Abstract: The present disclosure provides a hydrocracking catalyst, a method for preparing the same and a use of the same, and a method for hydrocracking catalytic diesel oil. The catalyst comprises a support, an active metal component, and carbon, wherein, based on the total weight of the catalyst, the content of the support is 60 to 90 wt %, the content of the active metal component calculated in metal oxides is 15 to 40 wt %, and the content of carbon calculated in C element is 1 to 5 wt %; measured with an infrared acidimetric estimation method, the acid properties of the hydrocracking catalyst are: the total infrared acid amount is 0.4 to 0.8 mmol/g, wherein, the infrared acid amount of strong acid with desorption temperature greater than 350° C. is 0.08 mmol/g or lower, and the ratio of the total infrared acid amount to the infrared acid amount of strong acid with desorption temperature greater than 350° C. is 5 to 50.

Abstract: Peptide ligands for transporting therapeutic agents across the intestinal epithelial barrier that ordinarily are inadequately absorbed and must be delivered by alternative means, which contain an isolated amino acid sequence wherein at least one pair of amino acids are of an opposite charge and the pair members are separated by a spacer of 1-12 amino acid residues including at least one hydrophobic amino acid, and wherein the length of the amino acid sequence is greater than 5 and less than 20 amino acids. Pharmaceutical compositions for gastro-intestinal delivery and methods for the gastrointestinal delivery of poorly absorbed therapeutic agents are also disclosed.

Abstract: The present application discloses methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), systemic JIA (sJIA), polyarticular course JIA (pcJIA), systemic sclerosis, or giant cell arteritis (GCA), with subcutaneously administered antibody that binds interleukin-6 receptor (anti-IL-6R antibody). In particular, it relates to identification of a fixed dose of anti-IL-6R antibody, e.g. tocilizumab, which is safe and effective for subcutaneous administration in patients with IL-6-mediated disorders. In addition, formulations and devices useful for subcutaneous administration of an anti-IL-6R antibody are disclosed.

Abstract: The present disclosure discloses an information processing method and an electronic device. The method comprises: detecting and acquiring a first touch operation on a touch display unit of the electronic device when M display objects are displayed on the touch display unit, wherein M is an integer greater than or equal to 1; and controlling N of the M display objects to be in a selected state in response to the first touch operation, and generating and executing a first operation instruction for implementing a first operation on the N display objects, wherein N is a positive integer less than or equal to M.

Abstract: The instant invention relates to polyethylene glycol-based dendrons, otherwise known as PEGtide dendrons, compositions thereof and methods of use.

Abstract: The present invention relates to methods for improving fermentation processes, including increasing product yield, reduced viscosity, and/or reduced foaming.

Abstract: An information processing method applied in an electric device is disclosed. The method comprises: acquiring at least one play parameter for characterizing a playing history of a first video from the network side and/or a storage unit of an electric device; generating and displaying a play progress bar corresponding to the first video on a display unit of the electric device based on the at least one play parameter, wherein the play progress bar has at least a first portion displayed in a first pattern and a second portion displayed in a second pattern different from the first pattern. Such solution provided by the invention provides a new display approach for the play progress bar, and addresses the technical problem that a video can only be segmented or prompted by the play progress bar of the video according to the content of the video.

Abstract: This invention provides multimeric nanocarrier for in vivo delivery of a bioactive agent, comprising at least two peptide monomers reversibly or irreversibly linked with one or more of said bioactive agents, wherein said two or more of said peptide monomers are covalently linked by a biodegradable difunctional moiety, as well as methods of using this nanocarrier.

Abstract: Semiconductor devices and fabrication methods are provided. In a semiconductor device, a semiconductor substrate includes a first electrode layer having a top surface coplanar with a top surface of the semiconductor substrate. A sacrificial layer is formed on the semiconductor substrate and the first electrode layer. A first mask layer made of a conductive material is formed on the sacrificial layer. The first mask layer and the sacrificial layer are etched until a surface of the first electrode layer is exposed to form openings through the first mask layer and the sacrificial layer. A cleaning process is performed to remove etch byproducts adhered to a surface of the first mask layer and adhered to sidewalls and bottom surfaces of the openings. Conductive plugs are formed in the openings after the cleaning process.

Abstract: A display method and apparatus and an electronic device are provided, in which a second image is displayed in accordance with a relative relationship between a user and a displaying supporter, i.e., the distance between a first operation object and a second operation object in a first image is different from that in a second image, in the case that the relative relationship satisfies a first preset condition. Therefore, when the distance between the operation objects is too small, the distance between the operation objects is enlarged and then the operation objects are displayed in the second image. When the distance between the operation objects is too large, the distance between the operation objects is reduced and then the operation objects are displayed in the second image. Therefore, the distance between the operation objects changes with the relative relationship between the user and the displaying supporter.

Abstract: The disclosed method calculates video time density functions based on inter-frame mutual information or other similarity measures. The method includes acquiring a video sequence from memory, computing mutual information or other similarity measures between two consecutive frames of the video sequence, and constructing a video temporal density function based on the mutual information or similarity measures. The method enables fast navigation of the video sequence by performing a temporal quantization of the video time density function to determine a set of quanta. The video sequence can be navigated using the nearest neighbor video frames to the set of quanta. The method enables thumbnail extraction of a video sequence using statistical modeling by performing a temporal quantization of the video time density function to segment video sequence in time domain and using mixture (such as Gaussian mixture and ICA mixture) vector quantization to find the sample frames for each temporal segment.

Abstract: The present disclosure provides an information processing method and electronic device. The method comprises: displaying an indicator at a first location on a display area of a first electronic device at a first timing; acquiring a first operation data corresponding to a second timing which is later than the first timing, and updating to display the indicator at a second location on the display area different from the first location; acquiring a second operation data corresponding to a third timing which is later than the second timing when the second location is located on a border of the display area; and performing a predetermined process such that the indicator is displayed at a third location on the display area at a fourth timing when the pointing of the second electronic device re-enters the display area which is later than the third timing, the third location matching with the pointing at the fourth timing.

Abstract: A display method and an electronic device are disclosed in the application. The method includes: detecting, by a first acquisition unit, operation data, while displaying a first part of an output content on a display unit; acquiring, by a second acquisition unit, first focus data of an object user within a set range watching the output content, wherein the focus data indicates a position of the display unit corresponding to a focus of the object user; and displaying a second part of the output content, based on the operation data and the first focus data, wherein the second part is different from the first part.

Abstract: A display method and an electronic apparatus are provided. The method includes: displaying a first display page via a display device, where the first display page includes a first region; detecting a first sliding operation and a second sliding operation on the display device with respect to the first display page; determining whether the first sliding operation and the second sliding operation satisfy a set of predetermined conditions; and controlling a display size of the first region according to the first sliding direction or the second sliding direction, if the first sliding operation and the second sliding operation satisfy the set of predetermined conditions.

Abstract: The application provides an information processing method and an electronic device. The information processing method comprises: monitoring location information of a characteristic point with respect to a first interface displayed on a first electronic device; determining whether the location information of the characteristic point satisfies a preset condition; and keeping the displayed content of the first interface unchanged, and pre-loading first data corresponding to the characteristic point if the location information of the characteristic point satisfies the preset condition, so as to enable second content corresponding to the pre-loaded first data to be displayed on the first electronic device upon the first electronic device receives a switching operation corresponding to the first data.

Abstract: The disclosure provides a display method and an electronic device. The display method includes: detecting whether display contents are to be displayed via a display unit of the electronic device, determining a first region corresponding to a gazing position of a user on the display unit, determining a second region on the display unit based on the first region, and displaying the display contents in the second region.

Abstract: A method for display control and an electronic device are provided. The method includes: detecting a first touch operation and a second touch operation performed on a touch sensing unit. A first touch direction corresponding to the first touch operation and a second touch direction corresponding to the second touch operation are obtained. A first control instruction is obtained based on the first touch direction and the second touch direction. That is, in embodiments of the disclosure, the effect of a touch instruction response to two successively performed touch operations is different from the effect of a touch instruction response to two separately performed touch operations.

Abstract: A system and method for enabling information extraction from large data sets (so-called “big data”) according to a new paradigm is disclosed. This system does not generate functions describing why certain inputs result in certain outputs. Instead, it creates incident mappings of inputs to outputs without regard to why inputs result in outputs. These mappings can be distributions or other data sets representative of different outcomes occurring. This enables several useful operations. For example, by providing a data set indicative of outputs that have historically occurred following a particular input, the disclosed system can be used to predict future outcomes with probabilities. For example, if a particular stock price pattern is provided as an input, the system generates an output data set indicating the probabilities of certain price behaviors following that input pattern. This data set can thus be used to predict future behavior. Other useful operations are disclosed herein.

Abstract: Non-Small Cell Lung Carcinomas (NSCLCs) are treated with Gel Micro-Particles (GMPs) that passively accumulate in the lungs and contain Nano-Particles (NPs) combining one or more therapeutic agents that are cytotoxic to the NSCLC with one or more NSCLC active targeting ligands, as well as one or more other optional agents that increase cellular uptake, enhance the pro-apoptotic effect of the chemotherapeutic agent(s), and the like. NPs targeting other cancer cells are also disclosed, as well as NP-containing GMPs that reduce the occurrence of tumor metastasis.

Abstract: Peptide ligands for transporting therapeutic agents across the intestinal epithelial barrier that ordinarily are inadequately absorbed and must be delivered by alternative means, which contain an isolated amino acid sequence wherein at least one pair of amino acids are of an opposite charge and the pair members are separated by a spacer of 1-12 amino acid residues including at least one hydrophobic amino acid, and wherein the length of the amino acid sequence is greater than 5 and less than 20 amino acids. Pharmaceutical compositions for gastro-intestinal delivery and methods for the gastrointestinal delivery of poorly absorbed therapeutic agents are also disclosed.