Abstract: Disclosed is a system for interacting with polyisoprene based products to enhance sensing features. The system includes a hub unit and one or more electronic circuitries operably configured with the polyisoprene based product. The hub unit includes a controller for contactless powering and communicating data with the polyisoprene based product, a generator for generating a frequency, a resonator for increasing voltage level of the frequency, a first electrode for emitting the alternating electric field, a second electrode for receiving the alternating electric field from the polyisoprene based product, an analog digital converter connected to the second electrode to digitize information received from the polyisoprene based product under the influence of the alternating electric field. The one or more electronic circuitries senses the condition of the polyisoprene based product and communicates further to the hub unit for processing and communicating processed information over a communication network.

Abstract: Herein is reported a method for providing a modified antibody with improved in vivo half-live, comprising the modification of the Fc-region of the antibody by introducing one or more mutations that change the binding of the Fc-region to human FcRn until the (relative) retention time of the modified antibody in an FcRn affinity chromatography is increased for more than 1 minute but not more than 5 minutes compared to the parent antibody.

Abstract: An ion-jet electron-entangled pathogens analyzer imprinted on a test strip resembles the functionality of a scanning tunneling microscope as a hand-held device, to quickly detect pathogens in water and food products on their bioelectrical signature. The use of such a device does not require special training or preparation. The test strip consists of an integrated circuit which gets energized and communicates over a weak alternating electric field provided by a matchbox-sized base station, which also contains a trained machine learning module of bioelectrical pathogen signatures. The base station connects wirelessly to smart devices or networks for further processing or recording the measurement results in a blockchain. The base station can be worn as a smartwatch or attached to processing machines, transportation vehicles, warehouses, shelves and grocery stores.

Abstract: Disclosed is a system for allowing a user to control electrical items. The system includes self-powered contactless one or more switches for controlling the electronic items, and a hub unit capacitively coupled to identify the user operating the one or more switches. The hub unit includes a frequency generator, a first impedance unit, a controller, a first electrode, a modulator, and an interface unit. The switch includes a second electrode, a rectifier, a buffer, a second impedance unit, a logic block, a shift register, and a second modulator. The user interacts with the second electrode to operate the connected electrical items. The interaction results in the change of a variable payload data. The controller identifies the interaction on decoding the change in the variable payload data and further the controller operates the connected electrical items.

Abstract: The present invention generally relates to antibodies that bind to CD3 and CD19, e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

Abstract: The present invention generally relates to antibodies that bind to CD3, including multi specific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

Abstract: Disclosed is a system for allowing a user to control electrical items. The system includes self-powered contactless one or more switches for controlling the electronic items, and a hub unit capacitively coupled to identify the user operating the one or more switches. The hub unit includes a frequency generator, a first impedance unit, a controller, a first electrode, a modulator, and an interface unit. The switch includes a second electrode, a rectifier, a buffer, a second impedance unit, a logic block, a shift register, and a second modulator. The user interacts with the second electrode to operate the connected electrical items. The interaction results in the change of a variable payload data. The controller identifies the interaction on decoding the change in the variable payload data and further the controller operates the connected electrical items.

Abstract: Disclosed is a novel hybrid of a device combined with independent integrated multi sensing automats that measures up to 64 different vital signs simultaneously and battery free(!). This device includes a glue-free suction patch, easy to attach to a patient's neck, wrists, temples (or selected body parts, if required). A base station contains electronic parts that provide a weak alternating electric field (AeF), which propagates over the patient's skin with no harm, to power and communicate with the suction patch. The electric field is bi-directionally data-modulated (proprietary phase-duplex) while remotely powering the chip at the same time. The suction patch gets a sequence from the base station to create desired vital signs sensors temporarily on-the-fly and sends the digitized sensing values radiation-free(!) continuously to the base station, which wirelessly connects to networks, computers, SmartDevices and applications.

Abstract: Disclosed is a system for allowing users to capacitively interact with objects using gestures in an environment. The system includes a smart sense unit for communicating gesture information and a smart sensing master unit is capacitively coupled to the smart sense unit for identifying the received gesture information and identification information from the smart sense unit to operate the object. The gestures may either be 2D, 3D, multiple 2D or 3D gestures from different users or different body parts. The smart sense unit identifies the change in a provided electric field caused by the user and the object and converts into a digital value. The smart sense unit further identifies the location of the object and the user and further communicates the information to the smart sensing master unit. The smart sensing master unit identifies the gesture and the identification information to interact with the object on receiving the impedance changes forked out from a resonator.

Abstract: An electronic system for triggering and transporting conditional information from a user or an item, the system comprising at least one each of electronic circuit, carrier, rectifier, buffer, source, level shifter, system clock, sync unit, communication unit, interpreter and/or bidirectional interface; a set of electrodes for recognizing 3D-gestures of a user and at least one bidirectional integrated display, wherein sync unit synchronizes the electronic circuit with the source by briefly (e.g. for 1 millisecond) interrupt alternating electric charges and/or sound waves and/or vibrations, and/or also reacts to changes caused by external modulation and bringing logic elements into a defined state and separates the clock from data for facilitating introduction of information, data or commands into the electronic circuit and interpreter interprets received information or data into the electronic circuit as commands and forwards them over level shifter to the interface to operate the integrated (e.g.

Abstract: The present invention provides methods, compositions, devices, and kits for treating cystinuria and related disorders, in which bucillamine is administered to a patient according to a modified-release strategy that releases bucillamine, preferably in the stomach, in critically-spaced, repeated pulses over time, to provide lower peak plasma levels of total bucillamine, but consistently higher free drug levels in urine, for binding cystine. In particular, use of the present modified-release formulations and systems reduce side effects of bucillamine and achieve efficacy with less frequent administrations and/or lower dosage than immediate-release forms.

Abstract: A wet and dry vacuum cleaner having a vacuum cleaner head, having a dirt container and having an inlet fitting which is designed for the connection of a suction hose, wherein the inlet fitting is connected in terms of flow to an inlet connector, which is situated in the wet and dry vacuum cleaner, of the wet and dry vacuum cleaner such that dirt particles that are drawn in can pass via the inlet connector into the dirt container, wherein the inlet connector is designed as a diffuser with horizontal outflow. Furthermore, the inlet connector of the wet and dry vacuum cleaner may have a Y shape in the sense that the inlet connector comprises one inflow opening for the suction flow and two outlet openings.

Abstract: Disclosed is a system for measuring electrical charges propagating through a biological object. The system includes an implantable medical device inserted into the biological object, an electronic implant attached to the implantable medical device for measuring, processing and communicating electrical charges, at least one transponder configured on the implantable medical device to convert mechanical waves into electrical charges, wherein the electrical charges propagate through the biological object to be received by the electronic implant; and an external electronic hub device for providing electrical charges to influence the biological object. The external electronic hub device includes a controller, a frequency generator, a resonator, a filter unit, and an electrode. The electronic implant includes an arrangement of sub-circuits, an energy convertor, an amplifier, an analog/digital converting logic circuit, and a modulator.

Abstract: The present invention provides one or more compounds of formula (I) for conjugation to small molecules, polymers, peptides, proteins, antibodies, antibody fragments etc.

Abstract: Disclosed is an apparatus for battery-free measuring vital signs of a user from a single position near the user influenced by an alternating electric field provided by an electronic device. The apparatus includes a first electronic circuitry, a second electronic circuitry stacked to the first electronic circuitry, an instrumentation amplifier for amplifying the signals, an analog/digital converting logic circuit for generating digitized information, and a communication unit for communicating the digitized information.

Abstract: A roller cutter unit is mountable at a cutting head of undercutting mining machines. The cutter unit includes an elongate mount shaft to position and support a cutter ring. The cutter ring is secured to the mount shaft via a bracket having a wedge segment configured to be wedged axially and radially between the cutter ring and the shaft. Accordingly, a mounting mechanism is provided to achieve a desired force transmission pathway from the cutter ring into the shaft so as to maximize the locking action of the cutter ring at the cutter unit.

Abstract: Techniques for executing one or more instances of a computer program using virtual machines, the computer program comprising multiple computer program portions including a first computer program portion. The techniques include determining whether an instance of any of the multiple computer program portions is to be executed; when it is determined that a first instance of the first computer program portion is to be executed, accessing first information specifying a first set of one or more virtual machine resources required for executing the first instance of the first computer program portion; determining whether any one of the plurality of virtual machines has at least the first set of virtual machine resources available; and when it is determined that a first of the plurality of virtual machines has the first set virtual machine resources available, causing the first virtual machine to execute the first instance of the first computer program portion.

Abstract: Disclosed is a system which extends NFC near field communication over a user's skin by converting electromagnetic signals into modulated alternating electric fields and vice versa. A modified patch is attached to an NFC device, which gets energized from its electromagnetic resonance which may contain data. The patch uses the energy to create an alternating electric field which couples into and spreads over a user's skin. The user may approach or touch objects which then get energized by the alternating electric field. The objects have a tag which modulates the electric field with data back over the user's skin to the patch, which then demodulates the data to modulate the NFC communication of the NFC device for further processing.

Abstract: Disclosed is a system operably connected to a packaging body for controlling a game device console. The system includes a hub unit coupled to the gaming device console and an electronic circuitry communicating with the hub unit. The hub unit includes generator, first convertor, a first electrode, a first switching unit, a first detection unit and a hub controller. The electronic circuitry includes a second electrode, a floating electrode, a second converter, a buffer and a second detection unit for detecting change in electric-field percentage value for playing a game on the gaming device console. The hub controller receives the unique command for a specified electric-field percentage value. Further, the hub controller facilitates in selecting the right game move for playing a game on the gaming device console.

Abstract: The present invention generally relates to antibodies that bind to CD3, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.