Patents by Inventor Xavier Thomas

Xavier Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12214088
    Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one polymer and at least additive.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: February 4, 2025
    Assignees: LTS LOHMANN THERAPIE-SYSTEME AG, DDP SPECIALTY ELECTRONIC MATERIALS US 9, LLC
    Inventors: Marco Emgenbroich, Eva-Marie Prinz, Elke Klein, Heike Kluth, Xavier Thomas, Linda Sue Nartker
  • Patent number: 12168074
    Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one silicone polymer.
    Type: Grant
    Filed: January 11, 2023
    Date of Patent: December 17, 2024
    Assignees: LTS LOHMANN Therapie-Systeme AG, DDP Specialty Electronic Materials US 9, LLC
    Inventors: Marco Emgenbroich, Eva-Marie Prinz, Elke Klein, Heike Kluth, Xavier Thomas, Linda Sue Nartker
  • Patent number: 12048770
    Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one silicone acrylic hybrid polymer.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: July 30, 2024
    Assignees: LTS LOHMANN THERAPIE-SYSTEME AG, DOW SILICONES CORPORATION
    Inventors: Marco Emgenbroich, Eva-Marie Prinz, Elke Klein, Heike Kluth, Xavier Thomas, Linda Sue Nartker
  • Patent number: 11576874
    Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one silicone polymer.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: February 14, 2023
    Assignees: LTS LOHMANN Therapie-Systeme AG, DDP Specialty Electronic Materials US 9, LLC
    Inventors: Marco Emgenbroich, Eva-Marie Prinz, Elke Klein, Heike Kluth, Xavier Thomas, Linda Sue Nartker
  • Publication number: 20210177726
    Abstract: A polyurethane-polyorganosiloxane copolymer is useful as a film forming agent in personal care compositions, such as hair care compositions and skin care compositions.
    Type: Application
    Filed: August 18, 2017
    Publication date: June 17, 2021
    Inventors: Bizhong Zhu, Martin Grasmann, Vinita Pandit, Xavier Thomas
  • Publication number: 20210022985
    Abstract: A siloxane-urethane-urea copolymer is useful as a film forming agent. The copolymer can be added to personal care compositions, including skin care compositions and hair care compositions.
    Type: Application
    Filed: August 18, 2017
    Publication date: January 28, 2021
    Inventors: Bizhong Zhu, Martin Grasmann, Vinita Pandit, Xavier Thomas
  • Patent number: 10316228
    Abstract: A multi-phase silicone acrylic hybrid visco-elastic composition prepared by polymerizing an ethylenically unsaturated monomer and a silicon-containing pressure sensitive adhesive composition comprising acrylate or methacrylate functionality in a first solvent in the presence of an initiator, removing the first solvent, and adding a second solvent to form the multi-phase silicone acrylic hybrid visco-elastic composition. Alternatively, a multi-phase silicone acrylic hybrid visco-elastic composition prepared by polymerizing an ethylenically unsaturated monomer and a silicon-containing pressure sensitive adhesive composition comprising acrylate or methacrylate functionality in a first solvent in the presence of an initiator, adding a processing solvent having a higher boiling point than the first solvent, applying heat to selectively remove a majority of the first solvent, removing the processing solvent, and adding a second solvent to form the multi-phase silicone acrylic hybrid visco-elastic composition.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: June 11, 2019
    Assignee: DOW SILICONES CORPORATION
    Inventors: Chana Wilson Evans, Robert O. Huber, Linda S. Nartker, Gerald K. Schalau, II, Xavier Thomas, Simon Toth
  • Publication number: 20180002583
    Abstract: A multi-phase silicone acrylic hybrid visco-elastic composition prepared by polymerizing an ethylenically unsaturated monomer and a silicon-containing pressure sensitive adhesive composition comprising acrylate or methacrylate functionality in a first solvent in the presence of an initiator, removing the first solvent, and adding a second solvent to form the multi-phase silicone acrylic hybrid visco-elastic composition. Alternatively, a multi-phase silicone acrylic hybrid visco-elastic composition prepared by polymerizing an ethylenically unsaturated monomer and a silicon-containing pressure sensitive adhesive composition comprising acrylate or methacrylate functionality in a first solvent in the presence of an initiator, adding a processing solvent having a higher boiling point than the first solvent, applying heat to selectively remove a majority of the first solvent, removing the processing solvent, and adding a second solvent to form the multi-phase silicone acrylic hybrid visco-elastic composition.
    Type: Application
    Filed: February 5, 2016
    Publication date: January 4, 2018
    Inventors: Chana Wilson Evans, Robert O. Huber, Linda S. Nartker, Gerald K. Schalau, II, Xavier Thomas, Simon Toth
  • Publication number: 20160220497
    Abstract: The invention relates to a method for the therapeutic treatment of keratinous substrate, mucous membrane or tooth comprising preparing a composition containing water, at least one therapeutically active ingredient, an organopolysiloxane X having at least two silicon-bonded alkenyl groups per molecule, a hydrosilylation catalyst and an organohydrogensiloxane compound Y having at least two silicon bonded hydrogen atoms per molecule. At least one of compound X or Y is enclosed within microcapsules suspended in an aqueous phase, and the composition is applied in a galenic form preferably chosen from spray, foam, brush, pen or roller so that a hydrosilylation reaction between compounds X and Y occurs to form a film on the keratinous substrate, mucous membrane or tooth. The invention further extends to a delivery system and to a film comprising a cured silicone.
    Type: Application
    Filed: June 17, 2013
    Publication date: August 4, 2016
    Inventors: Virginie Caprasse, Andre Colas, Fabrizio Galeone, Arnaud Labrosse, Leon Marteaux, Anke Sieg, Xavier Thomas
  • Patent number: 9096721
    Abstract: The invention relates to silicone containing compositions able to form adhesive films on substrates, which typically comprises a curable silicone composition comprising components (a), (d) and at least one of (b) or (c): a. a polyorganosiloxane resin, composed of M and Q units having at least 3 alkenyl groups per molecule, herein after called “SiVi” groups, b. a polyorganosiloxane compound having at least 2 Si-bonded hydrogen groups on the polysiloxane chain, hereinafter called “SiH” groups, c. a telechelic polyorganosiloxane compound having terminal Si—H groups, and d. a hydrosilylation catalyst for the reaction of SiH groups with SiVi groups, e. a liquid diluent in an amount of from 0% to maximum 40% by weight of composition said components reacting together by hydrosilylation at a temperature below 400 C when they are brought into contact on a substrate and cure to form a continuous film on the substrate.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: August 4, 2015
    Assignee: Dow Corning Corporation
    Inventors: Jean-Luc Garaud, Guillaume Kergosien, Xavier Thomas
  • Patent number: 8968773
    Abstract: The invention provides: a cross-linkable therapeutic composition comprising a) a saccharide-siloxane copolymer; b) a crosslinking agent; c) one or more active/inactive ingredients; and d) optionally, a solvent, or solvent mixture, wherein the saccharide-siloxane copolymer has the following formula: R2aR1(3-a)SiO—[(SiR2R1O)m-(SiR12O)n]y-SiR1(3-a)R2a that is further formulaically defined and wherein the saccharide-siloxane copolymer is a reaction product of a functionalized organosiloxane polymer and at least one hydroxy-functional saccharide such that the organosiloxane component is covalently linked via a linking group to the saccharide component; films; and methods related thereto. The composition has therapeutic properties. The invention also provides articles of manufacture including topical and transdermal agent delivery patches comprising the novel film-forming composition and/or films.
    Type: Grant
    Filed: May 23, 2007
    Date of Patent: March 3, 2015
    Assignee: Dow Corning Corporation
    Inventors: Xavier Thomas, Virginie Caprasse, Eric Jude Joffre, Csilla Kollar, David Clayton Gantner, Victor A. Raul
  • Patent number: 8907026
    Abstract: The invention provides a cross-linkable composition comprising a saccharide-siloxane copolymer according to a specified structural formula, a crosslinking agent, and, optionally, solvent. Cross-linked polymeric networks, cured coatings, and articles of manufacture formed from the inventive compositions are also provided, as well as processes and methods of manufacturing the inventive cross-linkable compositions and applications thereof.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: December 9, 2014
    Assignee: Dow Corning Corporation
    Inventors: Eric Jude Joffre, Joseph C. McAuliffe, Csilla Kollar, Xavier Thomas, David C Gantner
  • Publication number: 20140242149
    Abstract: Provided in various embodiments are high viscosity, shear-thinning silicone compositions that can be pattern coated directly onto a substrate and silicone compositions having high-density particles suspended in an adhesive gel. The silicone compositions contain a thixotropic additive, such as a hydrogenated vegetable oil. The silicone compositions may be applied on a substrate for use in medical devices or wound dressings.
    Type: Application
    Filed: October 12, 2012
    Publication date: August 28, 2014
    Applicant: Dow Corning Corporation
    Inventors: David Gantner, Roger A. Gibas, Do-Lung Pan, Xavier Thomas, Christine A. Weber
  • Publication number: 20120135225
    Abstract: This invention pertains to a construction consisting of in the order from the outside towards the inside: An occlusive or non occlusive external film layer; a non-curing pressure sensitive adhesive (PSA) that has been blended with a therapeutic concentration of at least one or a combination of cosmetic or pharmaceutical active ingredients; and a silicone gel adhesive that is used as the skin contact layer.
    Type: Application
    Filed: August 3, 2010
    Publication date: May 31, 2012
    Inventors: Andre Colas, Gerald K. Schalau, II, Xavier Thomas
  • Publication number: 20120095109
    Abstract: The invention relates to silicone containing compositions able to form adhesive films on substrates, which typically comprises a curable silicone composition comprising components (a), (d) and at least one of (b) or (c): a. a polyorganosiloxane resin, composed of M and Q units having at least 3 alkenyl groups per molecule, herein after called “SiVi” groups, b. a poly-organosiloxane compound having at least 2 Si-bonded hydrogen groups on the polysiloxane chain, hereinafter called “SiH” groups, c. a telechelic polyorganosiloxane compound having terminal Si—H groups, and d. a hydrosilylation catalyst for the reaction of SiH groups with SiVi groups, e. a liquid diluent in an amount of from 0% to maximum 40% by weight of composition said components reacting together by hydrosilylation at a temperature below 400 C when they are brought into contact on a substrate and cure to form a continuous film on the substrate.
    Type: Application
    Filed: July 2, 2010
    Publication date: April 19, 2012
    Inventors: Jean- Luc Garaud, Guillaume Kergosien, Xavier Thomas
  • Patent number: 8124689
    Abstract: A silicone acrylate hybrid composition includes the reaction product of a silicon-containing pressure sensitive adhesive composition, an ethylenically unsaturated monomer, and an initiator. The silicon-containing pressure sensitive adhesive composition includes acrylate or methacrylate functionality. A method of making the hybrid composition includes polymerizing the ethylenically unsaturated monomer and the silicon-containing pressure sensitive adhesive composition in the presence of the initiator.
    Type: Grant
    Filed: June 6, 2007
    Date of Patent: February 28, 2012
    Assignee: Dow Corning Corporation
    Inventors: Gary Loubert, Timothy P. Mitchell, Xavier Thomas
  • Publication number: 20110046242
    Abstract: The invention relates to silicone containing compositions able to form adhesive films on substrates, which typically comprises a curable silicone formulation containing: (a) a polyorganosiloxane polymer having at least two functional SiVi groups per molecule, each SiVi group containing an alkenyl functionality directly bonded to a silicon atom; (b) a crosslinker polyorganosiloxane compound having at least 3 Si-bonded hydrogen groups or SiH groups per molecule; (c) a chain extender compound which is a telechelic polyorganosiloxane having terminal SiH groups; (d) a hydrosilylation catalyst for the reaction of SiH groups with SiVi groups; (e) with RHV>1.5 wherein RHV is the ratio of the number of SiH moles in (b) and (c) to the number of SiVi moles in (a) and (d), and 0<RHC<0.7 wherein RHC is the ratio of the number of SiH moles in (c) to the number of SiH moles in (b) and (c). Such formulation can cure quickly and can provide good balance between adhesion and tack.
    Type: Application
    Filed: January 16, 2009
    Publication date: February 24, 2011
    Inventors: Jean-Luc Garaud, Guillaume Kergosien, Xavier Thomas
  • Publication number: 20100143421
    Abstract: A process for the production of water-containing silicone rubber device comprising the steps of mixing an external phase comprising an organopolysiloxane polymer having at least two reactive groups per molecule, a water in oil emulsifier and where required one or more active ingredients and/or optional additives; with an internal phase comprising water and optionally one or more active ingredients to form an emulsion; and subsequently introducing a cure package comprising a cure package comprising a suitable catalyst, which will be determined by the cure reaction between the polymer and where required a cross-linker, and which contains more than two reactive groups, designed to react with the reactive groups in the polymer in the presence of said catalyst in order to cure the external phase of the composition, thereby entrapping the water within the body of said water-containing silicone rubber device.
    Type: Application
    Filed: April 10, 2007
    Publication date: June 10, 2010
    Inventors: Isabelle Van Reeth, Virginie Caprasse, Xavier Thomas, Jean-Paul Lecomte, Benedicte Courel, Esternia Schirosi
  • Publication number: 20090258058
    Abstract: The invention provides: a film-forming composition comprising a) a saccharide-siloxane copolymer; b) a crosslinking agent; c) one or more active/inactive ingredients; and d) optionally, a solvent, or solvent mixture, wherein the saccharide-siloxane copolymer has the following formula: R2aR1(3?a)SiO—[(SiR2R1O)m-(SiR12O)n]y-SiR1(3?a)R2a that is further formulaically defined and wherein the saccharide-siloxane copolymer is a reaction product of a functionalized organosiloxane polymer and at least one hydroxy-functional saccharide such that the organosiloxane component is covalently linked via a linking group to the saccharide component; films; and methods related thereto. The invention also provides articles of manufacture including topical and transdermal agent delivery patches comprising the novel film-forming composition and/or films.
    Type: Application
    Filed: May 23, 2007
    Publication date: October 15, 2009
    Applicant: DOW CORNING CORPORATION
    Inventors: Xavier Thomas, Virginie Caprasse, Eric Jude Joffre, Csilla Kollar, David Clayton Gantner, Victor A. Raul
  • Publication number: 20080138386
    Abstract: The invention provides a cross-linkable composition comprising a saccharide-siloxane copolymer according to a specified structural formula, a crosslinking agent, and, optionally, solvent. Cross-linked polymeric networks, cured coatings, and articles of manufacture formed from the inventive compositions are also provided, as well as processes and methods of manufacturing the inventive cross-linkable compositions and applications thereof.
    Type: Application
    Filed: December 22, 2005
    Publication date: June 12, 2008
    Inventors: Eric Jude Joffre, Joseph C. McAuliffe, Csilla Kollar, Xavier Thomas, David C. Gantner