Abstract: A resealable bag having an integrated manual pump is provided. The resealable bag includes: a front wall and a back wall together defining a cavity, a sealable closure configured to seal an opening to the cavity, and a manual pump positioned within an aperture in the front wall, wherein the manual pump includes a frame around a perimeter of the aperture, a pump ball positioned within the frame, and an ingress valve and an egress valve in fluid communication with an interior of the pump ball. Air is removed from the bag by depressing the pump ball, which forces air through the egress valve from the interior of the pump ball to an exterior of the bag. The pump ball refills with air between depressions due to air from the bag cavity entering the pump ball through the ingress valve disposed on a cavity-facing surface of the pump ball.

Abstract: Provided are compounds of Formula (I); and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.

Abstract: In some implementations, a receiver may obtain a digitized output of a radio frequency (RF) analog-to-digital-converter (ADC) of the receiver. The receiver may apply a spur cancellation to the digitized output of the RF ADC to attenuate one or more continuous wave spurs from the digitized output of the RF ADC, wherein the spur cancellation is based on a frequency planning with coherent averaging.

Abstract: Mobile training labs for training gas technicians are disclosed. The mobile training labs can include a towable trailer comprising a body having a plurality of walls at least partially defining a hollow interior, an axle having at least two wheels disposed thereon to support the body, and a tow hitch. The mobile training labs can also include at least one training bay connected to the towable trailer such that the at least one training bay is configured to be accessed from an exterior of the towable trailer. The at least one training bay can include a work bench and a mock service entrance that is representative of a commercial or residential gas service entrance.

Abstract: Provided are multispecific antibodies or antigen binding fragments thereof comprising at least one first antigen-binding region capable of binding specifically to pyroglutamate amyloid-? and a second antigen-binding region capable of binding specifically to transferrin receptor (TfR). Also provided are methods of treating or detecting a neurological disorder and/or delivering a therapeutic or diagnostic agent across the blood-brain barrier. Also described are nucleic acids encoding the antibodies, vectors comprising the nucleic acids, recombinant host cells comprising the nucleic acids and/or vectors, and methods of producing the multispecific antibodies or antigen binding fragments thereof.

Abstract: A computing platform may train a machine learning model to detect and analyze threat actor activities. The computing platform may generate dynamic honeypotted files and deploy the generated dynamic honeypotted files as adaptive defenses to threat actors in a computing environment. The computing platform may adapt to threat actor activities based on analyzed behavior of the threat actor and any identified tools used by the threat actor to gain access to the computing system. Threat actor activities may be written to a blockchain to publicly record all transactions related to a threat actor's activities for analysis and generation of adaptive defenses to threat actor attacks. The computing platform may cause redirection of the threat actor into a specific computing environment through generation and deployment of dynamic honeypotted files.

Abstract: An incident management system for managing an incident response may be provided. The incident management system may include an incident management (IM) computing device and a vehicle. The IM computing device may include a processor and memory, the processor may be programmed to receive a notification that an incident has occurred, the notification including sensor data and sub-system data. The processor may analyze the data to determine an incident response, the determination including categorizing the incident based on damage determined from the data. The processor may also identify a responding party based on the incident response and the category of the incident. The processor may further parse the data to generate a set of critical data. The critical data may be based on the responding party. The processor may transmit a message to the responding party including the critical data and the location of the vehicle.

Abstract: Compositions and methods for treating short bowel syndrome in a subject are provided. A viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding a GLP-2 receptor agonist fusion protein and regulatory sequences which direct expression thereof.

Abstract: An example operation may include one or more of receiving a software update at a transport of a subset of transports, validating the software update based on one or more of: a period of time when the software update is in use, and a number of utilizations of the software update by the subset of the transports, propagating the software update based on the validating, to a further subset of transports, wherein the further subset of the transports is larger than the subset of the transports.

Abstract: A water containment system has: a peripheral dam formed of one or more arcuate longitudinal wall sections that are configured to be secured in an assembled position in use around a water tank as the water tank rests on a ground surface, the peripheral dam defining an open water-tank-receiving base; and a drain port defined in the peripheral dam. In a method of retrofitting a water containment system around a water tank, the method includes: assembling a peripheral dam, formed of one or more arcuate longitudinal wall sections around the water tank as the water tanks rests on a ground surface; securing the peripheral dam to the ground surface; and connecting a drain line from a drain port in the peripheral dam to a drain.

Abstract: A material for separating and pumping oxygen is disclosed. The material is a zeolite doped with a chemical element having an electron density of between 30 kJ/mol and 150 kJ/mol. The material is configured for controllable oxygen desorption between 150° C. and 300° C. and pumping the released oxygen into an area having an ambient pressure of less than 100 pascals.

Abstract: An edge shield for reducing electrical current crowding of a wafer, having a first side and a second side, during jet array electroplating, including one or more rings disposed below a second side of the wafer and configured to restrict current flow to an edge of the wafer, and at least one opening configured to allow electrolyte flow to pass through. Further, a system for reducing electrical current crowding of a wafer during jet array electroplating, including a chamber where, when the wafer is placed inside the chamber, there is a first gap between a wall of the chamber and an edge of the wafer and a second gap between a jet array and the second side of the wafer, and an edge shield disposed in the second gap, wherein the edge shield includes at least one opening configured to allow electrolyte flow to escape the chamber.

Abstract: Compositions and methods for treating hypoparathyroidism in a subject are provided. A viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding a PTH fusion protein and regulatory sequences which direct expression thereof.

Abstract: A device for fluorescence-based imaging and monitoring of a target is provided. The device includes a light source emitting light for illuminating the target, the emitted light including at least one wavelength or wavelength band causing at least one biomarker associated with the target to fluoresce, and a light detector for detecting the fluorescence.

Abstract: An incident management system for managing an incident response may be provided. The incident management system may include an incident management (IM) computing device and a vehicle. The IM computing device may include a processor and memory, the processor may be programmed to receive a notification that an incident has occurred, the notification including sensor data and sub-system data. The processor may analyze the data to determine an incident response, the determination including categorizing the incident based on damage determined from the data. The processor may also identify a responding party based on the incident response and the category of the incident. The processor may further parse the data to generate a set of critical data. The critical data may be based on the responding party. The processor may transmit a message to the responding party including the critical data and the location of the vehicle.

Abstract: Described are systems and methods to reduce image flickering of a webcam of an information handling system. The webcam includes a photochromic lens that changes translucency based on UV radiation that is received. Image flickering can be caused when high UV radiation from a strong light source is observed. In passive method, the photochromic lens darkens as high UV radiation is received, and light received by the sensor of the webcam is reduced, which leads to lower shutter speed that reduces image flicker. In active methods, the image signal processor or an application is used to detect image flicker. UV emitters included in the webcam provide the UV radiation to cause the photochromic lens to darken.

Abstract: A sample and related kit and method of treatment including bodily fluid from a patient and proadrenomedullin (proADM) or fragment(s) thereof wherein said proADM) or fragment(s) thereof have been labeled with a luminescence molecule. The patient is an ICU patient, has been diagnosed as being critically ill, and wherein ICU medical treatment has been initiated. The critically ill patient is a patient diagnosed with an infectious disease, and/or is a posttraumatic or postsurgical patient. The level of proADM or fragment(s) thereof in said sample is below 2.25 nmol/l.