Abstract: A method of manufacturing a display panel and a display panel are provided. A groove is formed on a buffer layer through performing exposure and etching processes, so as to divide the buffer layer into independent units. A gate insulating layer, a dielectric layer, and a passivation layer are converted from continuous layers to independent layers on the buffer layer. Therefore, heterogeneous interface stress accumulated in the independent unit is reduced, it prevents the deformation of the glass substrate, protects the glass substrate, reduces fragmentation phenomenon, and improves process reliability and yield.

Abstract: The present disclosure describes techniques of detecting objects in a video. The techniques comprises extracting features from each frame of the video; generating a first attentive feature by applying a first attention model on at least some of features extracted from any particular frame among the plurality of frames, wherein the first attention model identifies correlations between a plurality of locations in the particular frame by computing relationships between any two locations among the plurality of locations; generating a second attentive feature by applying a second attention model on at least one pair of features at different levels selected from the features extracted from the particular frame, wherein the second attention model identifies a correlation between at least one pair of locations corresponding to the at least one pair of features; and generating a representation of an object included in the particular frame.

Abstract: Provided herein are GLP-1 receptor modulator compounds, pharmaceutical compositions, methods of their preparation, and methods of their use in treatment, and/or diagnosis.

Abstract: A thermal management system includes a refrigerant loop, a motor coolant loop, and a battery coolant loop. The refrigerant loop includes a first refrigerant main-line, a second refrigerant main-line, a first refrigerant branch, and a second refrigerant branch. The first refrigerant main-line includes a compressor, the second refrigerant main-line includes a cabin condenser, the first refrigerant branch includes a cabin evaporator, the second refrigerant branch includes a radiator. The first refrigerant main-line and the second refrigerant main-line selectively communicate with one of the first and second refrigerant branches. The battery coolant loop includes a coolant main-line, a first coolant branch connected to the cabin evaporator, a second coolant branch connected to the cabin condenser, and a third coolant branch. The coolant main-line selectively communicates with at least one of the first to third coolant branches. The battery coolant loop connects to the motor coolant loop in series or in parallel.

Abstract: The present disclosure provides a flat panel detection substrate, a fabricating method thereof and a flat panel detector. The flat panel detection substrate according to the present disclosure includes a base substrate; a bias electrode and a sense electrode on the base substrate; and a semiconductor layer over the bias electrode and the sense electrode, the semiconductor layer having a thickness greater than 100 nm.

Abstract: Embodiments of the present application provide an image display method and apparatus, a device, and a storage medium. The method comprises: displaying a preceding image in a first display period, the preceding image comprising a video image sequence or a single image; superimposing a foreground target area of a succeeding image on an upper layer of the preceding image in a second display period for display, the succeeding image comprising a video image sequence or a single image; and displaying the succeeding image in a third display period. According to the method, a good playback effect can be achieved in scenarios where time variations are desired.

Abstract: Provided are a Multicast Broadcast Single Frequency Network (MBSFN) subframe processing method and apparatus, a base station and user equipment. In the solution, a base station places an MBSFN Reference Signal (RS) in a 0-filling region of an MBSFN subframe for transmission, thus making full use of time frequency resources, and facilitating User Equipment (UE) in performing channel estimation by using the MBSFN RS during reception.

Abstract: A system and method for determining a dimension of a target. The method includes: determining a camera parameter, the camera parameter including at least one of a focal length, a yaw angle, a roll angle, a pitch angle, or a height of one or more cameras; acquiring a first image and a second image of an target captured by the one or more cameras; generating a first corrected image and a second corrected image by correcting the first image and the second image; determining a parallax between a pixel in the first corrected image and a corresponding pixel in the second corrected image; determining an outline of the target; and determining a dimension of the target based at least in part on the camera parameter, the parallax, and the outline of the target.

Abstract: Compositions and methods for enhancing antigen-specific immunity in a subject are provided. Pharmaceutical compositions including an effective amount of an immuno-stimulatory cardiolipin as an adjuvant in combination with an antigen and methods of use thereof for stimulating protective immunity to the antigen in a subject are provided. Administration of the combination of the antigen and cardiolipin adjuvant is effective to enhance antigen-specific immunity in a subject to a greater degree than administering to the subject the same amount of the antigen alone. The active agents can be administered together or separately. In preferred forms the cardiolipin is cardiolipin species (C18:2)4. In preferred forms the antigen is formulated as a vaccine, such as an influenza vaccine. A preferred amount by weight of each reagent is about 10-40% cardiolipin to about 90-60% antigen(s), inclusive.

Abstract: Semantic segmentation techniques and systems are described that overcome the challenges of limited availability of training data to describe the potentially millions of tags that may be used to describe semantic classes in digital images. In one example, the techniques are configured to train neural networks to leverage different types of training datasets using sequential neural networks and use of vector representations to represent the different semantic classes.

Abstract: A voice wake-up method is provided. The method includes: collecting a first voice signal in an environment in which the first electronic device is located; If audio is being played in the environment when the first voice signal is collected, obtaining in a wired or wireless communication manner, an audio signal corresponding to the audio, determining a first false wake-up result based on the first voice signal and the audio signal; receiving a second false wake-up result sent by the second electronic device, determining a third false wake-up result based on the first false wake-up result and the second false wake-up result; wherein the third false wake-up result is used to indicate whether a wake-up operation needs to be performed on a to-be-woken-up device in a local area network; sending the third false wake-up result to another electronic device other than the first electronic device in the local area network.

Abstract: Disclosed is a BIPV module, comprising a stack of a front light-transmitting plate, a power generation layer set, a bus wiring layer and a rear light-transmitting plate, wherein one of the rear light-transmitting plate and the front light-transmitting plate is provided with a pattern layer coated with color glaze at a side thereof close to the other one of the front light-transmitting plate and the rear light-transmitting plate, the bus wiring layer is attached onto the power generation layer set to form a pin, and the power generation layer set and the bus wiring layer are encapsulated between the front and rear light-transmitting plates by an encapsulation adhesive.

Abstract: Provided are a fusion protein that improves gene editing efficiency and an application thereof. The fusion protein comprises a single-stranded DNA binding protein functional domain, nucleoside deaminase and nuclease. According to CBEs, when carrying our base conversion from C-G to T-A, nucleoside deaminase such as cytosine deaminase carries out deamination by using single-stranded DNA as a substrate, and by re-fusing the single-stranded DNA binding protein functional domain on the fusion protein of the nucleoside deaminase and nuclease, the chance of single-stranded DNA being exposed to the nucleoside deaminase is greatly increased, thereby significantly improving base editing efficiency. The present disclosure provides a breakthrough improvement of single-base gene editing technology and can greatly promote the application thereof in aspects such as gene editing, gene therapy, cell therapy, animal model making, and crop genetic breeding.

Abstract: A heating device includes a PCB (10), at least one heating element (30, 31, 32), bus bars (60a, 60b, 60c) and a terminal pin (40) and a terminal plate (70). At least a portion of the PCB (10) extends out of a PCB housing (20). The terminal pin (40) is disposed in a connector housing (50) disposed at least partially outside the PCB housing (20). At least one of the connector housing (50) and the portion of the PCB (10) extending out of the PCB housing (20) includes at least one support element (52) to support the connector housing (50) in a pre-determined position with respect to the PCB (10).

Abstract: A full probability-based seismic risk analysis method for a tunnel under fault dislocation comprises: evaluating a magnitude-frequency relationship of a fault; obtaining a probabilistic seismic risk curve of a fault dislocation; calculating a series of bending moments of a tunnel lining under different fault dislocations; obtaining a series of damage index values RM of the tunnel; obtaining a vulnerability model of the tunnel damaged by fault dislocation; calculating a probabilistic risk that the tunnel crossing the fault is damaged due to the dislocation of the active fault; obtaining a probability P that the damage state is equal to or higher than a certain damage state within a specified period; and using the results to guide the assessment of the seismic risk of the tunnel crossing the fault. Modeling and analysis can be performed according to the actual situation of the tunnel crossing the fault with different factors.

Abstract: Methods of assessing or monitoring the effect, efficacy, responsiveness to treatment, and/or determining a dose or dosing regimen of therapeutic agents, such as integrin beta7 antagonists, for the treatment of gastrointestinal inflammatory disorders are provided. In certain aspects, methods of using integrin beta7 subunit-containing receptor occupancy by the integrin beta7 antagonist on colonic lymphocytes as an indicator (“biomarker”) of the effect, efficacy, or responsiveness to treatment, and/or as a means to determine dosing or dosing regimens of therapeutic agents such as beta7 integrin antagonists for the treatment of gastrointestinal inflammatory disorders are provided. In certain aspects, methods of assessing the effect, efficacy, or responsiveness to beta7 integrin antagonist treatment by measuring gene expression levels of one or more integrin receptor ligands, lymphocyte genes, cytokine genes, or the number of alphaE-positive cells in intestinal crypt epithelium are provided.

Abstract: An aluminum material, a preparation method thereof, and a bowl-shaped aluminum block are provided in the present disclosure, which relates to the technical field of alloys. Controlling the amount of manganese to 0.03-0.5 wt % in the present disclosure can improve the structure and enhance the impact mechanical properties of aluminum material; nickel can improve the strength and rust resistance of aluminum material, strontium can form an aluminum-strontium combination to adjust the crystal orientation of the metal lattice, which can improve molding and greatly enhance flexibility, and zirconium has a synergistic effect, which can improve the corrosion resistance of aluminum material, and improve surface gloss. The aluminum material provided by the present disclosure has a hardness of 23-30 HB, a tensile strength of 70-100 MPa, a yield strength of 35-59 MPa, and an elongation at break of 40-60%.

Abstract: In some embodiments, a method receives a request for supplemental content to be provided in association with main content. The method selects an instance of supplemental content based on a long-term reward metric and a short-term reward metric. The long-term reward metric is based on feedback from delivery of a plurality of instances of supplemental content and a delivery status for a delivery constraint of one instance of supplemental content. The short-term reward metric is based on feedback from delivery of the one instance of supplemental content. The long-term reward metric is based on feedback from delivery of a plurality of instances of supplemental content and the short-term reward metric is based on feedback from delivery of one instance of supplemental content. The instance of supplemental content is provided to a client device.

Abstract: An apparatus, system and method for calibrating an x-ray apparatus including acquiring sinogram data by scanning a symmetrical phantom using a plurality of detector channels; generating mirror-copied sinogram data by mirror-copying at least one of first sinogram data and second sinogram data of the acquired sinogram data, wherein the first sinogram data and the second sinogram data are generated by dividing the sinogram data at a center detector channel of the plurality of detector channels; outputting a first reconstructed image by reconstructing the mirror-copied sinogram data; and determining a calibration parameter based on the first reconstructed image.

Abstract: Disclosed are a pharmaceutical composition and an application thereof. The pharmaceutical composition of the present invention comprises the following components in parts by weight: 2-20 parts of phenolic acids, 0.5-5 parts of flavonoids, 0.005-0.5 part of tanshinones, 5-20 parts of saponins, and 10-18 parts of volatile oils. The pharmaceutical composition has the functions of protecting against myocardial damage and treating heart failure.