstream air channel maximizes the efficiency and capacity of the filter assembly and reduces the inhalation resistance of the device. The reduced breathing resistance enhances usability.
    Type: Application
    Filed: January 24, 2011
    Publication date: November 29, 2012
    Inventors: William Duncan Wood, Robin Middlemass Howie
  • Publication number: 20120238451
    Abstract: The invention provides methods and herbicide compositions for weed control. The invention provides for enhancement of herbicide activity by the addition of an adjuvant. The herbicide activity is especially useful as a preplant and postplant treatment.
    Type: Application
    Filed: March 16, 2012
    Publication date: September 20, 2012
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: Paul Feng, Ronald Brinker, William Duncan, Alejandro Perez-Jones
  • Patent number: 8119178
    Abstract: This invention is a novel composition for preserving fresh cut apples comprising a mixture of ascorbic acid, and one or more of calcium chloride, calcium carbonate, magnesium chloride, calcium hydroxide, and optionally, citric acid or sodium citrate. This invention also relates to a method of preserving fresh cut apples by treating the cut apples with the novel composition dissolved in water and packaging the treated fresh cut apples in a modified atmosphere package.
    Type: Grant
    Filed: January 18, 2011
    Date of Patent: February 21, 2012
    Assignee: Natureseal, Inc.
    Inventors: Perry D. Lidster, William Duncan, Miriam O'Donovan, Cheong Kit Leung
  • Publication number: 20110111103
    Abstract: This invention is a novel composition for preserving fresh cut apples comprising a mixture of ascorbic acid, and one or more of calcium chloride, calcium carbonate, magnesium chloride, calcium hydroxide, and optionally, citric acid or sodium citrate. This invention also relates to a method of preserving fresh cut apples by treating the cut apples with the novel composition dissolved in water and packaging the treated fresh cut apples in a modified atmosphere package.
    Type: Application
    Filed: January 18, 2011
    Publication date: May 12, 2011
    Applicant: NATURESEAL, INC.
    Inventors: Perry D. Lidster, William Duncan Powrie, Miriam O'Donovan, Cheong Kit Leung
  • Patent number: 7931926
    Abstract: This invention is a novel composition for preserving fresh cut apples comprising a mixture of ascorbic acid, and one or more of calcium chloride, calcium carbonate, magnesium chloride, calcium hydroxide, and optionally, citric acid or sodium citrate. This invention also relates to a method of preserving fresh cut apples by treating the cut apples with the novel composition dissolved in water and packaging the treated fresh cut apples in a modified atmosphere package.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: April 26, 2011
    Assignee: NatureSeal, Inc.
    Inventors: Perry D. Lidster, William Duncan Powrie, Miriam O'Donovan, Cheong Kit Leung
  • Publication number: 20070136166
    Abstract: Methods and systems consistent with the present invention overcome the shortcomings of existing trading systems by providing an invoiceless trading system that creates incentives for customers to pay suppliers within a predetermined period of time, such as a settlement period. Specifically, the invoiceless trading system enables a customer to obtain a discount on orders placed with suppliers in return for an immediate payment (e.g., within 24 hours) by the customer. The supplier receives payment within the predetermined period of time, and the customer receives additional cash benefits by providing an early payment to the supplier. To communicate with and transfer funds between customers and suppliers, the invoiceless trading system may use an electronic gateway and a settlement bank. In addition to creating an incentive to embrace e-commerce, both customers and suppliers avoid the need to manually process orders and use invoices to complete transactions.
    Type: Application
    Filed: January 16, 2007
    Publication date: June 14, 2007
    Inventor: William Duncan
  • Publication number: 20070094570
    Abstract: Provided are a method, system, and an article of manufacture for detecting errors while accessing a storage device. A host system writes an identical initialization pattern into each block of a plurality of blocks while formatting the storage device. Each block of the plurality of blocks has a checksum field capable of containing a value. Any host system generates an error when data from a retrieved block from the plurality of blocks computes to a checksum that is different from the value contained within the checksum field for the retrieved block, and the retrieved block does not contain the initialization pattern.
    Type: Application
    Filed: October 3, 2006
    Publication date: April 26, 2007
    Applicant: Sun Microsystems, Inc.
    Inventors: William Duncan, Wayne Ihde, Michael Tibbetts
  • Publication number: 20070063107
    Abstract: A reusable module is affixed atop a reusable orbital vehicle (OV). Various configurations of the reusable module have identical external dimensions in the region of attachment to the OV to permit interchangeability. Different configurations can accommodate a variety of missions of different type and duration. A variety of cargo modules of different configurations allow cargo to be uplifted into orbit. In one embodiment, the cargo module is an unpressurized cargo module in which the cargo is exposed to the environment of space during the unloading process. The cargo module may also be a pressurized cargo module. In an alternative embodiment, the cargo module may include both a pressurized cargo module and unpressurized cargo module.
    Type: Application
    Filed: May 10, 2006
    Publication date: March 22, 2007
    Applicant: Kistler Aerospace Corporation
    Inventors: George Mueller, Richard Kohrs, William Duncan, David Cochran, Dean Misterek, Terrill Burlison, Ryan Curtis, Thomas Johnson, Richard Bailey, Charles Limerick
  • Patent number: D525659
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: July 25, 2006
    Assignee: Coin Acceptors, Inc.
    Inventors: Thomas S. Paczkowski, David William Duncan, Roger O. Claghorn, Tate L. Neilson, Michael J. Justin, Gary M. Ochterbeck, Travis William Mills