Abstract: An apparatus for decoding a sequence of pictures from a data stream is configured for decoding a picture of the sequence by deriving a residual transform signal of the picture from the data stream; combining a residual transform signal with a buffered transform signal approximation of a previous picture of the sequence so as to obtain a transform signal representing the picture, the transform signal having a plurality of transform coefficients; and subjecting the transform signal to a spectral-to-spatial transformation. The apparatus is configured for deriving the buffered transform signal approximation from a further transform signal representing the previous picture so that the buffered transform signal approximation has approximations of further transform coefficients of the further transform signal.

Abstract: A mixture contains at least one polyether block amide (PEBA) and at least one poly(meth)acrylate, selected from poly(meth)acrylimides, poly-alkyl(meth)acrylates, and mixtures thereof. The mass ratio of PEBA to poly(meth)acrylate is 95:5 to 60:40. The polyalkyl(meth)acrylate contains 80% by weight to 99% by weight of methyl methacrylate (MMA) units and 1% by weight to 20% by weight of C1-C10-alkyl acrylate units, based on the total weight of polyalkyl(meth)acrylate. The mixture can be processed to give foamed mouldings. The mouldings can be used in footwear soles, stud material, insulation or insulating material, damping components, lightweight components, or in a sandwich structure.

Abstract: An apparatus for decoding a sequence of pictures from a data stream is configured for decoding a picture of the sequence by deriving a residual transform signal of the picture from the data stream; combining a residual transform signal with a buffered transform signal approximation of a previous picture of the sequence so as to obtain a transform signal representing the picture, the transform signal having a plurality of transform coefficients; and subjecting the transform signal to a spectral-to-spatial transformation. The apparatus is configured for deriving the buffered transform signal approximation from a further transform signal representing the previous picture so that the buffered transform signal approximation has approximations of further transform coefficients of the further transform signal.

Abstract: Described herein are Mpro cysteine protease inhibitors and methods of utilizing such inhibitors in the treatment of diseases, disorders, or conditions. Also described herein are pharmaceutical compositions containing such compounds.

Abstract: A method for retraining a video monitoring device 1, wherein the video monitoring device 1 is provided with monitoring data 2, wherein the monitoring data 2 comprise images of a monitored region, wherein the monitoring data 2 are processed and/or analysed on at least two processing paths 5a,b, wherein the processing and/or analysis of the monitoring data 2 on the processing paths 5a,b each deliver a path result and an associated reliability measure, wherein at least one of the processing paths 5a,b forms an AI processing path, wherein the AI processing path is based on a neural network and is designed for object detection and/or object classification, wherein a difference between the reliability of the path result of the AI processing path and the reliability of the associated path results of the further processing paths 5a,b and/or a difference between the path result of the AI processing path and the path results of the further processing paths 5a,b is determined, wherein, if a threshold difference is excee

Abstract: A concept for coding a CFA pattern image is provided, wherein, for each of the sample clusters of the CFA pattern image, having first to fourth sample positions, first to fourth color coordinates are computed, so as to provide an image representation of the CFA pattern image.

Abstract: The present invention generally relates to antibodies that bind to CD3 and CD19, e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

Abstract: The present invention generally relates to antibodies that bind to CD3, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

Abstract: The present invention relates to glycosylation patterns at the Fab portion of a monoclonal antibody and methods for the regulation during culture of a microorganism expressing a monoclonal antibody with regulated content of high mannose Fab glycoforms.

Abstract: An ion-jet electron-entangled pathogens analyzer imprinted on a test strip resembles the functionality of a scanning tunneling microscope as a hand-held device, to quickly detect pathogens in water and food products on their bioelectrical signature. The use of such a device does not require special training or preparation. The test strip consists of an integrated circuit which gets energized and communicates over a weak alternating electric field provided by a matchbox-sized base station, which also contains a trained machine learning module of bioelectrical pathogen signatures. The base station connects wirelessly to smart devices or networks for further processing or recording the measurement results in a blockchain. The base station can be worn as a smartwatch or attached to processing machines, transportation vehicles, warehouses, shelves and grocery stores.

Abstract: Described herein are Mpro cysteine protease inhibitors and methods of utilizing such inhibitors in the treatment of diseases, disorders, or conditions. Also described herein are pharmaceutical compositions containing such compounds.

Abstract: The present invention generally relates to antibodies that bind to CD3 and CD19, e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

Abstract: The present invention generally relates to antibodies that bind to CD3, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

Abstract: Herein is reported a method for selecting an antibody with a systematic clearance in cynomolgus monkeys of less than 8 mL/kg/day comprising the steps of measuring the retention time of the antibody on performing an FcRn affinity chromatography with a positive linear pH gradient and on a heparin affinity chromatography with a positive linear conductivity/salt gradient, and selecting an antibody that has a relative retention time on the FcRn affinity chromatography column is less than 1.78 times the retention time difference between peaks 2 and 3 the retention time of preparation of an oxidized anti-Her3 antibody of SEQ ID NO: 03 and 04, and a relative retention time on the heparin affinity chromatography column is less than 0.87 times the retention time of an anti-pTau antibody of SEQ ID NO: 01 and 02.

Abstract: Described herein are Mpro cysteine protease inhibitors and methods of utilizing such inhibitors in the treatment of diseases, disorders, or conditions. Also described herein are pharmaceutical compositions containing such compounds.

Abstract: Disclosed is a system for interacting with polyisoprene based products to enhance sensing features. The system includes a hub unit and one or more electronic circuitries operably configured with the polyisoprene based product. The hub unit includes a controller for contactless powering and communicating data with the polyisoprene based product, a generator for generating a frequency, a resonator for increasing voltage level of the frequency, a first electrode for emitting the alternating electric field, a second electrode for receiving the alternating electric field from the polyisoprene based product, an analog digital converter connected to the second electrode to digitize information received from the polyisoprene based product under the influence of the alternating electric field. The one or more electronic circuitries senses the condition of the polyisoprene based product and communicates further to the hub unit for processing and communicating processed information over a communication network.

Abstract: The present invention generally relates to antibodies that bind to CD3, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

Abstract: Herein is reported a method for selecting an antibody with a systematic clearance in cynomolgus monkeys of less than 8 mL/kg/day comprising the steps of measuring the retention time of the antibody on performing an FcRn affinity chromatography with a positive linear pH gradient and on a heparin affinity chromatography with a positive linear conductivity/salt gradient, and selecting an antibody that has a relative retention time on the FcRn affinity chromatography column is less than 1.78 times the retention time difference between peaks 2 and 3 the retention time of preparation of an oxidized anti-Her3 antibody of SEQ ID NO: 03 and 04, and a relative retention time on the heparin affinity chromatography column is less than 0.87 times the retention time of an anti-pTau antibody of SEQ ID NO: 01 and 02.

Abstract: Disclosed is a SmartDust system for contactless digital controlled serialized analog processing of analog values received from an object. The SmartDust system includes a hub unit and at least one electronic circuitry capacitive coupled to the hub unit. The hub unit includes an oscillator for generating a frequency, and a first electrode connected to the oscillator to emit the frequency as an alternating electric field. The electronic circuitry stores and performs switching instructions and the digital logic operations. The electronic circuitry receives analog values and generate sampled and processed analog values. The electronic circuitry provides the processed values to external components. The hub unit includes a controller for providing the switching instructions and the digital logic operations to the electronic circuitry, and a modulator for modulating the alternating electric field with the switching instructions and the digital logic operations.

Abstract: The present invention generally relates to antibodies that bind to CD3, including multi specific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.