Abstract: Hyper-inflammatory responses can lead to a variety of diseases including sepsis. It is now shown that extracellular histones released in response to inflammatory challenge are mediators contributing to endothelial dysfunction, organ failure and death during sepsis. As such, they can be targeted pharmacologically by inhibitors, as well as used as biomarkers for prognosis of sepsis and other diseases.

Abstract: Hyper-inflammatory responses can lead to a variety of diseases including sepsis. It is now shown that extracellular histones released in response to inflammatory challenge are mediators contributing to endothelial dysfunction, organ failure and death during sepsis. As such, they can be targeted pharmacologically by inhibitors, as well as used as biomarkers for prognosis of sepsis and other diseases.

Abstract: The field of advanced wastewater treatment, and more specifically, to a natural pyrrhotite biofilter and a method for utilizing same to synchronously remove nitrate-nitrogen and phosphorus from water is provided. The method includes the following steps: (1) preparation of the packing material and construction of the biofilter; (2) start-up of the biofilter; (3) operation of the biofilter. The method disclosed in the present invention on the one hand takes pyrrhotite as the electron donor to help sulfur-based autotrophic denitrifying bacteria reduce nitrates into nitrogen gas, and on the other hand utilizes pyrrhotite and its oxidates to eliminate phosphorus through adsorption and chemical precipitation. Therefore, this method realizes synchronous removal of nitrate-nitrogen and phosphorus in water.

Abstract: Hyper-inflammatory responses can lead to a variety of diseases including sepsis. It is now shown that extracellular histones released in response to inflammatory challenge are mediators contributing to endothelial dysfunction, organ failure and death during sepsis. As such, they can be targeted pharmacologically by inhibitors, as well as used as biomarkers for prognosis of sepsis and other diseases.

Abstract: A coating system and a coating method are provided. The coating system includes: a coating device, a detecting device, and an adjusting device, wherein, the coating device is configured for applying a coating material on a substrate; the detecting device is configured for detecting a film thickness of the coating material at a measuring point when the coating device is applying the coating material and sending the detected film thickness to the adjusting device; the adjusting device is configured for selectively generating a preset feeding speed according to the film thickness and sends the preset feeding speed to the coating device. The coating system and the coating method are capable of adjusting film thickness in real time.

Abstract: A method for correcting a fracture model of a reservoir includes receiving a seismic signal from seismic events due to a plurality of stimulated reservoir stages to provide detected seismic event information and estimating a number of undetected seismic events and a magnitude for each of the undetected seismic events to provide undetected seismic event information for each stage. The detected seismic event information and the undetected seismic event information provide corrected seismic event information for each stage. The method further includes calculating a scaling factor for each stage using a scalar property of the corresponding stage and a reference stage scalar property, applying the scaling factor for each stage to the corrected seismic event information to provide scaled seismic event information for each stage, and correcting the fracture model with the scaled seismic event information for each stage to provide a corrected fracture model.

Abstract: A conversation-based computing system may include a back-end computing module, a design module, and an execution module. The design module may be configured to provide a graphical user interface through which different conversation models are defined in metadata. Each model may include a topic containing respective goals, where the goals are associated with respective conversation flows that define respective dialogs that directs conversations toward the associated goals. Each model may also define references to topic-specific content stored in the back-end module. The execution module may be configured to execute a particular model between the system and a front-end computing device and set up integration of a live agent into the model. Execution of the model may involve, in part, carrying out, in an at least partially-automated fashion, the flow for the model according to the dialog, the topic-specific content corresponding to the model, and communicating using a specific communication protocol.

Abstract: A conversation-based computing system may include a back-end computing module, a design module, and an execution module. The design module may be configured to provide a graphical user interface through which different conversation models are defined in metadata. Each model may include a topic containing respective goals, where the goals are associated with respective conversation flows that define respective dialogs that directs conversations toward the associated goals. Each model may also define references to topic-specific content stored in the back-end module. The execution module may be configured to execute a particular model between the system and a front-end computing device and set up integration of a live agent into the model. Execution of the model may involve, in part, carrying out, in an at least partially-automated fashion, the flow for the model according to the dialog, the topic-specific content corresponding to the model, and communicating using a specific communication protocol.

Abstract: Hyper-inflammatory responses can lead to a variety of diseases including sepsis. It is now shown that extracellular histones released in response to inflammatory challenge are mediators contributing to endothelial dysfunction, organ failure and death during sepsis. As such, they can be targeted pharmacologically by inhibitors, as well as used as biomarkers for prognosis of sepsis and other diseases.

Abstract: A method of estimating one or more properties of an earth formation includes disposing a carrier in a borehole in an earth formation as part of an energy industry operation, receiving borehole fluid from the borehole, estimating at least one property of the borehole fluid associated with one or more intervals along the borehole, and generating a mud log that indicates values of the at least one property at the one or more intervals, the at least one property including at least one of gas content and cuttings content. The method also includes estimating, by a processor, one or more properties of the formation based on the mud log, the one or more properties selected from at least one of lithology, permeability, total organic carbon and brittleness, and controlling one or more operational parameters of the energy industry operation based on the one or more properties of the formation.

Abstract: An embodiment of a method for constructing a fracture network includes: receiving seismic data collected from a stimulation operation in an earth formation, the seismic data including seismic event data including a first seismic event associated with a first time increment and a second seismic event associated with a subsequent second time increment; and constructing a fracture network model. The model is constructed by: constructing an initial portion of the model based on the first seismic event; and subsequently updating the initial portion of the model based on the second seismic event.

Abstract: Methods, software programs and systems for extending and modifying software functionality, and, more particularly, for using one or more patterns for an enterprise software object to express desired functionality and configuration, and to generate the enterprise software object using the patterns, in an enterprise environment are disclosed. A method according to certain of these embodiments includes selecting one or more patterns from a number of patterns, where the one or more patterns are for an enterprise software object. The enterprise software object can then be generated. The enterprise software object is generated using the one or more patterns. Each of the patterns is configured to describe a solution within a corresponding one of a number of problem domains.

Abstract: The field of advanced wastewater treatment, and more specifically, to a natural pyrrhotite biofilter and a method for utilizing same to synchronously remove nitrate-nitrogen and phosphorus from water is provided. The method includes the following steps: (1) preparation of the packing material and construction of the biofilter; (2) start-up of the biofilter; (3) operation of the biofilter. The method disclosed in the present invention on the one hand takes pyrrhotite as the electron donor to help sulfur-based autotrophic denitrifying bacteria reduce nitrates into nitrogen gas, and on the other hand utilizes pyrrhotite and its oxidates to eliminate phosphorus through adsorption and chemical precipitation. Therefore, this method realizes synchronous removal of nitrate-nitrogen and phosphorus in water.

Abstract: A method for correcting a fracture model of a reservoir includes receiving a seismic signal from seismic events due to a plurality of stimulated reservoir stages to provide detected seismic event information and estimating a number of undetected seismic events and a magnitude for each of the undetected seismic events to provide undetected seismic event information for each stage. The detected seismic event information and the undetected seismic event information provide corrected seismic event information for each stage. The method further includes calculating a scaling factor for each stage using a scalar property of the corresponding stage and a reference stage scalar property, applying the scaling factor for each stage to the corrected seismic event information to provide scaled seismic event information for each stage, and correcting the fracture model with the scaled seismic event information for each stage to provide a corrected fracture model.

Abstract: Hyper-inflammatory responses can lead to a variety of diseases including sepsis. It is now shown that extracellular histones released in response to inflammatory challenge are mediators contributing to endothelial dysfunction, organ failure and death during sepsis. As such, they can be targeted pharmacologically by inhibitors, as well as used as biomarkers for prognosis of sepsis and other diseases.

Abstract: A method for estimating a volume of a stimulated reservoir includes receiving a seismic signal having a magnitude from each detected microseismic event in a plurality of detected microseismic events in an earth formation to provide detected microseismic event information. The seismic signal is received by an array of seismic receivers. The method further includes estimating a number of undetected microseismic events and a magnitude for each of the undetected microseismic events to provide undetected microseismic event information where the number of undetected microseismic events and corresponding magnitudes are estimated using each of the detected microseismic events and corresponding magnitudes. The method further includes estimating the stimulated reservoir volume using the detected microseismic event information and the undetected microseismic event information.

Abstract: A method for estimating a volume of a stimulated reservoir includes receiving a seismic signal from each microseismic event in a plurality of microseismic events in an earth formation by an array of seismic receivers. The method further includes representing each microseismic event by a plurality of markers in the three-dimensional space. A spatial distribution of the markers represents a volume of rock influenced by a microseismic event, wherein the volume and a location of each event are derived from the seismic signal. The method further includes calculating a scalar attribute for each marker in the plurality of markers, dividing the three-dimensional space into a plurality of three-dimensional grid cells, and summing the scalar attributes for all the markers in each grid cell to provide a total scalar attribute for each grid cell.

Abstract: An embodiment of a method for constructing a fracture network includes: receiving seismic data collected from a stimulation operation in an earth formation, the seismic data including seismic event data including a first seismic event associated with a first time increment and a second seismic event associated with a subsequent second time increment; and constructing a fracture network model. The model is constructed by: constructing an initial portion of the model based on the first seismic event; and subsequently updating the initial portion of the model based on the second seismic event.

Abstract: Hyper-inflammatory responses can lead to a variety of diseases including sepsis. It is now shown that extracellular histones released in response to inflammatory challenge are mediators contributing to endothelial dysfunction, organ failure and death during sepsis. As such, they can be targeted pharmacologically by inhibitors, as well as used as biomarkers for prognosis of sepsis and other diseases.

Abstract: Hyper-inflammatory responses can lead to a variety of diseases including sepsis. It is now shown that extracellular histones released in response to inflammatory challenge are mediators contributing to endothelial dysfunction, organ failure and death during sepsis. As such, they can be targeted pharmacologically by inhibitors, as well as used as biomarkers for prognosis of sepsis and other diseases.