Abstract: Various teachings of the present disclosure include an application program construction method. An example may include: determining a plurality of functional modules constituting an application program; attaching a pre-configured communication component to each functional module; establishing a connection relationship between the functional modules by using the communication components; and storing the connection relationship in a configuration file.

Abstract: Embodiments of the present disclosure provide a data transmission method and apparatus. The method includes: receiving, by user equipment UE, first synchronization source configuration information on a first carrier; determining, a first synchronization source based on the first synchronization source configuration information; determining that synchronization with the first synchronization source fails; determining a second synchronization source and a transmission resource; and transmitting data on a second carrier using the determined transmission resource and based on the second synchronization source, where the first synchronization source is used to provide the UE with a synchronization clock required for transmitting the data on the second carrier, and a frequency of the first carrier is different from a frequency of the second carrier.

Abstract: The present disclosure relates to the field of hydrogel technology, and specifically relates to a small molecule melphalan hydrogel and a preparation method thereof. The small molecule melphalan hydrogel is made of melphalan drug or melphalan hydrochloride as raw materials, and it is formed at room temperature or physiological condition by means of making the melphalan drug in a hydrophilic solvent. The hydrophilic solvent includes any one of physiological saline, pure water, and phosphate buffered saline solution. The small molecule melphalan hydrogel provided by the present disclosure is an injectable hydrogel of 100% pure melphalan drug, the gel only contains small molecule melphalan drug, which solves the problems of containing a large amount of carrier materials and having a low drug loading rate in the field of hydrogel.

Abstract: Provided in the present disclosure are a grating structure, a preparation method thereof and a display device. The preparation method of the grating structure includes: forming a plurality of first convex structures arranged in a first direction; and forming a first rubber material at least covering the plurality of first convex structures, and forming the grating structure including a plurality of second convex structures by using convex structures including the first convex structures and the first rubber material, wherein a surface of the first rubber material facing away from the first convex structures is a flat surface, and the convex structures including the first convex structures and the first rubber material are in one-to-one correspondence with the second convex structures, shapes of cross sections of the second convex structures in the first direction are triangles, and the second convex structures have at least one inclined flat surface.

Abstract: Automatic container image registry selection is provided. A predefined number of top performing container image registries is selected from a top of a sorted list of a plurality of container image registries listed in descending order. A cluster of host nodes where a container is deployed is enabled to pull a same container image corresponding to the container utilizing different predefined pulling percentages from the predefined number of top performing container image registries. The cluster of host nodes utilizes a different predefined pulling percentage to pull the same container image from each respective top performing container image registry. A current real time average pulling speed of the cluster of host nodes for the same container image from each respective top performing container image registry of the predefined number of top performing container image registries is recorded over a defined time period.

Abstract: Provided herein are antibodies, or antigen binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen binding portions thereof.

Abstract: An image processing method is disclosed. The method includes: obtaining an image including a target portrait, where the image includes a foreground and a background, and the target portrait corresponds to the foreground; determining a target hairline from the image, where the target hairline includes a part that overlaps with the background; and performing blur processing on the image to obtain a target image, where the target hairline is blurred to a smaller degree than the background is blurred, and the target portrait is blurred to a smaller degree than the background is blurred. This image processing method may highlight details of a portrait, so that these details, for example a hairline, scattered in a background, are not considered as the background to be blurred, thereby improving the experience of portrait photography.

Abstract: A MEMS gyroscope for three-axis detection relates to the technical field of gyroscope and includes a substrate, a sensing unit elastically connected with the substrate, and a driving unit coupled with the sensing unit and driving the sensing unit to move. The substrate includes anchor point structures respectively located at four corners of the substrate and four coupling structures respectively elastically connected with the four anchor point structures. An avoiding space is formed between two adjacent coupling structures. The driving unit includes two driving pieces separately elastically connected with adjacent coupling structures. The two driving pieces are symmetrically arranged and are frame-shaped. The sensing unit includes four X and Y mass blocks, two Z mass blocks elastically connected with the driving pieces, and two decoupling mass blocks. The two decoupling mass blocks are elastically connected.

Abstract: A multifunctional and visual rock triaxial testing system is provided. The multifunctional and visual rock triaxial testing system includes an axial loading system, a high-energy accelerator computerized tomography (CT) scanning system, a turntable system, a triaxial pressure cell, a fluid fracturing pump, a temperature pump, a confining pressure loading pump, a power oil source, and an integrated control console, where the turntable system is configured to drive the high-energy accelerator CT scanning system to rotate, so as to scan an internal structure of a rock sample; and the triaxial pressure cell and the fluid fracturing pump are configured to conduct compression and fracturing tests on the rock sample, respectively.

Abstract: A large-flux in-situ filtration device for marine microorganism based on a multi-channel circulation distributor is provided, comprising an energy and control module, a circulation distribution module, a filtration module, a pump module, a filtration volume measurement module, a pipeline connection, and a main body support frame. The circulation distribution module may include a multi-channel circulation distributor, a deep-sea servo motor, etc. The filtration module may include a plurality of filter film holders. The pump module may include a stainless steel gear pump, a deep-sea drive motor, etc. The filtration volume measurement module may include a water meter, a camera, and an LED light.

Abstract: A method, computer system, and a computer program product are provided for managing an accelerated shutdown of a networked system having a having a plurality of nodes. The system to be shutdown is analyzed and a priority order is determined for the nodes. An interval period is also determined between each node according to the priority order. A leaf node set is constructed according to different shutdown types required for each node and a dependency tree is constructed by analyzing the leaf node sets. Each node is then shutdown according to the tree and the interval period determined. The dependency tree and the interval period is iteratively modified during the node shutdown until all nodes and ultimately the system shutdown has been completed.

Abstract: An access system for an Internet of Things terminal includes a core network gateway device and an IoT cloud platform, which communicate with each other through a first VPN. The core network gateway device is configured for allocating a first IP address to an IoT terminal, establishing an IoT terminal address pool according to the first IP address, and sending the IoT terminal address pool to the IoT cloud platform. Further, the IoT cloud platform is configured for receiving and storing the IoT terminal address pool, when a first message of a downlink instruction is received, obtaining the first IP address according to the first message and the IoT terminal address pool, and packaging the first message and the first IP address into a second message to be sent to the core network gateway device.

Abstract: A display panel, a method for manufacturing the display panel, and a display apparatus are provided. The display panel includes: a driving backboard including a substrate, a functional circuit and a first electrode electrically connected with the functional circuit; a connection structure located at a side of the driving backboard, the connection structure includes a first connection portion, and the first connection portion includes a first base material and a first connection metal. The first base material is not in contact with the first electrode, the first connection metal is at least partially located on a surface of the first base material away from the substrate, and the first connection metal is electrically connected to the first electrode.

Abstract: The present invention relates to an accelerometer, which comprises a substrate and detecting devices. The substrate is provided with supporting anchor points and electrode fixing anchor points; the detecting device comprises two detecting plates and corresponding detecting electrodes, and the detecting electrodes are connected to the electrode fixing anchor points through connecting arms; the detecting plate is elastically connected to the supporting anchor point, the two detecting plates are asymmetrically arranged with respect to axes of the supporting anchor points, and the two detecting plates are parallel to each other and in opposite directions; and the detecting electrodes and the detecting plates are arranged at intervals to form a detecting capacitor.

Abstract: Described herein are systems, methods, and programming describing various pipelines for determining an immunophenotype of a tumor depicted by a digital pathology image based on immune cell density in the tumor epithelium and/or the tumor stroma and/or spatial information across all or part of the image. One or more machine learning models may be implemented by some or all of the pipelines. The pipelines may include a first pipeline using density thresholds for immunophenotyping, a second pipeline using immune cell density in tumor epithelium and tumor stroma for immunophenotyping, a third pipeline using spatial information of the digital pathology image for immunophenotyping, and a fourth pipeline that combines aspects of the second and third pipelines for immunophenotyping.

Abstract: A micromechanical gyroscope and an electronic device are related. The micromechanical gyroscope includes a first movement member, a second movement member, many drive members and a detection member, the first movement member has a first center, with two ends along a second direction oscillating around the first center along a first and a third directions, the second movement member has a second center, with two ends along the first direction oscillating around the second center along the second and third directions. The drive members can drive oscillations of the first and second movement members. The detection member is located above or below the first and second movement members in the third direction, to detect moving distances of the first and second movement members along the third direction. The micromechanical gyroscope can detect angular velocities in two directions simultaneously and perform differential detection to reduce errors, thus expanding application scenarios.

Abstract: A communications system, method and apparatus, the apparatus configured for determining configuration information of a default data radio bearer (DRB) of a first link, the first link being a direct wireless communications link between a first terminal device and another terminal device, and the first terminal device being a transmit end of a first vehicle-to-everything (V2X) data packet, and sending the configuration information of the default DRB of the first link to the first terminal device, where the configuration information of the default DRB of the first link has first indication information, and the first indication information indicating that the configuration information is the configuration information of the default DRB of the first link.

Abstract: The invention relates to synthetic liver-specific promoters and expression constructs for producing polypeptides and functional nucleic acids in the liver of a subject. The invention further relates to Factor VIII proteins containing modifications in the amino acid sequence of the Factor VIII protein, as well as nucleic acid constructs encoding the Factor VIII proteins and methods of using these compositions to treat a bleeding disorder.

Abstract: The present disclosure provides a measurement method and system based on image electroencephalogram sensitivity data for a built environment dominant color, and relates to the field of urban quality measurement. The measurement method based on image electroencephalogram sensitivity data for a built environment dominant color includes acquiring electroencephalogram data corresponding to a built environment image sample; calculating an environment dominant color sensitivity on the basis of the electroencephalogram data; extracting a dominant color feature parameter according to the built environment image sample; constructing a built environment dominant color measurement model, and training same by taking sensitivity data and a dominant color feature as an input; and inputting an environment image to be analyzed into a trained model, so as to obtain a predicted dominant color sensitivity result.

Abstract: A compound of formula I and a use thereof as an MALT1 inhibitor, and a pharmaceutical composition containing the compound. The compound can be used to treat diseases or disorders such as cancer.