Abstract: Peptide ligands for transporting therapeutic agents across the intestinal epithelial barrier that ordinarily are inadequately absorbed and must be delivered by alternative means, which contain an isolated amino acid sequence wherein at least one pair of amino acids are of an opposite charge and the pair members are separated by a spacer of 1-12 amino acid residues including at least one hydrophobic amino acid, and wherein the length of the amino acid sequence is greater than 5 and less than 20 amino acids. Pharmaceutical compositions for gastro-intestinal delivery and methods for the gastrointestinal delivery of poorly absorbed therapeutic agents are also disclosed.

Abstract: A method for inputting signals into a smart TV and a smart interaction system includes displaying a virtual keyboard having a key layout corresponding to that of a physical keyboard used for inputting signals into a smart TV; obtaining from the physical keyboard a first signal, which is generated in response to an operator selecting a physical key on the physical keyboard and is indicative of information on a position of the selected physical key on the physical keyboard; and displaying on the virtual keyboard the position of the selected physical key based on the first signal.

Abstract: A first terminal device and a video display control method are described. The first terminal device includes at least two tuners configured to receive and decode a video; a first display unit configured to display video or image; a first communication unit configured to communicate with a second terminal device; and a first processing unit configured to control the at least two tuners, the first display unit and the first communication unit. The first processing unit chooses one of the at least two tuners as a primary tuner, and displays a first video of the primary tuner on the first display unit, and the first processing unit sets the other tuner of the at least two tuners as slave tuner, and transmits a video of the slave tuner to the second terminal device through the first communication unit so as to be displayed by the second terminal device.

Abstract: An information processing method applied in an electric device is disclosed. The method comprises: acquiring at least one play parameter for characterizing a playing history of a first video from the network side and/or a storage unit of an electric device; generating and displaying a play progress bar corresponding to the first video on a display unit of the electric device based on the at least one play parameter, wherein the play progress bar has at least a first portion displayed in a first pattern and a second portion displayed in a second pattern different from the first pattern. Such solution provided by the invention provides a new display approach for the play progress bar, and addresses the technical problem that a video can only be segmented or prompted by the play progress bar of the video according to the content of the video.

Abstract: The present disclosure discloses a projection method and an electronic device, belong to an image processing field. The method comprises: obtaining a first image, and obtaining an adjustment instruction, wherein the first image corresponds to first content; adjusting the first image to a second image according to the adjustment instruction, the second image comprising a target image corresponding to the first content; and projecting the second image; wherein when the second image is projected onto intersected planes formed by at least two planes, if an edge of the target image is intersected with an intersection line of the intersected planes, the edge of the target image is or is approximately perpendicular to the intersection line of the intersection planes.

Abstract: Robust content-based decision-making support is enabled by software with a customizable knowledge base. Utilizing proprietary information contained within a knowledge base, the software enables users to search the indexed database by feature, example firm, or pattern and update the knowledge base based on the results. The information contained in the knowledge base enables results to be ranked by relevance and enables other feedback to be provided. The system and methods provide process support by helping financial professionals identify, analyze, and construct data analysis patterns based on individual domain knowledge and preferences. The system and methods automatically detect abnormal patterns and automatically analyze their correlations to market events to provide further process support to financial professionals. Using the results of any searching, analysis, and processing, the system and methods provide a neural network or other learning algorithm to provide content-based decision-making support.

Abstract: Peptide ligands for transporting therapeutic agents across the intestinal epithelial barrier that ordinarily are inadequately absorbed and must be delivered by alternative means, which contain an isolated amino acid sequence wherein at least one pair of amino acids are of an opposite charge and the pair members are separated by a spacer of 1-12 amino acid residues including at least one hydrophobic amino acid, and wherein the length of the amino acid sequence is greater than 5 and less than 20 amino acids. Pharmaceutical compositions for gastro-intestinal delivery and methods for the gastrointestinal delivery of poorly absorbed therapeutic agents are also disclosed.

Abstract: The disclosed method calculates video time density functions based on inter-frame mutual information or other similarity measures. The method includes acquiring a video sequence from memory, computing mutual information or other similarity measures between two consecutive frames of the video sequence, and constructing a video temporal density function based on the mutual information or similarity measures. The method enables fast navigation of the video sequence by performing a temporal quantization of the video time density function to determine a set of quanta. The video sequence can be navigated using the nearest neighbor video frames to the set of quanta. The method enables thumbnail extraction of a video sequence using statistical modeling by performing a temporal quantization of the video time density function to segment video sequence in time domain and using mixture (such as Gaussian mixture and ICA mixture) vector quantization to find the sample frames for each temporal segment.

Abstract: A display method and apparatus and an electronic device are provided, in which a second image is displayed in accordance with a relative relationship between a user and a displaying supporter, i.e., the distance between a first operation object and a second operation object in a first image is different from that in a second image, in the case that the relative relationship satisfies a first preset condition. Therefore, when the distance between the operation objects is too small, the distance between the operation objects is enlarged and then the operation objects are displayed in the second image. When the distance between the operation objects is too large, the distance between the operation objects is reduced and then the operation objects are displayed in the second image. Therefore, the distance between the operation objects changes with the relative relationship between the user and the displaying supporter.

Abstract: Peptide ligands for transporting therapeutic agents across the intestinal epithelial barrier that ordinarily are inadequately absorbed and must be delivered by alternative means, which contain an isolated amino acid sequence wherein at least one pair of amino acids are of an opposite charge and the pair members are separated by a spacer of 1-12 amino acid residues including at least one hydrophobic amino acid, and wherein the length of the amino acid sequence is greater than 5 and less than 20 amino acids. Pharmaceutical compositions for gastro-intestinal delivery and methods for the gastrointestinal delivery of poorly absorbed therapeutic agents are also disclosed.

Abstract: The present invention provides an input method, a smart TV and a smart interaction system. The input method comprises: displaying a virtual keyboard having a key layout corresponding to that of a physical keyboard used for inputting to a smart TV; obtaining from the physical keyboard a first signal that is generated in response to an operator selecting a physical key on the physical keyboard and indicates information on position of the operator on the physical keyboard; and displaying on the virtual keyboard the position of the operator based on the first signal. The physical keyboard is consistent with the virtual keyboard displayed on the smart TV. Thus, each physical key on the physical keyboard can be found in the virtual keyboard. When a physical key on the physical keyboard is selected or triggered, the input process can be viewed visually on the smart TV. In this way, the input speed can be increased and the user experience can be improved.

Abstract: The disclosed method calculates video time density functions based on inter-frame mutual information or other similarity measures. The method includes acquiring a video sequence from memory, computing mutual information or other similarity measures between two consecutive frames of the video sequence, and constructing a video temporal density function based on the mutual information or similarity measures. The method enables fast navigation of the video sequence by performing a temporal quantization of the video time density function to determine a set of quanta. The video sequence can be navigated using the nearest neighbor video frames to the set of quanta. The method enables thumbnail extraction of a video sequence using statistical modeling by performing a temporal quantization of the video time density function to segment video sequence in time domain and using mixture (such as Gaussian mixture and ICA mixture) vector quantization to find the sample frames for each temporal segment.

Abstract: The present application discloses methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), systemic JIA (sJIA), polyarticular course JIA (pcJIA), systemic sclerosis, or giant cell arteritis (GCA), with subcutaneously administered antibody that binds interleukin-6 receptor (anti-IL-6R antibody). In particular, it relates to identification of a fixed dose of anti-IL-6R antibody, e.g. tocilizumab, which is safe and effective for subcutaneous administration in patients with IL-6-mediated disorders. In addition, formulations and devices useful for subcutaneous administration of an anti-IL-6R antibody are disclosed.

Abstract: The present application discloses methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), systemic JIA (sJIA), polyarticular course JIA (pcJIA), systemic sclerosis, or giant cell arteritis (GCA), with subcutaneously administered antibody that binds interleukin-6 receptor (anti-IL-6R antibody). In particular, it relates to identification of a fixed dose of anti-IL-6R antibody, e.g. tocilizumab, which is safe and effective for subcutaneous administration in patients with IL-6-mediated disorders. In addition, formulations and devices useful for subcutaneous administration of an anti-IL-6R antibody are disclosed.

Abstract: The present application discloses methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), systemic JIA (sJIA), polyarticular course JIA (pcJIA), systemic sclerosis, or giant cell arteritis (GCA), with subcutaneously administered antibody that binds interleukin-6 receptor (anti-IL-6R antibody). In particular, it relates to identification of a fixed dose of anti-IL-6R antibody, e.g. tocilizumab, which is safe and effective for subcutaneous administration in patients with IL-6-mediated disorders. In addition, formulations and devices useful for subcutaneous administration of an anti-IL-6R antibody are disclosed.

Abstract: The present application discloses an operation control method and an electronic apparatus. The operation control method is applied to a first electronic apparatus having at least two operating modes, i.e. a first operating mode and a second operating mode. In the operation control method, the state of a second electronic apparatus is firstly detected; a corresponding control instruction is generated according to the detection result; and the first electronic apparatus is controlled to enter the first operating mode or the second operating mode according to the control instruction; if the detection result meets a preset condition, the first electronic apparatus enters the corresponding operating mode automatically, thereby it is avoided to select the mode every time the user uses the first electronic apparatus, and it is more convenient for using the first electronic apparatus.

Abstract: A first terminal device and a video display control method are described. The first terminal device includes at least two tuners configured to receive and decode a video; a first display unit configured to display video or image; a first communication unit configured to communicate with a second terminal device; and a first processing unit configured to control the at least two tuners, the first display unit and the first communication unit. The first processing unit chooses one of the at least two tuners as a primary tuner, and displays a first video of the primary tuner on the first display unit, and the first processing unit sets the other tuner of the at least two tuners as slave tuner, and transmits a video of the slave tuner to the second terminal device through the first communication unit so as to be displayed by the second terminal device.

Abstract: Peptide ligands for transporting therapeutic agents across the intestinal epithelial barrier that ordinarily are inadequately absorbed and must be delivered by alternative means, which contain an isolated amino acid sequence wherein at least one pair of amino acids are of an opposite charge and the pair members are separated by a spacer of 1-12 amino acid residues including at least one hydrophobic amino acid, and wherein the length of the amino acid sequence is greater than 5 and less than 20 amino acids. Pharmaceutical compositions for gastro-intestinal delivery and methods for the gastrointestinal delivery of poorly absorbed therapeutic agents are also disclosed.

Abstract: The present application discloses methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), systemic JIA (sJIA), polyarticular course JIA (pcJIA), systemic sclerosis, or giant cell arteritis (GCA), with subcutaneously administered antibody that binds interleukin-6 receptor (anti-IL-6R antibody). In particular, it relates to identification of a fixed dose of anti-IL-6R antibody, e.g. tocilizumab, which is safe and effective for subcutaneous administration in patients with IL-6-mediated disorders. In addition, formulations and devices useful for subcutaneous administration of an anti-IL-6R antibody are disclosed.

Abstract: Robust content-based financial data processing is enabled by software with a customizable knowledge base. The software indexes a publicly or privately available financial database based on the content of the database records. Utilizing proprietary information contained within a knowledge base, the software enables users to search the indexed database by feature, example firm, or pattern. The information contained in the knowledge base enables results to be ranked by relevance. Moreover, users provide feedback about search results to enhance the knowledge base. Software analyzes data by using adaptive signal processing to remove market trends or noise and enable complicated market research.