Abstract: A method of frequency discrimination associated with the Doppler effect is presented. The method includes mapping a first signal to a first plurality of frequency bins and a second signal to a second plurality of frequency bins. The first signal and the second signal corresponding to different times. The method also includes firing a first plurality of neurons based on contents of the first plurality of frequency bins and firing a second plurality of neurons based on contents of the second plurality of frequency bins.

Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods compositions, and kits generated through rational design of siRNAs are disclosed, including those directed to the nucleotide sequences for HAO1.

Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for TTR.

Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods compositions, and kits generated through rational design of siRNAs are disclosed, including those directed to the nucleotide sequences for AAT.

Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods compositions, and kits generated through rational design of siRNAs are disclosed, including those directed to the nucleotide sequences for F12.

Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for TTR.

Abstract: A pump body is pre-compressed by expanding a displacement plug in a cavity to pre-compress a portion of a pump body comprising a piston bore, an inlet bore and an outlet bore spaced from said cavity, and connected in a pump assembly. A fluid pump assembly is made up of a plurality of pump bodies connected side by side between opposing end plates with a plurality of fasteners tightened to compress the pump bodies between the end plates, wherein each pump body comprises a piston bore, an inlet bore, an outlet bore and an expanded displacement plug in a cavity; and wherein the expanded displacement plug applies a pre-compressive force at the cavity on each of the pump bodies.

Abstract: A method of frequency discrimination associated with the Doppler effect is presented. The method includes mapping a first signal to a first plurality of frequency bins and a second signal to a second plurality of frequency bins. The first signal and the second signal corresponding to different times. The method also includes firing a first plurality of neurons based on contents of the first plurality of frequency bins and firing a second plurality of neurons based on contents of the second plurality of frequency bins.

Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for CTNNB1.

Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed.

Abstract: A system for powering wellsite surface equipment comprises at least one prime mover in communication with a fuel source for powering the prime mover and having at least one heat source, at least one pump arranged to be driven by the prime mover, the at least one pump in fluid communication with at least one wellbore and at least one fluid for use in the wellbore, and at least one auxiliary system in communication with the heat source from the at least one prime mover.

Abstract: A global composition system is described. In one or more implementations, the global composition system may be configured to perform rendering for a plurality of applications. For example, the global composition system may be configured to expose one or more application programming interfaces (APIs) that are accessible to the applications. The APIs may then be used to cause a single composition engine to perform the rendering for the plurality of applications. The use of a single composition engine may be used to support a variety of different functionality, such as to perform efficient rendering by knowing what elements are provided by each of the applications and how those items relate for rendering to a display device.

Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for MYD88.

Abstract: An apparatus and method for converting an object from viewpoint-relative coordinates to object-relative coordinates are provided. The method includes obtaining an object identifier from an object record of the object, obtaining a minimum x-coordinate and a maximum x-coordinate of the object from the object record, obtaining a minimum y-coordinate and a maximum y-coordinate of the object from the object record, obtaining the x-coordinates and the y-coordinates of the object to be transformed from the viewpoint-relative coordinates to the object-relative coordinates, storing the object identifier of the object to a first channel of an auxiliary buffer, transforming the x-coordinates of the object and storing the transformed x-coordinates to a second channel of the auxiliary buffer, and transforming the y-coordinates of the object and storing the transformed y-coordinates to a third channel of the auxiliary buffer.

Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for CTNNB1.

Abstract: A system for powering wellsite surface equipment comprises at least one prime mover in communication with a fuel source for powering the prime mover and having at least one heat source, at least one pump arranged to be driven by the prime mover, the at least one pump in fluid communication with at least one wellbore and at least one fluid for use in the wellbore, and at least one auxiliary system in communication with the heat source from the at least one prime mover.

Abstract: A process of cleansing by applying continuous multiple-ply sections of material comprised of dry sections of material alternating with potentially wet sections of material in which liquid is encased and becomes permeable with application of pressure. The sections can be manufactured into a roll separated by perforation. The sections can also be manufactured into flat sections separated by perforation or laid flat independently or folded one on top of the other. The sections can be configured in an unlimited combination of dry and potentially wet sections, composition of dry materials, composition of liquids, dimensions, connectivity, sizes, thickness and properties that synergistically improve the cleansing process when used in combination together. Habitual waste of materials can be progressively reduced, and ply materials are biodegradable and 100% recyclable providing for environmental preservation.

Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for TTR.

Abstract: A device and related methodologies to deliver molecules to the cells that comprise any tissues. The invention includes a catheter-based electrode and methods for its use for the delivery of molecules to cardiac tissue, blood vessels, other tissues/organs that can be accessed through a luminal tissue, and luminal tissues. The invention is also a non-catheter based electrode for performing the same functions. In certain embodiments the electrode utilizes a segmented electrode array wherein each electrode is separately addressable by a source of electricity.

Abstract: Methods and systems provide a financial account. In one implementation, one or more funding payments for a financial account are received from an investor. The financial account includes a mutual fund. The investor takes withdrawals from the financial account. A balance of the financial account is calculated by a processor. Benefit payments are paid to the investor after the balance of the financial account has reached zero.