Patents by Inventor Xavier Thomas
Xavier Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12214088Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one polymer and at least additive.Type: GrantFiled: October 11, 2018Date of Patent: February 4, 2025Assignees: LTS LOHMANN THERAPIE-SYSTEME AG, DDP SPECIALTY ELECTRONIC MATERIALS US 9, LLCInventors: Marco Emgenbroich, Eva-Marie Prinz, Elke Klein, Heike Kluth, Xavier Thomas, Linda Sue Nartker
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Patent number: 12168074Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one silicone polymer.Type: GrantFiled: January 11, 2023Date of Patent: December 17, 2024Assignees: LTS LOHMANN Therapie-Systeme AG, DDP Specialty Electronic Materials US 9, LLCInventors: Marco Emgenbroich, Eva-Marie Prinz, Elke Klein, Heike Kluth, Xavier Thomas, Linda Sue Nartker
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Patent number: 12048770Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one silicone acrylic hybrid polymer.Type: GrantFiled: October 11, 2018Date of Patent: July 30, 2024Assignees: LTS LOHMANN THERAPIE-SYSTEME AG, DOW SILICONES CORPORATIONInventors: Marco Emgenbroich, Eva-Marie Prinz, Elke Klein, Heike Kluth, Xavier Thomas, Linda Sue Nartker
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Patent number: 11576874Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one silicone polymer.Type: GrantFiled: October 11, 2018Date of Patent: February 14, 2023Assignees: LTS LOHMANN Therapie-Systeme AG, DDP Specialty Electronic Materials US 9, LLCInventors: Marco Emgenbroich, Eva-Marie Prinz, Elke Klein, Heike Kluth, Xavier Thomas, Linda Sue Nartker
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Publication number: 20210177726Abstract: A polyurethane-polyorganosiloxane copolymer is useful as a film forming agent in personal care compositions, such as hair care compositions and skin care compositions.Type: ApplicationFiled: August 18, 2017Publication date: June 17, 2021Inventors: Bizhong Zhu, Martin Grasmann, Vinita Pandit, Xavier Thomas
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Publication number: 20210022985Abstract: A siloxane-urethane-urea copolymer is useful as a film forming agent. The copolymer can be added to personal care compositions, including skin care compositions and hair care compositions.Type: ApplicationFiled: August 18, 2017Publication date: January 28, 2021Inventors: Bizhong Zhu, Martin Grasmann, Vinita Pandit, Xavier Thomas
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Patent number: 10316228Abstract: A multi-phase silicone acrylic hybrid visco-elastic composition prepared by polymerizing an ethylenically unsaturated monomer and a silicon-containing pressure sensitive adhesive composition comprising acrylate or methacrylate functionality in a first solvent in the presence of an initiator, removing the first solvent, and adding a second solvent to form the multi-phase silicone acrylic hybrid visco-elastic composition. Alternatively, a multi-phase silicone acrylic hybrid visco-elastic composition prepared by polymerizing an ethylenically unsaturated monomer and a silicon-containing pressure sensitive adhesive composition comprising acrylate or methacrylate functionality in a first solvent in the presence of an initiator, adding a processing solvent having a higher boiling point than the first solvent, applying heat to selectively remove a majority of the first solvent, removing the processing solvent, and adding a second solvent to form the multi-phase silicone acrylic hybrid visco-elastic composition.Type: GrantFiled: February 5, 2016Date of Patent: June 11, 2019Assignee: DOW SILICONES CORPORATIONInventors: Chana Wilson Evans, Robert O. Huber, Linda S. Nartker, Gerald K. Schalau, II, Xavier Thomas, Simon Toth
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Publication number: 20180002583Abstract: A multi-phase silicone acrylic hybrid visco-elastic composition prepared by polymerizing an ethylenically unsaturated monomer and a silicon-containing pressure sensitive adhesive composition comprising acrylate or methacrylate functionality in a first solvent in the presence of an initiator, removing the first solvent, and adding a second solvent to form the multi-phase silicone acrylic hybrid visco-elastic composition. Alternatively, a multi-phase silicone acrylic hybrid visco-elastic composition prepared by polymerizing an ethylenically unsaturated monomer and a silicon-containing pressure sensitive adhesive composition comprising acrylate or methacrylate functionality in a first solvent in the presence of an initiator, adding a processing solvent having a higher boiling point than the first solvent, applying heat to selectively remove a majority of the first solvent, removing the processing solvent, and adding a second solvent to form the multi-phase silicone acrylic hybrid visco-elastic composition.Type: ApplicationFiled: February 5, 2016Publication date: January 4, 2018Inventors: Chana Wilson Evans, Robert O. Huber, Linda S. Nartker, Gerald K. Schalau, II, Xavier Thomas, Simon Toth
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Publication number: 20160220497Abstract: The invention relates to a method for the therapeutic treatment of keratinous substrate, mucous membrane or tooth comprising preparing a composition containing water, at least one therapeutically active ingredient, an organopolysiloxane X having at least two silicon-bonded alkenyl groups per molecule, a hydrosilylation catalyst and an organohydrogensiloxane compound Y having at least two silicon bonded hydrogen atoms per molecule. At least one of compound X or Y is enclosed within microcapsules suspended in an aqueous phase, and the composition is applied in a galenic form preferably chosen from spray, foam, brush, pen or roller so that a hydrosilylation reaction between compounds X and Y occurs to form a film on the keratinous substrate, mucous membrane or tooth. The invention further extends to a delivery system and to a film comprising a cured silicone.Type: ApplicationFiled: June 17, 2013Publication date: August 4, 2016Inventors: Virginie Caprasse, Andre Colas, Fabrizio Galeone, Arnaud Labrosse, Leon Marteaux, Anke Sieg, Xavier Thomas
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Patent number: 9096721Abstract: The invention relates to silicone containing compositions able to form adhesive films on substrates, which typically comprises a curable silicone composition comprising components (a), (d) and at least one of (b) or (c): a. a polyorganosiloxane resin, composed of M and Q units having at least 3 alkenyl groups per molecule, herein after called “SiVi” groups, b. a polyorganosiloxane compound having at least 2 Si-bonded hydrogen groups on the polysiloxane chain, hereinafter called “SiH” groups, c. a telechelic polyorganosiloxane compound having terminal Si—H groups, and d. a hydrosilylation catalyst for the reaction of SiH groups with SiVi groups, e. a liquid diluent in an amount of from 0% to maximum 40% by weight of composition said components reacting together by hydrosilylation at a temperature below 400 C when they are brought into contact on a substrate and cure to form a continuous film on the substrate.Type: GrantFiled: July 2, 2010Date of Patent: August 4, 2015Assignee: Dow Corning CorporationInventors: Jean-Luc Garaud, Guillaume Kergosien, Xavier Thomas
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Patent number: 8968773Abstract: The invention provides: a cross-linkable therapeutic composition comprising a) a saccharide-siloxane copolymer; b) a crosslinking agent; c) one or more active/inactive ingredients; and d) optionally, a solvent, or solvent mixture, wherein the saccharide-siloxane copolymer has the following formula: R2aR1(3-a)SiO—[(SiR2R1O)m-(SiR12O)n]y-SiR1(3-a)R2a that is further formulaically defined and wherein the saccharide-siloxane copolymer is a reaction product of a functionalized organosiloxane polymer and at least one hydroxy-functional saccharide such that the organosiloxane component is covalently linked via a linking group to the saccharide component; films; and methods related thereto. The composition has therapeutic properties. The invention also provides articles of manufacture including topical and transdermal agent delivery patches comprising the novel film-forming composition and/or films.Type: GrantFiled: May 23, 2007Date of Patent: March 3, 2015Assignee: Dow Corning CorporationInventors: Xavier Thomas, Virginie Caprasse, Eric Jude Joffre, Csilla Kollar, David Clayton Gantner, Victor A. Raul
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Crosslinkable saccharide-siloxane compositions, and networks, coatings and articles formed therefrom
Patent number: 8907026Abstract: The invention provides a cross-linkable composition comprising a saccharide-siloxane copolymer according to a specified structural formula, a crosslinking agent, and, optionally, solvent. Cross-linked polymeric networks, cured coatings, and articles of manufacture formed from the inventive compositions are also provided, as well as processes and methods of manufacturing the inventive cross-linkable compositions and applications thereof.Type: GrantFiled: December 22, 2005Date of Patent: December 9, 2014Assignee: Dow Corning CorporationInventors: Eric Jude Joffre, Joseph C. McAuliffe, Csilla Kollar, Xavier Thomas, David C Gantner -
Publication number: 20140242149Abstract: Provided in various embodiments are high viscosity, shear-thinning silicone compositions that can be pattern coated directly onto a substrate and silicone compositions having high-density particles suspended in an adhesive gel. The silicone compositions contain a thixotropic additive, such as a hydrogenated vegetable oil. The silicone compositions may be applied on a substrate for use in medical devices or wound dressings.Type: ApplicationFiled: October 12, 2012Publication date: August 28, 2014Applicant: Dow Corning CorporationInventors: David Gantner, Roger A. Gibas, Do-Lung Pan, Xavier Thomas, Christine A. Weber
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Publication number: 20120135225Abstract: This invention pertains to a construction consisting of in the order from the outside towards the inside: An occlusive or non occlusive external film layer; a non-curing pressure sensitive adhesive (PSA) that has been blended with a therapeutic concentration of at least one or a combination of cosmetic or pharmaceutical active ingredients; and a silicone gel adhesive that is used as the skin contact layer.Type: ApplicationFiled: August 3, 2010Publication date: May 31, 2012Inventors: Andre Colas, Gerald K. Schalau, II, Xavier Thomas
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Publication number: 20120095109Abstract: The invention relates to silicone containing compositions able to form adhesive films on substrates, which typically comprises a curable silicone composition comprising components (a), (d) and at least one of (b) or (c): a. a polyorganosiloxane resin, composed of M and Q units having at least 3 alkenyl groups per molecule, herein after called “SiVi” groups, b. a poly-organosiloxane compound having at least 2 Si-bonded hydrogen groups on the polysiloxane chain, hereinafter called “SiH” groups, c. a telechelic polyorganosiloxane compound having terminal Si—H groups, and d. a hydrosilylation catalyst for the reaction of SiH groups with SiVi groups, e. a liquid diluent in an amount of from 0% to maximum 40% by weight of composition said components reacting together by hydrosilylation at a temperature below 400 C when they are brought into contact on a substrate and cure to form a continuous film on the substrate.Type: ApplicationFiled: July 2, 2010Publication date: April 19, 2012Inventors: Jean- Luc Garaud, Guillaume Kergosien, Xavier Thomas
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Patent number: 8124689Abstract: A silicone acrylate hybrid composition includes the reaction product of a silicon-containing pressure sensitive adhesive composition, an ethylenically unsaturated monomer, and an initiator. The silicon-containing pressure sensitive adhesive composition includes acrylate or methacrylate functionality. A method of making the hybrid composition includes polymerizing the ethylenically unsaturated monomer and the silicon-containing pressure sensitive adhesive composition in the presence of the initiator.Type: GrantFiled: June 6, 2007Date of Patent: February 28, 2012Assignee: Dow Corning CorporationInventors: Gary Loubert, Timothy P. Mitchell, Xavier Thomas
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Publication number: 20110046242Abstract: The invention relates to silicone containing compositions able to form adhesive films on substrates, which typically comprises a curable silicone formulation containing: (a) a polyorganosiloxane polymer having at least two functional SiVi groups per molecule, each SiVi group containing an alkenyl functionality directly bonded to a silicon atom; (b) a crosslinker polyorganosiloxane compound having at least 3 Si-bonded hydrogen groups or SiH groups per molecule; (c) a chain extender compound which is a telechelic polyorganosiloxane having terminal SiH groups; (d) a hydrosilylation catalyst for the reaction of SiH groups with SiVi groups; (e) with RHV>1.5 wherein RHV is the ratio of the number of SiH moles in (b) and (c) to the number of SiVi moles in (a) and (d), and 0<RHC<0.7 wherein RHC is the ratio of the number of SiH moles in (c) to the number of SiH moles in (b) and (c). Such formulation can cure quickly and can provide good balance between adhesion and tack.Type: ApplicationFiled: January 16, 2009Publication date: February 24, 2011Inventors: Jean-Luc Garaud, Guillaume Kergosien, Xavier Thomas
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Publication number: 20100143421Abstract: A process for the production of water-containing silicone rubber device comprising the steps of mixing an external phase comprising an organopolysiloxane polymer having at least two reactive groups per molecule, a water in oil emulsifier and where required one or more active ingredients and/or optional additives; with an internal phase comprising water and optionally one or more active ingredients to form an emulsion; and subsequently introducing a cure package comprising a cure package comprising a suitable catalyst, which will be determined by the cure reaction between the polymer and where required a cross-linker, and which contains more than two reactive groups, designed to react with the reactive groups in the polymer in the presence of said catalyst in order to cure the external phase of the composition, thereby entrapping the water within the body of said water-containing silicone rubber device.Type: ApplicationFiled: April 10, 2007Publication date: June 10, 2010Inventors: Isabelle Van Reeth, Virginie Caprasse, Xavier Thomas, Jean-Paul Lecomte, Benedicte Courel, Esternia Schirosi
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Publication number: 20090258058Abstract: The invention provides: a film-forming composition comprising a) a saccharide-siloxane copolymer; b) a crosslinking agent; c) one or more active/inactive ingredients; and d) optionally, a solvent, or solvent mixture, wherein the saccharide-siloxane copolymer has the following formula: R2aR1(3?a)SiO—[(SiR2R1O)m-(SiR12O)n]y-SiR1(3?a)R2a that is further formulaically defined and wherein the saccharide-siloxane copolymer is a reaction product of a functionalized organosiloxane polymer and at least one hydroxy-functional saccharide such that the organosiloxane component is covalently linked via a linking group to the saccharide component; films; and methods related thereto. The invention also provides articles of manufacture including topical and transdermal agent delivery patches comprising the novel film-forming composition and/or films.Type: ApplicationFiled: May 23, 2007Publication date: October 15, 2009Applicant: DOW CORNING CORPORATIONInventors: Xavier Thomas, Virginie Caprasse, Eric Jude Joffre, Csilla Kollar, David Clayton Gantner, Victor A. Raul
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Crosslinkable Saccharide-Siloxane Compositions, and Networks, Coatings and Articles Formed Therefrom
Publication number: 20080138386Abstract: The invention provides a cross-linkable composition comprising a saccharide-siloxane copolymer according to a specified structural formula, a crosslinking agent, and, optionally, solvent. Cross-linked polymeric networks, cured coatings, and articles of manufacture formed from the inventive compositions are also provided, as well as processes and methods of manufacturing the inventive cross-linkable compositions and applications thereof.Type: ApplicationFiled: December 22, 2005Publication date: June 12, 2008Inventors: Eric Jude Joffre, Joseph C. McAuliffe, Csilla Kollar, Xavier Thomas, David C. Gantner