Abstract: A rapid exchange microcatheter for accessing the intracranial neurovasculature. A side opening through the sidewall is located a first distance proximal to the distal-most tip. A proximal opening located proximal to the side opening is a second distance from the distal-most tip. A distal, reinforced catheter portion extends between a distal end region to a point near the side opening. A proximal, reinforced catheter portion extends a distance from a point near the side opening towards the proximal end of the catheter body. The side opening is positioned within a gap between a proximal end of the distal reinforced catheter portion and a distal end of the proximal reinforced catheter portion. A payload of a cerebral treatment device is housed within the lumen proximal to the side opening. Related devices, systems, and methods are disclosed.

Abstract: Disclosed herein is a refined PUFA oil with an enhanced palatability comparing to the same PUFA oil without refinement. Also disclosed is a food composition for a companion animal or a food for human consumption wherein said food composition comprises the above refined PUFA oil and thus having enhanced palatability. Further disclosed herein is a method for manufacturing the above-mentioned refined PUFA oil wherein said method comprises the step of deodorization.

Abstract: A hanger (200) is provided for supporting a load on a threaded object (10) with a longitudinal axis. The hanger (200) can include a hanger body (202), a hole (210) in the hanger body (202), and a partial thread portion (212). The hole (210) can be configured to receive the threaded object (10) therethrough. The partial thread portion (212) can be configured to engage with a thread of the threaded object (10) when the hanger (200) is in an engaged configuration. The hanger (200) can be configured to move from a non-engaged configuration to the engaged configuration without rotation of the hanger body (202) or the threaded object (10) about the longitudinal axis of the threaded object (10).

Abstract: A dual motor drive assembly comprising a housing, a shaft rotatably mounted to the housing, a first gear rotatably connected to the shaft, first and second motors, each having an output driving a respective output gear, the output gears being engaged with the first gear, a torque allocation arrangement for allocating torque demands to each of the first and second motors, a measurement arrangement for measuring first and second temperature relating to the first and second motors respectively, a torque limit allocation arrangement for allocating a maximum torque limit based on the first and second temperature respectively, wherein a maximum total torque is equal to the sum of maximum torque limits of the first and second motors, wherein in a first mode the allocated torque demand to each of the motors is to provide opposing torques to the shaft, and in a second mode to provide torques in the same direction to the shaft, wherein the torque demand allocations change from the first mode to the second mode at a thr

Abstract: Mechanisms for dispensing items such as medications and medical supplies. Different mechanisms may be tailored to dispensing different kinds of items, for example medications in single dose packages, vials, syringes, or other similarly-shaped items. The dispensers may be placed in a dispensing unit that includes a lockable restock drawer and a dispense drawer into which items are dispensed by the dispensing mechanisms. The various kinds of dispensing mechanisms may be installed in the restock drawer in any workable proportion and arrangement. The dispensing mechanisms include multiple sensing technologies for tracking and inventory of items and for accurate sensing of items as they are dispensed.

Abstract: An environmentally friendly peg hook made from a paper based material that can be used on a display. The paper material can be recycled or is degradable in a land fill. The peg hook includes an anchor structure for securing the peg hook to a wall of a display through a slot in the wall. The peg hook can include a single hook structure or multiple hook structures in a single row or multiple rows.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive, via a first carrier, an indication of an offset for scheduling a reference signal on a second carrier, wherein the offset indicates a duration between downlink control information (DCI), that schedules the reference signal, and the reference signal; determine a first numerology of the first carrier and a second numerology of the second carrier; and determine a time offset for the reference signal based at least in part on the offset and at least one of the first numerology, the second numerology, or both the first numerology and the second numerology. Numerous other aspects are provided.

Abstract: The present invention relates to monoclonal anti-interleukin-23 receptor (IL-23R) antibodies, nucleic acids and expression vectors encoding the antibodies, recombinant cells containing the vectors, and corresponding compositions and methods of making and using antibodies respectively, i.e., e.g., detecting, selecting, enriching, inhibiting, or antagonizing IL-23R or treat an autoimmune or inflammatory diseases or disorders.

Abstract: Compositions and methods for killing or inhibiting the growth of pathogenic fungi. A composition includes water, a solubilizer, and an essential oil extracted from one or more of lemongrass, cassia, eucalyptus, ajowan, clove leaf, or oregano.

Abstract: A modular manifold system is disclosed. The system includes a first manifold body and a second manifold body configured to couple to the first manifold body via an attachment assembly. Each manifold body includes at least one end port to fluidly communicate with an interior cavity of each manifold body, where each manifold body includes an inlet end port and an outlet end port to transfer a fluid through the respective interior cavity. At least one of the first modular body or the second manifold body includes a valve port in fluid communication with the interior cavity of a respective modular manifold body. The system further includes a hose assembly coupled to one of the first manifold body or the second manifold body via the attachment assembly.

Abstract: An end-to-end mechanism is disclosed herein for transporting encrypted messages over hypertext transport protocol (HTTP) sent to a group of recipients. In particular, the disclosed mechanism receives a message (e.g., as an input from a user) and encrypts that message using an encryption mechanism with a key unique to a particular user and to the message (e.g., different messages are encrypted using different keys). The encrypted message is then stored in a generated object along with other metadata needed for message processing. Once the object is generated, it is signed and encoded into a binary representation that is then sent to a server. The server system receives the binary representation and decodes it back into the object. The metadata of the object is then used to route the message to the correct recipient applications for decryption.

Abstract: A system and method for determining a position of viewed object is disclosed. The system includes a head/eye tracker configured to sense at least one gaze target in an environment corresponding to a gaze of an eye or head of a first operator and at least one remote object sensor configured to sense an object corresponding to the gaze target. The system further includes at least one controller in communication with the head/eye tracker and the remote object sensor configured to receive gaze target data, transmit commands to the remote object sensor to steer transmission beams toward the viewed object based on the gaze target data, wherein a reflection of the steered transmission beams from the object is received by a receiver, receive reflection data from the receiver, generate object position data based on the reflection data, and transmit the object position data.

Abstract: Disclosed are high-throughput vessel receiving systems and methods of receiving sample vessels, such as samples stored in test tubes. A system for receiving a plurality of individual vessels that each contains a sample, and systems and apparatus for guiding, reorienting, collecting, and transporting a plurality of articles, including vessels, are disclosed.

Abstract: Provided is a recombinant adeno-associated virus (rAAV) having an AAVhu68 capsid and a vector genome which comprises a nucleic acid sequence encoding a functional human arylsulfatase A (ARSA). Also provided are a production system useful for producing the rAAV, a pharmaceutical composition comprising the rAAV, and a method of treating a subject having metachromatic leukodystrophy, or ameliorating symptoms of metachromatic leukodystrophy, or delaying progression of metachromatic leukodystrophy via administrating an effective amount of the rAAV to a subject in need thereof.

Abstract: Disclosed herein are compounds and compositions having potency in the modulation of Myc family proteins. Such compounds and compositions can be used in the treatment of proliferative diseases, such as cancer, or in the treatment of disease where modulation of Myc family proteins is desired. Also disclosed herein are methods of using said compounds and compositions.

Abstract: The described methods and systems enable automatic detection of a driver's identity based on an analysis of position or orientation data pertaining to elements of a cockpit that the driver tends to personalize when driving according to her preferences. Example position or orientation data may include data pertaining to seat or mirror position or orientation. Some of the disclosed embodiments utilize machine-learning techniques to train a machine-learning (ML) model to automatically detect or predict a driver's identity based on learned patterns (e.g., based on preferred positions or orientations the ML model has learned for the driver.) If desired, one or more embodiments may implement unsupervised learning techniques, supervised learning techniques, or both unsupervised and supervised learning techniques.

Abstract: A computer-implemented method for detecting and managing burnout risk in a contact center associated with an enterprise.

Abstract: Embodiments of the disclosure relate to a method of controlling tension on a buffer tube produced on a buffer tube processing line. In the method, the buffer tube is directed through a compression caterpillar. A speed of and a gap between drive belts of the compression caterpillar are set to achieve a desired tension on the buffer tube. Tension on the buffer tube is measured as the buffer tube passes between the drive belts. It is determined whether the measured tension on the buffer tube is within an acceptable range, and the gap between the drive belts is decreased in increments while the buffer tube passes between the drive belts until the tension is within the acceptable range.

Abstract: Embodiments described herein, inter alia, receive telematics data collected over a period of time, wherein the telematics data is indicative of operation of a vehicle by a potential renter during the period of time; identify, upon analyzing the telematics data, driving behavior(s) of the renter during the period of time; determine, for each driving behavior, a corresponding state of an environment of the vehicle when the driving behavior occurred; determine renter eligibility value(s) for the renter based on the driving behavior(s) and the corresponding state of an environment of the vehicle; compare the renter eligibility value(s) to user preference value(s) of a profile of a vehicle owner, wherein the user preference value(s) define one or more criteria for vehicle renters with whom the vehicle can be shared; and cause an indication of the vehicle associated with the profile to be displayed only if the renter satisfies the criteria.

Abstract: Systems and methods are provided. A method includes obtaining, by one or more computing devices, one or more work instructions associated with a proof-of-work protocol. The method includes performing, by the one or more computing devices, one or more first tasks based at least in part on the work instructions. The method includes determining, by the one or more computing devices and based on one or more values generated by the one or more computing devices during the one or more first tasks, one or more random or pseudorandom values. The method includes performing, by the one or more computing devices and based on the one or more random or pseudorandom values, one or more second tasks different from the one or more first tasks.